Clinical trials: Anesthesia, Local, open to volunteers
Pain, Procedural Pain
E-MOHS Trial of TENS and Vibration During Local Anesthesia
The E-MOHS Trial is a randomized controlled trial evaluating whether active vibration plus transcutaneous electrical nerve stimulation reduces pain during local anesthetic infiltration in adults undergoing Mohs micrographic…
- Conditions
- Pain, Procedural Pain, Local Anesthesia, Mohs Surgery
- Trial name
- E-MOHS (NCT07852455)
- Testing
- Active Vibration:TENS
- Where
- 3 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Minnesota
Hip Fractures, Arthroplasty, Replacement, Hip
PENG Block + LIA For Endoprosthesis Surgery
The goal of this clinical trial is to learn if a new local anesthesia technique can control pain as well as the standard spinal anesthesia for adults having hip endoprosthesis surgery.
- Conditions
- Hip Fractures, Arthroplasty, Replacement, Hip, Pain, Postoperative, Anesthesia and Analgesia
- Trial name
- PENG 360° (NCT07239817)
- Testing
- Pericapsular Nerve Group Blocks with Local Infiltration Analgesia, spinal anesthesia
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- ASST Gaetano Pini-CTO
Anesthesia, Local
Investigating the Effect of Pericapsular Nerve Group (PENG) Block on Postoperative Pain After Peri-acetabular Osteotomy
The aim of this study is to determine the effect of PENG blockade on postoperative pain after either ropivacaine 5 mg/mL or saline (placebo) in patients undergoing PAO.
- Trial name
- NCT06406010
- Testing
- Ropivacaine 5mg/ml 20ml, Saline 0.9%
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Matias Vested
Anesthesia, Local
Targeted Nerve Injection to the Knee (Nerve to Vastus Medialis): Comparing Two Adductor Canal Block Approaches
This randomized, double-blinded volunteer study compares two ways of performing the adductor canal (AC) nerve block at the mid-thigh to see which approach more reliably numbs the anteromedial knee.
- Trial name
- NCT07444827
- Testing
- Traditional adductor canal block, NVM (nerve to vastus medialis) targeted adductor canal block, Chloroprocaine Injection
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Duke University
Dental Crowding, Dental Occlusion, Traumatic
Exploration of the Utility of Dental-dedicated MRI for Dentistry
This description observational research is comparative in design, that is comparing existing standard clinical dental images, not obtained in this study, to test (i.e., ddMRI) images.
- Conditions
- Dental Crowding, Dental Occlusion, Traumatic, Endodontic Disease, Orthodontic Treatment
- Trial name
- NCT06948162
- Testing
- dental-dedicated MRI (ddMRI)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Molar-Incisor Hypomineralization, Molar-Incisor Hypomineralization (MIH)
Comparison of Computer-Assisted and Conventional Local Anesthesia in Children With Molar-Incisor Hypomineralization
The main questions this study aims to answer are: Does computer-controlled local anesthesia cause less pain and anxiety than conventional local anesthesia in children with molar-incisor hypomineralization (MIH)? Is there a…
- Conditions
- Molar-Incisor Hypomineralization, Molar-Incisor Hypomineralization (MIH), Computer-Controlled Local Anesthesia
- Trial name
- NCT07733011
- Testing
- Computer-Controlled Local Anesthesia, Conventional Local Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Marmara University
Local Anesthesia Infiltration
Efficacy of Facial Massager in Reducing Intra Oral Injection Pain in Pediatric Patients
Abstract Background: Local anesthesia is a primary source of anxiety in pediatric dentistry. Objective: To evaluate if mechanical vibration from a low-cost facial massager reduces pain and anxiety during injections using the Gate…
- Trial name
- NCT07682181
- Testing
- Facial T massager, Topical Benzocaine 20%
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Hospital, India
Pain After Surgery, PSP
Intraoperative Bupivacaine Injection to Reduce Acute and Chronic Pain After TVT/TVT-O Surgery. Randomized Double-Blind Trial
This randomized, double-blind controlled trial will evaluate whether intraoperative injection of bupivacaine at the sling insertion site reduces postoperative pelvic and thigh pain in women undergoing TVT or TVT-O surgery for…
- Conditions
- Pain After Surgery, PSP, Chronic Pain Syndrome, Local Anesthesia Infiltration
- Trial name
- PAIN-TVT (NCT07429019)
- Testing
- Bupivacain (Postoperative)
- Volunteers
- 60 people
- Sponsor
- Hadassah Medical Organization
Local Anesthesia, Dental Implants
Comparison of Anesthetic Efficacy and Safety Between Inferior Alveolar Nerve Block and the Infiltrative Technique for the Treatment of Peri-implant Diseases in Posterior Mandibular Implants
This triple-blind randomized clinical trial aims to compare the anesthetic efficacy and safety of two local anesthesia techniques for the surgical treatment of peri-implantitis in posterior mandibular implants: inferior alveolar…
- Conditions
- Local Anesthesia, Dental Implants, Periimplantitis
- Trial name
- NCT07590037
- Testing
- Comparison of anesthetic efficacy and safety between nerve block and infiltrative technique for periimplantitis surgical treatment in poosterior mandibular implants
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Mohs Micrographic Surgery, Anesthesia, Local
Local Anesthetic Clinical Trial
To compare several local anesthetics when used during dermatological surgery.
- Trial name
- NCT07601750
- Testing
- Lidocaine, Bupivacaine Hydrochloride, Mepivacaine Hydrochloride
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Baylor Research Institute
First Trimester Abortion, Surgical Abortion
The Effect of Music Therapy Under Ultrasound Guided Manual Vacuum Aspiration
Manual vacuum aspiration (MVA) is one of the surgical treatment options for managing early pregnancy loss. When compared to traditional surgical method; MVA is safer, more cost-effective, due to its shorter hospitalisation period…
- Conditions
- First Trimester Abortion, Surgical Abortion, Music Intervention, Local Anesthesia
- Trial name
- NCT04708808
- Testing
- music therapy
- Where
- Hong Kong
- Volunteers
- 176 people
- Sponsor
- Chinese University of Hong Kong
Anesthesia, Local
Comparison of Digital Intraosseous and Manual Intraligamentary Anesthesia in Children
The aim of this study is to compare the effects of digital intraosseous anesthesia and manual intraligamentary anesthesia techniques on pain scores during the restorative treatment of permanent mandibular molars in pediatric…
- Trial name
- NCT07524569
- Testing
- Intraligamentary anaesthesia, Digital Intraosseous Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Anxiety, Fear
AI Avatar Video vs. Tell-Show-Do for Reducing Anxiety and Improving Cooperation in Children During Local Anesthesia
This randomized clinical trial aims to compare two behavior guidance techniques used to reduce anxiety in children during local anesthesia injections in dental treatment.
- Conditions
- Anxiety, Fear, Local Anesthesia, Pediatric Dentistry
- Trial name
- NCT07449884
- Testing
- AI Avatar-Based video, Tell-Show-Do Technique
- Where
- Lebanon
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Virtual Reality, Medical Device
Effect of Virtual Reality on Patient's Comfort During Cardiac Electronic Device Implantation.
The purpose of this study is to assess the effect on patient's comfort of a virtual reality experience during a procedure of cardiac electronic device implantation under local anesthesia.
- Conditions
- Virtual Reality, Medical Device, Local Anesthesia, Pain
- Trial name
- NCT06346132
- Testing
- Virtual reality application
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Schlotterbeck Hervé
Fusion of Spine, Lumbar Region, Anesthesia, Local
Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery
The purpose of this study is to determine if the method for injecting local anesthesia affects patients' pain and opioid usage after surgery.
- Conditions
- Fusion of Spine, Lumbar Region, Anesthesia, Local, Pain, Postoperative, Opioid Use
- Trial name
- NCT06528288
- Testing
- Erector Spinae Plane Block, Subcutaneous Anesthesia
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Massachusetts, Worcester
Surgery, Anesthesia, Local
Effect of Fasting on Patient Outcomes After Wide-Awake, Local Anesthesia-only, No Tourniquet (WALANT) Procedures
The purpose of this study is to determine whether eating solid food prior to undergoing a wide awake local-only no tourniquet (WALANT) procedure reduces anxiety in patients or has any effect on outcomes.
- Conditions
- Surgery, Anesthesia, Local, Fasting
- Trial name
- NCT05819801
- Testing
- Non-fasting, Fasting
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- University of California, Irvine
Molar Incisor Hypomineralization, Anesthesia, Local
Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars
The purpose of this randomized, controlled clinical study is to evaluate if application of 38% SDF increases the efficacy of local anesthesia during operative dentistry on permanent molars affected by molar-incisor hypoplasia…
- Trial name
- NCT05964387
- Testing
- SDF
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Dental Anxiety, Local Anesthesia
Lavender vs Bitter Orange Aromatherapy to Reduce Anxiety and Pain in Pediatric Local Anesthesia
This randomized controlled clinical trial aims to evaluate and compare the effectiveness of lavender essential oil and bitter orange essential oil aromatherapy in reducing dental anxiety and pain in children during the…
- Trial name
- NCT07367594
- Testing
- Lavender essential oil in the inhaler, Bitter Orange essential oil in the inhaler
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- October University for Modern Sciences and Arts
Tooth Extraction, Local Anesthesia
Effect of AV Distraction and Acuapoint Stimulation in Pediatric Extraction on Pain and Anxiety
The aim of this study is to evaluate the effectiveness of audiovisual distraction and acuapoint stimulation on anxiety and pain perception during tooth extraction in children.
- Conditions
- Tooth Extraction, Local Anesthesia, Anxiety, Pain
- Trial name
- AV Acupoint (NCT07371442)
- Testing
- Acualief, Audiovisual, TELL SHOW DO
- Where
- Egypt
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Anesthesia, Local
Split Face Study of the Duration of Local Anesthetics - Fourth Arm
This is a research study to compare how long injectable pain medications (anesthetics) commonly used in dermatologic surgery are effective for.
- Trial name
- NCT06694714
- Testing
- 0.5 ml lidocaine + epinephrine 1:100,000, 1.0 ml lidocaine + epinephrine 1:100,000
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University