Clinical trials: Anesthesia, Recovery
Agitation, Emergence, Postoperative Delirium
WashIn /WashOut Procedure To Prevent Agitation During Recovery After Inhalational Anesthesia With Sevoflurane
Inhalation anesthesia is the most frequently used technique and is performed in around 70% of surgeries worldwide. Sevoflurane is the most frequently used halogenated anesthetic and is used in 2/3 of the cases.
- Conditions
- Agitation, Emergence, Postoperative Delirium, Postoperative Cognitive Dysfunction
- Trial name
- OPERA (NCT04765488)
- Testing
- WashIn /WashOut
- Where
- 3 sites in Russia
- Volunteers
- 200 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
In Vitro Fertilization, Postoperative Recovery
Estrogen Levels and Postoperative Recovery in IVF Patients
This prospective observational study aims to evaluate the relationship between supraphysiologic serum estrogen levels and postoperative recovery quality in patients undergoing IVF procedures under general anesthesia.
- Conditions
- In Vitro Fertilization, Postoperative Recovery, Estrogens, Anesthesia Recovery Period
- Trial name
- NCT06925633
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Konya City Hospital
Anesthesia,General
Utility of the Smart Pilot View in Clinical Practice: A Two Center Prospective Observational Study
Recently, a new software program for anesthesia has been developed, called Smart Pilot View. This program monitors the patient, the anesthetic drugs given, and the calculated depth of the anesthesia.
- Trial name
- NCT01467167
- Where
- 2 sites in Netherlands, Switzerland
- Volunteers
- 400 people
- Sponsor
- University Medical Center Groningen
Down Syndrome
The Effects of Inhalational Anaesthetics in Cognitive Functions in Down Syndrome Patients
Recovery of the cognitive functions and recovery features after general anaesthesia in Down syndrome patients. A comparison of Sevoflurane and Desflurane.
- Trial name
- NCT02971254
- Testing
- Sevoflurane, Desflurane
- Where
- Greece
- Volunteers
- 39 people
- Sponsor
- Asklepieion Voulas General Hospital
Acute Pain, Post Operative Analgesia
Analgesic Efficacy of Combined PECS II and PIP Block Versus Thoracic Paravertebral Block Post-Mastectomy
Postoperative pain management is crucial for patients undergoing mastectomy for breast cancer. Regional analgesia techniques, such as the Thoracic Paravertebral Block (TPVB), are commonly used to reduce pain and opioid…
- Conditions
- Acute Pain, Post Operative Analgesia, Post Operative Pain, Acute, Breast Cancer
- Trial name
- PECS-TPVB (NCT07738770)
- Testing
- Combined PECS II and Superficial PIP Block, Thoracic paravertebral block (TPVB)
- Where
- Indonesia
- Volunteers
- 72 people
- Sponsor
- Dharmais National Cancer Center Hospital
Cardiac Surgery Patients
High-dose Opioid Versus Opioid-sparing Anaesthesia in Cardiac Surgery
BACKGROUND In cardiac surgery, high-dose opioid contributes to adverse events associated with poor postoperative outcomes. There is growing evidence that nerve block-based multi-modal anesthesia protocols may reduce…
- Trial name
- NCT06437886
- Testing
- opioid-sparing protocol
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Cholecystectomy, Laparoscopic, Noise
The Effect of Noise Control During Anesthesia Induction in Laparoscopic Cholecystectomy Surgery
This study aims to determine the effects of active and passive noise control method and headphone usage and noise level during anesthesia induction in laparoscopic cholecystectomy surgery on hemodynamic parameters, pain, nausea…
- Conditions
- Cholecystectomy, Laparoscopic, Noise, Anesthesia Induction
- Trial name
- Anesth-noise (NCT06666686)
- Testing
- Active noise control headphone, Passive noise control headphone
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Agitated; State, Acute Reaction to Stress
Does Low Flow Anesthesia Reduce Postanaesthetic Emergence Agitation?
In this study, the investigators aimed to compare postanesthetic agitation in patients undergoing laparotomic gynecological surgery under general anesthesia using sevoflurane at a fresh gas flow rate of 2 L / min with fresh gas…
- Trial name
- NCT03862391
- Testing
- Analgesics, Antiemetics
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Ceserean Section, Obstetric Quality of Recovery
Anesthetic Technique and Quality of Recovery After Cesarean Delivery
The goal of this prospective observational study is to evaluate whether the type of neuraxial anesthesia is associated with postoperative quality of recovery in adult women undergoing cesarean delivery.
- Conditions
- Ceserean Section, Obstetric Quality of Recovery, Neuraxial Anesthesia
- Trial name
- NCT07896733
- Testing
- Spinal anesthesia (heavy bupivacaine), epidural anesthesia, combine spinal epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Marmara University
General Anesthesia, İnhalation Anesthetics
Effects of Anesthesia Type on QoR-40
To compare the effects of total intravenous anesthesia and inhalation anesthesia used for maintenance on postoperative recovery in patients undergoing septorhinoplasty surgery under general anesthesia, using the recovery quality…
- Conditions
- General Anesthesia, İnhalation Anesthetics, Quality of Recovery
- Trial name
- NCT06423313
- Testing
- maintenance of anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Pain Management, Colorectal Surgery
Opioid-Free Anesthesia in Colorectal Surgery, 2025 (OFA-CRC-2025)
This study wants to find out if using a pain control method without opioids (Opioid-Free Anesthesia or OFA) works as well as or better than standard anesthesia (which uses opioids) for adults having minimally invasive…
- Conditions
- Pain Management, Colorectal Surgery, Opioid Free Anesthesia, Postoperative Complications
- Trial name
- OFA-CRC-2025 (NCT07771049)
- Testing
- Opioid-Free Anesthesia (OFA), Opioid-Based Anesthesia (OBA)
- Where
- 2 sites in Spain
- Volunteers
- 200 people
- Sponsor
- Hospital Universitario La Fe
Anesthesia, Anesthesia Recovery Period
Effect of Epidural Anesthesia and Analgesia on Quality of Recovery After Unilateral Nephrectomy.
Different modality of anesthesia and analgesia could influence a postoperative quality of recovery (QoR). This study is exploring early QoR after unilateral nephrectomy in the two groups of anesthesia.
- Conditions
- Anesthesia, Anesthesia Recovery Period, Nephrectomy, Patient Satisfaction
- Trial name
- QoR (NCT04521556)
- Testing
- Epidural anesthesia with light general anesthesia, Postoperative epidural analgesia, General anesthesia
- Where
- Croatia
- Volunteers
- 80 people
- Sponsor
- University Hospital of Split
Anesthesia, Analgesia
The Impact of the Anaesthetic Technique Employed on the Quality of Recovery in Patients Undergoing Hysterectomy Surgery.
The objective of this study is to evaluate the results of different anesthesia methods (general anesthesia with epidural catheter application and spinal anesthesia with epidural catheter application) applied in elective…
- Conditions
- Anesthesia, Analgesia, Acute Pain
- Trial name
- NCT06461832
- Testing
- Group 1, Group 2
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Samsun University
Gynecologic Surgery, General Anesthesia
Long-term Follow-up of Bio-signals and Quality of Recovery Following Implementation of ERAS Based on the Mobile Application
The goal of this clinical trial is to evaluate the effect of an Enhanced Recovery After Surgery (ERAS) protocol in patients undergoing gynecologic laparoscopic or robotic surgery under general anesthesia.
- Trial name
- NCT07868952
- Testing
- Enhanced Recovery After Surgery, Usual Care
- Where
- South Korea
- Volunteers
- 350 people
- Sponsor
- Wonju Severance Christian Hospital
Emergence Agitation, Rhinoplasty
Use of Subanesthetic Dose Propofol Before Extubation
This study investigates whether administering a low, sub-anesthetic dose of propofol before extubation can reduce emergence agitation and improve perioperative comfort in patients undergoing rhinoplasty.
- Conditions
- Emergence Agitation, Rhinoplasty, Patient Satisfaction
- Trial name
- NCT07276633
- Testing
- Propofol (Sub-Anesthetic Dose)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Yuzuncu Yil University
Brain Activity Under Sedation
EEG Studies of Induction and Recovery From Propofol Induced General Anesthesia
The purpose of this study is to investigate how the commonly used anesthetic drug propofol works in the brain to produce loss of consciousness.
- Trial name
- NCT01543633
- Testing
- Propofol
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Kidney Transplantation, Anxiety
The Effects of Pre-operative Anxiety on Anesthetic Recovery and Post-operative Pain in Donor Nephrectomy
Kidney transplant is the most effective choice of treatment for patients with end-stage kidney failure in terms of quality of life and longevity. Today, 20-25% of kidney transplantations are implemented with living donors.
- Conditions
- Kidney Transplantation, Anxiety, Pain, Acute, Anesthesia Recovery Period
- Trial name
- NCT03131258
- Testing
- Donor Nephrectomy
- Volunteers
- 48 people
- Sponsor
- Ege University
Video-assisted Thoracic Surgery
Effect of the PIEB Versus CEI on the Quality of Postoperative Recovery in Patients Undergoing VATS Lobectomy
In recent years, lobectomy under VATS(Video-assisted thoracic surgery,VATS) has gradually emerged, but there is still a proportion of patients with postoperative pain that affects their postoperative recovery.
- Trial name
- NCT05930405
- Testing
- programmed intermittent epidural bolus, continuous epidural infusion
- Where
- China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Surgery
Brain Function Monitoring During Surgery
The purpose of this research is to gather information on the effectiveness of the Sedline Brain Function Monitor, and its use in this study to determine whether monitoring the brain activity during anesthesia will improve…
- Trial name
- NCT06619730
- Testing
- Sedline Brain Function Monitor
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago
Emergence Delirium in Pediatric Anesthesia, Perioperative Ketonemia and Its Association With Recovery Outcomes in Children
"KETOMED: Ketonemia and Risk of Emergence Delirium in Children Undergoing General Anesthesia - A Multicenter Observational Study"
The objective of this observational study is to evaluate the relationship between ketonemia and emergence delirium in children undergoing general anesthesia.
- Trial name
- KETOMED (NCT07249736)
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital Clínico Universitario de Valladolid