Clinical trials: Anesthesia, Recovery
Anesthesia Emergence Delirium
Effect Of Combination of Morphine+Fentanyl on Emergence Delirium in Patients of Cleft Lip and Palate Repair
Emergence Delirium And Recovery Profile In Patients Undergoing Cleft Lip And Cleft Palate Repair With Either Combination Of Morphine Plus Fentanyl Or Fentanyl Alone
- Trial name
- NCT03010540
- Testing
- MORPHINE PLUS FENTANYL, Fentanyl
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Residual Neuromuscular Block
Neostigmine Reversal And Neuromuscular Recovery
Patients undergoing surgery often receive paralytic agents (or neuromuscular blocking agents (NMBAs)) to facilitate the procedure. At the end of surgery, the effects NMBAs are reversed with a drug called neostigmine.
- Trial name
- NCT02433808
- Testing
- Neostigmine Group, No Neostigmine group
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Pain
Comparison of Ultrasound and Nerve Stimulation Technique for Continuous Sciatic Nerve Block
The most useful method to manage pain after major foot and ankle surgery is infusion of local anesthetic with a catheter close to the sciatic nerve in the popliteal space above the knee joint.
- Trial name
- NCT00497276
- Testing
- placement of popliteal catheter
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Enhanced Recovery After Surgery, Anesthesia
Enhanced Recovery After Surgery Protocol on Early Mobilization After Colorectal Surgery
Early mobilization is an important factor in increasing postoperative colorectal surgeries outcome. There are four components held by anesthesiologist in Enhanced Recovery After Surgery protocol for colorectal surgery in our…
- Conditions
- Enhanced Recovery After Surgery, Anesthesia, Surgery-Complications, Colorectal
- Trial name
- NCT06065696
- Testing
- Early mobilization, No early mobilization
- Where
- Indonesia
- Volunteers
- 343 people
- Sponsor
- Universitas Indonesia
End-stage Lung Disease
BREATHE Study: Spontaneous Breathing-Preserved Anesthesia and Surgical Strategy for Hospital Recovery in Lung Transplantation
The goal of this study is to learn whether a spontaneous-breathing ("tubeless") anesthesia and surgery strategy can improve early recovery and remain safe for adults who receive a lung transplant.
- Trial name
- BREATHE-LTx (NCT07384546)
- Testing
- Lung transplantation that preserves spontaneous breathing function
- Volunteers
- 110 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Low-flow Anesthesia
High vs. Low Flow Sevoflurane Anesthesia in Pediatric Laparoscopic Surgery: Recovery, Hemodynamics, and Cost Comparison
The primary objective of our study is to compare the effects of different flow rates of the routinely used inhalation agent, sevoflurane, on postoperative recovery times in pediatric patients undergoing elective laparoscopic…
- Trial name
- NCT06676969
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Anesthesia, Recovery
Reduction in Sedation: Colonoscopy vs Esophagoduodenoscopy First
The purpose of this research is to compare the effect of different procedural sequences on the time to recovery and the propofol sedation requirements in patients undergoing bidirectional endoscopy with sedation.
- Trial name
- RECoVER (NCT04096339)
- Testing
- Colonoscopy followed by EGD, EGD followed by Colonoscopy
- Where
- Lebanon
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Recovery From Anesthesia
Improved Patient Recovery After Anesthesia
The proposed study will measure the incidence of adverse events and the decrease in time to meet discharge criteria from the post anesthesia care unit when hypercapnic and hyperpnoea are used during emergence.
- Trial name
- NCT01477398
- Testing
- QED-100
- Volunteers
- 31 people
- Sponsor
- University of Utah
Coughing Responses at Tracheal Extubation
Comparison of the Effects of Oxycodone Versus Fentanyl on Airway Reflex to Tracheal Extubation and Postoperative Pain
This study was performed to compare the effects of oxycodone and fentanyl on airway and hemodynamic responses and postoperative pain during recovery period in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT03204045
- Testing
- fentanyl, Oxycodone, control
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Yeungnam University College of Medicine
Ventilatory Depression, Postoperative Respiratory Failure
Hyperoxia on Ventilation During Recovery From General Anesthesia
In this preliminary, crossover investigation the investigators will examine the effect of oxygen supplementation on the recovery of breathing in the immediate post-anesthesia period.
- Trial name
- NCT05922020
- Testing
- Oxygen gas
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Pain, Postoperative, Anesthesia
Transversus Abdominal Plane Block at Total Laparoscopic Hysterectomy: Effect on Quality of Recovery
The Transversus Abdominal Plane (TAP) block has been used with good success to decrease postoperative pain following laparatomy.
