Clinical trials: Anesthesia, Recovery
Residual Neuromuscular Block
Impact of Sugammadex Versus Neostigmine on Early Postoperative Pulmonary Function
Residual neuromuscular blockade (NMB) after general anesthesia increases the risk of postoperative respiratory complications (atelectasis, pneumonia, re-intubation) and delays pulmonary function recovery.
- Trial name
- NCT07309393
- Testing
- Sugammadex, Neostigmine
- Where
- 3 sites in China
- Volunteers
- 240 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Postoperative Recovery, Pediatric Anesthesia
Timing of Aminophylline and Recovery in Pediatric Ambulatory Surgery
Beyond its established use as a bronchodilator and therapy for apnea of prematurity, aminophylline has demonstrated utility in reversing the effects of anesthetics, enhancing recovery by accelerating respiratory and cognitive…
- Conditions
- Postoperative Recovery, Pediatric Anesthesia, Ambulatory Surgery
- Trial name
- ELEAR-PAP (NCT07011134)
- Testing
- Group (E): receive aminophylline early intraoperatively,, Group (L) received aminophylline late intraoperatively, Group (C) will receive normal saline post-anesthetic discontinuation.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Hany Mohammed El-Hadi Shoukat Mohammed
Total Hip Arthroplasty (THA), Femoral Neck Fractures
PNB Anesthesia Improves Older Patients' Postoperative Early Recovery Outcomes After Total Hip Arthroplasty
Early postoperative rehabilitation is an important issue for total hip arthroplasty, especially in older patients. This retrospective clinical trial is to assess the impact of peripheral nerve block anesthesia versus general…
- Trial name
- NCT07163598
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 516 people
- Sponsor
- RenJi Hospital
Remazolam Anesthesia, Postoperative Recovery
Effect of Remazolam on Anesthesia Recovery in Patients Undergoing Fundus Surgery
to investigate the effect of remazolam benzenesulfonate in patients with ocular fundus surgery, so as to guide clinical anesthesiologists to choose more appropriate anesthetic drugs in fundus surgery
- Trial name
- NCT06205719
- Testing
- ciprofol, Remazolam, Flumazenil
- Volunteers
- 93 people
- Sponsor
- Sichuan Provincial People's Hospital
Bariatric Surgery Candidate
The Impact of Moderate Versus Deep Neuromuscular Blockade on Enhanced Recovery After Bariatric Anesthesia
Most published articles suggest that deep neuromuscular blockade is required for bariatric surgery. However, the evidence for such practice is still inconclusive.
- Trial name
- NCT04466943
- Testing
- Neuromuscular transmission monitoring (NMT)
- Where
- Saudi Arabia
- Volunteers
- 110 people
- Sponsor
- King Saud University
Flap Monitoring, Inflammation
Effect of Dexmedetomidine on Microsurgery Reconstruction in Cancer Patient
This double-blinded randomized controlled trial aims to investigate the effect of intraoperative dexmedetomidine administration on early flap viability and microvascular integrity in cancer patients undergoing elective…
- Conditions
- Flap Monitoring, Inflammation, Thrombosis, Oxidative Stress
- Trial name
- DEXFLAP (NCT06993740)
- Testing
- NaCl 0,9%, Dexmedetomidine
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Dharmais National Cancer Center Hospital
General Anesthesia
Clinical and Genetic Factors on the Postoperative Recovery Time of General Anaesthesia
To evaluate the effect of clinical factors on the recovery time of postoperative anesthesia and the effect of genetic variation in gDNA on the recovery time of postoperative anesthesia.
- Trial name
- NCT02822417
- Where
- China
- Volunteers
- 1,453 people
- Sponsor
- Yijing He
Failed Moderate Sedation During Procedure
The Effects of Single-dose Rectal Midazolam Application on Post-operative Recovery
This study aimed to compare the efficiency of rectal midazolam addition after applying bupivacaine and caudal anesthesia on postoperative analgesia time, the need for additional analgesics, postoperative recovery, sedation, and…
- Trial name
- NCT02127489
- Testing
- 1 mL/kg bupivacaine 0.25%.
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Karadeniz Technical University
ERAS
Effect of Regional Anesthesia on Enhanced Recovery After Spine Surgeries
This study will be carried out on 80 patients who will be presented for different spine surgeries under general anesthesia and regional anesthesia technique in Tanta university hospitals.
- Trial name
- NCT04586257
- Testing
- Erector spinae plane block, Throacolumbar interfacial plane block
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Tanta University
Breast Cancer, Pain, Acute
ESP in Breast Surgery Due to Cancer
Patients scheduled for breast surgery due to cancer. Each patient will be treated with intravenous (i.v.) oxycodone - patient-controlled analgesia (PCA).
- Conditions
- Breast Cancer, Pain, Acute, Anesthesia, Local
- Trial name
- NCT04726878
- Testing
- Erector spinae plane block, General anesthesia, Patient-controlled analgesia
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- Medical University of Lublin
Restlessness, Pain
Effects of Dexmedetomidine on Stress Response and Postoperative Analgesia
Dexmedetomidine is a highly selective α2 adrenoreceptor agonist approved by the US FDA for short-term postoperative sedation and analgesia.It can also reduce the stress response without respiratory depression.
- Trial name
- NCT01517932
- Testing
- dexmedetomidine
- Volunteers
- 60 people
- Sponsor
- Fang Luo
Perioperative Diaphragmatic Function
Using Diaphragm Ultrasonography, Sugammadex Recovers Diaphragmatic Function More Effectively Than Neostigmine.
The aim of our study is to assess differences in the recovery of muscle function, using diaphragm ultrasonography, after reversal of a rocuronium-induced block, using neostigmine versus sugammadex
- Trial name
- NCT06982092
- Testing
- sugammadex, Neostigmine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain, Postoperative, Pain, Acute
Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine
The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective laparoscopic…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Neuropathic
- Trial name
- NCT04858711
- Testing
- ketamine-lidocaine-dexmedetomidine, fentanyl
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aretaieion University Hospital
Pain
Supraclavicular Versus Interscalene Block for Shoulder Surgery
The purpose of this study is to compare the supraclavicular block to interscalene block in patients undergoing arthroscopic shoulder surgery.
- Trial name
- NCT02486549
- Testing
- Supraclavicular Block, Interscalene Block, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Tokat Gaziosmanpasa University
Living Donor Hepatectomy
Perioperative Epidural Anesthesia and Analgesia on Gut Microbiota
As the only curative treatment for end-stage liver diseases, liver transplantation has been widely carried out around the world.
- Trial name
- NCT04079673
- Testing
- Patient controlled epidural analgesia, Intravenous patient controlled analgesia
- Where
- Taiwan
- Volunteers
- 42 people
- Sponsor
- National Taiwan University Hospital
Perioperative Hypothermia, Total Knee Arthroplasty
Forced-Air Warming for Preventing Perioperative Hypot
Perioperative hypothermia is a common complication during total knee arthroplasty (TKA) and may increase the risk of shivering, delayed anesthetic recovery, and postoperative complications.
- Trial name
- NCT07613203
- Testing
- Forced-Air Warming, Routine Passive Warming
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Shanghai 6th People's Hospital
Unruptured Cerebral Aneurysm
Identification of Genetic Polymorphisms Related to Propofol Requirement and Recovery Through Genome-wide Association Study (GWAS) in Total Intravenous Anesthesia for Clipping of Unruptured Cerebral Aneurysm in Korean Population
In neurosurgical anesthesia, propofol based total intravenous anesthesia (TIVA) is frequently used due to brain relaxation and less effect on electrophysiologic monitoring.
- Trial name
- NCT03087383
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Yonsei University
Deep Sedation, Ambulatory Surgery
Effects Of Propofol-Dexmedetomıdıne And Propofol- Remıfentanıl In Hysteroscopıc Operations.
In our study, the investigators aimed to compare the effects of dexmedetomidine-propofol and remifentanil-propofol combinations on perioperative spontaneous respiration, hemodynamics, recovery, participants, surgeon and…
- Conditions
- Deep Sedation, Ambulatory Surgery, Ambulatory Surgical Procedure
- Trial name
- NCT05674201
- Testing
- Propofol-Dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Siirt Training and Research Hospital
Neuromuscular Blockade, Surgery
Effect of Neuromuscular Blockade on Operating Conditions and Overall Satisfaction During Spinal Surgery
The investigators aim to investigate operating conditions, postoperative recovery and overall satisfaction of surgeons between deep neuromuscular blockade (NMB) group and restricted NMB group during spinal surgery under general…
- Conditions
- Neuromuscular Blockade, Surgery, Anesthesia, Spinal Diseases
- Trial name
- NCT02724111
- Testing
- sufficient dose of rocuronium, sugammadex 10 min after position change
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Korea University Guro Hospital
Diabetes Mellitus, Glycemic Control
Effect of Glycemic Control on Intraoperative NIRS and Postoperative Recovery in Diabetic Patients
This prospective observational study aims to evaluate the effect of glycemic control level on intraoperative cerebral oxygenation measured by near-infrared spectroscopy (NIRS) and postoperative recovery in patients with diabetes…
- Conditions
- Diabetes Mellitus, Glycemic Control, Cerebral Oxygenation, Anesthesia
- Trial name
- NIRS-DM (NCT07491185)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ege University