Clinical trials: Anemia, Iron Deficiency
Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis
A Study of Momelotinib Versus Danazol in Symptomatic and Anemic Myelofibrosis Participants (MOMENTUM)
MOMENTUM is a randomized, double-blind, active control Phase 3 trial intended to confirm the differentiated clinical benefits of the investigational drug momelotinib (MMB) versus danazol (DAN) in symptomatic and anemic…
- Conditions
- Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis
- Trial name
- NCT04173494
- Testing
- Momelotinib, Danazol
- Where
- 167 sites in United States, Australia and 20 more
- Volunteers
- 195 people
- Sponsor
- Sierra Oncology LLC - a GSK company
Anemia, Iron-Deficiency, Inflammatory Bowel Disease
Safety and Efficacy Study of Oral Ferric Maltol Compared to Intravenous Iron To Treat Iron Deficiency Anaemia in IBD
The purpose of this study is to compare the efficacy of ferric maltol and intravenous iron (IVI) Ferric Carboxy Maltose in the treatment of iron deficiency anaemia (IDA) and subsequent maintenance of haemoglobin in subjects with…
- Conditions
- Anemia, Iron-Deficiency, Inflammatory Bowel Disease, Crohn's Disease
- Trial name
- NCT02680756
- Testing
- Ferric Maltol, Ferric Carboxy Maltose
- Where
- 44 sites in United States, Belgium and 4 more
- Volunteers
- 250 people
- Sponsor
- Shield Therapeutics
Renal Failure
Non-invasive Determination of Anemia in Children With Renal Failure
Anemia and inflammation are very common in patients with renal diseases. The most common procedure to detect anemia is to determine blood hemoglobin concentrations.
- Trial name
- NCT02369237
- Volunteers
- 54 people
- Sponsor
- Center for Studies of Sensory Impairment, Aging and Metabolism
Iron-deficiency Anemia (IDA), Pregnancy
Oral Iron Supplementation on Alternate vs. Consecutive Days for Iron Deficiency Anemia in Pregnancy
This will be a randomized clinical trial. Enrolled subjects will be randomized (1:1) into two study arms to receive either daily (Group 1) or alternate day (Group 2) supplementation with one oral pill containing ferrous sulfate…
- Trial name
- NCT06492512
- Testing
- daily ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill, alternate day ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Southern Illinois University
Tourette Syndrome
The Pathophysiology of Tourette Syndrome: a Multimodal Study
The purpose of this study is to characterize the functional and anatomical connectivity changes in Tourette syndrome and its relation with iron deficiency.
- Trial name
- PTS (NCT02497807)
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Obesity, Bariatric Surgery
Effectiveness of a Modified Cost-Effective Dietary Plan in Promoting Weight Loss and Preservation of Lean Body Mass in Patients After Bariatric Surgery
This study will see if a low-cost dietary plan, based on the standard dietary guidelines of the American Society for Metabolic and Bariatric Surgery (ASMBS) and using locally available foods, can help patients lose weight and…
- Conditions
- Obesity, Bariatric Surgery, Nutritional Status, Body Composition
- Trial name
- NCT07111767
- Testing
- Low-Cost Post-Bariatric Diet, Standard High-cost Post-Bariatric Diet
- Where
- Pakistan
- Volunteers
- 122 people
- Sponsor
- Khyber Teaching Hospital
Anaemia
Tranexamic Acid for Anaemia Trial
Anaemia is when the body does not have enough healthy red blood cells to carry oxygen. It is common in women because they lose blood every month during their periods.
- Trial name
- WOMAN-3 (NCT06519422)
- Testing
- Tranexamic Acid 500 MG
- Where
- 3 sites in Nigeria, Pakistan and 1 more
- Volunteers
- 4,000 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Iron Deficiency (Without Anemia), B12 Deficiency Vitamin
Hydroponic Fortification and Dietary App Effect on Nutrients Level (Harvest)
Veganism and vegetarianism have clear benefits where they have a lower risk of many health issues. However, they also have a higher risk of nutrients and vitamin deficiency such as iron and vitamin B12.
- Trial name
- NCT05740462
- Testing
- Recipes consumption, Hydroponic unit
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Iron Deficiency, Fibromyalgia
Blinded Randomized Placebo-Controlled Study Efficacy and Safety of Injectafer in ID Patients With Fibromyalgia
This study investigates the efficacy and safety of an IV iron Injectafer in the treatment of iron deficient patients with fibromyalgia.
- Trial name
- NCT02409459
- Testing
- Injectafer
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- American Regent, Inc.
Disorder of Small Intestine, Gastrointestinal Hemorrhage
European Novel Motorized Spiral Endoscopy Trial
The subject Novel Motorized Spiral Enteroscope (NMSE) represents a new technology which offers all of the advantageous options of spiral enteroscopy with a faster and less invasive approach.
- Conditions
- Disorder of Small Intestine, Gastrointestinal Hemorrhage, Iron Deficiency Anaemia, Crohn's Disease
- Trial name
- ENMSET (NCT02965209)
- Testing
- motorized spiral enteroscopy
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Evangelisches Krankenhaus Düsseldorf
Anemia, Cardiac Surgery
Iron Deficiency and Anemia in Cardiac Surgery
Anemia and preoperative iron deficit in cardiac surgery are associated by an increased volume of transfusion and an increase in complications and/or mortality.
- Trial name
- DFACCVM (NCT04980911)
- Where
- France
- Volunteers
- 1,711 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Pulmonary Hypertension, Iron Deficiency
The Impact of IV Iron on Exercise Capacity and Quality of Life in Pulmonary Hypertension
Pulmonary hypertension (PH) is a condition characterized by elevated blood pressure in the pulmonary arteries. This leads to symptoms such as shortness of breath and a significantly reduced exercise capacity, resulting in a very…
- Trial name
- IRON-PH (NCT07359599)
- Testing
- Ferric Carboxymaltose (FCM), Sodium Chloride (NaCl) 0.9 %
- Where
- 7 sites in Belgium
- Volunteers
- 306 people
- Sponsor
- Ziekenhuis Oost-Limburg
Kidney Failure, Chronic, Anemia, Iron-Deficiency
Comparison Between Effects of Two Iron Preparations on Protein in the Urine
This study will compare the effects of sodium ferric gluconate complex and iron sucrose on urine concentrations of various chemicals including protein
- Trial name
- NCT00534144
- Testing
- iron sucrose injection, USP, sodium ferric gluconate complex in sucrose injection
- Where
- 13 sites in United States, Puerto Rico
- Volunteers
- 74 people
- Sponsor
- Watson Pharmaceuticals
Iron Deficiency Anemia
Amino Acid Chelated Iron Versus Ferrous Fumarate in the Treatment of Iron Deficiency Anemia With Pregnancy: Randomized Controlled Trial
Anemia is the commonest hematological disorder that occurs in pregnancy. According to the recent standard laid down by 'WHO', anemia is present when the Hemoglobin (Hb) concentration in the peripheral blood is 11 gm/dl or less.
- Trial name
- NCT03830034
- Testing
- Amino Acid chelated iron tab 15 mg, Ferrous Fumarate tab 350 mg( 115 mg elemental iron)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Ain Shams University
Pulmonary Arterial Hypertension, Iron Deficiency
IV Iron Replacement for Iron Deficiency in Idiopathic Pulmonary Arterial Hypertension (IPAH) Patients
This study will establish whether intravenous iron replacement has clinical benefit in idiopathic pulmonary arterial hypertension.
- Trial name
- NCT01447628
- Testing
- Saline, Ferinject or CosmoFer
- Where
- 5 sites in China, Germany and 1 more
- Volunteers
- 56 people
- Sponsor
- Imperial College London
Nutritional Deficiencies, Developmental Delay
Project Grow Smart: Intervention Trial of Multiple Micronutrients and Early Learning Among Infants in India
Project Grow Smart evaluates the impact fortification with multiple micronutrient powders (MNP) vs. placebo (one vitamin) on child development (primary outcome) and on micronutrient status, growth, and morbidity (secondary…
- Trial name
- GrowSmart (NCT01660958)
- Testing
- MNP, Early Learning
- Where
- India
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Heart Failure, Systolic, Iron Deficiencies
IV Iron and SGLT2 Inhibitor on Ventricular Function and Myocardial Iron Content in Heart Failure With Iron Deficiency
Background. Treatment with intravenous iron has been shown to improve symptoms, functional capacity, and quality of life in patients with heart failure with reduced ejection fraction (HFrEF) and iron deficiency.
- Trial name
- COMBINED-HF (NCT06434025)
- Testing
- Iron Carboxymaltose, Dapagliflozin 10mg Tab
- Where
- Brazil
- Volunteers
- 99 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Anemia, Skin Condition
The Efficacy of Minayo Iron-rich Nutritional Gummies on Female Anemia, Skin Condition and Qi-blood Deficiency Syndrome
The goal of this randomized, double-blind, placebo controlled study is to learn about the efficacy of Minayo Iron-rich Nutritional Gummies on females who are aged 18-45 and suffer nutritional Anemia, skin condition and Qi-blood…
- Conditions
- Anemia, Skin Condition, Qi-blood Deficiency Syndrome
- Trial name
- NCT06869824
- Testing
- Minayo Iron-rich Nutritional Gummies, Common Gummies
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hangzhou Agile Groups Network Technology Co., Ltd.
Hypertension, Hand Grip Strength
The Effect of an Oral Nutritional Supplement on the Nutritional and Health Outcomes of the Elderly
I am conducting this research to find out if a peanut based food that is ready to use would improve the nutritional and health outcomes of the elderly when they consume it daily for 12 weeks.
- Conditions
- Hypertension, Hand Grip Strength, Body Weight, Iron Deficiency
- Trial name
- NCT06773975
- Testing
- Oral nutritional supplementation
- Where
- Ghana
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Ghana
Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF)
IRONICA: IRON Repletion In Heart Failure - A Comparison of Oral and IV Approaches
The goal of this clinical trial is to learn which iron treatment works better for adults with congestive heart failure and low iron levels: intravenous (IV) iron given through a vein or oral (PO) iron taken by mouth.
- Conditions
- Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF), Heart Failure With Preserved Ejection Fraction (HFPEF), Iron Deficiency
- Trial name
- IRONICA (NCT07053475)
- Testing
- Ferric Carboxymaltose, Ferrous Sulfate
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Syed Hamza Mufarrih