Clinical trials: Anesthesia, Inhalation
General Anesthesia, Inhalation; Gas
End Tidal Anesthetic Concentration in Different Anesthesia Techniques Where Depth of Anesthesia Adjusted With Entropy
The aim of this study is to adjust the end tidal inhalation anesthetic concentration by observing the entropy value in patients who will be provided anesthesia maintenance with volatile anesthetics after applying the routine…
- Trial name
- NCT04203290
- Testing
- Bupivacaine, Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul University
Blood Pressure, Hypotension Drug-Induced
Comparison Between Inhalation and Intravenous Induction of Anaesthesia During Interventional Mitral Valve Repair
The induction of anaesthesia is one of the most critical situations for high-risk-patients undergoing interventions surgery. For several reasons, it is crucial to maintain adequate blood pressure and cardiac output during this…
- Trial name
- COMPETENT (NCT04865614)
- Testing
- Etomidate, Sevoflurane
- Where
- Germany
- Volunteers
- 57 people
- Sponsor
- Heidelberg University
Coronary Disease, Coronary Artery Disease
MACBIS50 in Patients Undergoing CAG During Normothermic CPB Phase.
Background: We determined the minimum alveolar concentration (MAC) of sevoflurane for maintaining bispectral index (BIS) below 50 (MACBIS50) in patients undergoing coronary artery bypass grafting during normothermic…
- Trial name
- NCT02711384
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Instituto Dante Pazzanese de Cardiologia
Analgesia
Evaluation of Surgical Stress Index (SSI) During Sevoflurane/Remifentanil Anesthesia
The aim of the present prospective randomized study was to challenge the ability of SSI to detect painful stimulation during sevoflurane - remifentanil anesthesia.
- Trial name
- NCT00791791
- Testing
- standardized pain stimulus
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University Hospital Schleswig-Holstein
Apnea, Cardiopulmonary Resuscitation
Head Positions to Open the Upper Airway
Ventilation during basic life support improves survival in cardiac arrest patients significantly. Unfortunately, this is in contrast to the willingness of potential rescuers to perform mouth-to-mouth ventilation.
- Trial name
- NCT00869648
- Testing
- Extension, Neutral head position, Anaesthesiologist's position
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Anesthesia
Inhaled Sevofluran vs Endovenous Propofol for Colonoscopy
To compare the anesthetic efficacy of the inhalation versus intravenous technique for maintenance of sedation in patients undergoing endoscopy.
- Trial name
- NCT03818048
- Testing
- Propofol, Sevoflurane
- Volunteers
- 32 people
- Sponsor
- Centro Medico Docente la Trinidad
All Adult Patients Undergoing an Otolaryngology Procedure With Inhaled Methoxyflurane as an Adjunct to Topical or Local Anesthesia
Penthrox in Otolaryngology
Our objective is to explore the use of methoxyflurane anesthesia as an adjunct analgesic to local anesthesia during in-office otolaryngology procedures in a prospective pilot study.
- Trial name
- PenthroxOTL (NCT07003880)
- Testing
- Methoxyflurane anesthesia
- Volunteers
- 50 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Atelectasis
Effect of Spontaneous Breathing on Atelectasis During Induction of General Anesthesia in Patients in Infants
spontaneous breathing on occurrence of atelectsis in infants
- Trial name
- NCT03739697
- Testing
- spontaneous breathing
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Anesthesia, Cardiac Disease
High Flow Nasal Oxygen During Sedation
The primary objective of this study is to test the hypothesis that using high flow nasal oxygen improves ventilation during cardiac implantable electronic device procedures performed with conscious sedation.
- Trial name
- NCT03858257
- Testing
- High flow nasal oxygen, Standard oxygenation
- Where
- Canada
- Volunteers
- 129 people
- Sponsor
- University Health Network, Toronto
Solid Tumor (Excluding CNS)
Effect of a Driving Pressure Adjustment Procedure for High-Frequency Jet Ventilation in Patients Undergoing Tumor Thermal Ablation in Interventional Radiology
Tumor thermal ablation under Jet Ventilation is a procedure performed under general anesthesia that enables tumor ablation under radiological imaging guidance.
- Trial name
- Pulmojet 3 (NCT07408375)
- Testing
- High-Frequency Jet Ventilation (HFJV)
- Where
- 7 sites in France
- Volunteers
- 560 people
- Sponsor
- Nantes University Hospital
Colorectal Neoplasms
Anesthetic Technique on Immune Response in Colorectal Cancer
Knowing the fact that the anesthetic substances can alter the immune response during the surgery, the purpose of the study is to evaluate the influence of two general anesthetic techniques - inhalation vs.
