Clinical trials: Anesthesia, General
Delayed Emergence From Anesthesia
General Anesthesia Emergence Induced by Methylphenidate
The purpose of this study is to assess whether methylphenidate affects time of emergence from isoflurane general anesthesia. Time to emergence was defined as the time from termination of isoflurane to extubation.
- Trial name
- MPOrtho (NCT02327195)
- Testing
- Methylphenidate HCl
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Nicoleta Stoicea
Squint Anaesthesia
Comparative Study Between Using Combined Propofol Sedation With subTenon's Infusion as Local Anaesthsia to the Eye Versus General Anesthesia for Strabismus Surgery in Adults
in this study investigators compare two type of anesthetic technique for squint surgery in adult patient first is general anesthesia versus local anesthesia using subtenon injection of local anesthetic.
- Trial name
- squint anaesth (NCT07504354)
- Testing
- sedation with subtenon injection of local anesthetic, General Anesthesia (control group)
- Volunteers
- 60 people
- Sponsor
- Sohag University
Surgery, Mechanical Ventilation Complication
Re-Evaluation of the Effects of High PEEP During General Anesthesia For Surgery (REPEAT)
Aiming to understand the isolated impact of high PEEP in patients undergoing mechanical ventilation for general anesthesia for surgery, three appropriately sized international multicentre randomized controlled trials have been…
- Conditions
- Surgery, Mechanical Ventilation Complication, Pulmonary Complication
- Trial name
- REPEAT (NCT03937375)
- Testing
- High PEEP, Low PEEP
- Where
- 3 sites in Germany, Netherlands and 1 more
- Volunteers
- 3,837 people
- Sponsor
- Hospital Israelita Albert Einstein
Hypotension
Propofol vs. Ciprofol for Anesthesia Induction in Frail Elderly Patients
Post-induction hypotension (PIH) is a common and critical complication during general anesthesia, particularly in frail elderly patients whose physiological reserves are significantly diminished.
- Trial name
- NCT07663695
- Testing
- Ciprofol, Propofol
- Where
- China
- Volunteers
- 96 people
- Sponsor
- General Hospital of Ningxia Medical University
Pharyngitis
Combined Effect of Dexamethasone and Paracetamol for Postoperative Sore Throat
The investigators want to evaluate the efficacy of the dexamethasone and paracetamol for the prevention of postoperative sore throat.
- Trial name
- NCT02252419
- Testing
- Dexamethasone, Paracetamol
- Where
- South Korea
- Volunteers
- 242 people
- Sponsor
- Seoul National University Hospital
Post Operative Pain
Combined Supraclavicular Block and General Anesthesia in Pediatric Patients With Chronic Kidney Disease
compare the safety and efficacy of ultrasound-guided supraclavicular block in addition to general anesthesia in pediatric patients undergoing upper limb superficialization of arteriovenous fistula for hemodialysis.
- Trial name
- NCT05580094
- Testing
- general anesthesia only., general anesthesia plus supraclavicular block.
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Assiut University
Atrial Fibrillation (Paroxysmal)
Safety and Efficacy of Conscious Sedation Versus General Anesthesia in Pulsed-Field Ablation for Paroxysmal Atrial Fibrillation
The goal of this clinical trial is to compare the safety and efficacy of conscious sedation and general anesthesia in patients with paroxysmal atrial fibrillation undergoing their first pulsed-field ablation (PFA) procedure.
- Trial name
- SEDATE-PFA (NCT07541339)
- Testing
- conscious sedation, General Anesthesia (control group)
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Beijing Anzhen Hospital
Anesthesia
Automated Control of Mechanical Ventilation During General Anaesthesia
Prospective, bicentric observational study to assess a novel system for automated control of mechanical ventilation (Smart Vent Control, SVC) during general anesthesia.
- Trial name
- AVAS (NCT02644005)
- Testing
- Smart Vent Control
- Where
- 2 sites in Austria, Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Schleswig-Holstein
Propofol Adverse Reaction
The Effect of Propofol Induction Based on Lean Body Weight on the Depth of Anesthesia
Propofol has significant hemodynamic side effects. It is a lipophilic agent and is generally used at a dose of 2-2.5 mg/kg for induction.
- Trial name
- Propofol (NCT06862245)
- Testing
- T received propofol at a dose of 2-2.5 mg/kg based on total body weight, Group L received propofol at 2-2,5mg/kg dose based on le
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Deviated Septum, Opioid Free Anesthesia
Opioid Free Versus Opioid Based General Anesthesia in Septoplasty Under Nociception Level Guidance
Prospactive observational Clinical study
- Trial name
- NCT07786727
- Testing
- OFA
- Where
- Greece
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Perioperative Respiratory Adverse Events, Anesthesia Outcomes
Nasal Decongestant to Reduce Perioperative Adverse Events in Children With Upper Respiratory Track Infections Having Anesthesia.
The goal of this multicentre, double-blind, randomised controlled trial study is to learn if the use of a nasal spray to open the nasal passages and increase airflow before surgery can reduce the occurrence of perioperative…
- Trial name
- NARWHAL (NCT07000877)
- Testing
- Decongestant nasal spray (oxymetazoline hydrochloride (0.05%))
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Telethon Kids Institute
General Anesthesia
Scale for Evaluating Oral and Pharyngolaryngeal Symptoms After General Anesthesia
More than 320 million surgical procedures are performed worldwide each year, and most of these procedures are performed under general anesthesia.
- Trial name
- NCT06755853
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people
- Sponsor
- Nuh Naci Yazgan University
Mitral Regurgitation, Local Anaesthesia
Deep Sedation Instead of General Anaesthesia in Percutaneous Mitral Valve Repair Using the MitraClip® System
Percutaneous mitral valve repair (PMVR) with the MitraClip® system has emerged as a therapeutic alternative to surgical valve repair in patients who are at high risk and unsuitable for surgery.
- Conditions
- Mitral Regurgitation, Local Anaesthesia, Percutaneous Repair
- Trial name
- NCT02023762
- Volunteers
- 21 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Sevoflurane, Propofol
Comparison of Propofol and Sevoflurane as Maintaining Anesthetics During General Anesthesia of Cesarean Section
Sevoflurane and propofol are the most popular drug choices for maintenance of general anaesthesia for caesarean section. However, effects of these two anesthetics on maternal and fetal outcomes after caesarean section haven't…
- Conditions
- Sevoflurane, Propofol, Cesarean Section
- Trial name
- NCT03149588
- Testing
- propofol, sevoflurane
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Tao Zhang
Nausea and Vomiting, Postoperative
The Role Of Laserpuncture For Prevention Of Nausea And Vomiting Post Strabismus Surgery With General Anesthesia In Adult Patients
This study to determine the effectiveness of a combination of pre-surgical laserpuncture with standard anti-emetic therapy for PONV symptoms in adult patients after strabismus surgery under general anesthesia compared to a…
- Trial name
- NCT06302673
- Testing
- Laserpuncture
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Gastric Cancer
Comparative Study on the Effects of Epidural Dexmedetomidine on Heart Rate Variability During General Anesthesia in Patients Undergoing Gastrectomy
The use of epidural dexmedetomidine decreases the anaesthetic requirements and improved postoperative pain. Dexmedetomidine is a potent and highly selective a2-adrenoceptor agonist and has sympatholytic effect.
- Trial name
- NCT01857141
- Testing
- preemptive dexmedetomidine epidural bolus injection(1.5 mcg/kg), normal saline
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Yonsei University
Cesarean Section Complications, Cesarean Section Pain
Insufficient Regional Anesthesia and Conversion to General Anesthesia for Cesarean Section A Qualitative Multicenter Study
Background In Denmark, approximately 20% of all children are born via cesarean section (C-section), making it the most common surgical procedure (also internationally).
- Conditions
- Cesarean Section Complications, Cesarean Section Pain, Regional Anesthesia
- Trial name
- NCT06669156
- Where
- 7 sites in Denmark
- Volunteers
- 21 people
- Sponsor
- Sygehus Lillebaelt
General Anesthesia
Comparison of a Single Use (Ambu aScope) and a Reusable Flexible Optical Scope for Intubation Through a Supraglottic Airway Device (Aura-i)
In patient who are predicted to be difficult to intubate with a standard direct laryngoscope well use flexible optical intubation via a supraglottic airway devise (the Ambu Aura-i).
- Trial name
- NCT02002364
- Testing
- tracheal intubation
- Where
- 2 sites in Denmark, France
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Intraoperative Hypotension, Jugular Veins
Internal Jugular Vein Ultrasound and Acute Kidney Injury After Abdominal Surgery
This observational study aims to learn whether changes in the internal jugular vein during anesthesia induction can help predict low blood pressure and kidney injury after surgery. The main questions it aims to answer are: 1.
- Conditions
- Intraoperative Hypotension, Jugular Veins, Hypotension on Induction, General Anesthesia With Propofol
- Trial name
- PRO-JUGULAR (NCT07638306)
- Testing
- Internal Jugular Vein Ultrasound Assesment
- Where
- Romania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tîrgu Mureș Emergency Clinical County Hospital, Romania
Anesthesia; Functional
Assessment Through Transcutaneous Brain Oximetry (NIRS) of Two Preoxygenation Techniques
Preoxygenation techniques is currently considered a standard of care, but how they influence cerebral oxygenation remains largely unknown.
- Trial name
- NCT04352049
- Testing
- Preoxygenation
- Where
- 2 sites in Spain
- Volunteers
- 53 people
- Sponsor
- Complexo Hospitalario Universitario de A Coruña