Clinical trials: Anesthesia, Inhalation
Anesthetics, Inhalation, Neuromuscular Blockade
Effect of Rocuronium and Sugammadex Under Sevoflurane and Desflurane Anesthesia in Children
Sugammadex is the first selective relaxant binding agent approved to reverse certain non-depolarizing neuromuscular drugs in patients 2 years old and above.
- Conditions
- Anesthetics, Inhalation, Neuromuscular Blockade, Anesthesia, General
- Trial name
- NCT03795259
- Testing
- Rocuronium, Sugammadex
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people
- Sponsor
- Istanbul University
Anaesthesia, General, Anesthesia, Intravenous
Oxygenation by 100% Oxygen Via High Flow Nasal Cannula in Surgical Patients
Oxygenation with high-flow nasal cannula with 100% oxygen has only been evaluated in a limited number of studies. Although data are convincing it is of importance to evaluate this new concept in our department before implementing…
- Conditions
- Anaesthesia, General, Anesthesia, Intravenous, Ventilation
- Trial name
- NCT02706431
- Testing
- Hyperventilation
- Volunteers
- 31 people
- Sponsor
- Karolinska University Hospital
Obstructive Sleep Apnea
Influence of Different Anesthetic Procedures on Sleep Disorder Breathing
Obstructive sleep apnea (OSA) is a common form of sleep disordered breathing characterized by partial or complete upper airway obstructions during sleep. OSA is associated with major comorbidities and perioperative complications.
- Trial name
- NCT03499132
- Testing
- anesthesia
- Where
- Czechia
- Volunteers
- 90 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
VENTILATION, Capnography
Effects of Capnometry Monitoring in Post Anesthesia Care Unit
There is few information about the best capnometry value in recovery room for intubated awakening patients. Furthermore, capnometry values could influence ventilation applied by nurses on these patients.
- Trial name
- CAPNOSSPI (NCT03370081)
- Testing
- CAPNOGRAPHY
- Where
- France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Bordeaux
Surgery
Difference Between Inhalation Anesthesia and Total Intravenous Anesthesia in Free Flap Surgery
The purpose of this study is to compare the difference between total intravenous anesthesia to inhaled anesthesia in free flap surgery.
- Trial name
- NCT03263078
- Testing
- Propofol, Sevoflurane
- Where
- Taiwan
- Volunteers
- 78 people
- Sponsor
- Taichung Veterans General Hospital
Thoracoscopic Surgery
Preservation of Spontaneous Breathing in Patients Undergoing Thoracoscopic Surgery
the aim of this study is to evaluate the advantages of the non-intubation compared with intubation anesthesia on enhanced recovery after thoracoscopic surgery
- Trial name
- NCT05595096
- Testing
- General anesthesia with preservation of spontaneous breathing
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Zhenjiang First People's Hospital
Postoperative Complications
Total Intravenous Anesthesia and Inhalation Anesthesia
The aim of us is to define the incidence of postoperative complications and recovery time in view of two anesthesia procedures. During the period between 01.01.2016 and 01.01.2017, totally 583 patients were included in the study…
- Trial name
- NCT03187717
- Volunteers
- 583 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
General Anesthesia
Interest of the Induction With Target-controlled Inhalation of Sevoflurane on Spikes Wave Occurrence
Sevoflurane is widely used for induction of anaesthesia. Several studies showed EEG abnormalities during mask induction with sevoflurane.
- Trial name
- SIZE (NCT00775879)
- Testing
- Induction with Sevoflurane
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Bordeaux
Anesthesia and Analgesia
Diaphragmatic Breathing Exercises in Total Knee Arthroplasty Patients
Rationale: While total knee replacements (TKA) are one of the most commonly performed surgical procedures in the United States, this procedure can also be very painful.
- Trial name
- NCT04336579
- Testing
- Diaphragmatic Breathing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Southern California
Healthy Adults, Gynecological Disease
Sevoflurane, Propofol, Postoperative Pain
The impact of anaesthetic method (intravenous vs. inhalational) has been proposed, but not proven in a large-scale study. The researchers aim to provide an investigation that has sufficient power to clarify the potential effect…
- Trial name
- NCT01437462
- Testing
- Sevoflurane, Propofol
- Where
- Finland
- Volunteers
- 168 people
- Sponsor
- Tampere University Hospital
Respiratory Function, Pediatric Anesthesia
Effects of Different Inspiratory:Expiratory Ratios on Respiratory and Recovery Outcomes During Dental Procedures Under General Anesthesia in Pediatric Patients
This observational study aims to evaluate the effects of different inspiratory to expiratory (I:E) ratios (1:2 vs. 1:3) during mechanical ventilation in pediatric patients undergoing dental procedures under general anesthesia.
