Clinical trials: Anesthesia, Inhalation
Chronic Rhinosinusitis
Total Intravenous Anesthesia (TIVA) vs. Inhaled Anesthesia for Endoscopic Sinus Surgery.
The purpose of this study is to compare total intravenous anesthesia to inhaled anesthesia in endoscopic sinus surgery for chronic sinusitis.
- Trial name
- NCT01214057
- Testing
- Propofol and Remifentanyl, Sevoflurane and Remifentanyl
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- The University of Texas Health Science Center, Houston
Airway Management, Respiration, Artificial
Non-inferiority Trial Between Sotair® Device Attached to Manual Resuscitator Versus Mechanical Ventilation
Effective respiratory ventilation is achieved by moving the right amount of air in and out of the lungs while keeping the pressures at a safe level.
- Trial name
- NCT06117683
- Testing
- ADULT Sotair Device
- Where
- United States
- Volunteers
- 310 people
- Sponsor
- Rhode Island Hospital
Anesthesia
Recovery After Sugammadex(Propofol vs Sevoflurane)
Sugammadex is used to reverse of a neuro-muscular block deep. It has been reported that its administration could induce signs of recovery despite continuation of anesthetic drugs.
- Trial name
- Sugammadex2 (NCT01579851)
- Testing
- Sugammadex
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Hopital Foch
Muscle Relaxation
Effect of Deep Neuromuscular Block (NMB), Inhalation or TIVA on Pneumoperitoneum.
The objective of this study is to compare the value of deep neuromuscular block (NMB) (using rocuronium) in laparoscopy versus high dose opioids (using remifentanil) or 1 minimum alveolar concentration (MAC) inhalation (using…
- Trial name
- TIVA (NCT01930747)
- Testing
- rocuronium, Sevoflurane, remifentanyl
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- AZ Sint-Jan AV
Ophthalmic, Surgery
Comparison of Desflurane Anesthesia Versus TIVA-TCI in Patients Undergoing Ophthalmic Ambulatory Surgery
This is a single-center, randomized, prospective research which aims to investigate the advantages and disadvantages between desflurane balanced anesthesia and TIVA-TCI with propofol in ophthalmic ambulatory surgery, so that to…
- Conditions
- Ophthalmic, Surgery, Anesthesia
- Trial name
- NCT02922660
- Testing
- desflurane, total intravenous anesthesia, inhalation anesthesia
- Where
- China
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Xiaoliang Gan
Anesthesia; Reaction
Endotracheal Intubation With Sevoflurane in Surgical Pediatric Patients
Aim of the study is to compare the optimal time needed for successful tracheal intubation with immediate 8% sevoflurane and incremental sevoflurane induction in surgical pediatric patients undergoing adenotonsillectomy without…
- Trial name
- NCT02429323
- Testing
- Sevoflurane
- Volunteers
- 100 people
- Sponsor
- University of Sulaimani
Ventilation
A Comparison of Different Ventilation Strategies in Infants Using the PLMA™
The purpose of this research study is to compare difference between breathing by oneself or with the partial help from an anesthesia machine in infants under general anesthesia.
- Trial name
- NCT03235817
- Testing
- Spontaneous ventilation, Pressure support ventilation, Pressure control ventilation
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Wake Forest University
Pulmonary Aspiration of Gastric Contents
Comparison of Different Preoperative Fasting Times in Pediatric Patients Undergoing Elective General Anaesthesia
Rationale of this study is to provide an evidence on minimal safe clear fluid fasting duration without the risk of aspiration of gastric contents during elective pediatric procedures under general anesthesia.
- Trial name
- NCT05922072
- Testing
- Nasogastric aspiration for measurement of Residual Gastric Volume, Nasogastric Aspiration for Measurement of Gastric pH
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- King Edward Medical University
Hypoxia, Pars Plana Vitrectomy
Influence of HFNO on Spontaneous Breathing Support in Patients of Different ASA Risk During Moderate Multimodal Analgo-sedation for Pars Plana Vitrectomy
Pars plana vitrectomy is minimally invasive endoscopic procedure which is usually performed in moderate analgo-sedation given by anesthesiologist combined with topical anesthesia and regional eye anesthesia (retrobulbar or…
- Conditions
- Hypoxia, Pars Plana Vitrectomy, Respiratory Complications
- Trial name
- NCT04055077
- Testing
- Low-flow nasal oxygenation (LFNO) ASA I, Low-flow nasal oxygenation (LFNO) ASA II, Low-flow nasal oxygenation (LFNO) ASA III
- Where
- Croatia
- Volunteers
- 176 people
- Sponsor
- University of Split, School of Medicine
Anesthesia
Different Low-flow Sevoflurane Anesthesia Techniques
After reaching 1 MAC level with 4 lt / min fresh gas flow and 2.5% sevoflurane concentration in the initial stage in 35 patients, anesthesia maintenance will be continued with 0.5 lt / min fresh gas flow and 2 -4% sevoflurane…
- Trial name
- NCT04743193
- Testing
- 2.5 %sevoflurane, 8% sevoflurane low flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli Derince Education and Research Hospital
Breast Augmentation, Inhalation Anesthesia
Effects of General Anesthesia on Quality of Recovery After Transaxillary Endoscopic Breast Augmentation
Among aesthetic or cosmetic surgeries, breast augmentation was the most frequently performed and the endoscopic transaxillary approach has become the preferred incision for Asian women.
