Clinical trials: Anesthesia, Local
Diabetes Mellitus, Local Anesthesia
Lidocaine + Clonidine for Intraoral Anesthesia in Patients With Diabetes Mellitus Type 2
The purpose of this study is to determine whether 2% lidocaine (L) + clonidine (C) (15 mcg/ml) as a vasoconstrictor achieves efficient (equal or better parameters of intraoral local anesthesia in comparison to 2% lidocaine +…
- Trial name
- LCIOADMT2 (NCT02371759)
- Testing
- L+C maxillary anesthesia, L+C mandibular anesthesia, L+E maxillary anesthesia
- Where
- Serbia
- Volunteers
- 256 people
- Sponsor
- University of Belgrade
Hypothalamic Neoplasms, Pituitary Diseases
The Cardiovascular Changes Associated With Septal Local Anaesthesia
The purpose of this study is to determine the effects on the heart of injecting local anaesthetic into the nose prior to surgery on the pituitary gland?
- Conditions
- Hypothalamic Neoplasms, Pituitary Diseases, Anesthesia, Local
- Trial name
- NCT03137615
- Testing
- Pituitary surgery, local anaesthetic injection
- Volunteers
- 15 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Anesthesia, Local, Shoulder Surgery
The Effect of Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine or Bupivacaine
This study will test the hypothesis that adding dexamethasone significantly prolongs the duration of ropivacaine and bupivacaine analgesia, and that the magnitude of the effect differs among the two local anaesthetics..
- Trial name
- NCT00801138
- Testing
- saline, Dexamethasone, ropivacaine
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- The Cleveland Clinic
Nephrolithiasis, Anesthesia, Local
Over 2000 Epidural Anesthesias for Percutaneous Nephrolithotomy - a Retrospective Analysis
Percutaneous nephrolithotomy (PNL) is a renal lithiasis treatment. It is usually two staged: it begins in the lithotomy position for ureteral catheter placement and retrograde pyelography and, subsequently, an optimal renal…
- Trial name
- NCT02986997
- Where
- Poland
- Volunteers
- 2,000 people
- Sponsor
- Medical University of Warsaw
Local Anesthesia, Analgesia Disorder
Intermediate Cervical Block Under Ultrasound for Thyroid Surgery: Impact on Per and Postoperative Opioid Consumption
The investigators included prospectively 35 patients undergoing an intermediate cervical block under ultrasound (GP1) before a thyroidectomy ,compared to a group of 35 patients without a block (GP2).
- Trial name
- ICPBUS (NCT03107585)
- Testing
- bilateral cervical plexus block
- Where
- Tunisia
- Volunteers
- 70 people
- Sponsor
- University Hospital, Mahdia
Local Anesthesia of the Skin
Fractional Laser Assisted Delivery of Anesthetics III
The purpose of this study is to compare the effect of pretreatment with two different ablative laser modalities, a CO2 laser and an Er:YAG laser, and to assess the role of laser density in fractional laser assisted topical…
- Trial name
- NCT02938286
- Testing
- Fractional CO2 laser, 2.5 mJ, 5% density, Fractional CO2 laser, 2.5 mJ, 15% density, Fractional Er:YAG laser, 9 mJ, 5% density
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Netherlands Institute for Pigment Disorders
Nerve Block, Anesthesia, Local
Sensory Distribution of Lateral Femoral Cutaneous Nerve Block
The purpose of this study is to investigate and describe the anatomical distribution of the sensory outcome following LFCN block (LFCN = lateral femoral cutaneous nerve) in relation to the incisional lines after Total Hip…
- Conditions
- Nerve Block, Anesthesia, Local, Pain, Postoperative, Anatomical Distribution
- Trial name
- NCT02957903
- Testing
- Ropivacaine, Isotonic Saline
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Anesthesia, Local
Serum Bupivacaine Concentration Levels After Injection of Liposomal Bupivacaine Into the Knee
Serum levels of bupivacaine over time after peri-articular injection of a mixture of liposomal bupivacaine and plain bupivacaine during total knee arthroplasty.
- Trial name
- NCT02626559
- Testing
- liposomal bupivacaine/plain bupivacaine peri-articular injection
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Utah
Anesthesia, Local
Changes in Tissue Oxygenation Following Regional Anesthesia
Adequate tissue oxygenation is required for effective white blood cell function and bactericidal activity. Decreased tissue oxygenation is a risk factor for perioperative wound infections.
- Trial name
- NCT01418690
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Nationwide Children's Hospital
Anesthesia, Local
Optimal Volume of Bupivacaine in Adductor Canal Nerve Block
To establish adequate volume of levobupivacaine 0.25% in adductor canal nerve block in unilateral cruciate ligament of the knee reconstruction surgery.
- Trial name
- NCT02557386
- Testing
- Levobupivacaine 5 mL, Levobupivacaine 10 mL, Levobupivacaine 15 mL
- Where
- Chile
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Local Anesthesia
Effect of Sodium Bicarbonate Buffered Lidocaine on the Success of IAN Block of Teeth With Irreversible Pulpitis
Buffering of local anesthetics (alkalinization) has been suggested in achieving pain control. The purpose of this prospective, randomized, double-blind study was to evaluate the effect of adding 0.6 mL 8.4% sodium bicarbonate to…
- Trial name
- NCT02226913
- Testing
- 2% lidocaine with 1:80,000 epinephrine, sodium bicarbonate
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Masoud Saatchi
Aortic Aneurysm, Abdominal, Pain
Efficacy of the Ultrasound-guided Transversus Abdominis Plane Block in Open Aortic Abdominal Aneurysm Repair Surgery
The ETAP study aim to assess the effect of the addition of an ultrasound-guided transversus abdominis plane (TAP) block to a multimodal intravenous analgesia protocol on the postoperative pain control in open surgical repair of…
- Conditions
- Aortic Aneurysm, Abdominal, Pain, Anesthesia, Local
- Trial name
- ETAP (NCT02292667)
- Testing
- TAP block, PCA with Chlorhydrate of Morphine, Acetaminophen
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Anesthesia Local
Comparison of Combined Sciatic(Winnie's) Femoral Nerve Block, and Subarachnoid Block Anesthesia for Lower Limb Surgery
60 ASA grades- I, II or III patients, undergoing lower limb surgeries, will be randomly allocated in 2 groups of 30 patients each.
- Trial name
- NCT02713685
- Testing
- Subarachnoid block, combined Femoral and Sciatic nerve block
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Government Medical College, Haldwani
Prostate Cancer, Local Anesthesia
A Prospective Randomized Trial of Two Different Prostate Biopsy Schemes
The main purpose is to compare the detection rate of 20-core versus 12-core prostate biopsy. The secondary objective is to evaluate pain perception using a validated scale to compare the analgesia provided by the two different…
- Conditions
- Prostate Cancer, Local Anesthesia, Prostate-Specific Antigen/Blood, Biopsy/Methods
- Trial name
- NCT02825225
- Testing
- 20 core-biopsy fragments, Base and apex local anesthesia
- Where
- Brazil
- Volunteers
- 750 people
- Sponsor
- University of Nove de Julho
Hip Fractures, Anesthesia, Local
Shamrock - Ultrasound/MR Image Fusion Guided Lumbar Plexus Block
The main objective is to complete a double-blinded randomized controlled crossover trial of lumbar plexus block with the Shamrock technique guided by ultrasound (US)/magnetic resonance imaging (MRI) image fusion vs.
- Conditions
- Hip Fractures, Anesthesia, Local, Pain, Postoperative
- Trial name
- NCT02718976
- Testing
- Lidocaine-epinephrine added gadoterate meglumine
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Local Anesthesia
Effect of Sodium Bicarbonate Buccal Infiltration on the Success of Inferior Alveolar Nerve Block
The purpose of this prospective, randomized, double blind study was to evaluate the effect of a buccal infiltration of sodium bicarbonate on the anesthetic success of the inferior alveolar nerve block (IANB) in patients with…
- Trial name
- NCT02726737
- Testing
- sodium bicarbonate, Lidocaine, sterile distilled water
- Where
- Iran
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Masoud Saatchi
Regional Anesthesia, Caeserian Section
Continuous Infusion for Pain Relief
SPINAL anesthesia is commonly used for cesarean section, and it has become a popular practice to add opioids to spinal solutions to enhance and prolong intraoperative and postoperative analgesia.
- Conditions
- Regional Anesthesia, Caeserian Section, Local Anesthetic
- Trial name
- NCT02711072
- Testing
- control group, infiltration group
- Volunteers
- 60 people
- Sponsor
- Tunisian Military Hospital
Hip Fractures, Anesthesia Local
Suprasacral Parallel Shift - Ultrasound/MR Image Fusion Guided Lumbosacral Plexus Block
The main objective of the trial is to complete a double-blinded randomized controlled trial with crossover design of a lumbosacral plexus block with the Suprasacral Parallel Shift technique guided by ultrasound/magnetic resonance…
- Conditions
- Hip Fractures, Anesthesia Local, Pain, Perioperative
- Trial name
- NCT02593370
- Testing
- Lidocaine-epinephrine added gadoterate meglumine
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Thomas F. Bendtsen
Spinal Diseases, Local Anesthesia
The Effect of Dexmedetomidine Analgesia and Sedation in Minimally Invasive Spine Surgery Under Local Anesthesia
Evaluate safety and efficacy of dexmedetomidine in minimally invasive spine surgery under local anesthesia sedation.Explore the appropriate concentration of dexmedetomidine, whether or not can reduce the amount of local…
- Trial name
- NCT02535273
- Testing
- Dexmedetomidine, Lidocaine, Low-dose Dexmedetomidine
- Volunteers
- 212 people
- Sponsor
- Tang-Du Hospital
Equally of Delivery Systems of Local Anesthesia in Bronchoscopy
Topical Anesthesia / Bronchoscopy
The primary aim of this study is to compare a simplified single-use product (LMA® MAD Nasal™ Intranasal Mucosal Atomization Device, Teleflex medical, Kernen Germany) for topical nasopharyngeal anesthesia in comparison to a…
- Trial name
- TNA (NCT02237651)
- Testing
- topical anesthesia multi-use device, topical anesthesia Intranasal Mucosal Atomization
- Where
- Germany
- Volunteers
- 252 people
- Sponsor
- Hannover Medical School