Clinical trials: Anesthesia, Intravenous
Hypotension
Interest of Intravenous Ondansetron in the Prevention of Spinal Anaesthesia-induced Hypotension in Caesarean Section
The intravenous injection of 8mg of ondansetron (a serotonin type 3 receptor antagonist) before spinal anaesthesia for caesarean section, leads to a smaller reduction in systolic arterial pressure (SAP).
- Trial name
- ZORA (NCT02862873)
- Testing
- Spinal anaesthesia, Ondansetron, saline solution
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Obesity, Morbid, Anesthesia
Evaluation of Propofol Dosing Based on Total Body Weight Using Closes-loop Anaesthesia Delivery System
The pharmacokinetic profile of various drugs is altered in obese patients especially those administered by the intravenous route.
- Conditions
- Obesity, Morbid, Anesthesia, Propofol
- Trial name
- NCT05305313
- Testing
- Propofol
- Where
- India
- Volunteers
- 46 people
- Sponsor
- Sir Ganga Ram Hospital
Anesthesia Outcomes, Anesthesia Complication
Does Style of Pre-sedation Instructions Improve Patient Outcomes in Ambulatory Anesthesia for Oral and Maxillofacial Surgery?
This randomized controlled trial aims to evaluate the impact of a brief guided visualization exercise on anesthesia-related outcomes in oral and maxillofacial surgery in patients scheduled for ambulatory anesthesia in the oral…
- Conditions
- Anesthesia Outcomes, Anesthesia Complication, Anesthesia and Procedure Related Time Intervals, Anesthesia Recovery Period
- Trial name
- NCT06768021
- Testing
- Guided visualization and standardized pre-sedation instructions, Standardized pre-sedation instructions only
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Alameda Health System
Postoperative Sleep Quality, General Anesthesia
The Effects of Intravenous Anesthetics and Inhaled Anesthetics on Patients' Postoperative Sleep
Adequate sleep is necessary for physical and mental health of human being. Although surgery and anesthesia techniques have improved in resent years, postoperative sleep disturbance remains a challenging problem in surgical…
- Conditions
- Postoperative Sleep Quality, General Anesthesia, Propofol, Sevoflurane
- Trial name
- NCT04123249
- Testing
- Propofol, Sevoflurane
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Yanchao Yang
Balanced Anesthesia, Intracerebral Hemorrhage
Hemodynamics and Vital Organ Function in Intracerebral Hemorrhage
Spontaneous non-traumatic intracerebral hemorrhage (ICH) is a common symptom in clinical practice and is the most serious among all types of stroke.Recently, as a relatively mainstream and recognized INTERACT2 (five well-known…
- Conditions
- Balanced Anesthesia, Intracerebral Hemorrhage, Total Intravenous Anesthesia
- Trial name
- NCT03129009
- Testing
- Total intravenous anesthesia group, Balanced anesthesia group
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xuzhou Medical University
Non Elective Cesarean Section and Ketamine Analgesia
Analgesia Effects of Intravenous Ketamine After Spinal Anesthesia for Non-elective Cesarean Section
This randomized double blind study will be conducted in pregnant woman planned for non elective cesarean section under spinal anesthesia.
- Trial name
- NCT03450499
- Testing
- Ketamine
- Where
- Nepal
- Volunteers
- 80 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Anesthesia, Intravenous
A Study to Assess Placement and Confirmation of Peripheral Inserted Central Catheters Tip Position Using a New Electrocardiographic Method
This is a prospective, single center, observational study. Patients who require a Peripheral Inserted Central Catheters (PICC) will constitute the study population.
- Trial name
- SHERLOCK 3CG (NCT01969981)
- Testing
- PICC placement with Sherlock 3CG
- Where
- France
- Volunteers
- 571 people
- Sponsor
- Centre Leon Berard
Anesthesia
Ultrasound Guided Peripheral IV Insertion
Hypothesis The initial use of ultrasound guidance when indicated for difficult peripheral IV access will reduce the number of attempts required to achieve successful peripheral IV insertion and improve patient care and…
- Trial name
- USGPIV (NCT03841864)
- Testing
- IV placement using ultrasound guidance vs traditional method
- Where
- United States
- Volunteers
- 667 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Anaesthesia
First Administration to Man Of Org 25435 a New Intravenous Anesthetic
Title: First administration to man of Org 25435, a new intravenous anaesthetic. Protocol: 12.4.104 Clinical Phase: Phase I Study Site: Phase I Clinical Trials Unit Ltd Old Convent of Notre Dame 119 Looseleigh Lane Plymouth PL6…
- Trial name
- NCT01062867
- Testing
- ORG25435
- Where
- 2 sites in United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Plymouth
Pain, Postoperative
Usefulness of Lidocaine in Oral and Maxillofacial Surgeries Under General Anesthesia for Pain Control After Operation
This will be a randomized double blinded clinical study conducted in patients undergoing oral and maxillofacial surgery under general anesthesia.
- Trial name
- NCT03479320
- Testing
- Lidocaine
- Where
- Nepal
- Volunteers
- 40 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Anesthesia
Automatic Control of Total Intravenous Anesthesia (ACTIVA)
This study concerns the clinical evaluation of a closed loop control system for the automatic administration of anesthetic drugs in TIVA (Total Intra Venous Anesthesia).
- Trial name
- ACTIVA (NCT04432974)
- Testing
- Automatic closed-loop anesthesia
- Where
- Italy
- Volunteers
- 139 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Immunity Factors in Cancer Colon Patients
Epidural-inhalational Versus Epidural-intravenous Anaesthesia on Anti-tumor Immunity in Patients With Cancer Colon
Surgery is the primary treatment for colon cancer. However, the rate of recurrence or metastasis in colon cancer can be as high as 30%, even in stages 1 and 2 . Most colon cancer-related deaths are caused by metastatic disease .
- Trial name
- tumorimmunity (NCT04518579)
- Testing
- thoracic epidural
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- South Egypt Cancer Institute
Post Spinal Anesthesia Shivering
Clonidine Versus Granisetron for Shivering Prevension
Prevention of post spinal anesthesia shivering during cesarean section with its associated discomfort, distress, aggravation of pain, increased metabolic demands, and increased oxygen consumption
- Trial name
- NCT06031090
- Testing
- Clonidine Injection, Granisetron Injection, Normal Saline 10 mL Injection
- Where
- Egypt
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Analgesia, Patient-Controlled, Epidural Analgesia
Intrathecal Morphine Analgesia vs. Continuous Epidural Analgesia vs. Systemic Analgesia in Colorectal Surgery.
The purpose of this study is to determine which postoperative analgesia is optimal after colorectal surgery. The investigators will compare intrathecal morphine, continuous epidural analgesia and standard systemic analgesia.
- Conditions
- Analgesia, Patient-Controlled, Epidural Analgesia, Anesthesia; Spinal, Morphine
- Trial name
- KOLORIT (NCT03007121)
- Testing
- Morphine intrathecal, Bupivacaine + Sufentanil epidural, Morphine intravenous
- Where
- Czechia
- Volunteers
- 75 people
- Sponsor
- Charles University, Czech Republic
Cholelithiases
Effect of Intravenous Low-Dose Ketamine Infusion With Intravenous Lignocaine Infusion on Post-Operative Pain in Patients Undergoing Laparoscopic Choleysystectomy Under General Anesthesia
Objective: To determine the effect of low-dose ketamine versus lignocaine on post-operative pain in patients undergoing LC under general anesthesia in a tertiary care hospital.
- Trial name
- NCT06964555
- Testing
- Intravenous Ketamine Infusions, Intravenous lignocaine
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Fazaia Ruth Pfau Medical College
Endoscopic Sinus Surgery
PRD-guided Analgesia During FESS for Intraoperative Blood Loss
The aim of this randomized trial is to assess the utility of Pupillary Dilatation Reflex (PRD) for monitoring pain perception intraoperatively and its influence on intraoperative blood loss, quality of surgical field using…
- Trial name
- FESSPRD (NCT03417206)
- Testing
- Remifentanil, pupillary dilatation reflex
- Volunteers
- 120 people
- Sponsor
- Medical University of Silesia
Distal Radius Fracture
Bier's Block Versus Systemic Analgesia
Background: There are three methods for procedural sedation in upper extremity traumas; systemic, regional and local anesthesia. There is controversy in the literature regarding the method of choice for this purpose.
- Trial name
- NCT03349216
- Testing
- Intravenous Regional Anesthesia, Systemic Analgesia
- Where
- Iran
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Emergence Agitation, Remimazolam
Effect of Remimazolam vs Sevoflurane Anesthesia on Incidence of Emergence Agitation and Complications in Children Undergoing Ophthalmic Surgery
As a novel ultra-short-acting benzodiazepines drugs, Remimazolam has been accepted for induction and maintenance of clinical anesthesia.
- Conditions
- Emergence Agitation, Remimazolam, Sevoflurane, Pediatric Ophthalmic Surgery
- Trial name
- NCT05527314
- Testing
- Remimazolam, Sevoflurane, Fentanyl
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
General Anesthesia, Total Intravenous Anesthesia
Predicting Bispectral Index Values by Estimated Effect-site Concentration of Propofol and Remifentanil Displayed on the Target-centered Infusion Pump
The BIS is influenced by multiple parameters, such as age,gender, body weight, height, muscle relaxants, hepatic function, co-administered drugs, surgical stimulation, but is thought to be influenced mainly by propofol and…
- Conditions
- General Anesthesia, Total Intravenous Anesthesia, Bispectral Index Monitoring
- Trial name
- NCT01604226
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center