Clinical trials: Anesthesia, Local
Regional Anesthesia Techniques in Shoulder Surgery
Effectiveness of Field Block Compared With Interscalene Block in Shoulder Surgery
This study will compare two different types of anesthesia used for shoulder surgery. The first method, called an interscalene block, is commonly performed by anesthesiologists and is effective for pain control but may cause side…
- Trial name
- BLOCK-SHOULDER (NCT07173894)
- Testing
- Shoulder Field Block by Orthopedic Surgeon, Interscalene brachial plexus block and superficial cervical plexus block
- Where
- Israel
- Volunteers
- 64 people
- Sponsor
- Rabin Medical Center
Regional Anesthesia, Burn
The Lateral, Anterior, Medial (LAM) Femoral Cutaneous Block: A Case Series Harborview Medical Center, Seattle, WA
Skin donor sites in patients undergoing split-thickness skin grafting surgeries can be very painful postoperatively. This site is most often the anterolateral thigh, the pain at which location can traditionally be covered by a…
- Conditions
- Regional Anesthesia, Burn, Skin Grafting
- Trial name
- LAM (NCT07221903)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Washington
Pain, Postoperative, Osteoarthritis, Knee
Comparing Local Anesthetic Injections to Nerve Blocks for Pain Control After Total Knee Replacement
Why are we doing this study? People who have knee replacement surgery often feel pain afterward. Doctors use different methods to control this pain.
- Conditions
- Pain, Postoperative, Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Trial name
- LIA-PNB-TKA (NCT07744503)
- Testing
- Continuous Femoral and Sciatic Nerve Block (Ropivacaine), Local Infiltration Analgesia (Ropivacaine, Ketorolac, Epinephrine)
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Christopher Male
Postoperative Pain
A Pain Study Comparing Two Commonly Used Medications to Treat Pain After Bowel Surgery
This research study is testing whether the local anesthetic lidocaine is as effective as ropivacaine for post-operative pain control in continuous thoracic paravertebral nerve blocks.
- Trial name
- NCT02849678
- Testing
- Ropivacaine, Lidocaine
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Jacques E. Chelly
Scalp Nerve Block, Craniotomy Surgery
The Efficacy of Regional Scalp Block in Craniotomy
The objective of this clinical trial is to evaluate the role of scalp nerve block in craniotomy. The primary questions it seeks to answer are: What are the efficacy and safety profiles of scalp nerve block in craniotomy? The…
- Trial name
- NCT06720285
- Testing
- nerve block with 0.5% ropivacaine, General anesthesia and opioids (fentanyl, propofol, rocuronium)
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Airlangga
Postanesthetic Excitement, Cesarean Section
Dexmedetomidine Compared to Ondansetron for Postanaesthetic Shivering in Patients Undergoing a Cesarean Section
Evaluate the efficiency of management with intravenous dexmedetomidine compared to intravenous ondansetron to achieve the disappearance of post-anesthetic shivering in a shorter time in the obstetric patient undergoing cesarean…
- Trial name
- NCT06289335
- Testing
- saline solution
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital Central "Dr. Ignacio Morones Prieto"
Osteoarthritis, Knee
Evaluation of the Effect of Triamcinolone at Different Doses on LIA During TKA
To evaluate the efficacy and safety of different doses of triamcinolone for local infiltration analgesia during total knee replacement
- Trial name
- LIA;TKA (NCT05997238)
- Testing
- without triamcinolone, 20mg triamcinolone, 40mg triamcinolone
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Pain, Postoperative
Comparison of Local Anesthetic Dose in PENG Block Performed in Total Hip Replacement Operations
The investigators research was designed as a single-center, prospective, randomized double-blind study. The patients undergoing total hip replacement surgery in Istanbul University Istanbul Medicine Faculty Department of…
- Trial name
- NCT04900116
- Testing
- Bupivacaine HCl 0.5 % in 20 ML Injection, Bupivacaine HCl 0.25 % in 20 ML Injection, Bupivacaine HCl 0.125 % in 20 ML Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Anxiety, Pain
Mindfulness Intervention on Minimally Invasive Vascular Surgery
The goal of this clinical trial is to learn whether a virtual reality (VR)-based mindfulness intervention can reduce anxiety and pain in adults undergoing minimally invasive surgery for lower-extremity varicose veins under local…
- Conditions
- Anxiety, Pain, Varicose Veins of Lower Limb
- Trial name
- NCT07463638
- Testing
- VR-Based Mindfulness Intervention
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Tongji Hospital
Appendectomy, Laparoscopic, Appendicitis Acute
Effect Of Specimen Extraction Site And Local Anesthesia On Postoperative Pain In Laparoscopic Appendectomy
The aim of this prospective, randomized study is to evaluate the effects of two different specimen extraction sites (periumbilical versus left lower quadrant) and the routine application of port-site local anesthesia infiltration…
- Conditions
- Appendectomy, Laparoscopic, Appendicitis Acute, Pain Management
- Trial name
- NCT07824908
- Testing
- Port-site local anesthesia infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- YUNUS YÜKSEL
Pain
Pain Perception After Tubal Ligation
The purpose of this study is to attempt to determine retrospectively whether there was a statistically significant difference in patient need for postoperative narcotics between two different groups of women who received a…
- Trial name
- NCT01062087
- Testing
- Bupivacaine, Lidocaine
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Pain
Comparison of Physical Versus Visual Distraction in the Reduction of Pain During Local Anesthesia
The purpose of this study is to compare physical versus visual distractions to determine which technique reduces perceived pain better during local anesthesia injections.
- Trial name
- NCT04595721
- Testing
- Hidden object, Stress ball
- Sponsor
- Virginia Commonwealth University
Procedural Pain
A Combined 2% Lidocaine Anesthetic Technique for Mandibular Molar Procedures Without Inferior Alveolar Nerve Block
This prospective single-arm pilot study evaluated the clinical effectiveness of a combined local anesthetic technique using 2% lidocaine with 1:100,000 epinephrine for dental procedures involving mandibular molars.
- Trial name
- NCT07771452
- Testing
- Lidocaine 2% with 1:100 000 epinephrine
- Where
- Afghanistan
- Volunteers
- 60 people
- Sponsor
- Herat University
Anesthesia, Local, Child Behavior
The Effect of Needle-free Injection System on Dental Injection Pain in Children
The aim of this study was to compare paediatric patients' pain perception and behavioural response during dental injection using needle free injection (NF) or traditional injection method (TM) over two consecutive visits.
- Conditions
- Anesthesia, Local, Child Behavior, Pain
- Trial name
- NCT06541925
- Testing
- Injection with the needle-free (NF) system, Injection with the traditional method (TM)
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Marmara University
Prostatic Cancer
Clinical Trial to Examine Individual Pain Tolerance in the Use of Two Anesthetic Techniques to Perform Saturation Prostate Biopsy
To assess the effectiveness of two anesthetic techniques by measuring the pain through visual analog scale (VAS), to obtain saturation prostate biopsies.
- Trial name
- NCT02909049
- Testing
- MIDAZOLAM, MEPIVACAÍNE, FENTANILE
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Complexo Hospitalario Universitario de A Coruña
Pain, Postoperative, Anesthesia, Local
Improving Pain Relief Following Laparoscopic Ventral Hernia Repair
Aim The general aim of this study is to improve post-operative pain and reduce morphine consumption following laparoscopic ventral hernia repair (LVHR).
- Conditions
- Pain, Postoperative, Anesthesia, Local, Hernia, Ventral, Laparoscopy
- Trial name
- NCT02785276
- Testing
- AutoFuser Pain Pump, Ropivacaine, Normal Saline (0.9%)
- Where
- New Zealand
- Sponsor
- University of Auckland, New Zealand
Dental Trauma, Local Anesthesia
Clinical Efficiency of Xanthan Hydrogels Containing Local Anesthetics Encapsulated in Nanostructured Lipid Carries
In a crossover, randomized, placebo-controlled, double-blind study, 40 volunteers will receive the following formulations: hydrogels containing LAs (local anesthetic) - lidocaine and prilocaine (both at 2.5%) encapsulated in CLN…
- Conditions
- Dental Trauma, Local Anesthesia, Oral Cavity Disease
- Trial name
- NCT05912335
- Testing
- Topical anesthetic
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Pacemaker Implantation, Pain
Effect of Local Anesthetic EMLA (Lidocaine 2.5% and Prilocaine 2.5%) Cream and Reduction in Dose, Pain and Intravenous Analgesic During Permanent Pacemaker Implantation
The investigators believe that the local anesthetic EMLA (Lidocaine 2.5% and Prilocaine 2.5%) cream will lessen pain and reduce the need for anesthesia and analgesia, when implanting a permanent pacemaker.
- Trial name
- NCT02016976
- Testing
- EMLA Analgesic Cream, Dormicum 2.5 mg and Pethidine 25 mg
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hillel Yaffe Medical Center
Drug-Resistant Epilepsy, Epilepsy
Ultrasound-Guided Intermediate Cervical Plexus Block for Postoperative Analgesia in Vagus Nerve Stimulation Surgery
This retrospective cohort study evaluated the medical records of adult patients who underwent vagus nerve stimulator (VNS) implantation under general anesthesia for drug-resistant epilepsy at Fırat University Hospital between…
- Conditions
- Drug-Resistant Epilepsy, Epilepsy, Postoperative Pain
- Trial name
- NCT07689617
- Testing
- Ultrasound-guided intermediate cervical plexus block, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Firat University
Nephrectomy, Partial Nephrectomy
Erector Spinae Plane Block (ESPB): in Patients Undergoing Surgery Through a Flank or Anterior Subcostal Incision.
Using a randomized double-blinded study design, the study goal is to evaluate the superiority of Erector Spinae Plane block (ESPB) in the peri-operative pain management of patients undergoing surgery through a flank or anterior…
- Conditions
- Nephrectomy, Partial Nephrectomy, Incision Site Discomfort
- Trial name
- NCT03691935
- Testing
- Ropivacaine, Normal saline
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center