Clinical trials: Anesthesia, Recovery
Elective Surgery
Recovery Control Tower Feasibility Pilot
A pilot study in perioperative telemedicine that aims to demonstrate the efficiency, and safety of integrating telemedicine into the PACU environment.
- Trial name
- RCT Pilot (NCT06732921)
- Testing
- Alertwatch - Recovery Control Tower
- Where
- United States
- Volunteers
- 8,500 people
- Sponsor
- Washington University School of Medicine
Anesthesia, Intravenous, Pain, Postoperative
Virtual Reality in the Operating Room
This is a randomized, controlled trial designed to investigate whether the use of virtual reality immersive relaxation during hand/arm operations can allow for a relaxing operating room experience for patients while potentially…
- Conditions
- Anesthesia, Intravenous, Pain, Postoperative, Delayed Recovery From Anesthesia, Satisfaction
- Trial name
- OR-VR (NCT03614325)
- Testing
- Virtual Reality Immersive Relaxation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Beth Israel Deaconess Medical Center
Breast Cancer
The Effect of Ultrasonography-guided Fascial Plane Blocks in Breast Cancer Surgery Patients
The aim of this study was to evaluate the efficacy of serratus anterior plane (SAP) block, pectoserratus plane (PECS II) block, and erector spinae plane (ESP) block on postoperative acute pain, quality of recovery and chronic…
- Trial name
- NCT06419504
- Testing
- SAP block group, PECS II block group, ESP block group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Antalya Training and Research Hospital
Anesthesia, Analgesia
Preoperative Dexamethasone to Improve Quality of Recovery After Laparoscopic Bariatric Surgery
In the obese patient, adequate pain relief in the postoperative period is an important parameter that affects patient comfort and hospital stay.
- Conditions
- Anesthesia, Analgesia, Acute Pain
- Trial name
- NCT05752734
- Testing
- Group D, Group C
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Hip Fracture
Peripheral Nerve Blocks in Elderly Patients With Hip Fracture
As the population ages, the frequency of surgery is increasing proportionally, bringing with it the challenge of managing older patients with frequent comorbid diseases and an increased risk of complications.
- Trial name
- NCT02635763
- Testing
- Femoral nerve and the lateral cutaneous nerve block, Lumbar plexus and sacral plexus nerve block
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Uterine Bleeding, Uterine Neoplasms
Anterior Quadratus Lumborum Block as a Component of Multimodal Analgesia for Abdominal Hysterectomies
The main goal of this randomised double-blinded controlled trial is to assess whether adding anterior quadratus lumborum block preoperatively can reduce intraoperative and postoperative opioid consumption, reduce pain after…
- Conditions
- Uterine Bleeding, Uterine Neoplasms, Uterine Diseases, Uterine Fibroids
- Trial name
- NCT07046949
- Testing
- ANTERİOR QUADRATUS LUMBORUM BLOCK, Parenteral administration of analgesics, General Anesthesia (GA)
- Where
- Ukraine
- Volunteers
- 56 people
- Sponsor
- Yuri Semenyuk Rivne Regional Clinical Hospital
Elective Surgeries
Postoperative Quality of Recovery in Patients Receiving Anaesthesia
The investigator's study is designed to evaluate the recovery of patients receiving anaesthesia for surgeries; in different domains like the physiological, nociceptive, cognitive and emotional to the participants' preoperative…
- Trial name
- NCT03535025
- Where
- Nepal
- Volunteers
- 195 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Systemic Inflammatory Response Syndrome
Can Biomarkers Aid in the Prediction of Postoperative Pain and Circulatory Instability After Major Abdominal Surgery?
Patients undergoing major surgery are exposed to extensive damage of tissues, which induces widespread activation of the inflammatory system, called 'systemic inflammatory response syndrome' (SIRS).This activation of the…
- Trial name
- NCT02563652
- Where
- 2 sites in Italy, Norway
- Volunteers
- 101 people
- Sponsor
- St. Olavs Hospital
Ischaemic Heart Disease, Aortic Stenosis
Remifentanil/Sufentanil for CABG+/-AVR Evaluated by Recovery, Cognitive Function, Haemodynamics and Biochemical Markers.
To evaluate the effect on cognitive function, recovery, cardioprotection and haemodynamics of standard Remifentanil anaesthesia to standard Sufentanil anaesthesia in patients undergoing coronary artery bypass with or without…
- Trial name
- PRECON2 (NCT02053818)
- Testing
- Remifentanil, Sufentanil
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital
Anaesthesia
Aminophylline and Cognitive Function After Sevoflurane Anaesthesia
Early postoperative recovery of neurologic and cognitive functions is especially advantageous after fast-tracking ambulatory procedures to hasten home discharge after surgery.1 It is well known that volatile anaesthetic agents…
- Trial name
- NCT01022151
- Testing
- 0.2 mL/kg of aminophylline 10 mg/mL [group A2], 0.2 mL/kg of aminophylline 15 mg/mL [group A3], 0.2 mL/kg of aminophylline 20 mg/mL [group A4]
- Where
- Saudi Arabia
- Volunteers
- 180 people
- Sponsor
- King Faisal University
Cystoscopes, Baxter Anaesthesia Brand of Desflurane
Comparing Desflurane to Sevoflurane for the Effect on Recovery Time in Patients Undergoing Urological Cystoscope Surgery
This is a single-center, prospective, randomized, double-blind, double-arm trial including 68 subjects scheduled to undergo urological cystoscope surgeries under general anesthesia (GA) with intubation through a laryngeal mask…
- Conditions
- Cystoscopes, Baxter Anaesthesia Brand of Desflurane, Sevoflurane
- Trial name
- NCT01219881
- Testing
- Desflurane, Sevoflurane
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Osteo Arthritis Knee and Hip, Osteo Arthritis
General Anaesthesia vs Spinal Anaesthesia: Patient Outcomes and Success in Outpatient Primary Total Knee and Hip Arthroplasty
Total knee arthroplasty (TKA) and total hip arthroplasty (THA) are common operations used to treat severe joint disease, most often caused by osteoarthritis.
