Clinical trials: Anesthesia, Recovery
Postoperative Pain, Laparoscopic Cholecystectomy
Erector Spinae Plane Block and Low-Flow Anaesthesia in Laparoscopic Cholecystectomy
This prospective randomized controlled study aims to evaluate the effects of preoperative ultrasound-guided erector spinae plane (ESP) block combined with low-flow anaesthesia on postoperative quality of recovery and opioid…
- Trial name
- NCT07653490
- Testing
- Erector Spinae Plane Block, Low Fresh Gas Flow (0.5 L/min), Standard Fresh Gas Flow (3 L/min)
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Taksim Egitim ve Arastirma Hastanesi
Hepatectomy
Effects of Propofol on Oxidative Stress and Liver Regeneration After Partial Hepatectomy
Propofol is an anaesthetic agent that showed in vitro and in vivo anti oxidant properties. No data are available concerning the potential benefit of a total anaesthesia with propofol in partial hepatic surgery.
- Trial name
- NCT00219856
- Testing
- Propofol, Penthotal, Desflurane
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Rennes University Hospital
Anaesthesia
"Light" Versus "Deep" Bispectral Index (BIS) Guided Sedation for Colonoscopy
In this trial, patients undergoing elective colonoscopy under sedation will be randomised to BIS-guided sedation targeting either "light" (bispectral index [BIS] 70-80) or "deep" (BIS<60) sedation.
- Trial name
- NCT01457274
- Testing
- Sedation depth
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Melbourne Health
Abdominal Muscles/Ultrasonography, Adult
TAP Catheters Versus Intrathecal Morphine for Cesarean Section
Morphine, when given as part of spinal anesthesia, is associated high incidence of nausea and pruritus, which may affect quality of recovery.
- Conditions
- Abdominal Muscles/Ultrasonography, Adult, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage
- Trial name
- NCT01593280
- Testing
- TAP catheter, intrathecal morphine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stamford Anesthesiology Services, PC
Acute Abdomen, Abdominal Trauma
Enhanced Recovery After Surgery (ERAS) in Patients Undergoing Emergency Laparotomy
The goal of this clinical trial is to test the safety and effectiveness of the ERAS protocols compared to a conventional care protocols in patients who received emergency laparotomy.
- Conditions
- Acute Abdomen, Abdominal Trauma, Emergency Surgery
- Trial name
- ERAS (NCT06182488)
- Testing
- ERAS protocols, Conventional protocols
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Tianjin Medical University
Short Stature, Osteoarthritis
Effect of Anesthesia on Quality of Recovery in Patients Undergoing Correctional Tibial Osteotomy - A Randomized Controlled Trial
The effect of total intravenous anesthesia (TIVA) versus inhalational anesthesia on the quality of recovery from surgery has been reported in several different types of operations.
- Trial name
- NCT02826902
- Testing
- propofol and remifentanil, desflurane and remifentanil
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Yonsei University
Anesthesia Recovery
Airway Complications After LMA in Children
Background: The removal of Laryngeal Mask Airway (LMA) in children may be associated with respiratory adverse events. The incidence of these adverse events may be influenced by the type of anesthesia maintenance.
- Trial name
- NCT03553082
- Testing
- Sevoflurane, Propofol
- Where
- Lebanon
- Volunteers
- 135 people
- Sponsor
- American University of Beirut Medical Center
The Upper Esophageal Sphincter Contraction Strength
ERAS Swallowing Rehabilitation in Elder Patients
The investigators studied that swallowing function of patients receiving the Early Recovery Accelerated Swallowing (ERAS-W program) training will recover fast than that of patients in the control group.
- Trial name
- NCT05999786
- Testing
- early rehabiliation swallowing program, not receiving early rehabilitation swallowing program
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Pain
Comparison of US-Guided Paravertebral and Proximal Intercostal Nerve Blocks
The purpose of this study is to compare the proximal intercostal block to the more medial (classic) ultrasound-guided paravertebral block.
- Trial name
- NCT02911168
- Testing
- Proximal Intercostal Block, Paravertebral Block
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Residual Neuromuscular Blockade
Electromyographic Assessment of Onset and Recovery of Neuromuscular Blockade
Residual neuromuscular blockade (weakness) is a common occurrence in the postanesthesia care unit when muscle relaxant drugs have been used in the operating room.
- Trial name
- NCT01678625
- Testing
- Train-of-four ratio calculation (T4-EMG)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Endeavor Health
Anesthesia, Intravenous, Anesthesia Recovery Period
Effects of Hypercapnia on Emergence From General Anesthesia Under Propofol
Hypercapnia derives increase of cerebral blood flow and cardiac output. It means that the rate of propofol elimination from the brain and the blood will be increased and the patient will awake more quickly.
- Trial name
- NCT01531491
- Testing
- Rebreathing tube, No rebreathing tube (Nothing)
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- DongGuk University
Surgery
Study of Recovery of Strength After Surgery Comparing Two Different Medications for Reversal of Muscle Relaxant
The purpose of this study is to compare two different medications (neostigmine/glycopyrrolate and sugammadex) to see if one drug improves patient comfort regarding the return of muscle strength after surgery.
- Trial name
- NCT03116997
- Testing
- Neostigmine+glycopyrrolate, Sugammadex
- Where
- 4 sites in United States
- Volunteers
- 201 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Residual Neuromuscular Blockade
Comparison of the ToFscan and TetraGraph During Recovery of Neuromuscular Function in the Post Anesthesia Care Unit
The aim of this investigation is to compare the performance of two quantitative monitors utilized on post-anesthesia recovering patients.
- Trial name
- NCT03920670
- Testing
- TetraGraph (TG), ToFscan (TS)
- Where
- 3 sites in United States, Hungary
- Volunteers
- 120 people
- Sponsor
- Mayo Clinic
Anesthesia
Comparative Study of Recovery Characteristics Between Remimazolam Anesthesia With Flumazenil and Desflurane Anesthesia for Closed Reduction of Nasal Bone Fracture
The goal of this prospective, randomized study is to compare recovery characteristics between remimazolam anesthesia with flumazenil and desflurane anesthesia in patients undergoing closed reduction of nasal bone fracture.
- Trial name
- NCT05774366
- Testing
- Remimazolam, Desflurane
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Daegu Catholic University Medical Center
Cardiac Disease
Opioid Reduced Anesthesia With Parasternal CATheters on Postoperative Delirium After Cardiac Surgery
PostOperative Delirium (POD) is the most common neuropsychiatric complication following cardiac surgery and may be related to morphine consumption.
- Trial name
- ORACAT (NCT05880615)
- Testing
- collection of datas
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Regional Anesthesia Morbidity
Efficacy of SAP Block Versus ESP Block in VATS Surgery
During VATS (Video assisted thoracic surgery) small incisions are made in the patient's chest through which a camera and instruments are inserted to allow a lung operation to be performed.
- Trial name
- ESPvSAP (NCT03862612)
- Testing
- regional anaesthesia with Levobupivicaine 0.25% 30mls with two methods either erector spinae plane block or serratus anterior plane block
- Where
- Ireland
- Volunteers
- 60 people
- Sponsor
- Mater Misericordiae University Hospital
Postoperative Pain Management in Total Knee Arthroplasty
Dexmedetomidine as an Adjunct to Periarticular Ropivacaine in Total Knee Replacement: A Pilot Randomised Controlled Trial
This study aims to evaluate whether adding dexmedetomidine to ropivacaine-based periarticular infiltration (PAI) improves postoperative pain control in patients undergoing total knee replacement (TKR).
- Trial name
- NCT07176065
- Testing
- Ropivacaine + saline solution, Ropivacaine + Dexmedetomidine
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- University of Malaya
Effect of General Anesthetic Dose on Recovery From Surgery
The BALANCED Anaesthesia Study
General anaesthesia is a reversible drug-induced coma. Too little can result in patients being partially conscious during surgery; too much can slow recovery after surgery.
- Trial name
- NCT02073357
- Testing
- Light general anaesthesia (BIS = 50), deep general anaesthesia (BIS = 35)
- Where
- United States
- Sponsor
- The Cleveland Clinic
Anesthesia, Surgery
Hypercapnic Spontaneous Hyperpnoea and Recovery From Sevoflurane Anesthesia
The rate of elimination of inhalation agent is directly proportional to the degree of alveolar ventilation. Using Isocapnic Hyperpnoea (IH) device, it is possible to maintain constant end-tidal CO2 with increased minute…
- Trial name
- NCT01151267
- Testing
- Standard Anesthesia management for post surgical patients, Hypercarbic Spontaneous Hyperpnoea
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University Health Network, Toronto
Clinical Decision Support System
Pre-anesthesia Imaging-based Respiratory Assessment and Analysis
This study is to establish a preoperative respiratory imaging assessment database and develop a difficult intubation risk prediction model and further risk analysis.
- Trial name
- NCT06270797
- Testing
- intubation for general anesthesia
- Where
- Taiwan
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital