Clinical trials: Anesthesia, Obstetric
Cesarean Delivery
An Observational Study Measuring in a Non-invasive Approach the Nociception Level Index and Its Association With Pain and Anxieiy Perception Evaluated by Questionnaires, in Awake Women During Elective Cesarean Delivery Under Spinal Anesthesiaanxiety
The Nociception Level (NOL) Index is a multiparametric, non-invasive monitor that objectively assesses nociception by integrating several autonomic physiological signals.
- Trial name
- NCT07726316
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Michael Grach
Obstetric Anesthesia Problems, Anesthesia Morbidity
Quality of Recovery From Obstetric Anaesthesia - a Multicentre Study
Quality of recovery is an important outcome measure in anaesthesia, whilst there are validated tools for this in surgery and regional anesthesia there are no fully validated tools for obstetrics anaesthesia.
- Conditions
- Obstetric Anesthesia Problems, Anesthesia Morbidity, Quality of Life
- Trial name
- ObsQoR (NCT04192045)
- Testing
- Survey
- Where
- United Kingdom
- Volunteers
- 1,638 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Hearing Loss; Post-Dural Puncture Headache; Cesarean Delivery
Evaluation of Postoperative Hearing Loss After Spinal Anesthesia for Elective Cesarean Section in Pregnant Women
This prospective observational study will evaluate postoperative hearing changes in women undergoing elective cesarean delivery under spinal anesthesia.
- Trial name
- NCT07697651
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Duzce University
Obstetric Anesthesia Problems
Determination of Utility of Intergluteal Cleft as Landmark for Neuraxial Midline in Obstetrics
Our aim is to investigate whether a novel landmark, the groove between the buttocks or the intergluteal cleft, can facilitate the identification of the neuraxial midline in obstetric patients when compared to ultrasound as the…
- Trial name
- CLEFT (NCT05983029)
- Testing
- Intergluteal Cleft, Neuraxial Midline, Horizontal Distance between Vertical Markings
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Anesthesia, Epidural, Analgesia, Epidural
"Compuflo®" in Epidural Space Identification
Recently a computerized injection pump has been programmed with its own mathematical algorithm to measure on a digital display the pressure trend in the form of a continuous curve and it has been connected to an acoustic device…
- Trial name
- NCT03503656
- Testing
- epidural catheter placement
- Volunteers
- 140 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Hypothermia, Anesthesia
Electric Warming Mattress to Prevent IPH During LSCS
This study will demonstrate whether an electric warming mattress can reduce the number of patients who get cold and shiver after elective cesarean section.
- Conditions
- Hypothermia, Anesthesia, Obstetric Anesthesia Problems
- Trial name
- ObsIPH (NCT01054209)
- Testing
- Warming with warming mattress
- Where
- United Kingdom
- Volunteers
- 116 people
- Sponsor
- Brighton and Sussex University Hospitals NHS Trust
Post-Dural Puncture Headache, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Predictive Value of ONSD and NIRS for PDPH
Currently, there is no reliable and effective method available in clinical practice to predict the development of PDPH. Early prediction and prevention of PDPH would reduce the incidence of postoperative complications, thereby…
- Trial name
- NCT07729449
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ordu University
Epidural, Labor Pain
Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour
Labour pain can be intensified for labour inductions and women undergoing inductions often have earlier and more frequent requests for analgesia.
- Conditions
- Epidural, Labor Pain, Induction of Labor Affected Fetus / Newborn, Obstetric Anesthesia Problems
- Trial name
- NCT04011098
- Testing
- Epidural Fentanyl Bolus, Standard Epidural Group
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Labour Analgesia
Prediction of Local Anaesthetic Dosing During Labour Epidural Analgesia
Epidural analgesia is the gold standard for controlling labour pain. However, labour pain happens during neuraxial analgesia, due to anaesthetic, obstetric, maternal factors.
- Trial name
- DIANA (NCT07614516)
- Testing
- Machine-learning prediction model
- Where
- Italy
- Volunteers
- 12,500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Gestational Diabetes Mellitus (GDM), Obstetric Anesthesia
ULTRASOUND ASSESSMENT OF GASTRİC VOLUME IN PREGNANT WOMEN UNDERGOİNG ELECTİVE CESAREAN SECTİON, WITH AND WITHOUT GESTATİONAL DIABETES MELLITUS
THE PRIMARY OBJECTIVE OF THIS STUDY IS TO COMPARE GASTRIC VOLUME PRIOR TO ELECTIVE CESAREAN SECTION BETWEEN PREGNANT WOMEN DIAGNOSED WITH GESTATIONAL DIABETES MELLITUS (GDM) AND THOSE WITHOUT GDM.
- Trial name
- GDM (NCT07816705)
- Testing
- GASTRIC ULTRASONOGRAPHY
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital
Labour Analgesia, Epidural Anaesthesia, Duration of Labour
Impact of Timing of Neuraxial Analgesia on Obstetric, Anesthesiologic and Neonatal Outcomes in Induced Labour
The aim of this observational study is to assess the effect of early labour analgesia on obstetric and neonatal outcomes in induced labour in primiparous women with a full-term pregnancy whose labour was induced with a Cook…
- Conditions
- Labour Analgesia, Epidural Anaesthesia, Duration of Labour, Labor, Induced
- Trial name
- TAIL (NCT06886555)
- Testing
- Epidural analgesia for labour pain
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Headache
Mirtazapine vs Sumatriptan in the Treatment of Postdural Puncture Headache
Postdural puncture headache (PDPH) is a potential complication after spinal anesthesia caused by traction on pain-sensitive structures from low cerebrospinal fluid pressure (intracranial hypotension) following a leak of…
- Trial name
- NCT05108688
- Testing
- Mirtazapine, Sumatriptan
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Ain Shams University
Obstetric Pain, Analgesia
Study Comparing Dural Puncture Epidural With Epidural and Combined Spinal Epidural Anesthesia for Obstetric Analgesia.
This will be a prospective, randomized, double blind, controlled clinical trial. Epidural analgesia (EP) is currently the method of choice to ensure the comfort of the parturient during childbirth.
- Trial name
- NCT05196256
- Testing
- Dural puncture, Combined spinal epidural analgesia, Epidural analgesia
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- Brugmann University Hospital
Premature Birth
Balanced Anesthesia for Intubation of Premature Infants
The study aim is to compare a balanced anesthesia of the medicines used in all other age groups with the routine premedication in use for premature's with regards to the success in the intubation procedure, the need for analgesia…
- Trial name
- NCT00216944
- Testing
- Tracheal intubation for respiratory care in preterm infants
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Lund University Hospital
Postpartum Hemorrhage, Cesarean Section Complications
Tranexamic Acid in Patients for Caesarian Delivery.
This is a prospective, double-blinded, randomized placebo-controlled trial. The study will be approved by the DUHS institutional review board (IRB) and the trial will be registered at clinical trial registry.
- Conditions
- Postpartum Hemorrhage, Cesarean Section Complications, Obstetric Anesthesia Problems
- Trial name
- TXA; CD (NCT05759156)
- Testing
- Tranexamic acid injection
- Where
- Pakistan
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Cesarean Section (MeSH: D002585), Anesthesia, Spinal (MeSH: D000775)
Ultrasound Versus Palpation for Determining Spinal Puncture Level in Cesarean Section
This study compares two methods of identifying the correct intervertebral level before performing spinal anesthesia in women undergoing elective cesarean delivery.
- Conditions
- Cesarean Section (MeSH: D002585), Anesthesia, Spinal (MeSH: D000775), Hypotension (MeSH: D007022)
- Trial name
- USG-SPINE (NCT07789756)
- Testing
- Preprocedural ultrasound level identification, Landmark palpation level identification
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Central Nervous System Infections, Pseudotumor Cerebri
A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs Control
This study will compare the VerTouch device to the conventional palpation technique for performing diagnostic and therapeutic neuraxial procedures.
- Conditions
- Central Nervous System Infections, Pseudotumor Cerebri, Neurological Disorder, Cancer
- Trial name
- NCT04796935
- Testing
- Tactile Imaging (VerTouch), Control (palpation)
- Where
- 3 sites in United States
- Volunteers
- 95 people
- Sponsor
- IntuiTap Medical, Inc
Obstetric Anesthesia, Cardiac Monitoring
Cardiac Output Changes With Uterine Displacement
There is currently little information regarding the hemodynamic differences in uterine displacement techniques. Previous studies examining the hemodynamic effects of uterine displacement maneuvers have focused on incidence of…
- Trial name
- LUDCO (NCT02283931)
- Testing
- TTE / NICOM
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Hypotension, Spinal Anesthesia
Pupillary Light Reflex to Predict Post-Spinal Hypotension in Elective Cesarean Delivery
This prospective observational cohort study investigates whether pre-anesthetic pupillary light reflex (PLR) parameters can predict the risk of hypotension following spinal anesthesia in women undergoing elective cesarean…
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Delivery
- Trial name
- NCT07678723
- Testing
- Not applicable- observational study
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Preterm Infant, Anesthesia
The Comparison of Laryngeal Mask Airway and Endotracheal Tube in General Anesthesia for Premature Neonates
Objectives: To compare the perioperative respiratory adverse events between using laryngeal mask airway and endotracheal tube in preterm neonates receiving general anesthesia for hernia surgery.
- Conditions
- Preterm Infant, Anesthesia, Respiratory Complication
- Trial name
- NCT03931902
- Testing
- intubation with Endotracheal tube, intubation with laryngeal mask airway
- Where
- Taiwan
- Volunteers
- 43 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital