Clinical trials: Anesthesia, Recovery
Rocuronium, Muscle Weakness
General Anesthesia With and Without Muscle Relaxation and Muscle Strength Recovery
Neuromuscular blocking agents are often used during general anesthesia. Also, general anesthesia may be performed without use of neuromuscular blocking agents.
- Conditions
- Rocuronium, Muscle Weakness, General Anaesthesia
- Trial name
- NCT04760912
- Testing
- Rocuronium, General anesthesia for surgery
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Centre Zagreb
VENTILATION, Capnography
Effects of Capnometry Monitoring in Post Anesthesia Care Unit
There is few information about the best capnometry value in recovery room for intubated awakening patients. Furthermore, capnometry values could influence ventilation applied by nurses on these patients.
- Trial name
- CAPNOSSPI (NCT03370081)
- Testing
- CAPNOGRAPHY
- Where
- France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Bordeaux
Pulmonary Nodules, Lung Neoplasms
Non-intubated Versus Intubated Anesthesia for Thoracoscopic Sublobar Resection
This is a large clinical study that compares two different types of anesthesia for patients undergoing a specific kind of minimally invasive lung surgery (thoracoscopic sublobar resection) to remove small, early-stage lung…
- Conditions
- Pulmonary Nodules, Lung Neoplasms, Thoracic Surgery
- Trial name
- NIVA-TSLR (NCT07395375)
- Testing
- Non-intubated Anesthesia, Conventional Intubated General Anesthesia, Laryngeal Mask Airway (LMA)
- Where
- China
- Volunteers
- 1,600 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Laryngeal Disease, Pharyngeal Diseases
Comparison of Remimazolam and Propofol for Recovery of Ambulatory Upper Airway Surgery
The purpose of this study is to compare the effects of remimazolam and propofol on postoperative recovery time, complications, and safety in patients undergoing ambulatory upper airway surgery under general anesthesia.
- Conditions
- Laryngeal Disease, Pharyngeal Diseases, Oral Cavity Disease, Nasal Disease
- Trial name
- NCT06507202
- Testing
- Remimazolam, Propofol
- Where
- South Korea
- Volunteers
- 116 people
- Sponsor
- Chung-Ang University Gwangmyeong Hospital
Anesthesia
Ilioinguinal/Iliohypogastric Block for Inguinal Hernia Repair
Inguinal hernia have traditionally been done under general anesthesia. While safe, general anesthesia is associated with potential postoperative nausea/vomiting and drowsiness.
- Trial name
- NCT05335837
- Testing
- Regional Anesthesia and Sedation
- Where
- Canada
- Volunteers
- 350 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Anesthesia, Hip Osteoarthritis
The Assessments of the Postoperative Recovery on Elderly Patients Received General Anesthesia or Peripheral Nerve Blocks
Postoperative recovery is always worrisome to the elder patients undergoing Total Hip Replacement (THR). Peripheral Nerve Blocks (PNBs), lumbar plexus block combined with sciatic nerve blocks, may be alterative anaesthesia style…
- Trial name
- NCT01782612
- Testing
- Multimodal analgesic techniques, Total uni-Hip Replacement
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Junle Liu
Postoperative Recovery, Inhalation Anesthesia
Effect of Combined Intravenous-Inhalational Anesthesia (CIVIA) on Postoperative Recovery Patterns.
This study was planned as a single-center, prospective, randomized trial. Adult patients undergoing elective spinal surgery lasting longer than three hours, performed in a neurosurgery operating room, will be evaluated.
- Conditions
- Postoperative Recovery, Inhalation Anesthesia, Total Intravenous Anesthesia
- Trial name
- NCT07123870
- Testing
- Sevofluorane, Desflurane, Total Intravenous Anesthesia(TIVA)
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Anesthesia, Knee Osteoarthritis
The Assessment of Postoperative Recovery in Elder Diabetic Patients
Total Knee Replacement (TKR) performed under general anesthesia is a common successful orthopedic procedure. Nonetheless, in elder patients with diabetes mellitus (DM) this procedure can present unique challenges to orthopedic…
- Trial name
- TKRDM2013 (NCT01871012)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese PLA General Hospital
Adult Patients 19 or Older Scheduled for Elective Arthroscopic Meniscectomy
Comparison of Quality of Recovery Between Remimazolam and Propofol Anesthesia in Patients Undergoing Arthroscopic Meniscectomy
This study aims to compare quality of recovery after surgery and anesthesia between patients undergoing arthroscopic meniscectomy under general anesthesia with either propofol or remimazolam based total intravenous anesthesia.
- Trial name
- NCT05280236
- Testing
- Propofol TIVA, Remimazolam TIVA
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Yonsei University
Atrial Fibrillation, Electric Countershock
BIS-Guided Sedation Versus Standard Clinical Sedation During Elective Electrical Cardioversion for Atrial Fibrillation
Electrical cardioversion (ECV) is a standard procedure used to restore normal heart rhythm in patients with atrial fibrillation (AF) by delivering a brief electrical shock to the heart.
- Conditions
- Atrial Fibrillation, Electric Countershock, Deep Sedation
- Trial name
- BIS-ECV-RCT (NCT07569016)
- Testing
- BIS-guided propofol sedation, Clinical-guided propofol sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Patients Undergoing Elective Craniotomy
Conversion From Total Intravenous Anesthesia Technique to Desflurane Anesthesia for Long Duration Neurosurgery
Since neurological testing during neurosurgery, such as somato-sensory evoked potentials, motor-evoked potentials, auditory evoked potentials and visual evoked potentials are well maintained their wave-form reactivity with total…
- Trial name
- NCT01985854
- Testing
- Propofol, Desflurane
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Tokyo Women's Medical University
Adductor Canal Block, Intrathecal Morphine
The Quality of Recovery After Intrathecal Morphine or Adductor Canal Block in Anterior Cruciate Ligament Reconstruction
The Quality of Recovery 40 (QoR-40) is a multidimensional questionnaire that addresses many aspects of postoperative recovery. The QoR-40 has been used many times to measure the recovery of patients after different surgeries, and…
- Conditions
- Adductor Canal Block, Intrathecal Morphine, Arthroscopic Anterior Cruciate Ligament Reconstruction, Quality of Recovery
- Trial name
- NCT05742958
- Testing
- Intrathecal morphine, Adductor canal block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Cukurova University
Residual Neuromuscular Blockade
Effect of Calcium Chloride on Recovery From Neuromuscular Blockade
The purpose of this study is to evaluate the effect of calcium chloride against residual neuromuscular blockade at the end of general anesthesia
- Trial name
- NCT02213848
- Testing
- Calcium, control
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Seoul National University Hospital
Colorectal Disorders, Postoperative Ileus
Does Epidural Anesthesia Reduce Postoperative Ileus Following Colorectal Surgery?
The use of epidural analgesia (EA) has been suggested as an integral part of an enhanced recovery program for colorectal surgery. However, the effects of EA on postoperative ileus remain controversial.
- Trial name
- NCT04429425
- Testing
- epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Congenital Heart Defect, Congenital Heart Disease
Regional Anesthesia for Cardiothoracic Enhanced Recovery (RACER) Study
The erector spinae plane block is a novel regional anesthetic technique that allows for analgesia of the thorax and abdomen with a peripheral nerve block.
- Conditions
- Congenital Heart Defect, Congenital Heart Disease, Anesthesia, Local, Opioid Use
- Trial name
- NCT03611374
- Testing
- Bilateral Erector Spinae Plane Block (ESPB)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Stanford University
Postoperative Complications
Total Intravenous Anesthesia and Inhalation Anesthesia
The aim of us is to define the incidence of postoperative complications and recovery time in view of two anesthesia procedures. During the period between 01.01.2016 and 01.01.2017, totally 583 patients were included in the study…
- Trial name
- NCT03187717
- Volunteers
- 583 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Pain Management, Colorectal Surgery
Opioid-Free Anesthesia in Colorectal Surgery, 2025 (OFA-CRC-2025)
This study wants to find out if using a pain control method without opioids (Opioid-Free Anesthesia or OFA) works as well as or better than standard anesthesia (which uses opioids) for adults having minimally invasive…
- Conditions
- Pain Management, Colorectal Surgery, Opioid Free Anesthesia, Postoperative Complications
- Trial name
- OFA-CRC-2025 (NCT07771049)
- Testing
- Opioid-Free Anesthesia (OFA), Opioid-Based Anesthesia (OBA)
- Where
- 2 sites in Spain
- Volunteers
- 200 people
- Sponsor
- Hospital Universitario La Fe
Elderly Patients Undergoing Trans Pars Plana Vitrectomy With General Anesthesia
Comparison the Postoperative Quality of Recovery Between Neostigmine and Sugammadex in Elderly Patients Undergoing Trans Pars Plana Vitrectomy With General Anesthesia -Randomized Controlled Trial-
Sugammadex has been approved as the first targeted reversal binding agent providing predictable and complete reversal of neuromuscular blockade induced by rocuronium or vecuronium, and achieving so with a favourable safety…
- Trial name
- NCT03108989
- Testing
- Sugammadex, Neostigmine
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Yonsei University
Laryngectomy; Status
Effect of Dexmedetomidine in Preventing Cough and Postoperative Pain After Laryngeal Surgery for Cancer
Background: During emergence from anesthesia for partial and total laryngectomy, severe airway reflex and systemic hypertension during recovery may lead to pneumoderm, hemorrhage, pneumomediastinum or pneumothorax.
- Trial name
- NCT03918889
- Testing
- Dexmedetomidine Injectable Product, Midazolam injection
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Anesthesia, General
Using the SEDLine for the Titration of Sevoflurane in Elderly Patients Recovery Using the SEDLine TM for the Titration of Sevoflurane in Elderly Patients Undergoing Non-Cardiac Surgery After Beta-Adrenergic Blockade
Asses the effect of the use of Patient State Index (PSI) monitoring on difference in emergence profiles in the elderly (age >65 yrs) population to develop a cost-benefit profile.
- Trial name
- NCT00938782
- Testing
- Sedline
- Where
- 2 sites in United States
- Volunteers
- 67 people
- Sponsor
- Stanford University