Clinical trials: Anesthesia,Spinal
Conscious Sedation
Closed-loop Sedation of Propofol for Patients Undergoing Spinal Anesthesia
The purpose of this study is to compare the administration of a standard anesthetic drug (propofol) using an automatic, expert-based system versus a manually controlled system by the anesthesiologist.
- Trial name
- NCT01020643
- Testing
- controlled administration of propofol
- Where
- Canada
- Volunteers
- 203 people
- Sponsor
- Thomas Hemmerling
Pregnant Women
Estimation of the ED95 of Intrathecal Hyperbaric Prilocaine 2% With Sufentanyl for Scheduled Cesarean Delivery
Hyperbaric bupivacaine 0.5% associated with opioids is the local anesthetic the most commonly used for spinal injection in cesarean section.
- Trial name
- NCT03036384
- Testing
- HB Prilocaine 2% (varying dose), HB Prilocaine 2%, Sufentanil
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Cerebral Oxygen Saturation During Spinal Anesthesia for Cesarean Delivery
Spinal Anesthesia for Cesarean Delivery is Associated With Decreases in Regional Cerebral Oxygen Saturation as Assessed by Near- Infrared Spectroscopy
The cerebral oxygen saturation is assessed by means of near-infrared spectometry in parturients undergoing cesarean delivery under spinal anesthesia.
- Trial name
- NCT01669135
- Testing
- Spinal Anesthesia with cerebral oxygen saturation monitoring
- Where
- Greece
- Volunteers
- 34 people
- Sponsor
- University of Athens
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery
Opioid overuse is a widespread public health crisis in the United States with increasing rates of addiction and overdose deaths from prescription opioids.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Spondylolisthesis, Lumbar Spondylosis
- Trial name
- NCT05029726
- Testing
- Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine, normal saline
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- John O'Toole
Fractures, Hip, Femoral Neck Fractures
Preoperative Use of Peripheral Nerve Blocks in Elderly Patients With Hip Fractures
The goal of this clinical trial is to explore the effects of different peripheral nerve blocks in older adults with hip fractures. It will also explore the safety of preoperative administration of peripheral nerve blocks.
- Conditions
- Fractures, Hip, Femoral Neck Fractures, Intertrochanteric Fractures, Subtrochanteric Fractures
- Trial name
- NCT07130006
- Testing
- PENG and LFCN peripheral nerve blocks with spinal anesthesia, FN and LFCN peripheral nerve blocks with spinal anesthesia, FIC peripheral nerve block with spinal anesthesia
- Where
- Croatia
- Volunteers
- 256 people
- Sponsor
- University Hospital of Split
Postoperative Pain, Acute
Ketorolac Intravenous Regional Analgesia in Lower Limb Surgeries
Tourniquet, a compressing device, otherwise its use in intravenous regional anesthesia, is commonly used in particular orthopedic surgeries.
- Trial name
- K-IVRAg (NCT05543785)
- Testing
- Ketorolac, Control
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Mansoura University
Anesthesia; Adverse Effect, Cesarean Section Complications
Comparison Between Three Norepinephrine Bolus Doses for Management of Post-spinal Hypotension During Ceaserian Section for Patients With Preeclampsia
Maternal hypotension after subarachnoid block is a frequent and deleterious complication during lower segment caesarean section (LSCS). Prophylaxis against hypotension using vasopressors had become a standard recommendation.
- Trial name
- NCT05368415
- Testing
- Norepinephrine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Cesarean Section
Ultrasound Guided Spinal Anesthesia in Non Obese Obstetric Patients
The classical method for spinal anesthesia relies on the use of bony landmarks to identify the level and point of entry of the spinal needle.
- Trial name
- NCT01440400
- Testing
- Ultrasound guided spinal anesthesia
- Where
- United Arab Emirates
- Volunteers
- 150 people
- Sponsor
- Corniche Hospital
Cesarean Section Complications, Spinal Anesthetic Toxicity
Comparison of Vasopressor Boluses for Management of Hypotension After Spinal Anesthesia
In this study the investigators will compare the efficacy and side effects of two doses of norepinephrine bolus (6 mcg and 10 mcg) in management of maternal hypotensive episode after subarachnoid block during Cesarean delivery.
- Trial name
- NCT03712111
- Testing
- Norepinephrine 6 mcg, Norepinephrine 10 mcg, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Cairo University
Perioperative Infusion, Ephedrine
Prophylactic Perioperative Infusion of Ephedrine Versus Noradrenaline in Patients Undergoing Cesarean Delivery Under Spinal Anesthesia
This study aimed to compare the effects of prophylactic ephedrine and nor-epinephrine infusion on maternal hemodynamics and neonatal outcomes following spinal anesthesia in cesarean deliveries.
