Clinical trials: Anesthesia, Recovery
Regional Anesthesia Morbidity
Efficacy of SAP Block Versus ESP Block in VATS Surgery
During VATS (Video assisted thoracic surgery) small incisions are made in the patient's chest through which a camera and instruments are inserted to allow a lung operation to be performed.
- Trial name
- ESPvSAP (NCT03862612)
- Testing
- regional anaesthesia with Levobupivicaine 0.25% 30mls with two methods either erector spinae plane block or serratus anterior plane block
- Where
- Ireland
- Volunteers
- 60 people
- Sponsor
- Mater Misericordiae University Hospital
Anesthesia Recovery Period, Neuromuscular Blockade
The Dose of Sugammadex for Rapid Reversal of Profound Neuromuscular Block in Young and Elderly Patients
To find out the dose of sugammadex for recovery of the TOF ratio to 0.9 within 2 minutes from profound rocuronium-induced neuromuscular block in young and elderly adult patients.
- Trial name
- NCT01890057
- Testing
- Sugammadex
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Severance Hospital
Total Knee Arthroplasty, Post Operative Analgesia
Comparing Postoperative Functional Recovery and Analgesic Efficacy of a Single Shot Sciatic Nerve Block Versus Posterior Capsule/Fat Pad Infiltration of Local Anesthetic for Total Knee Arthroplasty
Many methods of pain relief have been implemented in an attempt to provide safe and effective analgesia for patients following total knee arthroplasty.
- Trial name
- NCT00677261
- Testing
- Sciatic Nerve Block, Posterior capsule infiltration with local anesthetic
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- Sunnybrook Health Sciences Centre
Anesthesia, Sedation
EEG-Guided Sedation in ERCP Procedures
Patients undergoing ERCP have a wide range from patients with poor general condition and septicaemia findings to outpatients who come as day patients without any other additional disease.
- Conditions
- Anesthesia, Sedation, Sedation Complication, Anesthesia, Intravenous
- Trial name
- ERCP-EEG (NCT06866886)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ankara City Hospital Bilkent
Unruptured Cerebral Aneurysm
Identification of Genetic Polymorphisms Related to Propofol Requirement and Recovery Through Genome-wide Association Study (GWAS) in Total Intravenous Anesthesia for Clipping of Unruptured Cerebral Aneurysm in Korean Population
In neurosurgical anesthesia, propofol based total intravenous anesthesia (TIVA) is frequently used due to brain relaxation and less effect on electrophysiologic monitoring.
- Trial name
- NCT03087383
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Yonsei University
Anesthesia
Optimizing Post-operative Recovery in Bariatric Patients With Obstructive Sleep Apnea Undergoing Outpatient Surgery: A Comparison of Sugammadex and Neostigmine
This study assesses the efficacy of sugammadex against neostigmine for hastening recovery from neuromuscular blockade and optimizing pulmonary function in obese patients with obstructive sleep apnea presenting for outpatient…
- Trial name
- NCT04570150
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of California, San Diego
Breast Cancer, Nerve Block
Erector Spinae Block vs. Placebo Block Study
Regional anaesthesia combined with general anaesthesia has become common in the perioperative management of breast cancer surgery patients. Regional techniques have been recognised to provide excellent post-operative analgesia.
- Conditions
- Breast Cancer, Nerve Block, Regional Anesthesia, Neuromuscular Blockade
- Trial name
- NCT03978780
- Testing
- Erector spinae plane block
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Women's College Hospital
Fraily, Abdominal Surgery
Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery.
This is a bicentric, prospective, non-pharmacological, randomized study designed to compare the efficacy and safety of awake neuraxial anesthesia with sedation versus general anesthesia in frail patients undergoing elective major…
- Conditions
- Fraily, Abdominal Surgery, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- SAFE-AWARENESS (NCT07486336)
- Testing
- Neuraxial anesthesia, General Anesthesia, avoidance of GABAergic-drugs strategy
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Opioid Use, Anesthesia Morbidity
Paragastric Autonomic Neural Blockade as Part of Combined Anesthesia.
To evaluate the effect of early autonomic blockade on the consumption of remifentanil and halogenated anesthesia in the intraoperative period during laparoscopic sleeve gastrectomy.
- Trial name
- NCT05668845
- Testing
- PG-ANB performed at the outset of LSG, PG-ANB performed at the end of the LSG
- Where
- Colombia
- Volunteers
- 79 people
- Sponsor
- Universidad Simón Bolívar
Anesthesia, Recovery
Reduction in Sedation: Colonoscopy vs Esophagoduodenoscopy First
The purpose of this research is to compare the effect of different procedural sequences on the time to recovery and the propofol sedation requirements in patients undergoing bidirectional endoscopy with sedation.
- Trial name
- RECoVER (NCT04096339)
- Testing
- Colonoscopy followed by EGD, EGD followed by Colonoscopy
- Where
- Lebanon
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
ERAS
Effect of Regional Anesthesia on Enhanced Recovery After Spine Surgeries
This study will be carried out on 80 patients who will be presented for different spine surgeries under general anesthesia and regional anesthesia technique in Tanta university hospitals.
- Trial name
- NCT04586257
- Testing
- Erector spinae plane block, Throacolumbar interfacial plane block
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Tanta University
Sleep Deprivation, Critical Incident
Recovery Napping Protocol for Anesthesiologist Performance
Sleep deprivation impacts performance of shift workers in health care. Anesthesiologists are a population at risk that endures stressful situations and changing working hours.
- Conditions
- Sleep Deprivation, Critical Incident, Sleep, Anesthesia
- Trial name
- R-NAP (NCT05619081)
- Testing
- POWERNAP
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Claude Bernard University
Pain
Supraclavicular Versus Interscalene Block for Shoulder Surgery
The purpose of this study is to compare the supraclavicular block to interscalene block in patients undergoing arthroscopic shoulder surgery.
- Trial name
- NCT02486549
- Testing
- Supraclavicular Block, Interscalene Block, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Tokat Gaziosmanpasa University
PACU Stay After THA Under Spinal Anaesthesia, PACU Stay After TKA Under Spinal Anaesthesia
Recovery at the Post Anaesthetic Care Unit After Hip and Knee Arthroplasty
To clarify patient related problems in the Post Anaesthetic Care Unit (PACU) immediately after fast-track hip and knee arthroplasty.
- Trial name
- NCT01178489
- Where
- Denmark
- Volunteers
- 170 people
- Sponsor
- Hvidovre University Hospital
Anesthesia, Intravenous, Pain, Postoperative
Virtual Reality in the Operating Room
This is a randomized, controlled trial designed to investigate whether the use of virtual reality immersive relaxation during hand/arm operations can allow for a relaxing operating room experience for patients while potentially…
- Conditions
- Anesthesia, Intravenous, Pain, Postoperative, Delayed Recovery From Anesthesia, Satisfaction
- Trial name
- OR-VR (NCT03614325)
- Testing
- Virtual Reality Immersive Relaxation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Beth Israel Deaconess Medical Center
Atrial Fibrillation, Electric Countershock
BIS-Guided Sedation Versus Standard Clinical Sedation During Elective Electrical Cardioversion for Atrial Fibrillation
Electrical cardioversion (ECV) is a standard procedure used to restore normal heart rhythm in patients with atrial fibrillation (AF) by delivering a brief electrical shock to the heart.
- Conditions
- Atrial Fibrillation, Electric Countershock, Deep Sedation
- Trial name
- BIS-ECV-RCT (NCT07569016)
- Testing
- BIS-guided propofol sedation, Clinical-guided propofol sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Emergence Time
Effects of Preoperative Sleep Disorders on Perioperative Anesthesia Depth and Recovery Quality in Patients Undergoing Noncardiac Surgery
A Single-Center, Prospective Observational Cohort Study Comparing Perioperative Electroencephalographic Anesthesia Depth Parameters (Electroencephalographic Index, SE/RE Entropy, Burst Suppression Ratio) Between Patients With…
- Trial name
- NCT07675993
- Testing
- Exposed cohort (sleep disorder group), Control cohort (non-sleep disorder group)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Opioid-Free Anesthesia, Laparoscopic Sleeve Gastrectomy
Effect of Opioid-free Analgesia and Anesthesia on the Quality of Postoperative Recovery and Nausea Vomit in Patients Receiving Laparoscopic Sleeve Gastrectomy
The purpose of the intraoperative use of opioids is to reduce the amount of sedative medication and to ensure effective analgesia.
- Conditions
- Opioid-Free Anesthesia, Laparoscopic Sleeve Gastrectomy, Postoperative Vomiting, Postoperative Recovery
- Trial name
- NCT06305221
- Testing
- Opioid-free Analgesics (esketamine, dexmedetomidine), Opioid Anesthetics (sufentanil and remifentanil)
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Beijing Friendship Hospital
Sleep Quality, Postoperative Recovery
Sleep During Recovery: Effect of Preoperative Regional Block on Postoperative Sleep Quality in Mastectomy Patients
This prospective observational study investigates the impact of preoperative regional anesthesia on postoperative sleep quality in patients undergoing mastectomy.
- Conditions
- Sleep Quality, Postoperative Recovery, Anesthesia Techniques
- Trial name
- NCT07051434
- Testing
- Regional Analgesic Block
- Volunteers
- 66 people
- Sponsor
- Istinye University
Heart Valve Diseases, Enhanced Recovery After Surgery
Multicentre Clinical Study of Ultra-Fast-Track Anaesthesia for Minimally Invasive Heart Valve Surgery
The goal of this clinical trial is to evaluate the clinical effects of ultra-fast-track anesthesia (UFTA) for minimally invasive cardiac surgery (MICS) in adults.
- Trial name
- NCT06541483
- Testing
- Ultra-Fast-Track Cardiac Anesthesia(UFTCA), conventional general anesthesia (CGA)
- Volunteers
- 1,200 people
- Sponsor
- Zhejiang Provincial People's Hospital