Clinical trials: Anesthesia, Spinal
Pain, Postoperative
US-guided Thoracic Spinal Epidural Anesthesia VS GA for Abdominal and Breast Surgeries
Ultrasound-guided combined thoracic segmental spinal epidural anesthesia in comparison with general anesthesia in upper abdominal and breast surgery.
- Trial name
- NCT05587608
- Testing
- combined thoracic segmental spinal epidural anesthesia
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- South Egypt Cancer Institute
Healthy
Hemodynamic Measurements During Cesarean Section With Spinal Anesthesia
The purpose of this study is to determine the effect of low dose versus standard dose spinal anesthesia with and without intravenous phenylephrine-infusion on blood pressure, cardiac output and systemic vascular resistance.
- Trial name
- NCT00199784
- Testing
- Phenylephrine
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Hypotension
Transcutaneous Electrical Acupoint Stimulation (TEAS) on Prevention Hypotension in Elderly
Despite prophylactic measures, hypotension remains a common side-effect of spinal anesthesia. Electroacupuncture influences hemodynamics.
- Trial name
- NCT05272033
- Testing
- Transcutaneous Electrical Acupoint Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Anesthesia, Spinal
'' Abdominal Crunch Positions With the Others in Terms of Interspinous Distance in Adult Patients ''
The most important factor for ease of operation and safety during spinal anesthesia is the determination of the spinal space. Increasing lumbar flexion facilitates access to the spinal space.
- Trial name
- NCT04092478
- Testing
- Spinal Anesthesia Position
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Konya Meram State Hospital
Cervical Incompetence
Comparison of Anesthesia Type in Patients Undergoing Transabdominal Cervico Isthmic Cerclage (TCIC)
The investigator aimed to compare the effect of anesthesia on overall postoperative outcomes including post-operative pain score and the fetal well-being (heart rate) in patients undergoing transabdominal cervico isthmic…
- Trial name
- NCT03636048
- Testing
- Bupivacaine Hcl 0.5% Inj, Propofol 10 milligram/ML
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Knee Arthroscopy
Estimation of Effective Dose 95 (ED95) of Intrathecal Isobaric 2-chloroprocaine (2-CP) Based on the Height (cm) of a Patient Undergoing Ambulatory Knee Arthroscopy
In ambulatory surgery, the choice of the local anesthetic used is essential. The ideal local anesthetic must allow a quick installation of the spinal block, a duration of the sensory block adapted to the surgery with a minimum of…
- Trial name
- NCT03882489
- Testing
- Isobaric 2-chloroprocaine
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Sleep Apnea Syndromes
Impact of Intrathecal Morphine on Sleep Apnea Syndrome
Intrathecal morphine is commonly used as an analgesic adjunct for hip arthroplasty performed under spinal anaesthesia. Sleep apnea syndrome is a condition that affects up to 10% of the patients.
- Trial name
- NCT02566226
- Testing
- Bupivacaine with normal saline, Bupivacaine with intrathecal morphine
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Hypotension Drug-Induced
Comparison of Different Protocols of Fluid Therapy in Severe Preeclamptic Patients Under Spinal Anesthesia
To compare the effect of two different protocol of fluid therapy in sever preeclamptic patients under spinal anesthesia : Hemodynamic and kidney function .
- Trial name
- NCT03478618
- Testing
- Lactated Ringer
- Volunteers
- 60 people
- Sponsor
- Assiut University
Anesthesia
The Efficacy of Pregabalin on the Duration of the Spinal Anesthesia and the Early Postoperative Pain After Total Knee Arthroplasty
the purpose of this study is to evaluate the effectiveness of administration of pregabalin 2 hours preoperatively on the onset and the duration of the spinal anesthesia in total knee arthroplasty and the role of pregabalin in…
- Trial name
- NCT05071118
- Testing
- Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Postoperative Pain
Postoperative Pain Control After Kidney Surgery : a Comparison of Intrathecal Morphine Plus PCA and PCA Only
postoperative pain after kidney surgery is very high. We always use PCA for postopertive pain. But almost patients still had severe pain. We try to use spinal morphine before operation aims to reduce pain.
- Trial name
- NCT00199316
- Testing
- spinal morphine
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Khon Kaen University
Anesthesia; Adverse Effect, Spinal and Epidural, Headache, Complications; Anesthesia, Spinal and Epidural, in Pregnancy
Comparison of Two Spinal Needles Regarding Postdural Puncture Headache
The aim of the study is to observe the rate of postdural puncture headache observed after spinal anesthesia in cesarean section patients. Two kind of spinal anesthesia needles will be used: 1.
- Trial name
- NCT01821807
- Where
- Turkey (Türkiye)
- Volunteers
- 256 people
- Sponsor
- Adiyaman University Research Hospital
Pain, Postoperative, Analgesia
Comparison of Postoperative Analgesic Efficacy of Caudal Block Versus Spinal Block With Levobupivacaine for Inguinal Hernia in Children
Neuraxial analgesia may improve postoperative outcomes for high-risk children who are susceptible to respiratory complications (e.g. post-operative apnea).
- Trial name
- NCT05117281
- Testing
- Levobupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Hypotension, Ischemia
Phase III Study of Hemospan® to Prevent Hypotension in Hip Arthroplasty
The purpose of this study is to determine whether Hemospan is superior to Voluven for preventing hypotensive episodes during the perioperative period (from induction of spinal anesthesia until 6 hours after skin closure), and for…
- Trial name
- NCT00421200
- Testing
- Hemospan (MP4OX), Voluven (HES 130/0.4)
- Where
- 18 sites in Belgium, Czechia and 4 more
- Volunteers
- 375 people
- Sponsor
- Sangart
Pain, Postoperative, Hysterectomy
Observational Retrospective Study on Spinal Analgesia in Laparoscopic and Laparotomic Hysterectomy
Perioperative multimodal analgesia, defined by the use of various analgesic medications targeting different drug receptors, provides adequate pain relief with minimal or no opiate consumption.
- Conditions
- Pain, Postoperative, Hysterectomy, Morphine, Anesthesia, Spinal
- Trial name
- SPIN_GYN (NCT05654363)
- Testing
- Administration of morphine by intrathecal route, Administration of morphine by intravenous route
- Where
- Italy
- Volunteers
- 670 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Labor Pain
Dexmedetomidine vs Fentanyl in Controlling Labor Pain
As most woman experience agonizing pain throughout vaginal labor. Adjuvants were added to intrathecal bupivacaine aiming to improve the quality of analgesia.
- Trial name
- NCT06392321
- Testing
- Fentanyl, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Al-Azhar University
Perfusion Index, Position Differences
Evaluation Of The Effects Of Changes In Operating Table Position On Perfusion Index And Spinal Anesthesia
The aim of this observational study is to investigate how table position affects the development of block in patients undergoing spinal anesthesia. Perfusion index measurements will be used to answer this question.
- Trial name
- Perfusion (NCT07400185)
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Enes Celik
Spinal Anesthetic Toxicity
The Effect of Different Degree of Temperature on Levobupivacaine Spinal Anesthesia
This study will be conducted to evaluate the effect of different temperature on the spinal anesthesia characteristics and incidence of complications
- Trial name
- NCT03790163
- Testing
- Levobupivacaine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University Hospital
Vaginal Hysterectomy, Suburethral Slings
Sedation With Dexmedetomidine Versus Remifentanil in Urogynecological Surgery Under Spinal Anaesthesia
Neuraxial blocks are usually used as an anaesthetic method for urogynecological surgeries. In most patients under regional anaesthesia, premedication is given for reducing anxiety.
- Trial name
- NCT03883347
- Testing
- Dexmedetomidine, Remifentanil
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- University of Athens
Post Spinal Anesthesia Shivering
Intrathecal DEX With Bupivacaine Inpost-spinal Shivering After CS.
This prospective, randomized, double-blind, placebo-controlled study to determine whether intrathecal dexmedetomidine, administered along with hyperbaric bupivacaine for covering Cesarean delivery decreases the incidence of…
- Trial name
- DEX (NCT06942000)
- Testing
- dexmedetomidine 3mcg group, dexmedetomidine 5mcg, preservative-free 0.9% saline.
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Spinal Anesthesia
Ultrasound-assisted Spinal Anaesthesia in Patients With Difficult Anatomical Landmarks
Spinal anesthesia is the technique of choice in patients undergoing total joint arthroplasty at Toronto Western Hospital (UHN). The most significant predictor of the ease of performance of spinal anesthesia is the quality of…
- Trial name
- NCT00956137
- Testing
- Ultrasound guidance, Manual palpation
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- University Health Network, Toronto