Clinical trials: Anesthesia, Epidural
Labor, Analgesia, Epidural
Effect of Timing on Efficacy of Morphine Analgesia After 2-chloroprocaine Anesthesia
Epidural chloroprocaine is often used in obstetrical anesthesia because of its fast onset and short duration. These properties make it an ideal drug to use for epidural anesthesia in patients undergoing postpartum tubal ligation.
- Trial name
- NCT00487084
- Testing
- Morphine-CP-saline (MCS), saline-2CP-morphine (SCM), saline-lidocaine-morphine (SLM)
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pregnancy
Reliability of Ultrasound Assisted Epidural Analgesia in Obese and Normal Weight Parturients
This study wants to investigate if ultrasound assisted epidural catheter insertion for labor analgesia is easier and safer to the standard epidural technique.
- Trial name
- NCT01438099
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Università degli Studi dell'Insubria
Hypospadias
Effectiveness of Caudal Epidural Block on Intraoperative Blood Loss During Hypospadias Repair
From September 2014 to March 2015, 57 consecutive patients with hypospadias who are candidate for surgery will be enrolled in this randomized clinical trial.
- Trial name
- NCT02752308
- Testing
- Bupivacaine, General anesthesia, Dilute epinephrine injection
- Volunteers
- 60 people
- Sponsor
- Isfahan University of Medical Sciences
Epidural and Spinal Anesthesia for Cesarean Delivery
How Sweet is it? Measurement of Glucose in Epidural and Spinal Fluid
When a woman requires a cesarean section after labour, anesthesia is usually provided by a pre-existing epidural. Occasionally, the epidural does not work. The anesthesiologist then may give a "spinal anesthetic".
- Trial name
- NCT01391702
- Where
- 2 sites in Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cholelithiasis
Comparing Epidural Versus General Anesthesia for LESS Cholecystectomies
This study is a prospective, comparative, controlled, blinded study that will enroll a total of 70 adults that will undergo elective laparoendoscopic single-site incision gallbladder removal.
- Trial name
- NCT03247257
- Testing
- General Anesthesia, Epidural Anesthesia
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Florida Hospital Tampa Bay Division
Epidural Analgesia After Major Open Abdominal Surgery
Evaluation of the Performance of Epidural Analgesia After Major Abdominal Surgery
Epidural analgesia is widely used for the treatment of acute postoperative pain, and currently represents the gold standard after open major abdominal surgery.
- Trial name
- PAPCAM (NCT04912557)
- Testing
- postoperative pain assess
- Where
- France
- Volunteers
- 69 people
- Sponsor
- University Hospital, Toulouse
Anesthesia; Adverse Effect, Spinal and Epidural
Comparative Study Between Bilateral and Unilateral Spinal Anaesthesia
The purpose of this study is to compare unilateral spinal anesthesia using hyperbaric Prilocaine with "classical bilateral spinal anesthesia" using plain Prilocaine according to block characteristics and quality of micturition…
- Trial name
- NCT01877356
- Testing
- bilateral spinal anesthesia, unilateral spinal anesthesia
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- University Hospital, Antwerp
Intubation Skill, Laryngeal Mask Airway Insertion Skill
Evaluation of Learning Curve of Manual Skills in Anesthesia Residents
To determine number of cases need to perform in new anesthesia residents to be proficient in manual skills.
- Conditions
- Intubation Skill, Laryngeal Mask Airway Insertion Skill, Spinal Anesthesia Skill, Epidural Anesthesia Skill
- Trial name
- NCT01236183
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Cerebral Palsy
The Effect of Epidural Analgesia on Intracranial Pressure by Measuring the Optic Nerve Sheath Diameter Using Ultrasound in Pediatric Patients With Cerebral Palsy
Ultrasonography of optic nerve sheath diameter shows a good level of diagnostic accuracy for detecting intracranial hypertension.
- Trial name
- NCT03200951
- Testing
- Bolus group for epidural block, Infusion group for epidural block
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Labor Pain
Effect of Epidural Analgesia on the Parameter ANI During Childbirth
There are many methods used for the assessment of pain in the area of anesthesia including heart rate variability which reflects the influence of the autonomic nervous system on the heart.
- Trial name
- APD-ANI (NCT01505283)
- Testing
- NaCl 0.9%, Sufentanil, lidocaine
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Hopital Foch
Post-dural Puncture Headache, Post-dural Puncture Backache
Long-term Effects of Accidental Dural Puncture in Patients Having Had an Epidural Blood Patch (LEAP)
Accidental dural puncture (ADP) during placement of an epidural catheter for anesthesia and analgesia is a well known complication. Previous studies have found audiometric deterioration following ADP.
- Trial name
- LEAP (NCT02149680)
- Where
- 2 sites in Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Pregnancy, Labour
Minimum Effective Dose (MED) & Epidural Bupivacaine
Local anaesthetics are highly toxic drugs. They can cause toxicity by an absolute overdose, accidental injection in a blood vessel or slow absorption from the area of injection.
- Conditions
- Pregnancy, Labour, Primigravida Labour, Epidural Block
- Trial name
- NCT02116842
- Testing
- 0.1% bupivacaine, 0.075% bupivacaine, 40 µg fentanyl
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Leeds
Colonic Neoplasms
Influence of Epidural Analgesia on Natural Killer Cell (NK) Activity After Colonic Cancer Surgery
Regional anesthesia may decrease the release of endogenous opioids, increase Natural Killer cell (NK) function and decrease development of metastasis.
- Trial name
- NCT02326727
- Testing
- Ropivacaine, Fentanyl, Propofol
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hillel Yaffe Medical Center
Anesthesia, Epidural, Hypotension
Hypotension Prediction Index to Predict Epidural-labor Analgesia Induced Hypotension
The purpose of this pilot trial is to examine the feasibility and ease of use of monitoring by ClearSight in laboring and delivering patients with the intent to compare time-to-treatment of hypotension between conventionally…
- Trial name
- NCT05906368
- Testing
- ClearSight HPI Monitoring system, Standard of Care Blood Pressure Monitoring
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Obesity, Bariatric Surgery
Comparison of Epidural and Intravenous Analgesia in Laparoscopic Sleeve Gastrectomy Patients
This retrospective observational study aimed to compare the effects of epidural analgesia and intravenous analgesia on early postoperative pulmonary function in patients undergoing laparoscopic sleeve gastrectomy.
- Conditions
- Obesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy
- Trial name
- EAvs IV in LSG (NCT07712224)
- Testing
- Epidural analgesia (0.125% bupivacaine/2mcg fentanyl solution), Intravenous analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Pain Following Thoracotomy Surgery
Study of Exparel Versus Epidural for Pain Control After Thoracotomy
Unilateral intercostal nerve blocks provide pain control as effectively as a continuous thoracic epidural, and will a lower incidence of side effects.
- Trial name
- NCT02178553
- Testing
- Epidural, Intercostal Bupivicaine (Exparel)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Mayo Clinic
Post Operative Pain, Cesarean Section
The Effect of Intravenous Infusion of Tramadol-ondansetron on Recovery After Caesarean Section.
It will be a prospective observational cohort study. The investigators will compare post-cesarean section recovery in patients receiving intravenous infusion of tramadol-ondansetron versus epidural catheter with infusion of local…
- Conditions
- Post Operative Pain, Cesarean Section, Tramadol, Postoperative Recovery
- Trial name
- TRON (NCT05879536)
- Testing
- Tramadol-ondansetron continuous infusion, Ropivacaine via epidural catheter
- Where
- Spain
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Fe
Epidural Analgesia, Hospital Follow-up
Obstetrical Analgesia in the Estaing Hospital Maternity. A Prospective Database to Study the Determinants of Labor Pain and the Resulting Maternal Non Satisfaction.
There is a trend to offer personalized care in many medical domains. In the field of labor pain, it appears that maternal satisfaction about care is multifactorial, and that labor pain is only one of its determinants, competing…
- Trial name
- AOMHE (NCT03314571)
- Testing
- analgesia for labor
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Clermont-Ferrand
Epidural Block in Axial Spondyloarthritis
Ultrasound Guided Epidural Block in Axial SPA
Study Design: A randomized, prospective, pilot, controlled trial. Setting: Rheumatology and rehabilitation department Minia University and Sohag University Objectives: To evaluate the effectiveness of caudal epidural injections…
- Trial name
- NCT04143165
- Testing
- Epidural block with lidocaine and triamcinilone
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Sohag University
Anesthesia, Epidural, Analgesia, Epidural
Comparison of Skin - Epidural and Intervertebral Distances in Sitting and Rider Position
Epidural anesthesia/analgesia can be performed under various positions. In this study, the investigators aimed to compare the intervertebral and skin-epidural distances in "the sitting" and "rider" positions with the help of…
- Conditions
- Anesthesia, Epidural, Analgesia, Epidural, Ultrasound Imaging
- Trial name
- NCT05642234
- Testing
- Epidural Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa