Clinical trials: Anemia in Pregnancy
Stunting, Low Birth Weight
Evidence Generation Related to Stunting Prevention in Balochistan
The World Food Programme (WFP) has signed MoU with Planning and Development Department of Balochistan in collaboration with Nutrition Cell and National Programme for Family Planning and Primary Health Care, Balochistan for the…
- Conditions
- Stunting, Low Birth Weight, Anemia in Pregnancy
- Trial name
- NCT03689218
- Testing
- Maamta (Nutritious Food Supplement), Wawamum (Lipid-Based Nutrient Supplement)
- Where
- 2 sites in Pakistan
- Volunteers
- 2,180 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Anaemia
Study to Assess the Pharmacokinetics of GSK1278863 in Subjects With End Stage Renal Disease Undergoing Peritoneal Dialysis
GSK1278863 is an orally-active, novel small molecule agent which inhibits hypoxia-inducible factor (HIF) prolyl -4- hydroxylases (PHDs) and is in development for the treatment of anaemia associated with chronic kidney disease…
- Trial name
- NCT02243306
- Testing
- GSK1278863
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- GlaxoSmithKline
Pregnancy, Protein-Energy Malnutrition
NutFish and Nutrient Supplementation in Pregnancy Class to Improve Maternal and Birth Outcomes
This study evaluates the intervention of Nut Fish based food, micro nutrients supplementation and pregnancy class to improve maternal and birth outcome. This is cluster randomized trial with two arms.
- Conditions
- Pregnancy, Protein-Energy Malnutrition, Anemia
- Trial name
- NCT02959125
- Testing
- NutFish Based Food Supplementation, Multiple micronutrients, Health Education in Pregnancy Class
- Where
- 2 sites in Indonesia
- Volunteers
- 72 people
- Sponsor
- Semarang Health Polytechnic
Post Partum Hemorrhage, Anemia
Single Dose Intravenous Iron Isomaltoside in Combination With Oral Iron vs Oral Iron Monotherapy in Patients With Anemia After Postpartum Haemorrhage
The investigator's study is going to compare effectiveness of single dose intravenous iron in combination with oral iron versus oral iron monotherapy in correcting haemoglobin deficit, replenishing iron stores and improving…
- Trial name
- IVIronPPH (NCT04505514)
- Testing
- Iron Isomaltoside 1000, Iberet-Folic-500
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- University of Malaya
Treatment of Iron Deficiency Anemia in Pregnancy
Iron Supplementation Using Total Dose Infusion and Oral Routes for Treatment of Iron Deficiency Anemia in Pregnancy
Evaluate the effect of iron supplementation using oral routes in comparison with total dose infusion of low molecular weight iron dextran in iron deficiency anemia during pregnancy.
- Trial name
- NCT02086838
- Testing
- Theragran Hematinic, low molecular weight iron dextran
- Where
- Egypt
- Volunteers
- 212 people
- Sponsor
- Ain Shams University
IgA Nephropathy, Paroxysmal Nocturnal Hemoglobinuria
A Clinical Study to Evaluate the Effect of Food on the Pharmacokinetic Profiles of HRS-5965 Capsules in Healthy Subjects
The study is being conducted to evaluate the effect of food on pharmacokinetics of HRS-5965 capsules after oral administration.
- Trial name
- NCT07035665
- Testing
- HRS-5965 Capsules
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Chengdu Suncadia Medicine Co., Ltd.
PNH
A Phase IIa Study to Assess the Safety, Efficacy, and Pharmacokinetics of Subcutaneously Administered Pegcetacoplan (APL-2) in Subjects With PNH
This is a Phase IIa, open-label, multiple dose, study in patients with PNH who have not received eculizumab (Soliris ®) in the past. A single cohort of subjects is planned for evaluation.
- Trial name
- NCT03593200
- Testing
- Pegcetacoplan
- Where
- 3 sites in Bulgaria, Serbia
- Volunteers
- 4 people
- Sponsor
- Apellis Pharmaceuticals, Inc.
Anemia, Breast Cancer
Assessment of Quality of Life in Patients With Symptomatic Chemotherapy-induced Anaemia
This is a multicenter, international, prospective, observational study of patients who are receiving systemic chemotherapy for solid tumour cancers (breast, colorectal, ovarian, prostate, lung, bladder, endometrial, renal…
- Conditions
- Anemia, Breast Cancer, Cancer, Colorectal Cancer
- Trial name
- NCT01444456
- Where
- 117 sites in Austria, Belgium and 7 more
- Volunteers
- 1,262 people
- Sponsor
- Amgen
Anemia, Chronic Renal Insufficiency
A Dose Conversion Study of Epoetin Alfa in Subjects With the Anemia of Chronic Kidney Disease.
The purpose of this study was to evaluate hemoglobin stability in subjects who had received darbepoetin alfa for a minimum of 3 months prior to study entry who were then converted to epoetin alfa at the same dosing frequency to…
- Trial name
- NCT00495365
- Testing
- Epoetin alfa
- Volunteers
- 8 people
- Sponsor
- Ortho Biotech Products, L.P.
Anaemia
Study to Evaluate the Safety, Efficacy and Pharmacokinetics of GSK1278863 in Japanese Hemodialysis-Dependent Subjects With Anemia Associated With Chronic Kidney Disease
This study aims to characterize the relationship between dose of GSK1278863 and hemoglobin (Hgb) response in hemodialysis-dependent (HDD) subjects with anemia associated with chronic kidney disease (CKD).
