Clinical trials: Anesthesia,Spinal
Analgesia
Efficacy of Coadministration of Calcitonin and Hyperbaric Bupivacaine in Spinal Anesthesia in Tramadol-abuse Patients
Increasing duration of local anesthetic action is desired for prolongation of postoperative patient comfort, as well as decreasing perioperative opioid consumption and subsequent side effects.
- Trial name
- NCT04445857
- Testing
- Calcitonin presented as Miacalcic® ampoules 100 IU/ml (1ml) intrathecally, Calcitonin presented as Miacalcic® ampoules 100 IU/ml (1ml) intravenously, Normal Saline (NS)
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Cancer Surgery
Landmark Versus Ultrasongraphy Guided Spinal Anesthesia in Lower Abdominal Surgeries in Cancer Patients: a Randomized Controlled Trial
Spinal anesthesia is a commonly employed technique for lower abdominal surgeries, providing effective anesthesia and analgesia with minimal systemic effects.
- Trial name
- NCT06707571
- Testing
- spinal anesthesia
- Volunteers
- 52 people
- Sponsor
- Assiut University
Prostate Cancer Surgery
Spinal Anesthesia for Robotic Assisted Laparoscopic Prostatectomy
The investigators hypothesised that spinal anesthesia as an adjunct to general anesthesia would facilitate faster recovery and less pain in patients undergoing laparoscopic robotic prostatectomy.
- Trial name
- NCT06860893
- Testing
- Spinal Anesthesia with Bupivacaine
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- University Hospital of North Norway
Pain, Postoperative, Pain
Improved Rehabilitation After Spinal Surgery in Adolescents
Impact of the OFA technique on postoperative recovery from adolescent spine surgery and the incidence of chronic postoperative pain.
- Conditions
- Pain, Postoperative, Pain, Scoliosis, Spinal Fusion
- Trial name
- NCT04183049
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Nantes University Hospital
Lower Limb Orthopedic Surgery
Intravenous Dexmedetomidine Versus Midazolam in Preventing Shivering in Trauma Patients Undergoing Lower Limb Orthopedic Surgery Under Spinal Anesthesia
Shivering is a common and significant complication following spinal anesthesia, with a reported incidence of 40-60% especially in trauma patients due to pain, stress response, blood loss, and disrupted thermoregulation.
- Trial name
- NCT07300826
- Testing
- Dexmedetomidine, Midazolam
- Volunteers
- 100 people
- Sponsor
- Assiut University
Anesthesia Local
Comparison of Combined Sciatic(Winnie's) Femoral Nerve Block, and Subarachnoid Block Anesthesia for Lower Limb Surgery
60 ASA grades- I, II or III patients, undergoing lower limb surgeries, will be randomly allocated in 2 groups of 30 patients each.
- Trial name
- NCT02713685
- Testing
- Subarachnoid block, combined Femoral and Sciatic nerve block
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Government Medical College, Haldwani
Pain, Postoperative, Lumbar Spine Degeneration
Epidural PCA on Pain Relief After L-spine Surgery
This study aimed to evaluate the effect of epidural patient-controlled analgesia (PCA) on postoperative pain relief after lumbar spine surgeries.
- Conditions
- Pain, Postoperative, Lumbar Spine Degeneration, Analgesia, Patient-Controlled, Epidural Anesthesia
- Trial name
- NCT06316921
- Testing
- Epidural patient-controlled analgesia, Standard postoperative pain management
- Where
- Taiwan
- Volunteers
- 209 people
- Sponsor
- Taipei City Hospital
Healthy
Hemodynamic Measurements During Cesarean Section With Spinal Anesthesia
The purpose of this study is to determine the effect of low dose versus standard dose spinal anesthesia with and without intravenous phenylephrine-infusion on blood pressure, cardiac output and systemic vascular resistance.
- Trial name
- NCT00199784
- Testing
- Phenylephrine
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Ultrasound
Ultrasound Versus Palpation for Spinal Anesthesia Success
Aim is to investigate the difference in number of attempts to place neuraxial block comparing handheld ultrasound versus use of palpation alone for women with impalpable bony landmarks undergoing spinal anesthesia for elective…
- Trial name
- Accuro (NCT03679663)
- Testing
- Ultrasound
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cesarean Section Complications, Spinal Anesthesia
Norepinephrine Versus Phenylephrine Continuous Variable Infusion in Cesarean Delivery
Comparison will be conducted between continuous variable infusions of Phenylephrine with starting dose of 0.75 mcg/Kg/min and Norepinephrine Bitartrate with starting dose of 0.1 mcg/Kg/min (with norepinephrine base of 0.05…
- Trial name
- NCT03328533
- Testing
- Phenylephrine, Norepinephrine, Bupivacaine
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Cairo University
Hip Fractures
Combined Plexus Block for Hip Fracture Surgery.
Hip fracture surgery requires high risk anesthetic procedure for elderly patients (1). General anesthesia, continuous spinal anesthesia and peripheral nerve blocks are three anesthetic techniques possible.