- Conditions
- Breast Augmentation, Inhalation Anesthesia, Total Intravenous Anesthesia, Quality of Recovery
- Trial name
- NCT04036487
- Testing
- Desflurane, Propofol
- Where
- Taiwan
- Volunteers
- 104 people
- Sponsor
- Chih-Cheng Hung
Intraoperative Complications, Respiratory Complication
Lower Inspiratory Oxygen Fraction for Preoxygenation
During the induction period of general anesthesia, surgical patients are inevitably experienced a short period of apnea for endotracheal intubation or other airway manipulation.
- Conditions
- Intraoperative Complications, Respiratory Complication, Oxygen Toxicity, Oxygen Deficiency
- Trial name
- NCT03665259
- Testing
- Pure oxygen group, Lower oxygen group
- Where
- Taiwan
- Volunteers
- 304 people
- Sponsor
- E-DA Hospital
Anaesthesia, Postoperative Cognitive Function
Xenon Inhalation During Orthopaedic Surgery in Elderly Subjects.
The primary objective was to explore the feasibility of inhaled xenon for sedation in terms of its effect on postoperative cognitive function in elderly, in comparison with the postoperative cognitive function found after IV…
- Trial name
- NCT00192959
- Testing
- Xenon vs propofol
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Anesthesia, Pediatrics
Chocolate or Sevoflurane: Use of Parosmia to Facilitate More Cooperative Inhalation Inductions in Children
Children undergoing surgery and anesthesia are often negatively impacted by anxiety and fear in the preoperative period. Routine inhalational anesthetic induction is a unique aspect of pediatric anesthesia.
- Trial name
- NCT06449157
- Testing
- Inhalation induction with parosmia
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Johns Hopkins University
Anesthesia, General
Clinical Practice of Inhalation Anesthesia With Sevoflurane in China
Until recently, there was a lack of understanding and consensus among Chinese anesthesiologists how they should practice general anesthesia with volatile anesthetics, since there was no standard of inhalation practice.
- Trial name
- NCT01715857
- Where
- 36 sites in China
- Volunteers
- 4,100 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Percutaneous Transhepatic Cholangiography
Total Intravenous Anesthesia in Percutaneous Transhepatic Cholangiography
Percutaneous transhepatic cholangiography is a disturbing procedure for patients. TIVA with short-acting anesthetics such as propofol and remifentanil is characterized by hemodynamic stability and better compilation profile The…
- Trial name
- NCT03103672
- Testing
- Percutaneous transhepatic cholangiography
- Volunteers
- 60 people
- Sponsor
- Inonu University
Morbid Obesity
Laryngeal Masks for Bariatric Surgery
Obese people pose specific problems as far as the management of airway during surgery. The study aims to compare efficacy and safety of two LMA devices.
- Trial name
- NCT01724970
- Testing
- ProSeal, Supreme LMA
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Padova
Prostate Cancer
Effect of Anesthesia on Optic Nerve Sheath Diameter in Patients Undergoing Robot-assisted Laparoscopic Prostatectomy
The purpose of this study was to evaluate the difference between the optic nerve sheath diameter measured during total intravenous anesthesia and the optic nerve sheath diameter measured during inhalation anesthesia in patients…
- Trial name
- NCT03271502
- Testing
- Total intravenous anesthesia, Inhalation anesthesia
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Asan Medical Center
Extubation Success, Extubation Failure
Combined RSBI, TOF, and BIS for Prediction of Extubation Success
This prospective observational study aims to evaluate the predictive value of the combined use of the rapid shallow breathing index, train-of-four ratio, and bispectral index for extubation success after general anesthesia.
- Conditions
- Extubation Success, Extubation Failure, Postoperative Respiratory Complications
- Trial name
- NCT07577453
- Testing
- Combined pre-extubation assessment using RSBI, TOF ratio, and BIS
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital
End-stage Chronic Renal Disease, Severe Acute Kidney Failure
Renal Transplantation and Inhaled Anesthetic Sevoflurane (SEVOREIN)
Renal transplantation is characterized by ischemia-reperfusion lesions in allograft. In a previous study, Julier and al. (Anesthesiology 2003) have demonstrated that sevoflurane reduces glomerular lesions in kidney of patients…
- Conditions
- End-stage Chronic Renal Disease, Severe Acute Kidney Failure, Renal Transplantation
- Trial name
- SévoRein (NCT00337051)
- Testing
- Sevoflurane, Propofol
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Bordeaux