- Conditions
- Osteo Arthritis Knee and Hip, Osteo Arthritis, Inflammatory Joint Disease (IJD)
- Trial name
- GASPS (NCT07334132)
- Testing
- General Anaesthesia, Spinal Anesthesia (bupivacaine)
- Volunteers
- 600 people
- Sponsor
- Region Örebro County
Anesthesia Recovery Period, Postoperative Complications
The Anesthesia Effects of Dexmedetomidine Combined With Desflurane or Propofol in Lobectomy
In one-lung ventilation surgery, compared with dexmedetomidine combined with propofol, dexmedetomidine combined with desflurane may be beneficial to accelerate patients' recovery and reduce postoperative pulmonary complications…
- Trial name
- NCT06207344
- Testing
- Dexmedetomidine and propofol, Dexmedetomidine and desflurane
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Regional Anesthesia Morbidity, Pain, Postoperative
Efficacy of Ultrasound Guided ESP Vs Video-assisted PVB Catheter Placement in Minimally Invasive Thoracic Surgery
Minimally Invasive Thoracic Surgery (MITS) is a surgical method used to perform lung surgery through small incisions between the ribs and includes both Video-Assisted Thoracic Surgery (VATS) and Robotic assisted Thoracic Surgery…
- Conditions
- Regional Anesthesia Morbidity, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT04729712
- Testing
- Anaesthesiologist-administered ultrasound guided Erector Spinae block with catheter insertion, Surgeon-administered video-assisted Paravertebral block with catheter insertion
- Where
- 2 sites in Ireland
- Volunteers
- 80 people
- Sponsor
- Mater Misericordiae University Hospital
Shoulder Arthroscopy
Comparison of Postoperative Quality of Recovery by Anesthetic Method in Patients Undergoing Shoulder Arthroscopy
The aim of this study is to compare the quality of recovery in patients undergoing arthroscopic shoulder surgery depending on the type of anesthesia used: 1.
- Trial name
- NCT06638112
- Testing
- Brachial Plexus Block, General Anesthesia (control group)
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Seoul National University Hospital
Postoperative Nausea and Vomiting
The Impact of Preoperative Olanzapine on Quality of Recovery After Discharge From Ambulatory Surgery
The primary objective of this phase 2 randomized controlled trial is to determine whether the pre-operative administration of olanzapine (5 mg PO) improves quality of recovery (assessed by the Quality of Recovery-40 (QoR-40)…
- Trial name
- NCT05676294
- Testing
- Olanzapine
- Where
- United States
- Volunteers
- 398 people
- Sponsor
- Yale University
Inguinal Hernia Unilateral, Postoperative Pain
Quadro-Iliac Plane Block for Postoperative Analgesia in Laparoscopic Inguinal Hernia Repair
The goal of this randomized controlled trial is to learn whether an ultrasound-guided quadro-iliac plane block (QIPB) reduces opioid use and pain after laparoscopic inguinal hernia repair in adults aged 18-65 years.
- Conditions
- Inguinal Hernia Unilateral, Postoperative Pain, Opioid Use
- Trial name
- QIPB-LIHR (NCT07878936)
- Testing
- Quadro-iliac plane block
- Volunteers
- 64 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
General Anesthesia, Surgeries Requiring A Minimum One Day Hospitalization
How Lidocaine Affects Outcomes In Orthopedic Surgery Patients
This study will evaluate the effect of intraoperative lidocaine infusion on postoperative orientation and concentration in elderly patients having general anesthesia for orthopedic surgeries requiring a minimum 2 days…
- Conditions
- General Anesthesia, Surgeries Requiring A Minimum One Day Hospitalization, Elderly
- Trial name
- NCT01179100
- Testing
- Lidocaine
- Where
- United States
- Sponsor
- Cedars-Sinai Medical Center
Pupillary Reflex Impaired
Effects of Different Types of General Anesthesia on Postoperative Pupillary Reactivity
Objective: To compare the effects of volatile and intravenous anesthetics on pupillary function after general anesthesia using a portable infrared pupillometer. Design: A monocentric, prospective, double blinded randomized study.
- Trial name
- NCT04307238
- Testing
- PLR, Alertness testing, Propofol anesthesia
- Where
- Austria
- Volunteers
- 108 people
- Sponsor
- Medical University of Vienna
Pituitary Adenoma
Comparison of Postoperative Recovery of Sevoflurane and Propofol After Transsphenoidal Surgery
Currently, total intravenous anesthesia (TIVA) and inhaled anesthesia are both commonly used for transsphenoidal pituitary adenoma resection.
- Trial name
- NCT05822817
- Testing
- sevoflurane, propofol
- Where
- China
- Volunteers
- 252 people
- Sponsor
- Peking Union Medical College Hospital