- Trial name
- NCT03356704
- Testing
- no intervention
- Volunteers
- 593 people
- Sponsor
- University Hospital, Montpellier
Spinal Aneshtesia, General Anesthetic
Effects of Anesthesia Type on Inflammatory Response
In total knee arthroplasty, surgical and anesthetic procedures can lead to a significant increase in systemic inflammation. This procedure is frequently performed under either general or spinal anesthesia.
- Conditions
- Spinal Aneshtesia, General Anesthetic, Inflammation, Neutrophils
- Trial name
- NCT06984315
- Testing
- The effects of the groups on perioperative inflammation changes were compared.
- Where
- Turkey (Türkiye)
- Volunteers
- 849 people
- Sponsor
- Tokat Gaziosmanpasa University
Pregnancy Induced Hypertension
Fractionated Vs Single Dose Injection for Spinal C-Section in Patients With Pregnancy-Induced Hypertension
The aim of this study was to compare haemodynamic changes, total dose of ephedrin requirement, and level of sensory blockade between fractionated dose and single dose spinal anesthesia injection in obstetric patients with…
- Trial name
- NCT03693638
- Testing
- Bupivacaine-fentanyl
- Where
- Indonesia
- Volunteers
- 42 people
- Sponsor
- Universitas Indonesia
Maternal Hypotension Associated With Spinal Anesthesia During Cesarean Section
The Effect of Compression Stockings and Leg Elevation on Hemodynamic Stability in Elective Cesarean Sections Under Spinal Anesthesia: A Single-Blind Randomized Controlled Trial
Aim: This study aimed to evaluate the effects of compression stockings and leg elevation on maternal intraoperative hypotension, vasopressor requirement, and neonatal well-being parameters in women undergoing elective cesarean…
- Trial name
- NCT07534891
- Testing
- compression stockings, Leg elevation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Seçil Yavaş
Inguinal Hernia Repair, Postoperative Pain
Spinal Anesthesia Versus Erector Spina Plane Block
The primary aim of our study was to use spinal anesthesia for unilateral inguinal hernia surgery and lumbar erector spina block supported by local infiltration anesthesia in terms of operation time, intraoperative hemodynamic…
- Conditions
- Inguinal Hernia Repair, Postoperative Pain, Peripheral Nerve Blocks
- Trial name
- NCT05073055
- Testing
- İnguinal Hernia Repair
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Nigde Omer Halisdemir University
Cesarean Section, Hypotension
Effect of Oxytocin Bolus Versus Slow Infusion on Haemodynamic Stability During Caesarean Section Under Spinal Anaesthesia
This study compares two standard ways of giving oxytocin (a medicine that helps the uterus contract) after the baby is born during a planned caesarean section performed under spinal anaesthesia.
- Conditions
- Cesarean Section, Hypotension, Postpartum Hemorrhage, Spinal Anesthesia
- Trial name
- NCT07784478
- Testing
- Oxytocin
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Khyber Girls Medical College
HoLEP, QoR-40
Effect of Anesthesia Techniques on Quality of Recovery Scores in HOLEP Surgery
The aim of this observational study is to evaluate the effects of different anesthesia techniques on the quality of recovery (QoR) and patient satisfaction in male patients, typically older adults with benign prostatic…
- Conditions
- HoLEP, QoR-40, Anesthesia, General, Anesthesia,Spinal
- Trial name
- NCT07020390
- Testing
- Anesthesia method
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people
- Sponsor
- TC Erciyes University
Combined Spinal-epidural Anesthesia
Relationship Between ANI, Anxiety, and Pain in Conscious Hernia Patients Undergoing CSEA
Analgesia Nociception Index can be used to detect noxious stimulation during general anesthesia.The aim of this study is to observe ANI under combined spinal epidural anesthesia procedures in conscious hernia patients.
- Trial name
- NCT05053633
- Testing
- Combined spinal epidural anesthesia
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Beijing Chao Yang Hospital
Post Spinal Anaesthesia Hypotension, Inferior Vena Cava Collapsibility Index
Inferior Vena Cava Collapsibility Index Assessment in Predicting Post Spinal Anaesthesia Hypotension in Patients Undergoing Arthroscopic Knee Surgeries.
The aim of this study was to evaluate the role of inferior vena cava collapsibility index assessment in predicting post spinal anaesthesia hypotension in patients undergoing arthroscopic knee surgeries.
- Trial name
- NCT06767033
- Testing
- Ultrasound Guided Inferior Vena Cava Collapsibility Index Assessment
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Bradycardia, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Hyoscine Butylbromide for Prevention of Bradycardia During Cesarean Section
The aim of this study is to assess the efficacy of Iv hyoscine butylbromide in preventing Bradycardia during cesarean section under spinal anaesthesia with local anaesthetic and morphine.
- Conditions
- Bradycardia, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use, Cesarean Section Complications
- Trial name
- NCT04069078
- Testing
- Hyoscine Butylbromide 20 Mg/mL Solution for Injection Ampoule, Normal saline
- Where
- Egypt
- Volunteers
- 173 people
- Sponsor
- Assiut University