- Conditions
- Perioperative Infusion, Ephedrine, Noradrenaline, Cesarean Delivery
- Trial name
- NCT07067944
- Testing
- Ephedrine, Noradrenaline
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Kidney Calculi
Effect of Anesthesia Type on Surgeon Workload During Endoscopic Kidney Stone Surgery
This prospective observational study aims to evaluate the association between anesthesia type and surgeon-perceived workload and surgical ergonomics in adult patients undergoing flexible ureteroscopy and retrograde intrarenal…
- Trial name
- RIRS-ERG (NCT07763600)
- Testing
- General Anesthesia (GA), Spinal Anesthesia (SA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Malatya Governor Research Hospital
Hypertrophic Pyloric Stenosis, Spinal Anesthesia
Spinal Anesthesia and General Anesthesia for Pyloromyotomy - Surgical Outcomes a Comparison Retrospective Study
Background: The purpose of this retrospective study is to evaluate surgical outcomes of pyloromyotomy in infants performed under spinal anesthesia compares to general anesthesia.
- Conditions
- Hypertrophic Pyloric Stenosis, Spinal Anesthesia, General Anesthesia
- Trial name
- NCT03095144
- Testing
- Spinal anesthesia, General anesthesia
- Volunteers
- 100 people
- Sponsor
- Bnai Zion Medical Center
Sleep Disorder, Sleep, Inadequate
Measuring Sleep Quality In Patients That Posterior Spinal Instrumentatıon Plannıng
Postoperative sleep disorders have serious problems with cognition, pain perception, sustained circadian rhythm, psychomotor function, metabolic function, catabolic responses, and continuity.
- Conditions
- Sleep Disorder, Sleep, Inadequate, Total ıntravenous Anesthesia, Inhalation Anesthesia
- Trial name
- NCT06269328
- Testing
- Total ıntravenous anesthesia with propofol and remifentanil for anesthetic maintenance, Inhalation anesthesia with sevoflurane for anesthetic maintenance
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Uludag University
Sensation Diminished, Pinprick
A Device to Determine Return of Sensation From Spinal Block
Participation in this study will involve having a pad wrapped onto the subject's non-surgical leg to detect when sensation returns after spinal anesthetic and while in recovery room.
- Trial name
- NCT04553913
- Testing
- cooling device
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Wake Forest University Health Sciences
Inguinal Hernia, Urinary Retention
Prophylactic Administration of Alpha Blockers for Prevention of Urinary Retention in Males Undergoing Inguinal Hernia Repair Under Spinal Anaesthesia.
Open inguinal hernia repair is one of the most common surgical procedures. Despite the fact that different of anesthetic procedures are proposed as alternatives to spinal anesthesia, the combination of spinal anesthesia with open…
- Trial name
- NCT03976934
- Testing
- Tamsulosin
- Where
- 2 sites in Greece
- Volunteers
- 100 people
- Sponsor
- Georgios Koukoulis
Chills
Comparison Of Dexmedetomidine & Ketamine For Control Of Shivering In Vaginal Hysterectomy Under Spinal Anesthesia
comparison of Dexmedetomidine And Ketamine For Control Of Shivering In Vaginal Hysterectomy Proceeded Under Spinal Anesthesia.
- Trial name
- NCT05481281
- Testing
- Dexmedetomidine, Ketamine
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Hamdard University
Anesthesia; Adverse Effect, Newborn Morbidity
Does the Mode of Anesthesia Affect the Feto-maternal Outcome in Category-1 Caesarean Section
Spinal anesthesia (SA) has become the standard technique in elective cesarean section (CS) as it results in less maternal and neonatal morbidity than general anesthesia (GA) (Grade-A recommendation, NICE).
- Trial name
- NCT04634981
- Testing
- anesthesia of emergency cesarean section
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Benha University
Pain, Postoperative, Opioid Use
Spinal Anesthesia and Peri-operative Opioid Consumption in Open Abdominal Prostatectomy
Retrospective analysis to assess the impact of spinal anesthesia on peri-operative opioid consumption during open abdominal prostatectomy.
- Conditions
- Pain, Postoperative, Opioid Use, Analgesia
- Trial name
- SAPOC (NCT03565705)
- Testing
- Open abdominal prostatectomy
- Where
- Germany
- Volunteers
- 636 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Hearing Loss; Post-Dural Puncture Headache; Cesarean Delivery
Evaluation of Postoperative Hearing Loss After Spinal Anesthesia for Elective Cesarean Section in Pregnant Women
This prospective observational study will evaluate postoperative hearing changes in women undergoing elective cesarean delivery under spinal anesthesia.
- Trial name
- NCT07697651
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Duzce University
Cervical Incompetence
Intrathecal Chloroprocaine vs. Bupivacaine for Cervical Cerclage
This study aims to compare the effect of chloroprocaine vs. bupivacaine on duration of motor block and duration until meeting discharge criteria in patients undergoing cervical cerclage.
- Trial name
- NCT03305575
- Testing
- Chloroprocaine, Bupivacaine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Tufts Medical Center