- Trial name
- T-IL-Co-ReCa (NCT01902849)
- Testing
- blood sampling for IL measurement
- Where
- Romania
- Volunteers
- 70 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Intraoperative Ventilation
A Comparison of Different Ventilation Strategies in Children Using the Proseal™ Laryngeal Mask Airway
The purpose of this research study is to compare difference between breathing by oneself or with the partial help from an anesthesia machine in children under general anesthesia.
- Trial name
- NCT00966433
- Testing
- Spontaneous ventilation, Pressure support Ventilation, Pressure control ventilation
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Wake Forest University Health Sciences
Cardiovascular Surgical Procedure
Benefits of Total Intravenous Anesthesia Compared With Inhaled Anesthesia in Cardiovascular Surgery
This study compares the difference in proinflammatory markers Interleukin 6 (IL-6), Tumor necrosis factor alpha (TNFα) and cortisol in patients undergoing cardiovascular surgery to asses if there is a benefit of using intravenous…
- Trial name
- NCT03233815
- Testing
- Propofol, Sevoflurane
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Anesthesia, Postoperative Complications
Evaluation of V/Q Mismatch as Predictor of Pulmonary Postoperative Complications in Patients Undergoing Major Surgery
Pulmonary postoperative complications (PPC) are among the main causes of surgical complications affecting both postoperative morbidity and mortality.
- Conditions
- Anesthesia, Postoperative Complications, Mechanical Ventilation Complication
- Trial name
- VQppc (NCT05454917)
- Testing
- Measure of ventilation/perfusion (V/Q) mismatch using Beacon ALPE (Automatic Lung Paramether Estimator)
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- Università degli Studi di Ferrara
Coughing Responses at Tracheal Extubation, Breathing Patterns
Endotracheal Tube Intolerance and Respiratory Airflow Perception
This is a case-control study designed to enroll 224 patients who will undergo tracheal intubation for general anesthesia in the operating rooms of Peking University People's Hospital between July 20, 2026, and October 31, 2026.
- Trial name
- NCT07759284
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Pain
ANI and NoL Index Variations After Standard Nociceptive Stimulus at 0, 50, 25 % of Inhaled N2O in the Anesthetic Mixture
N2O has been used during general anesthesia (GA) for more than 100 years. It is known to have anesthetic agents sparing effect. But small is know on his real analgesic effect during GA.
- Trial name
- NCT02701478
- Testing
- N2O exposure
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Anxiety State, Pediatric ALL
Anxiolytic Effects of Lavender and Orange Oil
The aim of this study is to determine the possible anxiety reducing effects of lavender oil and orange oil on parents with children receiving dental care under sedation during perioperative wait.
- Conditions
- Anxiety State, Pediatric ALL, Dental Anxiety, Oil; Inhalation
- Trial name
- NCT04079309
- Testing
- Lavender/Orange
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara University
Anesthesia; Bariatric Surgery
Automated Closed Loop Propofol Anaesthesia Versus Desflurane Inhalation Anaesthesia In Bariatric Surgery
Complete recovery from anaesthesia is absolutely desirable in the obese patients to avoid postoperative airway, oxygen ventilation or sleep apnea related complications.
- Trial name
- NCT03099616
- Testing
- Propofol, Desflurane
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Dr Nitin Sethi
Brain Health
A Prospective Clinical Study Observed the Effects of Tubeless Anesthesia Method That Preserves Spontaneous Breathing and the Double-lumen Bronchial Intubation on the Brain Health During the Perioperative Period
This project conducts a prospective cohort study. By using multiple questionnaire survey methods such as the Pittsburgh Sleep Quality Index (PSQI) electronic wristband, QOR15, Pain Catastrophizing Scale (PCS), European…
- Trial name
- NCT07721038
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Guangzhou Medical University
Lung Cancer, Neoplasms, Lung
Incidence of Postthoracotomy Pain Following General Anesthesia: A Comparison Between TIVA and Inhalation Anesthesia
The purpose of this study is to evaluate the incidence of postthoracotomy pain between total intravenous anesthesia (TIVA)and inhalation anesthesia after lung surgery.
- Trial name
- NCT00935571
- Testing
- propofol, remifentanil, sevoflurane
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Asan Medical Center