- Trial name
- TAP (NCT01479270)
- Testing
- TAP Block
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Opioid Free Anesthesia
Intraoperative Retrolaminar Block as Opioid Free Anesthesia After Posterior Lumber Spine Discectomy
Opioid-free intraoperative protocols have been successfully used in specific surgical populations with equal or superior results to classic general anesthetic approaches.
- Trial name
- NCT05312866
- Testing
- Standard analgesia (paracetamol +fentanyl), Retrolaminar block with bupivacaine + magnesium sulfate + dexamethasone
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Opioid Free Anesthesia, Laparoscopic Bariatric Surgeries
Opioid Free Anesthesia Versus Opioid Based Anesthesia
This Study aims to evaluate the efficacy of opioid free general anesthesia in achieving enhanced recovery after surgery (ERAS) in laparoscopic bariatric surgery in terms of post-operative recovery time, cumulative pethidine…
- Trial name
- NCT06650371
- Testing
- Fentanyl infusion, Dexamedomedine and ketamine infusion
- Volunteers
- 36 people
- Sponsor
- Ain Shams University
Anesthesia, Anesthesia; Reaction
Comparison of Hyperbaric Prilocaine 2% 50 Mg and Hyperbaric Bupivacaine 0.5% 12.5 Mg Against Spinal Anesthesia Recovery Time in Cystoscopy Procedure
Data regarding the comparison of recovery time from spinal anesthesia between prilocaine and bupivacaine are still relatively limited.
- Trial name
- NCT05610007
- Testing
- Prilocaine
- Where
- Indonesia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Anesthesia, Anesthesia; Adverse Effect
Comparison of an Opioid-Free Anesthesia Protocol Versus Standard Practices on Early and Late Post-operative Recovery
Opioid-Free Anesthesia (OFA) is an anesthesia protocol that does not use morphine, and is increasingly used routinely. Indeed, this protocol would theoretically allow a better post-operative analgesic control, a lower incidence…
- Conditions
- Anesthesia, Anesthesia; Adverse Effect, Opioid Analgesic Adverse Reaction, Post-Op Complication
- Trial name
- SOFA (NCT04797312)
- Testing
- Opioid Free Anaesthesia protocol, standard practice protocol based on the use of opioids (sufentanil or remifentanil)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Angers
Surgery, Anesthesia
Propofol Versus Sevoflurane Recovery After Gynecological Surgery
80% of 25 million American who undergo surgery describe moderate to severe pain. The use of multimodal analgesic techniques can attenuate patient's postoperative pain and several different medication have been found to be…
- Trial name
- NCT01755234
- Testing
- Sevoflurane, Propofol
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Northwestern University
Uterine Fibroids (UF)
Ultrasound-Guided Stellate Ganglion Block Plus Propofol for Perimenopausal Insomnia With Anxiety
Laparoscopic myomectomy is a commonly performed minimally invasive gynecologic procedure. However, surgical trauma, tracheal intubation, and pneumoperitoneum may induce pronounced perioperative stress responses, resulting in…
- Trial name
- SGB-PROP-PIA (NCT07384468)
- Testing
- Ultrasound-Guided Stellate Ganglion Block
- Where
- China
- Volunteers
- 233 people
- Sponsor
- Xiaochen Ji
Motility Function
Esophageal Manometry During Recovery From Anesthesia: Pilot Study
1. An intact pharyngoesophageal reflex is essential to protect the upper airway from aspiration of either mouth contents or regurgitated gastric refluxate. This reflex is essential at protecting the airway in all patients. 2.
- Trial name
- EMAP (NCT02661386)
- Testing
- Motility Procedure
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Gynecologic Disease
the Effect of Opioid-free General Anesthesia
This study is performed to investigate the effect of opioid-free general anesthesia on the recovery quality after gynecological laparoscopy.
- Trial name
- NCT04409964
- Testing
- Dexmedetomidine Hydrochloride, Lidocaine Hydrochloride, Remifentanil Hydrochloride
- Where
- 2 sites in South Korea
- Volunteers
- 78 people
- Sponsor
- The Catholic University of Korea
Anesthesia Outcomes, Anesthesia Complication
Does Style of Pre-sedation Instructions Improve Patient Outcomes in Ambulatory Anesthesia for Oral and Maxillofacial Surgery?
This randomized controlled trial aims to evaluate the impact of a brief guided visualization exercise on anesthesia-related outcomes in oral and maxillofacial surgery in patients scheduled for ambulatory anesthesia in the oral…
- Conditions
- Anesthesia Outcomes, Anesthesia Complication, Anesthesia and Procedure Related Time Intervals, Anesthesia Recovery Period
- Trial name
- NCT06768021
- Testing
- Guided visualization and standardized pre-sedation instructions, Standardized pre-sedation instructions only
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Alameda Health System