Clinical trials: Anesthesia, Inhalation
Sore-throat, Dysphonia
No Post Intubation Laryngeal Symptoms
The purpose of the study is to test a novel endotracheal tube support device that reduces pressure of the tube on the voice box for prevention of post intubation laryngeal symptoms including sore throat, change in voice and…
- Conditions
- Sore-throat, Dysphonia, Dysphagia, Intubation Complication
- Trial name
- No-PILS (NCT05383417)
- Testing
- EndoClip
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Respiratory Hypersensitivity, Perioperative Respiratory Adverse Events
Inhaling Penehyclidine to Prevent Perioperative Respiratory Adverse Events in Children at Risk Undergoing Sevoflurane Anesthesia
This randomized controlled study is to evaluate the effectiveness of inhaling penehyclidine hydrochloride in reducing perioperative respiratory adverse events in children at risk undergoing minor elective surgery.
- Conditions
- Respiratory Hypersensitivity, Perioperative Respiratory Adverse Events, Anticholinergics, Inhalation Therapy; Complications
- Trial name
- PEPSI (NCT06624696)
- Testing
- Penehyclidine hydrochloride, Normal Saline
- Where
- 2 sites in China
- Volunteers
- 204 people
- Sponsor
- Sun Yat-sen University
General Anesthetics Toxicity, Postoperative Cognitive Dysfunction
The Influence of Electroacupuncture on Postoperative Agitation of Pediatrics Undergoing Sevoflurane General Anesthesia
Postoperative agitation is a common complication in pediatric anesthesia, with an incidence ranging from 10% to 80%. Common surgical procedures in children include tonsillectomy, adenoidectomy, insidious penis prolongation and…
- Conditions
- General Anesthetics Toxicity, Postoperative Cognitive Dysfunction, Electroacupuncture
- Trial name
- DZDXEQFWQMSHZD (NCT05924854)
- Testing
- electroacupuncture
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Anesthesia
The Effect of Pressure Support Ventilation on Spontaneous Breathing in Anesthetized Subjects
The aim of this prospective study is to determine the effect of pressure support ventilation (PSV) on minute alveolar ventilation (MAV) and end-tidal carbon dioxide (ETCO2) in anesthetized spontaneously breathing subjects by…
- Trial name
- NCT02385305
- Testing
- Pressure support ventilation by anesthesia machine (Apollo, Dräger)
- Sponsor
- Massachusetts General Hospital
Intubation, Endotracheal
Use of the Stethoscope to Confirm Breathing Tube Placement
This study is intended to validate the use of neck auscultation with an electronic stethoscope during intubation to confirm tracheal tube placement.
- Trial name
- NCT00378651
- Testing
- Neck Auscultation
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Emergence Delirium in Pediatric Anesthesia, Pediatric Anesthesia
The Effect of Paedfusor TCI, Eleveld TCI, and Sevoflurane Anesthesia on Postoperative Awakening Agitation in Pediatric Patients
Emergence delirium is a common complication in pediatric patients undergoing general anesthesia. The aim of this study is to investigate the incidence of postoperative awakening delirium and agitation in pediatric patients aged…
- Conditions
- Emergence Delirium in Pediatric Anesthesia, Pediatric Anesthesia, Postoperative Agitations in Pediatric Patients, Postoperative Nausea and Vomiting (PONV)
- Trial name
- NCT07534956
- Testing
- propofol ( Paedfusor Model), propofol (Eleveld Model), Sevofluorane
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Diabetes Mellitus, Type 2, Anesthesia
Investigation of the Evolution of Gastric Emptying by Gastric Ultra Sonography in Patients Treated With GLP-1 Receptor Agonists on a 7 Days Pausing Period.
Glucagon-like-peptide-1 is a hormone released by the gut enteroendocrine cells. Its secretion occurs after each meal to enable production of insulin and inhibits the production of glucagon to lower after meal glycemia.
- Conditions
- Diabetes Mellitus, Type 2, Anesthesia, Pulmonary Aspiration of Gastric Contents
- Trial name
- NCT06388213
- Testing
- Gastric Ultrasonography
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
General Anesthesia, İnhalation Anesthetics
Effects of Anesthesia Type on QoR-40
To compare the effects of total intravenous anesthesia and inhalation anesthesia used for maintenance on postoperative recovery in patients undergoing septorhinoplasty surgery under general anesthesia, using the recovery quality…
- Conditions
- General Anesthesia, İnhalation Anesthetics, Quality of Recovery
- Trial name
- NCT06423313
- Testing
- maintenance of anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Pediatric ALL
Propofol to Reduce the Incidence of Postanesthetic Emergence Agitation in Pediatric Patients Under General Anesthesia
This study aimed to know the effectivity of 0.5 mg/kg propofol in the end of anesthesia to reduce the incidence of postanesthetic emergence agitation in pediatric patients under general inhalation anesthesia
- Trial name
- NCT03528954
- Testing
- Propofol
- Where
- Indonesia
- Volunteers
- 54 people
- Sponsor
- Universitas Indonesia
Desflurane, Anesthesia, General
The Effect of Anthropometrics on Desflurane Rise Time
Desflurane is increasingly used in general anesthesia. Its pharmacokinetic properties are known and its distribution is easily modeled. Yet these models fail in practice.
- Trial name
- NCT06026033
- Testing
- Desflurane induction
- Where
- Turkey (Türkiye)
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
End-stage Lung Disease
BREATHE Study: Spontaneous Breathing-Preserved Anesthesia and Surgical Strategy for Hospital Recovery in Lung Transplantation
The goal of this study is to learn whether a spontaneous-breathing ("tubeless") anesthesia and surgery strategy can improve early recovery and remain safe for adults who receive a lung transplant.
- Trial name
- BREATHE-LTx (NCT07384546)
- Testing
- Lung transplantation that preserves spontaneous breathing function
- Volunteers
- 110 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Children, Hernia, Inguinal
Comparing Inhalation and Total Intravenous Anesthesia Methods
This study compares the effects of anesthesia using target-controlled infusion (TCI) and inhalation methods on pediatric patients undergoing inguinal hernia repair.
- Trial name
- TIVA-IHA (NCT06467279)
- Testing
- Target Controlled İnfusion, Inhalation anesthetic
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Anesthesia
Comparison of Minimal Fresh Gas Requirements of Baby EAR and Jackson Rees Anesthetic Circuit
The investigators invented the baby enclosed afferent reservoir anesthesia circuit (Baby EAR) which could be used safely in children between 5 and 20 kg, using a fresh gas flow of 2.5 and 3 L/min in the spontaneous breathing and…
- Trial name
- NCT02167269
- Testing
- Baby EAR
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Khon Kaen University
Laparoscopic Sleeve Gastrectomy
Total Intravenous Anesthesia Versus Inhalation Anesthesia on Postoperative Liver Function
The pandemic of obesity has become a serious issue of public health worldwide as the size of the obese population has almost tripled over the last four decades and continues to riseزThe epidemic of obesity has led to a…
- Trial name
- NCT06423846
- Testing
- Total intravenous anesthesia group, sevoflurane group
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Benha University
Surgery--Complications, Anesthesia Complication
THRIVE Feasibility Trial
To evaluate the feasibility of a pragmatic, large scale, comparative effectiveness, randomized evaluation of patient experience of intravenous propofol versus inhaled volatile anesthesia.
- Conditions
- Surgery--Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia Emergence Delirium
- Trial name
- THRIVE (NCT05346588)
- Testing
- Anesthetic technique Propofol TIVA, Anesthetic technique inhaled agent
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- Washington University School of Medicine
Chronic Obstructive Airway Disease
Safety and Efficacy of Inhaled Sedation in Management of Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Brief Summary (Plain Language) This study tests whether using a device called AnaConDa® to give a mild gas medicine (isoflurane) helps people with severe flare-ups of chronic obstructive pulmonary disease (COPD) breathe more…
- Trial name
- NCT07191470
- Testing
- The Anaesthetic Conserving Device (AnaConDa)
- Where
- India
- Volunteers
- 10 people
- Sponsor
- Pandit Bhagwat Dayal Sharma, PGIMS, Rohtak
Anesthesia, Inhalation; Vapor
Decreasing Environmental Impact and Costs of Using Inhalational Anesthetic With a Carbon Dioxide Membrane Filter System
Efficient inhalational anesthetic delivery requires the use of low-flow air and oxygen to reduce drug waste and minimize workspace contamination and environmental pollution.
- Trial name
- NCT04210570
- Testing
- Memsorb, Chemical granulate absorber
- Where
- Canada
- Volunteers
- 510 people
- Sponsor
- Western University, Canada
Anesthesia, General
Evaluation of Volatile Induction and Maintenance Anesthesia (VIMA) With Sevorane in Adult Patients Requiring General Anesthesia for Surgery in Terms of Quality of Anesthesia and Its Influence on the Cardiovascular System in Common Clinical Practice
The main objective of this post-marketing observational study (PMOS) is to collect data of using general anesthesia in patients undergoing any surgery to create local recommendations.
- Trial name
- SEVOPROTECTION (NCT01282086)
- Where
- 10 sites in Ukraine
- Volunteers
- 1,365 people
- Sponsor
- Abbott (Ukraine)
Morbid Obesity, Bariatric Surgery Candidate
Anesthetics and Cerebral Oxygenation in LSG
Obesity is a global health issue that affects different organ systems and may cause severe health issues. Patients with a BMI > 40 kg/m2 or those with a BMI > 35 kg/m2 with accompanying comorbidities are candidates for weight…
- Conditions
- Morbid Obesity, Bariatric Surgery Candidate, Anesthesia
- Trial name
- NCT03946657
- Testing
- Inhalational anesthetic, Intravenous anesthetic
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Balanced Anesthesia
Surgical Pleth Index (SPI) Guided Analgesia During Sevoflurane Anesthesia
The aim of the present study was to compare SPI guided analgesia with standard clinical practise during general anesthesia using a balanced setting of sevoflurane and sufentanil anesthesia.
- Trial name
- NCT01525537
- Testing
- administration of sufentanil, sufentanil
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- University Hospital Schleswig-Holstein