Clinical trials: Anesthesia, Recovery
Fracture of Ankle
Analgesic Benefits of Perineural Versus Intravenous Dexamethasone in Patients Receiving Sciatic Nerve Block
Patients scheduled to have foot and ankle surgery will typically receive a single shot sciatic nerve block to serve as the primary anesthetic and as part of a multi-modal post-operative analgesic plan.
- Trial name
- NCT01616173
- Testing
- Dexamethasone, Saline
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwestern University
Hip Arthroplasty, Total, Post Operative Pain, Acute
Supra Inguinal Fascia Iliaca Block as Rescue Analgesia Following Total Hip Arthroplasty
Hip replacement surgery is one of the most commonly performed surgical procedures in France, with approximately 150,000 procedures per year.
- Conditions
- Hip Arthroplasty, Total, Post Operative Pain, Acute, Nerve Block
- Trial name
- SOSBIFSI (NCT06982625)
- Testing
- Ultrasound guided supra inguinal fascia iliaca block, Surgical and anesthetic protocol
- Where
- France
- Volunteers
- 310 people
- Sponsor
- Institut Mutualiste Montsouris
Surgery, Anesthesia
A Study of the Effect of Arterial Carbon Dioxide Tension on the Recovery of Spontaneous Respiration
The investigators data reveal an important new observation regarding the recovery of breathing during emergence from general anesthesia: respiration resumes as a prolonged abdominal expiration event.
- Trial name
- RIP03 (NCT01733446)
- Testing
- Continuation of High Frequency Jet Ventilation (HFJV)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
ADHD - Attention Deficit Disorder With Hyperactivity
Clinical Study of Non-invasive 40-Hz Audiovisual Stimulation Guided by Gamma EEG Monitoring for Promoting Perioperative Brain Function Recovery in Children
Exposure to general anesthesia during early brain development has emerged as an important risk factor for long-term attention-deficit/hyperactivity disorder (ADHD)-like behaviors and learning difficulties in school-aged children.
- Trial name
- NCT07719465
- Testing
- 40-Hz non-invasive synchronized audiovisual stimulation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Anesthesia
Administration of Dexmedetomidine Guided by Entropy/SPI Reduce
Dexmedetomidine, a selective alpha2-adrenergic agonist is known to reduce propofol and opioid requirements due to its sedative and analgesic properties.
- Trial name
- NCT02818621
- Testing
- Group Dex (dexmedetomidine)
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Gangnam Severance Hospital
Humans, Reproducibility of Results
Spanish Validation and Cross-cultural Adaptation of the QoR-15E
The satisfactory recovery of the patient after a surgery with an anesthetic request is very important for a quality and excellence assistance.
- Conditions
- Humans, Reproducibility of Results, Cross-Cultural Comparison, Surveys and Questionnaires
- Trial name
- NCT04699500
- Where
- Spain
- Volunteers
- 242 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Anesthesia Recovery Period, Postoperative Complications
The Anesthesia Effects of Dexmedetomidine Combined With Desflurane or Propofol in Lobectomy
In one-lung ventilation surgery, compared with dexmedetomidine combined with propofol, dexmedetomidine combined with desflurane may be beneficial to accelerate patients' recovery and reduce postoperative pulmonary complications…
- Trial name
- NCT06207344
- Testing
- Dexmedetomidine and propofol, Dexmedetomidine and desflurane
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Preoperative Biliary Drainage, Recovery Period, Anesthesia
Do Preoperative Bilirubin Levels Affect Recovery and Hospital Stay After Sedation Anesthesia?
There are still complexities regarding the effects of anesthetic drugs on bilirubin metabolism. The aim of the study was to investigate whether preoperative serum bilirubin levels are associated with the length of hospital stay…
- Conditions
- Preoperative Biliary Drainage, Recovery Period, Anesthesia, Hospital Length of Stay
- Trial name
- NCT06849661
- Where
- Turkey (Türkiye)
- Volunteers
- 360 people
- Sponsor
- Naime Yalçın
Pain, Postoperative, Anesthesia
Transversus Abdominal Plane Block at Total Laparoscopic Hysterectomy: Effect on Quality of Recovery
The Transversus Abdominal Plane (TAP) block has been used with good success to decrease postoperative pain following laparatomy.
- Trial name
- TAP (NCT01479270)
- Testing
- TAP Block
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Anesthesia, ERAS
Impact of General Anesthesia v/s Spinal Anesthesia on ERAS Parameters in Intestinal Stoma Reversal
Randomized, Interventional ,Open labeled, Parallel Assignment and Superiority trial.
- Conditions
- Anesthesia, ERAS, Surgical Stomas, Ileostomy - Stoma
- Trial name
- SPIGERAS (NCT06226753)
- Testing
- Type of anaesthesia used
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
ObsQor-10, Cesarean Section
Effect of Preoperative Oral Carbohydrate Drink on ObsQoR-10 Score After Elective Cesarean Under Neuraxial Anesthesia
The goal of this clinical trial is to determine whether a preoperative oral carbohydrate-rich clear drink can improve recovery in women undergoing elective cesarean section under neuraxial anesthesia.
- Conditions
- ObsQor-10, Cesarean Section, Preoperative Fasting
- Trial name
- NCT07204795
- Testing
- Distilled water group, Carbohydrate Drink
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Post-induction Hypotension, Post Anesthesia Recovery
Intraoperative Hypotension and Post-anesthesia Care Unit Recovery
The underlying causative mechanism that leads to intraoperative hypotension (IOH) may vary depending on the stage of anesthesia and surgery, which determines different IOH types.
- Conditions
- Post-induction Hypotension, Post Anesthesia Recovery, Hypotension, Intraoperative Hypotension
- Trial name
- NCT05671783
- Testing
- Hemodynamic observation of the patients.
- Where
- Turkey (Türkiye)
- Volunteers
- 4,776 people
- Sponsor
- Acibadem University
Quality Improvement, Quality of Recovery From Anaesthesia
The Impact of Fasting Duration on Quality of Recovery After Cesarean Section
This study will evaluate the effect of fasting duration and elective c-section start time on the overall quality of recovery. Patients will be seen 24 hours after surgery to answer 11 questions on their overall recovery after…
- Conditions
- Quality Improvement, Quality of Recovery From Anaesthesia, Cesarean Section, Fasting ( 6H for Solid ; 2H for Clear Fluid )
- Trial name
- NCT06701929
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Jewish General Hospital
Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum
Anterior Ethmoidal Nerve Block in Prevention of Postoperative Agitation
Postoperative agitation is an important complication of general anesthesia, moreover, it has been found with high incidence in ear, nose, throat (ENT) surgeries.
- Conditions
- Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum, Chronic Rhinosinusitis (Diagnosis), Nasal Polyps
- Trial name
- NCT03427502
- Testing
- Bupivacaine-epinephrine, normal saline
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- Lumbini Medical College
Insomnia
Insomnia and Wake up and Recovery From Anesthesia
18-55 years old 100 patients, who are planned to undergo for planned ureteroscopy will be participated in the study. In the preoperative room patients will be asked to participate to the study.
- Trial name
- NCT04119531
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Adana City Training and Research Hospital
Colon Cancer, Rectal Cancer
Trial Comparing Transversus Abdominis Plane Block Versus Epidural Anesthesia for Pain Management in Colorectal Surgery
The primary outcome for this study is the Numeric Pain Score (NPS) for elective patients undergoing elective colorectal surgery that have been randomized to transversus abdominis plane block or epidural anesthesia for the…
- Conditions
- Colon Cancer, Rectal Cancer, Colonic Diverticulosis
- Trial name
- TAP (NCT02591407)
- Testing
- TAP Block, Continuous Epidural Analgesia
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Trinity Health Michigan
Emergency Abdominal Surgery, Opioid Sparing Anaesthesia
Effect of Opioid-sparing Anesthesia on Quality of Recovery After Emergency Laparotomy
Opioids are widely used during anesthesia for pain control, but they cause many side effects-such as nausea, constipation, respiratory depression, dependence, and delayed recovery.
- Trial name
- NCT07262242
- Testing
- Lidocaine (drug), Fentanyl (IV)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Laryngeal Disease, Pharyngeal Diseases
Comparison of Remimazolam and Propofol for Recovery of Ambulatory Upper Airway Surgery
The purpose of this study is to compare the effects of remimazolam and propofol on postoperative recovery time, complications, and safety in patients undergoing ambulatory upper airway surgery under general anesthesia.
- Conditions
- Laryngeal Disease, Pharyngeal Diseases, Oral Cavity Disease, Nasal Disease
- Trial name
- NCT06507202
- Testing
- Remimazolam, Propofol
- Where
- South Korea
- Volunteers
- 116 people
- Sponsor
- Chung-Ang University Gwangmyeong Hospital
Total Knee Arthroplasty, Regional Anesthesia
Effects of 10 Versus 20 mL Local Anesthetic for Popliteal Plexus Block on Opioid Consumption, Pain, and Patient-Reported Outcomes After Total Knee Arthroplasty
This trial aims to assess the analgesic effect of Popliteal Plexus Block (PPB) with 10 mL versus 20 mL of Bupivacain 5 mg/mL, when applied as an adjunct treatment to a multimodal analgesic regimen following primary total knee…
- Conditions
- Total Knee Arthroplasty, Regional Anesthesia, Multimodal Analgesic Approach, Postoperative Opioid-related Complications
- Trial name
- NCT06908837
- Testing
- Bupivacaine
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Regionshospitalet Silkeborg
Breast Cancer, Postoperative Pain, Acute
Effect of Continuous Erector Spinae Plane Block With Ropivacaine on Postoperative Pain and NF-κB Levels After Mastectomy
This study aims to evaluate the effect of continuous erector spinae plane block (CESPB) using ropivacaine on postoperative pain in patients undergoing elective mastectomy.
- Trial name
- NCT07562945
- Testing
- Continuous Erector Spinae Plane Block, Ropivacaine
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Aldy Aldy