- Trial name
- NCT02019719
- Testing
- GSK1278863
- Where
- 21 sites in Japan
- Volunteers
- 97 people
- Sponsor
- GlaxoSmithKline
Atypical Hemolytic Uremic Syndrome
A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS)
This study aims to evaluate the efficacy and safety of crovalimab in pediatric participants with aHUS.
- Trial name
- COMMUTE-p (NCT04958265)
- Testing
- Crovalimab
- Where
- 20 sites in United States, Belgium and 8 more
- Volunteers
- 41 people
- Sponsor
- Hoffmann-La Roche
Anemia, Chronic Kidney Disease
Paricalcitol Effect on Anemia in CKD
Current activated Vitamin D therapies are approved for treating secondary hyperparathyroidism in chronic kidney disease (CKD), and a large body of experimental data in animals confirms the effects of Vitamin D that extend beyond…
- Trial name
- NCT01768351
- Testing
- Paricalcitol, Calcitriol
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Federico II University
Bloody Diarrhea, STEC, Unspecified
Phase 2/3 Study to Evaluate PK, Safety & Efficacy of INM004 in STEC Positive Pediatric Patients for Prevention of HUS
The investigational medicinal product (IMP), INM004, proposes to neutralize the toxin in the bloodstream to prevent the interaction of the Stx with the specific receptor, by means of a polyclonal antibody to be administered upon…
- Conditions
- Bloody Diarrhea, STEC, Unspecified, Hemolytic-Uremic Syndrome, Pediatric Kidney Disease
- Trial name
- NCT04132375
- Testing
- INM004
- Where
- 7 sites in Argentina
- Volunteers
- 11 people
- Sponsor
- Inmunova S.A.
Iron Deficiency, Anemia
A Trial Comparing Ferumoxytol to Iron Sucrose for the Treatment of Iron Deficiency Anemia in Adult Subjects With Chronic Kidney Disease
The purpose of the study is to evaluate the safety and efficacy of intravenous (IV) ferumoxytol compared to IV iron sucrose for the treatment of iron deficiency anemia (IDA) in participants with chronic kidney disease (CKD).
- Conditions
- Iron Deficiency, Anemia, Kidney Disease
- Trial name
- FIRST (NCT01052779)
- Testing
- Ferumoxytol, Iron Sucrose
- Where
- 36 sites in United States, Belgium and 5 more
- Volunteers
- 162 people
- Sponsor
- AMAG Pharmaceuticals, Inc.
Pregnancy
Assessment of the Nutritional Status of Pregnant Women and Optimization of Prenatal Care Services
A national survey in Niger found that women and children are at risk of undernutrition and that many pregnant women don't visit health centers during pregnancy as often as is recommended.
- Trial name
- NCT01832688
- Testing
- Programmatic prenatal care optimization
- Where
- Niger
- Volunteers
- 2,306 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Chronic Renal Failure, Hemodialysis
Efficacy of Intravenous Iron Administration in Hemodialysis Patients
The purpose of this study is to determine whether the frequency of intravenous iron administration has an effect on anemia correction and oxidative stress formation in hemodialysis patients.
- Conditions
- Chronic Renal Failure, Hemodialysis, Renal Anemia, Iron Deficiency Anemia
- Trial name
- NCT00298441
- Testing
- chondroitin sulfate-iron colloid
- Where
- 2 sites in Japan
- Volunteers
- 50 people
- Sponsor
- Kumamoto University
Kidney Disease, Chronic
An Observational Study to Evaluate the Effectiveness of Mircera Treatment for Renal Anemia in Pre-dialysis Participants With Chronic Kideny Disease (CKD)
This observational trial will examine the efficacy and safety of Mircera for renal anemia in participants with stage III-IV CKD in daily clinical practice.
- Trial name
- NCT02547454
- Testing
- Methoxy polyethylene glycol-epoetin beta
- Where
- 12 sites in Slovenia
- Volunteers
- 393 people
- Sponsor
- Hoffmann-La Roche
Anemia, Dialysis-Dependent Chronic Kidney Disease
Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Participants With Dialysis-dependent Chronic Kidney Disease (DD-CKD)
A multicenter, randomized, open-label, active-controlled Phase 3 study for the maintenance treatment of anemia in participants with dialysis-dependent chronic kidney disease (DD-CKD)
- Trial name
- NCT02892149
- Testing
- Vadadustat, Darbepoetin alfa
- Where
- 278 sites in United States, Argentina and 16 more
- Volunteers
- 3,554 people
- Sponsor
- Akebia Therapeutics
Iron-deficiency, Nutritional Deficiency
Iron Status of Women and Young Children in the United States
This analysis describes the distribution of TBI and the prevalence of iron deficiency (ID) and iron deficiency anemia (IDA) among toddlers, non-pregnant women, and pregnant women.
- Trial name
- NHANES (NCT03274726)
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Hypothermia, Anemia
Delayed Cord Clamping in Premature Infants
Delayed cord clamping has been shown to decrease the risk of bleeding in the brain of premature infants. However this procedure is not standard due to concerns that the premature infant will get too cold.
- Trial name
- NCT01018576
- Testing
- Delayed cord clamping
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, Davis