Clinical trials: Anemia in Pregnancy
Breast Cancer, Ovarian Cancer
Phase I of Carboplatin-Olaparib Followed by Olaparib Monotherapy in Advanced Cancer
A phase I trial to determine the recommended phase two dose of the combination of carboplatin and olaparib.
- Conditions
- Breast Cancer, Ovarian Cancer, Advanced Cancer
- Trial name
- REVIVAL (NCT02418624)
- Testing
- carboplatin, olaparib
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- The Netherlands Cancer Institute
Anemia, Renal Impairment
Blood Products in Cardiac Surgery
Blood transfusion is a common procedure essential for the treatment of patients undergoing cardiac surgery. Inappropriate transfusions, however, not only incur needless healthcare costs, but increase unnecessary risks due to…
- Conditions
- Anemia, Renal Impairment, Thrombocytopenia
- Trial name
- BiCS (NCT02068755)
- Volunteers
- 31,000 people
- Sponsor
- University of Turku
Iron Deficiency Anemia of Pregnancy
Lactoferrin Versus Ferrous Fumarate for Treatment of Mild to Moderate Iron Deficiency Anemia During Pregnancy
This study will conducted to evaluate and comparison between the effectiveness, safety and acceptability of lactoferrin alone, ferrous fumarate alone and combination of both for the treatment of mild to moderate IDA during…
- Trial name
- NCT03484845
- Testing
- Lactoferrin and ferrous fumarate
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
Anemia of Pregnancy
Prevalence and Determinants of Anemia During the Third Trimester of Pregnancy
This cross-sectional study was conducted on 383 pregnant women who attended the antenatal care clinic during their third trimester at Beni-Suef University Hospital. A proper history was taken from each participant.
- Trial name
- NCT05479799
- Where
- Egypt
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Hypertensive Emergency-associated Hemolytic Uremic Syndrome
Eculizumab in Hypertensive Emergency-associated Hemolytic Uremic Syndrome
Hemolytic and uremic syndrome (HUS) is a clinic-biological syndrome related to thrombotic microangiopathy affecting predominantly the kidney.
- Trial name
- HYPERSHU (NCT05726916)
- Testing
- Soliris®, Renin angiotensin system blockers
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Perinatal Mortality, Stillbirth
Impact of Prenatal Vitamin/Mineral Supplements on Perinatal Mortality
The purpose of this study is to determine whether a daily prenatal supplement of iron plus folic acid or a daily prenatal supplement with multiple vitamins and minerals given to women from their first prenatal visit through…
- Conditions
- Perinatal Mortality, Stillbirth, Neonatal Mortality
- Trial name
- NCT00133744
- Testing
- folic acid, folic acid plus iron, supplements with multiple vitamins and minerals
- Where
- 5 sites in China
- Volunteers
- 18,962 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Stroke (CVA) or TIA, Diabetes
Risk Factors, Costs, and Impacts of ED Boarding
The goal of this observational study is to learn about the risk factors, costs, and operational impacts of emergency department boarding (patients admitted to the hospital but remaining in the emergency department awaiting…
- Conditions
- Stroke (CVA) or TIA, Diabetes, Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease)
- Trial name
- NCT07532564
- Where
- United States
- Volunteers
- 30,486 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Anemia, Kidney Disease
Safety and Efficacy Study for AKB-6548 in Participants With Chronic Kidney Disease and Anemia
The purpose of this study is to evaluate the safety, pharmacodynamics and pharmacokinetics of repeat doses of orally administered AKB-6548 in pre-dialysis participants with anemia.
- Trial name
- NCT01235936
- Testing
- AKB-6548
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Akebia Therapeutics
Pregnancy, Iron Deficiency
Bovine Lactoferrin to Prevent and Cure Iron Deficiency and Iron Deficiency Anemia in Complicated Pregnancies
The purpose of this study is to determine whether bovine lactoferrin is effective in preventing and curing iron deficiency and iron deficiency anemia in Hereditary Thrombophilia affected women during pregnancy.
- Conditions
- Pregnancy, Iron Deficiency, Iron Deficiency Anemia
- Trial name
- NCT01221844
- Testing
- Lattoglobina (Grunenthal) containing bLf, FerroGrad by Abbott
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Clinica Fabia Mater
Anemia, Anemia, Iron Deficiency
Iron Deficiency Anemia and Non-iron Deficiency Anemia in Pregnancy in India
This is a sub-study nested into the existing NICHD Global Network for Women's \& Children's Health Research Maternal Newborn Health (MNH) registry that is a prospective, observational population-based registry in Eastern…
- Conditions
- Anemia, Anemia, Iron Deficiency, Anemia of Pregnancy
- Trial name
- IDA & NIDA (NCT04708665)
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Kidney Failure, Chronic, Anemia
Audit of the Effect of Changing From IV to SC Administration of ESA's in Haemodialysis Patients
The purpose of this study is to audit the effects of changing all hemodialysis patients from intravenous to subcutaneous administration of ESA's, to ensure that a cost-saving is achieved and that this does not occur at the…
- Trial name
- NCT00382044
- Testing
- Eprex; Neorecormon; Aranesp
- Where
- Australia
- Volunteers
- 150 people
- Sponsor
- Sir Charles Gairdner Hospital
Anemia During Pregnancy, Anemia Complicating Pregnancy
Middle Cerebral Artery Doppler( MCA-PSV) & Perinatal Outcome
can we predict neonatal outcome by the results of 3rd trimester MCA Doppler Indices In pregnant women with anemia?? --- the aim of this study is to evaluate values of MCA Doppler indices in determining fetal outcome in pregnant…
- Conditions
- Anemia During Pregnancy, Anemia Complicating Pregnancy, Anemia
- Trial name
- NCT07135635
- Testing
- Middle Cerebral Artery doppler
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Atypical Hemolytic Uremic Syndrome
Eculizumab to Cemdisiran Switch in aHUS
Atypical Hemolytic Uremic Syndrome (aHUS) is a rare, lifethreatening, chronic disease of complement-mediated thrombotic microangiopathy (TMA) characterized by acute onset of renal impairment, thrombocytopenia, and…
- Trial name
- DANCE (NCT03999840)
- Testing
- cemdisiran
- Where
- Italy
- Sponsor
- Mario Negri Institute for Pharmacological Research
Anemia, Chronic Kidney Disease
A Study of Luspatercept in People With Anemia
The researchers are doing this study to test whether luspatercept works to improve hemoglobin levels in people with anemia caused by chronic kidney disease (CKD).
- Trial name
- NCT07725497
- Testing
- Luspatercept
- Where
- 7 sites in United States
- Volunteers
- 30 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Chronic Disease, Kidney Diseases
A Study to Evaluate Whether Correction of Anemia Using Recombinant Human Erythropoietin Reduces the Progression of Atherosclerosis and Cardiac Hypertrophy in Pre-dialysis Chronic Kidney Disease Patients
The primary aim of the study is to evaluate the effects of correction of anemia using erythropoietin on the progression of atherosclerosis and cardiac muscle thickening in patients with chronic kidney disease
- Conditions
- Chronic Disease, Kidney Diseases, Cardiovascular Diseases
- Trial name
- NCT00563355
- Testing
- erythropoietin
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Hospital Authority, Hong Kong
Anemia, Iron Deficiency Anaemia in Childbirth
Impact of Iron Supplementation During Pregnancy
During pregnancy, iron deficiency is the most common cause of anemia. Anemia is very common during pregnancy and after childbirth.
- Conditions
- Anemia, Iron Deficiency Anaemia in Childbirth, Pregnancy
- Trial name
- NCT07814378
- Testing
- Iron
- Where
- 2 sites in Germany
- Volunteers
- 800 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Anemia Ferropenic, Risk of Hemoconcentration (Iron Levels >130g/L)
Effectiveness of Adaptation of the Dose of Iron Supplementation in Pregnancy on Maternal-child Health. (ECLIPSES)
Currently, there is no consensus regarding iron supplementation dose that is most beneficial for maternal and offspring health during gestation. This deficit, or excess, of iron prejudices the mother-child wellbeing.
- Trial name
- (ECLIPSES) (NCT03196882)
- Testing
- 40mg/day of iron, 20mg/day of iron, 80mg/day of iron
- Where
- 2 sites in Spain
- Volunteers
- 704 people, healthy volunteers welcome
- Sponsor
- Victoria Arija Val
Paroxysmal Nocturnal Hemoglobinuria, Hemoglobinuria
Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Subclinical Paroxysmal Nocturnal Hemoglobinuria and PNH in the Setting of Another Bone Marrow Failure Syndromes(PNH-2013)
Paroxysmal nocturnal hemoglobinuria is an acquired chronic hemolytic anemia,this study is designed to evaluate the safety and efficacy of Levamisole combined with cyclosporine A in patients with Subclinical Paroxysmal Nocturnal…
- Conditions
- Paroxysmal Nocturnal Hemoglobinuria, Hemoglobinuria, Hemoglobinuria, Paroxysmal, Proteinuria
- Trial name
- NCT01760096
- Testing
- Levamisole+cyclosporin A+Glucocorticoids, cyclosporin A+Glucocorticoids, Glucocorticoids
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis
A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medications
The primary objective of this study will be to evaluate the drug-drug interaction potential of CCX168 with concomitant medications, as either a perpetrator or a victim, following oral administration of CCX168 to healthy…
- Trial name
- NCT06004947
- Testing
- CCX168, Midazolam, Celecoxib
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Amgen
Anaemia, Chronic Kidney Disease
Probiotics Against Erythropoietin Resistance in Chronic Kidney Disease Patients.
The goal of this clinical trial is to assess whether probiotic supplementation can improve the hematological response of CKD patients to erythropoietin therapy and prevent or reduce erythropoietin resistance.
- Conditions
- Anaemia, Chronic Kidney Disease, Regular Hemodialysis
- Trial name
- NCT07296146
- Testing
- Erythropoietin + Probiotic, EPO
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Badr University