Clinical trials: Anesthesia, Recovery
Inflammatory Response
Effect of Intravenous Ibuprofen on Inflammatory Responses in Patients Undergoing Surgery With General Anesthesia.
The administration of anti-inflammatory drugs such as ibuprofen before and after surgery has not been studied extensively. Subjects are being asked to participate in this study because they are scheduled for surgery and because…
- Trial name
- NCT01377441
- Testing
- Ibuprofen
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
Hypoxemia
Effect of Different Oxygen Concentrations Before Extubation After General Anesthesia on Hypoxemia After Extubation in Post-anesthesia Care Unit
Before extubation during the anesthesia recovery period, 100% oxygen is routinely inhaled to increase the oxygen reserves, maximizing the time window for anesthesiologists to adjust strategies when they encounter hypoxemia after…
- Trial name
- NCT07293286
- Testing
- 100% oxygen concentration inhaled, 30% oxygen concentration inhaled
- Where
- China
- Volunteers
- 590 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Benign Prostatic Hyperplasia, Transurethral Resection of the Prostate
Tranexamic Acid for Bleeding Reduction During TURP Surgery
Transurethral resection of the prostate (TURP) is commonly performed in elderly patients and may be associated with perioperative bleeding leading to postoperative anemia and delayed recovery.
- Conditions
- Benign Prostatic Hyperplasia, Transurethral Resection of the Prostate, Perioperative Bleeding, Anemia, Postoperative
- Trial name
- TXA-TURP (NCT07460518)
- Testing
- Tranexamic Acid
- Where
- Morocco
- Volunteers
- 80 people
- Sponsor
- Hamza Najout
Geriatric Patient Care Improvement, Postoperative Delirium (POD)
The Effects of Anesthesia Depth Monitoring on Postoperative Recovery and Cognitive Functions in the Geriatric Patient Population
This study will be conducted on patients aged 65 and older scheduled for surgery due to lumbar or cervical disc herniation. General anesthesia is routinely used for these types of surgeries in the hospital.
- Conditions
- Geriatric Patient Care Improvement, Postoperative Delirium (POD), Burst Suppression
- Trial name
- NCT06844279
- Testing
- Control Group: Standard Hemodynamic Monitoring, Processed Electroencephalogram (BIS Index), Processed Electroencephalogram (DSA Mode)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Aslıhan Güleç
Anesthesia, Spinal
Comparison of Clorotekal and Bupivacaine for Short Obstetric Surgery
The following obstetric procedures are commonly performed with spinal anesthesia on labor and delivery: bilateral tubal ligation, external cephalic version, cerclage insertion, cerclage removal, minimally invasive fetal surgery…
- Trial name
- CLIMB (NCT03967288)
- Testing
- Chloroprocaine Injection [Clorotekal], Bupivacaine Hydrochloride 0.75% Injection Solution
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Morbid Obesity
Remifentanil Dosing Regimes for Anesthesia in Bariatric Surgery: Characteristics of Early Recovery
Early recovery characteristics are important for patients' safety and operating room turnover. Our aim was to compare fundamental methods for dosing remifentanil during morbid obesity surgeries: a manual infusion and a…
- Trial name
- NCT04690088
- Where
- Lithuania
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Hip Hemiarthroplasty
Quality Of Recovery After Pericapsular Nerve Group (PENG) Block For Hip Hemiarthroplasty Under Spinal Anesthesia
Patients undergoing hip hemiarthroplasty can benefit significantly from regional anesthesia in terms of pain management and recovery . There is a wide range of regional anesthetic techniques.
- Trial name
- NCT06369948
- Testing
- Pericapsular Nerve Group (PENG) Block, elective hip hemiarthroplasty without receiving a PENG block., bupivacaine 0.5% injection
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Fayoum University Hospital
Obstetric Pain, Postpartum Depression
Ketamine to Improve Recovery After Cesarean Delivery - Part 1
The objective of this study is evaluate the breastmilk transfer and pharmacokinetics (Part 1) and effectiveness (Part 2) of a post-cesarean delivery intravenous ketamine bolus-and-infusion strategy, as a preventive analgesic…
- Conditions
- Obstetric Pain, Postpartum Depression, Breastfeeding, Pain, Acute
- Trial name
- KINETIC (NCT04037085)
- Testing
- Ketamine
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Neuromuscular Blockade, Cholecystectomy
Acceleromyography Versus Electromyography for Neuromuscular Recovery Assessment at the End of Surgery
This prospective observational study aims to evaluate the agreement between acceleromyography and electromyography for measuring train-of-four (TOF) ratio at the end of surgery before reversal of neuromuscular blockade.
- Trial name
- NCT07739862
- Testing
- Simultaneous Acceleromyography and Electromyography Monitoring
- Where
- Chile
- Volunteers
- 70 people
- Sponsor
- Clínica Dávila
Anesthesia, Anesthesia Recovery Period
Effect of Epidural Anesthesia and Analgesia on Quality of Recovery After Radical Prostatectomy.
Postoperative quality of recovery (QoR) could be related to anesthesia and postoperative analgesia. This study is exploring early QoR after radical prostatectomy in the two groups of anesthesia.
- Conditions
- Anesthesia, Anesthesia Recovery Period, Radical Prostatectomy, Patient Satisfaction
- Trial name
- QoR (NCT04587505)
- Testing
- Epidural anesthesia with light general anesthesia, Postoperative epidural analgesia, General anesthesia
- Where
- Croatia
- Volunteers
- 61 people
- Sponsor
- University Hospital of Split
Esophageal Cancer, Complication, Postoperative
The Effects on Major Organ Complications on Esophagectomy of New Anesthetic ERAS Strategy: a Prospective Investigation
The goals of this study are to testify the effectiveness on enhancement recovery by new anesthetic ERAS (Enhanced recovery after surgery) strategy.
- Conditions
- Esophageal Cancer, Complication, Postoperative, Anesthesia
- Trial name
- ERAS (NCT03176680)
- Testing
- Fluid therapy optimization
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Hernia, Umbilical, Clonidine
Clonidine in Ultrasound-guided Rectus Sheath Block for Outpatient Umbilical Hernioplasty
This clinical trial aims to evaluate the effectiveness of an ultrasound-guided nerve block technique as the sole anesthetic method for patients undergoing outpatient umbilical hernia surgery.
- Conditions
- Hernia, Umbilical, Clonidine, Pain, Postoperative, Ambulatory Surgical Procedures
- Trial name
- NCT07062497
- Testing
- Rectus Sheath Block, Rectus Sheath Block with Clonidine
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Acute Abdomen, Abdominal Trauma
Enhanced Recovery After Surgery (ERAS) in Patients Undergoing Emergency Laparotomy
The goal of this clinical trial is to test the safety and effectiveness of the ERAS protocols compared to a conventional care protocols in patients who received emergency laparotomy.
- Conditions
- Acute Abdomen, Abdominal Trauma, Emergency Surgery
- Trial name
- ERAS (NCT06182488)
- Testing
- ERAS protocols, Conventional protocols
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Tianjin Medical University
Pain, Acute
Effects of Transcutaneous Electrical Nerve Stimulation (TENS) Following Hysterectomy
The purpose of this study is to evaluate the effect of Transcutaneous Electrical Nerve Stimulation (TENS) in patients after abdominal hysterectomy surgery.
- Trial name
- NCT03072888
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Tokat Gaziosmanpasa University
Brain Tumor
Quality of Recovery Awake Versus Asleep Craniotomy
Awake craniotomy (AC) is an anesthetic and surgical technique commonly used to resect tumors involving or adjacent to the eloquent or motor cortices, those portions of the brain that are responsible for language and motor skills…
- Trial name
- NCT02228993
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Northwestern University
Chronic Sinusitis, Postoperative Pain
Opioid-Free Anesthesia in FESS: A Prospective ERAS Study
1. Information for Patients and Families What is this study about? When patients undergo functional endoscopic sinus surgery (FESS), strong pain relievers called opioids are traditionally used during anesthesia.
- Conditions
- Chronic Sinusitis, Postoperative Pain, Postoperative Nausea and Vomiting (PONV), Surgical Field Visibility
- Trial name
- OFA-FESS (NCT07812389)
- Testing
- Dexmedetomidine, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Filiz Kaya
Ventilatory Depression, Postoperative Respiratory Failure
The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia
In this randomized-controlled trial the investigators will examine the effect of oxygen supplementation on the recovery of breathing for 90 minutes in the immediate post-anesthesia period starting from extubation of the trachea.
- Trial name
- NCT05379673
- Testing
- Oxygen Gas for Inhalation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Opioid-Free Anaesthesia
Accelerated Recovery Following Opioid-free Anaesthesia in Supratentorial Craniotomy
Anaesthesia for craniotomy (open skull/brain) surgery focuses on maintaining blood supply to brain, avoiding factors that may lead to increased pressure in brain and aim for early neurological recovery.
- Trial name
- NCT05681429
- Testing
- Lignocaine, Dexmedetomidine, Sevoflurane, Paracetamol, Parecoxib
- Where
- Malaysia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Anesthesia
Ultrasound-guided Serratus Plane Block for the Quality of Recovery After Modified Radical Mastectomy
Regional anesthesia improves quality of recovery after surgery in many studies. Ultrasound-guided serratus plane block is a novel technique which may be a viable alternative to current regional anesthetic techniques.
- Trial name
- NCT02691195
- Testing
- Ropivacaine, 0.9% Nacl
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Fujian Provincial Hospital
Elective Surgical Procedures, Laparoscopy
Nitrous Oxide Added at the End of Sevoflurane Anesthesia and Recovery
Addition of nitrous oxide N2O towards the end of prolonged isoflurane anesthesia hastens patients recovery. The hypothesis is that the addition of N2O at the end of prolonged sevoflurane anaesthesia also hastens early recovery…
- Conditions
- Elective Surgical Procedures, Laparoscopy, Laparotomy, Anesthesia, General
- Trial name
- SEVONATE (NCT03420586)
- Testing
- Nitrous Oxide
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- General Hospital Zadar