Clinical trials: Anesthesia, Recovery
Postoperative Complications
4-choice Reaction Time Test for the Measurement of Psychomotor Recovery After General Anaesthesia
The recovery of patients after general anaesthesia is usually estimated by using clinical signs and scores. Since there is a lack of the agreed objective methods for assessing cognitive and psychomotor recovery after general…
- Trial name
- 4CRT_Ane (NCT03697057)
- Testing
- General anaesthesia
- Where
- Germany
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Ankle Surgery
Quality of Recovery at Days 5-7 After Ankle Surgery: a Multicenter Study in Seine-Maritime
Ankle fractures are among the most common fractures in trauma care, with an estimated annual incidence of 100 to 150 per 100,000 inhabitants and a marked increase after age 40.
- Trial name
- QoR - CHEVILLE (NCT07814937)
- Testing
- Assessment of recovery quality on days 5-7 after ankle surgery
- Where
- 4 sites in France
- Volunteers
- 260 people
- Sponsor
- University Hospital, Rouen
Analgesia, Postoperative Pain, Acute
Effects of Pericapsular Nerve Group Block on Postoperative Recovery for Total Hip Arthroplasty
The hypothesis of this study is that patients who undergo PENG block in before Total Hip Artroplasthy (THA) surgery with spinal anesthesia will have reduced postoperative pain scores, less need for opioid analgesics and earlier…
- Trial name
- NCT06183528
- Testing
- Pericapsular Nerve Group (PENG) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Umraniye Education and Research Hospital
Anesthesia
Quadratus Lumborum Versus Transversus Abdominis Plane Nerve Block: A Comparison Study
The Transversus Abdominis Plane (TAP) block is the current standard of care for patients undergoing laparoscopic abdominal surgeries with the Enhanced Recovery After Surgery (ERAS) Protocol.
- Trial name
- NCT03490357
- Testing
- Control - Transversus Abdominus Plane Block, Quadratus Lumborum Block
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Postoperative Pain Management in Total Knee Arthroplasty
Dexmedetomidine as an Adjunct to Periarticular Ropivacaine in Total Knee Replacement: A Pilot Randomised Controlled Trial
This study aims to evaluate whether adding dexmedetomidine to ropivacaine-based periarticular infiltration (PAI) improves postoperative pain control in patients undergoing total knee replacement (TKR).
- Trial name
- NCT07176065
- Testing
- Ropivacaine + saline solution, Ropivacaine + Dexmedetomidine
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- University of Malaya
Neuromuscular Blockade
Deep Neuromuscular Blockade During Robotic Radical Prostatectomy
Basic requirement for safe performance of the robotic intra-abdominal surgery is a calm and clear surgical field after the introduction of a capnoperitoneum. That can be enabled by a neuromuscular blockade.
- Trial name
- NCT02513693
- Testing
- Standard neuromuscular blockade, Deep neuromuscular blockade
- Where
- 2 sites in Czechia
- Volunteers
- 80 people
- Sponsor
- Palacky University
Anesthesia
Desflurane and Sevoflurane Minimal Flow Anesthesia on Recovery and Anesthetic Depth
Minimal flow anesthesia has economic and environmental advantages in addition to providing earlier recovery following general anesthesia.
- Trial name
- NCT05024084
- Testing
- Minimal flow anesthesia (fresh gas flow <0.5 l/min) using Sevoflurane, Minimal flow anesthesia (fresh gas flow <0.5 l/min) using Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Ufuk University
Best Technique for Pediatric Anesthesia
Recovery of TIVA vs Inhalation in Pediatric Anesthesia
Compare recovery profile from TIVA and that of total inhalational anesthesia in ambulatory pediatric tonsillectomy and which strategy is more safe and less cost and more smooth in pediatric anesthesia.
- Trial name
- NCT06215833
- Testing
- Propofol, Sevoflurane
- Volunteers
- 120 people
- Sponsor
- Assiut University
Anesthesia, Local
Effect of the Transmuscular Quadratus Lumborum Block on Duration of Stay in Recovery
The study will review data collected in 5 previously completed randomised controlled trials with a new primary outcome: to assess whether administration of the transmuscular quadratus lumborum block has an impact on the time an…
- Trial name
- TQL_PACU (NCT04951752)
- Testing
- Ropivacaine injection
- Where
- Denmark
- Volunteers
- 307 people
- Sponsor
- Zealand University Hospital
Systemic Inflammatory Response Syndrome
Can Biomarkers Aid in the Prediction of Postoperative Pain and Circulatory Instability After Major Abdominal Surgery?
Patients undergoing major surgery are exposed to extensive damage of tissues, which induces widespread activation of the inflammatory system, called 'systemic inflammatory response syndrome' (SIRS).This activation of the…
- Trial name
- NCT02563652
- Where
- 2 sites in Italy, Norway
- Volunteers
- 101 people
- Sponsor
- St. Olavs Hospital
Aminophylline, Dexmedetomidine
Aminophylline on Recovery in Functional Endoscopic Sinus Surgery Under Dexmedetomidine Hypotensive Anesthesia
This study will be conducted to evaluate the effect of intravenous aminophylline on hemodynamics and recovery of patients receiving dexmedetomidine infusion during functional endoscopic sinus surgery.
- Conditions
- Aminophylline, Dexmedetomidine, Functional Endoscopic Sinus Surgery
- Trial name
- NCT05738135
- Testing
- Aminophylline group, normal saline
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tanta University
Obesity, Premature Recovery From Anesthesia
Armodafinil (Nuvigil), Postoperative Recovery of OSA (Obstructive Sleep Apnea) and Obese Patients
Obstructive sleep apnea (OSA) and obesity is associated with increased perioperative morbidity and mortality. This group of patients is at risk of perioperative desaturations which can be worsened by perioperative sedatives and…
- Trial name
- NCT02478580
- Testing
- Nuvigil
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Texas Southwestern Medical Center
Pain, Postoperative
Biobehavioral Recovery From Surgery and Anesthesia
Reducing postoperative pain leads to increased patient comfort and facilitates speedy recovery and discharge from the hospital following surgery.
- Trial name
- NCT00176696
- Testing
- Use of FACE monitor and BIS monitor
- Volunteers
- 20 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Postoperative Residual Curarization
Comparison of Train of Four, Tetanus 50 and 100 Hz Recovery After Rocuronium Block Reversed by Sugammadex
Despite neuromuscular transmission monitoring and pharmacological reversal allowing a train of four ratio recovery higher than 0.9, patients receiving neuromuscular blocking agent during general anesthesia have a high risk of…
- Trial name
- NCT05003024
- Testing
- TOF SCAN, ITF
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Poitiers University Hospital
Inguinal Hernia Unilateral, Erector Spinae Plane Block
Effect of Preoperative Erector Spinae Plane Block on Recovery Quality, Time to Return to Daily Activities, and Postoperative Pain Scores in Inguinal Hernia Surgery
This study aims to evaluate the effect of the erector spinae plane block (ESPB), performed after surgery, on quality of recovery, postoperative pain, and time to return to daily activities in patients undergoing open inguinal…
- Conditions
- Inguinal Hernia Unilateral, Erector Spinae Plane Block, Quality of Recovery (QoR-15), Numeric Rating Scale
- Trial name
- ESPB for IHR (NCT07509957)
- Testing
- Erector Spinae Plane Block (ESPB) group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanliurfa Education and Research Hospital
Anesthesia Recovery, Anesthesia Emergence
Intravenous Dexmedetomidine For The Quaity Of Emergence From General Anesthesia
In a prospective randomized clinical trial involving adult patients undergoing elective surgery under general anesthesia, the investigators will enroll 216 patients, and evaluate 3 doses of prophylactic dexmedetomidine as a means…
- Conditions
- Anesthesia Recovery, Anesthesia Emergence, Shivering, Postoperative Recovery
- Trial name
- NCT02141412
- Testing
- dexmedetomidine 0.25 µg/kg IV, dexmedetomidine 0.5 µg/kg IV, dexmedetomidine 1 µg/kg IV
- Where
- Lebanon
- Volunteers
- 216 people
- Sponsor
- American University of Beirut Medical Center
Post-anesthesia Recovery
Ketamine Effect on Isoflurane Anesthesia
Ketamine effect on isoflurane anesthesia This study is designed to study the effect of ketamine on isoflurane anesthesia. As both drugs are hypnotic and are used to cause sleep during surgery and other painful procedures, it was…
- Trial name
- NCT03290495
- Testing
- ketamine, saline
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Suprainguinal Fascia Iliaca Block, Varicose Veins
Regional Anesthesia and Recovery After Varicose Vein RFA
This prospective observational study aims to compare the effects of spinal anesthesia and supra-inguinal fascia iliac block (SIFIB) on the quality of postoperative recovery in endovenous radiofrequency ablation (RFA) of varicose…
- Conditions
- Suprainguinal Fascia Iliaca Block, Varicose Veins, Radiofrequency Ablation, Regional Anaesthesia
- Trial name
- NCT07514000
- Testing
- Spinal anesthesia (heavy bupivacaine), SUPRAINGUINAL FACIA ILIACA BLOCK
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Zonguldak Bulent Ecevit University
Intensive Care, Surgical, Postoperative Care
Emergence Agitation in Adult Patients After Intracranial Surgery
Emergence agitation is a frequent complication that can have serious consequences during recovery from general anesthesia. However, agitation has been poorly investigated in patients after craniotomy.
- Conditions
- Intensive Care, Surgical, Postoperative Care, Neurosurgery
- Trial name
- NCT02318199
- Testing
- Anesthesia recovery after intracranial surgery
- Where
- 4 sites in China
- Volunteers
- 400 people
- Sponsor
- Capital Medical University
Abdominal Muscles/Ultrasonography, Adult
TAP Catheters Versus Intrathecal Morphine for Cesarean Section
Morphine, when given as part of spinal anesthesia, is associated high incidence of nausea and pruritus, which may affect quality of recovery.
- Conditions
- Abdominal Muscles/Ultrasonography, Adult, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage
- Trial name
- NCT01593280
- Testing
- TAP catheter, intrathecal morphine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stamford Anesthesiology Services, PC