Clinical trials: Anesthesia, Recovery
Postoperative Pain
Effects of Regional Anesthesia Following Mastectomy
Patients of breast surgery dated between April 2016 and March 2021 will be scanned in three groups; solely induced general anesthesia, general anesthesia induced with Erector Spinae Plane Block, and general anesthesia induced…
- Trial name
- NCT05276440
- Volunteers
- 182 people
- Sponsor
- Koc University Hospital
Anesthesia Recovery Period, Pain, Postoperative
Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic Surgery
The main hypothesis of this study is that preoperative administration of controlled-release (CR) oxycodone may reduce acute postoperative pain and improve time to discharge from the post-anesthesia care unit in patients…
- Trial name
- NCT00681174
- Testing
- Morphine, oxycodone, Paravertebral block
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- University of Parma
Pain, Postoperative, Rebound Pain
Intravenous Dexamethasone With Single-Shot Versus Continuous Brachial Plexus Block for Rebound Pain After Shoulder Surgery
Shoulder surgery often causes severe pain after the operation. To control this pain, doctors commonly perform a nerve block (interscalene brachial plexus block), which numbs the shoulder area.
- Conditions
- Pain, Postoperative, Rebound Pain, Shoulder Injuries, Rotator Cuff Injuries
- Trial name
- NCT07699744
- Testing
- Dexamethasone (IV), Single-shot interscalene brachial plexus block, Continuous interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Anesthesia; Bariatric Surgery
Automated Closed Loop Propofol Anaesthesia Versus Desflurane Inhalation Anaesthesia In Bariatric Surgery
Complete recovery from anaesthesia is absolutely desirable in the obese patients to avoid postoperative airway, oxygen ventilation or sleep apnea related complications.
- Trial name
- NCT03099616
- Testing
- Propofol, Desflurane
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Dr Nitin Sethi
Pain, Acute, Surgery
ESP Block in VATS: Programmed Intermittent Bolus Versus Continuous Infusion on Quality of Recovery
Fascial plane blocks, such as ESP, rely on the spread of local anaesthetic on an interfacial plane, automated boluses may be particularly useful for this group of blocks.
- Trial name
- NCT05181371
- Testing
- Ultrasound Guided ESP Block with Programmed Intermittent Bolus (PIB) for VATS, Ultrasound Guided ESP Block with Continuous Infusion (CI) for VATS
- Where
- 2 sites in Ireland
- Volunteers
- 60 people
- Sponsor
- Mater Misericordiae University Hospital
Enhanced Recovery After Anesthesia
Intraoperative Lidocaine Infusion
This study aims to evaluate the analgesic and anti-inflammatory effect of perioperative intravenous lidocaine infusion and in turn the return of gastric motility in patients undergoing elective laparoscopic cholecystectomy.
- Trial name
- IV (NCT07150481)
- Testing
- IV Lidocaine infusion, IV normal saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Colorectal Disorders, Postoperative Ileus
Does Epidural Anesthesia Reduce Postoperative Ileus Following Colorectal Surgery?
The use of epidural analgesia (EA) has been suggested as an integral part of an enhanced recovery program for colorectal surgery. However, the effects of EA on postoperative ileus remain controversial.
- Trial name
- NCT04429425
- Testing
- epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Quality of Recovery
Quality of Recovery of Remimazolam Versus Sevoflurane in Transurethral Bladder Resection.
This study was designated to investigate the quality of recovery after transurethral bladder resection. Because, patients undergoing transurethral bladder resection are mostly old age, and because of catheter-related bladder…
- Trial name
- NCT05356091
- Testing
- Sevoflurane, Remimazolam
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Kangbuk Samsung Hospital
Cognition Disorders in Old Age
Early Cognitive Function in Elderly Patients After Laser Laryngeal Surgery: Des vs Prop
Postoperative cognitive impairment is one of the most common complications in elderly surgical patients. Laser laryngeal surgery is a short procedure, but characterized by high risk of disastrous airway fire.
- Trial name
- POCDLLS (NCT03194074)
- Testing
- Propofol, Desflurane
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Osteoarthritis, Hip
Measured Hypocretin Levels and Recovery After Hip Surgery
A specific group of neurons in the brain produces hypocretin, a peptide which has been established as an important regulator of sleep and wakefulness.
- Trial name
- NCT01009710
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Anesthesia, Anesthesia; Adverse Effect
Comparison of an Opioid-Free Anesthesia Protocol Versus Standard Practices on Early and Late Post-operative Recovery
Opioid-Free Anesthesia (OFA) is an anesthesia protocol that does not use morphine, and is increasingly used routinely. Indeed, this protocol would theoretically allow a better post-operative analgesic control, a lower incidence…
- Conditions
- Anesthesia, Anesthesia; Adverse Effect, Opioid Analgesic Adverse Reaction, Post-Op Complication
- Trial name
- SOFA (NCT04797312)
- Testing
- Opioid Free Anaesthesia protocol, standard practice protocol based on the use of opioids (sufentanil or remifentanil)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Angers
Anesthesia, General, Recovery Period, Anesthesia
Recovery From General Anesthesia
General anesthesia allows people to have surgery without experiencing the procedure or pain. To remain unconscious, the depth of sleep must be monitored.
- Trial name
- NCT00165971
- Testing
- BIS monitoring
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Remote Monitoring of Pain and Recovery Quality in the Immediate Postoperative Period Using a Digital Health Tool, Pain, Postoperative
Remote Assessment of Pain and Recovery Quality After Surgery Using a Digital Form: A Pilot Study
After surgery, doctors need to know how patients are doing, especially in the first hours after they leave the recovery room. This can be hard to track once patients go to a regular hospital room, and some symptoms - like pain or…
- Conditions
- Remote Monitoring of Pain and Recovery Quality in the Immediate Postoperative Period Using a Digital Health Tool, Pain, Postoperative, Postoperative Nausea and Vomiting, Recovery of Function (G11.427.698.620)
- Trial name
- NCT07794267
- Testing
- Digital web-based postoperative follow-up form
- Where
- Brazil
- Volunteers
- 213 people
- Sponsor
- Hospital de Base
Cesarean Sections
Thoracic vs Lumbar Spinal Anesthesia for Cesarean Delivery
This randomized controlled trial aims to compare the effects of thoracic segmental spinal anesthesia and conventional lumbar spinal anesthesia on postoperative recovery in patients undergoing elective cesarean section.
- Trial name
- NCT07567612
- Testing
- Thoracic Segmental Spinal Anesthesia, Lumbar Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Adiyaman University Research Hospital
Postoperative Respiratory Condition
Effect of Neuromuscular Reversal With Sugammadex on Postoperative Recovery Profile
Suboptimal reversal of neuromuscular blockage after surgery is possibly related to unfavorable postoperative respiratory conditions and elevated pain levels.
- Trial name
- Neuropa (NCT02243943)
- Testing
- Sugammadex, Neostigmine
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Leiden University Medical Center
Hemodynamic Instability, Postoperative Recovery
Subanesthetic Esketamine for Hemodynamic Stability and Recovery in Elderly Thoracic Surgery Patients
This retrospective study evaluated the effects of a subanesthetic dose of esketamine (0.25 mg/kg) on intraoperative hemodynamic stability and postoperative recovery quality in elderly patients (aged 65-75) undergoing thoracic…
- Conditions
- Hemodynamic Instability, Postoperative Recovery, Thoracic Surgery, Anesthesia, General
- Trial name
- NCT07064408
- Testing
- Esketamine, Normal Saline (0.9% Sodium Chloride), Midazolam
- Where
- China
- Volunteers
- 230 people
- Sponsor
- Hebei Medical University Fourth Hospital
Cardiac Surgery, Peri Operative Medicine
Risk Factors of Atrial Fibrillation After Cardiac Surgery
Supraventricular arrhythmias complicate more than 40% of cardiac surgeries and are associated with an increased risk of bleeding, stroke, heart failure, and death.
- Conditions
- Cardiac Surgery, Peri Operative Medicine, Thoracic Surgery, Cardiopulmonary Bypass
- Trial name
- PFAS (NCT07625033)
- Where
- France
- Volunteers
- 918 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Colonoscopy, Anesthesia
Comparison of Post Anesthetic Recovery Time in Sedated Patients for Colonoscopy
Colonoscopy is an important diagnostic and therapeutic tool in colon disorders. Different drugs and levels of sedation can be used in its accomplishment. There is no consensus on which is the ideal.
- Trial name
- CPART (NCT03813303)
- Testing
- Midazolam, Fentanyl, Propofol
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Anesthesiology Management
Recovery From Anesthesia After Robotic Assisted Radical Cystectomy
Robot-assisted radical cystectomy (RARC) requires specific surgical conditions: steep Trendelenburg position, prolonged pneumoperitoneum, effective neuromuscular block until the final stages of surgery.
- Trial name
- NCT03144453
- Testing
- Sugammadex Injectable Product, Neostigmine, Atropine
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- Regina Elena Cancer Institute
Hemorrhoids, Postoperative Pain
Pudendal Nerve Block Techniques for Pain Control After Hemorrhoidectomy
Hemorrhoidectomy is frequently associated with severe postoperative pain despite multimodal analgesia. Ultrasound-guided pudendal nerve block has become an effective regional analgesic technique, but it remains unknown whether…
- Trial name
- PINPOINT (NCT07813338)
- Testing
- Transgluteal Pudendal Nerve Block, Transperineal pudendal nerve block
- Volunteers
- 140 people
- Sponsor
- Vinmec Healthcare System