- Conditions
- Respiratory Function, Pediatric Anesthesia, General Anesthesia
- Trial name
- NCT07323420
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Pulmonary Ventilation
Comparison of Ventilation Tubes Among Anesthetized Pediatrics
To discover whether different types of ventilation breathing tube influence ventilation effect of children/ neonate, the investigators analysis tidal volume, end tidal carbon dioxide, compliance among children and neonate under…
- Trial name
- NCT03822689
- Testing
- Ventilator breathing tube F2220, Ventilator breathing tube F2216, Ventilator breathing tube F1520
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Anesthesia, Surgery
Influence of the End-inspiratory Pause on Mechanical Ventilation.
This study evaluates the influence of two different end-inspiratory pause (EIP) times on respiratory mechanics and arterial gases of surgical patients when ventilated under an open lung approach (OLA) strategy.
- Trial name
- NCT03568786
- Testing
- End-inspiratory pause 10%, End-inspiratory pause 30%
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Spontaneous Breathing, Laryngomicrosurgery
Evaluation of the Feasibility and Safety of Laryngoscopic Microsurgery Under Non-intubation Anesthesia
Nonintubated anesthesia applied in combination with high-flow nasal oxygen (HFNO) is an alternative strategy for laryngeal microsurgery (LMS).
- Conditions
- Spontaneous Breathing, Laryngomicrosurgery, Superior Laryngeal Nerve Block
- Trial name
- NCT05420649
- Testing
- Non-intubated Laryngomicrosurgery
- Where
- Taiwan
- Volunteers
- 49 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Postoperative Cognitive Dysfunction, NEURON SPECIFIC ENOLASE
EFFECT OF ANESTHESİA TECHNIQUES ON POSTOPERATİVE COGNİTİVE DYSFUNCTION FOR MMSE AND NSE LEVEL
The aim of this study is to compare the effects of total intravenous anesthesia and inhalation anesthesia methods on postoperative cognitive dysfunction according to Mini Mental State Examination scores and Neuron Specific…
- Conditions
- Postoperative Cognitive Dysfunction, NEURON SPECIFIC ENOLASE, MINI MENTAL STATE EXAMINATION TEST
- Trial name
- NCT04279132
- Testing
- POSTOPERATIVE COGNITIVE DYSFUNCTION
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Erzincan University
Respiratory Failure, Respiratory Infection
Avoiding Neuromuscular Blockers to Reduce Complications
The goal of this study to evaluate whether eliminating the use of non-depolarizing neuromuscular blocking agents (NMBA) for maintenance of general anesthesia reduces postoperative pulmonary complications in higher risk patients.
- Conditions
- Respiratory Failure, Respiratory Infection, Aspiration Pneumonia, Pneumonitis
- Trial name
- NCT03962725
- Testing
- Neuromuscular Blocking Agents, Anesthetic Adjuncts
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Beth Israel Deaconess Medical Center
Anesthesia
Preoxygenation With Positive Inspiratory Pressure During Induction of Anesthesia
Adults patients scheduled for elective surgery were randomly allocated to receive preoxygenation with spontaneous breathing, positive pressure ventilation (positive inspiratory pressure: 12 cmH2O) without PEEP, and with PEEP…
- Trial name
- PREOX (NCT02313766)
- Testing
- PPV : positive pressure ventilation, PEEP : PPV + PEEP
- Volunteers
- 150 people
- Sponsor
- University Hospital, Caen
Prostate Cancer
A Comparison of Totally Intravenous and Inhalation Anesthesia for Intraocular Pressure During Robot-Assisted Laparoscopic Radical Prostatectomy
Robot-assisted laparoscopic radical prostatectomy (RALRP) has gained popularity during the past decade and has widely replaced conventional open prostatectomy in many institutions due to reduced blood loss, nerve sparing, less…
- Trial name
- NCT01744262
- Testing
- Total intravenous anesthesia, Inhalation Anesthesia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Pediatric Sedation, Radiotherapy
Sevoflurane Insufflation vs Intravenous Sedation for Radiotherapy in Pediatric Patients
aim of this cross-over study is to compare sedation with insufflated sevoflurane and intravenous sedation for pediatric radiotherapy patients
- Conditions
- Pediatric Sedation, Radiotherapy, Inhalation Anesthesia
- Trial name
- NCT04483258
- Testing
- Sedation with sevoflurane insufflation, intravenous sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ankara City Hospital Bilkent
Ventilation
Manual Ventilation Versus Pressure Controlled Mechanical Ventilation in Children
The investigator will compare the feasibility of manual ventilation and pressure-controlled mechanical ventilation during facemask ventilation in children.
- Trial name
- NCT02751047
- Testing
- manual ventilation, Pressure controlled mechanical ventilation
- Where
- South Korea
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital