Clinical trials: Anesthesia, Recovery
Bidirectional Endoscopy
Single Center Open Prospective Study for the Comparison of Procedural Sequence in Same Day Consecutive Bidirectional Endoscopy
The investigators study aim is to determine whether there is a any advantage in starting with upper or lower endoscopy. The main study objective will be the amount of analgesia needed for sustaining the examinee's comfort during…
- Trial name
- NCT01491126
- Where
- Israel
- Volunteers
- 170 people
- Sponsor
- Sheba Medical Center
Pain, Anesthesia
NoL and BIS Monitoring on Patients Recovery and Safety After Surgery
So far, only vital signs (mostly, blood pressure and heart rate) helped the anesthesiologist to administer hypnotic agents or analgesics.
- Trial name
- CINAAMON (NCT03410485)
- Testing
- BIS index/NoL index, Variation of baseline mean arterial pressure
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Pain Management, Perioperative Analgesia
From Battlefield to Recovery: Continuous Regional Anaesthesia for War-Related Lower Limb Trauma
To compare the effectiveness of continuous regional anaesthesia with standard pain management strategies for the treatment of acute pain in patients with war-related lower limb trauma.
- Conditions
- Pain Management, Perioperative Analgesia, War-Related Injuries
- Trial name
- CRA-WAR-LIMB S (NCT07474506)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Residual Neuromuscular Blockade
Cardiac Output and Recovery Time
The purpose of this research is to determine the time it takes to reverse the effects of the intraoperative medication given to relax the muscles and how this period of recovery correlates with a function of the heart.
- Trial name
- NCT04619225
- Testing
- TetraGraph
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Mayo Clinic
Anesthesia, Recovery Period
TAPB vs. Caudal for Lower Abdominal Surgery in Children: A Double-Blinded Randomized Controlled Trial
Transversus abdominis plane block (TAPB) has emerged as a safe and effective regional anesthesia technique for providing postoperative lower abdominal analgesia.
- Trial name
- NCT02160821
- Testing
- Caudal Epidural, Transversus Abdominis Plane Block
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Nemours Children's Clinic
Laparoscopic Inguinal Hernia Repair, Quality of Recovery (QoR-15)
The Effects of Abdominal Plane Blocks on Postoperative Quality of Recovery
In laparoscopic inguinal hernia surgeries, although the effects of classical transversus abdominis plane (TAP) and Modified thoracoabdominal nerve block through perichondrial approach (m-TAPA) blocks on perioperative pain control…
- Conditions
- Laparoscopic Inguinal Hernia Repair, Quality of Recovery (QoR-15), Postoperative Analgesia, Regional Anesthesia
- Trial name
- NCT06753240
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Anesthesia, Obesity, Morbid
Effect of Two Different Doses of Dexmedetomidine Infusion in Morbidly Obese Patients
Compare the effects of two different doses of dexmedetomidine infusion on oxygenation as a primary outcome and on lung mechanics, quality of recovery and perioperative analgesia as secondary outcomes in morbidly obese patients…
- Conditions
- Anesthesia, Obesity, Morbid, Dexmedetomidine
- Trial name
- NCT06018948
- Testing
- Dexmedetomidine 0.6, Dexmedetomidine 0.3, Saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Anaesthesia
Study of Anaesthesia Costs and Recovery Profiles
The purpose of this study is to compare the perioperative hemodynamic parameters, recovery profiles and cost containment of sevoflurane and propofol based general anesthesia for otorhinolaryngeal surgery.
- Trial name
- SACRP (NCT02920749)
- Testing
- Sevoflurane group A, Sevoflurane group B, Propofol group C
- Where
- Hungary
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Anesthesia, Neuromuscular Blockade
Comparing Train-of-Four Recovery in the Adductor Pollicis Versus the Adductor Digiti Minimi in Elective Surgery Patients
The train-of-four (TOF) ratio is a quantitative measure used in anesthesia to assess the degree of neuromuscular blockade induced by neuromuscular blocking agents during surgical procedures.
- Trial name
- NCT06467448
- Testing
- EMG Assessement of Recovery of Neuromuscular Function
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of North Carolina, Chapel Hill
Is an Only Child
Use of Intraoperative Clonidine for Prevention of Postoperative Agitation in Pedriatic Anesthesia With Sevoflurane.
The purpose of this study is to determine efficacy of intraoperative clonidine to prevent postoperative agitation in pediatric anesthesia with sevoflurane.
- Trial name
- NCT02181543
- Testing
- Clonidine
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Postoperative Complications
Korean Version of the "Quality of Recovery 15" After General Anesthesia
The aim of this study is to test the Korean version of QoR-15 for its validity and clinical acceptability and feasibility.
- Trial name
- NCT04169087
- Testing
- QoR-15
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University Hospital
Hepatectomy, Pain, Postoperative
Spinal Anesthesia For Enhanced Recovery After Liver Surgery
This project proposes to compare epidural versus spinal anesthesia in patients having liver resection surgery. The investigators hypothesize that spinal anesthesia will result in improved blood pressure control postoperatively…
- Conditions
- Hepatectomy, Pain, Postoperative, Liver Neoplasms
- Trial name
- SAFER-L (NCT03715517)
- Testing
- Continuous thoracic epidural analgesia, Spinal anesthesia with intrathecal morphine, Bupivacaine 0.75% in Dextrose Inj 8.25%
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- University of Manitoba
Foot Deformities, Regional Anesthesia Morbidity
Impact of Virtual Reality Hypno-sedation on Functional Recovery and Anxiety in Foot Surgery With Regional Anesthesia
This prospective study aims to evaluate whether the implementation of a virtual reality hypnosedation (VRH)protocol reduces preoperative anxiety and increases patient comfort before, during, and after outpatient foot surgery.
- Conditions
- Foot Deformities, Regional Anesthesia Morbidity, Valgus; Hallux, Analgesia
- Trial name
- NCT05558449
- Testing
- Hypnosedation, Midazolam injection, Virtual reality
- Where
- Belgium
- Volunteers
- 57 people
- Sponsor
- University of Liege
Unruptured Cerebral Aneurysm
Impact of Genetic Polymorphism on Propofol Requirement and Recovery for Total Intravenous Anesthesia for Clipping of Unruptured Cerebral Aneurysm in Korean Population
In neurosurgical anesthesia, propofol based total intravenous anesthesia (TIVA) is frequently used due to brain relaxation and less effect on electrophysiologic monitoring.
- Trial name
- NCT02700126
- Where
- South Korea
- Volunteers
- 118 people
- Sponsor
- Yonsei University
Cervical Incompetence in Pregnancy as Antepartum Condition
Hyperbaric Prilocaine Compared With Hyperbaric Bupivacaine in Cervical Cerclage?
Patients that have a "cervical stitch" (cervical cerclage) require an anaesthetic. The most common choice is a spinal block. This is an injection in the back that makes the lower half of the body become temporarily numb and weak.
- Trial name
- PRILOCC (NCT04394533)
- Testing
- Prilocaine (Hyperbaric 2%), Bupivacaine (Hyperbaric 0.5%)
- Where
- United Kingdom
- Volunteers
- 129 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
ADHD - Attention Deficit Disorder With Hyperactivity
Clinical Study of Non-invasive 40-Hz Audiovisual Stimulation Guided by Gamma EEG Monitoring for Promoting Perioperative Brain Function Recovery in Children
Exposure to general anesthesia during early brain development has emerged as an important risk factor for long-term attention-deficit/hyperactivity disorder (ADHD)-like behaviors and learning difficulties in school-aged children.
- Trial name
- NCT07719465
- Testing
- 40-Hz non-invasive synchronized audiovisual stimulation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Cesarean Sections
Thoracic vs Lumbar Spinal Anesthesia for Cesarean Delivery
This randomized controlled trial aims to compare the effects of thoracic segmental spinal anesthesia and conventional lumbar spinal anesthesia on postoperative recovery in patients undergoing elective cesarean section.
- Trial name
- NCT07567612
- Testing
- Thoracic Segmental Spinal Anesthesia, Lumbar Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Adiyaman University Research Hospital
Laparoscopic Gynecological Surgery
EEG and ANI Guided Anesthesia and Quality of Recovery
This study aims to assess whether electroencephalogram (EEG) and nociception level-guided anesthesia can improve quality of recovery after laparoscopic gynecological surgery compared with standard care.
- Trial name
- NCT05936671
- Testing
- EEG-and-ANI-guided anesthesia, standard anesthesia, Sevoflurane and remifentanil
- Where
- 2 sites in South Korea
- Volunteers
- 126 people
- Sponsor
- Gangnam Severance Hospital
Pain, Postoperative, Rebound Pain
Intravenous Dexamethasone With Single-Shot Versus Continuous Brachial Plexus Block for Rebound Pain After Shoulder Surgery
Shoulder surgery often causes severe pain after the operation. To control this pain, doctors commonly perform a nerve block (interscalene brachial plexus block), which numbs the shoulder area.
- Conditions
- Pain, Postoperative, Rebound Pain, Shoulder Injuries, Rotator Cuff Injuries
- Trial name
- NCT07699744
- Testing
- Dexamethasone (IV), Single-shot interscalene brachial plexus block, Continuous interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Obese Adolescents, Bariatric Surgery
Study Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery if it Can Enhance Recovery From Anesthesia
study Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery if it Can Enhance Recovery From Anesthesia and provide improvement in recovery
- Trial name
- modafinil (NCT07128719)
- Testing
- Modafinil
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University