Clinical trials: Anesthesia,Spinal
Pregnancy, Labor Pain
Does Ultrasound of the Spine Improve Labor Epidurals/Spinal Anesthesia in Obstetric Patients?
The investigators are interested in determining the utility of ultrasound of the spine for labor epidurals or spinal anesthesia for women in labor or having a cesarean delivery.
- Trial name
- NCT01243216
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Post Operative Cognitive Dysfunction
Effect of Preoperative Hospitalization Duration on Post-operative Cognitive Dysfunction
Post-operative cognitive dysfunction is defined as a decrease in cognitive functions which develop following surgery and anesthesia administration that can last up to weeks or even months after surgery.
- Trial name
- NCT03290599
- Testing
- Mini Mental and Modified Mini Mental Test
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Burcu Ozalp Horsanali
Post-Operative Confusion
High Spinal Anesthesia and the Incidence of Delirium After Cardiac Surgery
This is a feasibility study to determine if enough patients undergoing elective or urgent cardiac surgery, can be enrolled in a study where patients are randomized to receive high spinal anesthesia as an adjunct to general…
- Trial name
- NCT05374356
- Testing
- Intrathecal bupivacaine and morphine
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Sedation; Aged; Hemodynamics
A Comparision of Midazolam-dexmedetomidine With Dexmedetomidine Alone for Hemodynamic Stability and Quality of Sedation in Elderly Patients Under Spinal Anesthesia
The purpose of this study is to compare midazolam-dexmedetomidine with dexmedetomidine alone for hemodynamic stability and quality of sedation in elderly patients under spinal anesthesia.
- Trial name
- NCT01979653
- Testing
- dexmedetomidine alone or dexmedetomidine + midazolam
- Where
- South Korea
- Sponsor
- Severance Hospital
Obstetric Pain
Quality of Postoperative Analgesia and Functional Recovery After Elective Cesarean Delivery
Based on randomization, patients will receive a mixture for spinal anesthesia and will be followed in the following hours for the various outcomes and for functional recovery
- Trial name
- MoFe (NCT06355271)
- Testing
- Fentanyl 1, Fentanyl2, Fentanyl 3
- Where
- Switzerland
- Volunteers
- 63 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Cesarean Section, Spinal Anesthesia
Predictability of ANI (Analgesia Nociception Index) for Spinal Hypotension
Spinal anesthesia is widely accepted as the anesthetic method of choice for Cesarean section. However, the incidence of spinal hypotension is 50-70%, and the decrease in blood pressure is often rapid and severe.
- Trial name
- NCT06327165
- Testing
- observation
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yonsei University
TURP(Transurethral Resection of Prostate), Spinal Anesthesia
Modified Saddle Block vs Spinal Anesthesia for TURP
After obtaining informed consent, eligible patients will be enrolled in the study. Standard monitoring will be applied in the operating room and baseline blood pressure and heart rate will be recorded.
- Conditions
- TURP(Transurethral Resection of Prostate), Spinal Anesthesia, Saddle Block Anesthesia, Hypotension During Surgery
- Trial name
- NCT07841184
- Testing
- Saddle block, Spinal Anesthesia (bupivacaine)
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Hemorrhoids
Ligasure Versus Diathermy Haemorrhoidectomy Under Local Anesthesia
The objective of this prospective randomised trial was to compare the short- and long-term efficacy of conventional diathermy haemorrhoidectomy versus Ligasure™ diathermy, and to assess the short-term outcome of each procedure…
- Trial name
- LDHLA (NCT00617448)
- Testing
- diathermy haemorrhoidectomy under espinal anesthesia, diathermy haemorrhoidectomy under local anesthesia, Ligasure haemorrhoidetomy under spinal anestesia
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Hospital de Viladecans
Arthritis, Degenerative
Intraoperative Sedatives and Postoperative Pain
In this study, based on the hypothesis that dexmedetomidine administered intraoperatively for sedation can reduce postoperative pain than that of propofol, the investigators examined the ability of dexmedetomidine to reduce…
- Trial name
- NCT02784626
- Testing
- Dexmedetomidine, Propofol
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Seoul National University Bundang Hospital
Postoperative Pain
Comparative Study of the Analgesic Effect of Spinal Anesthesia or Infiltration Anesthesia for Hemorrhoidectomy
Background and Objectives: Postoperative analgesia and early recovery are relevant for hospital discharge after hemorrhoidectomy.
- Trial name
- NCT02839538
- Testing
- Local Infiltration, Subarachnoidal block
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
PDPH
Prophylactic Intrathecal Normal Saline for Prevention of Post Dural Puncture Headache in Women Undergoing Cesarean Section Under Spinal Anesthesia
The rates of cesarean section are increasing worldwide despite ten to fifteen percent of World Health Organization recommendation and from which 80-90% of cesarean sections are performed with spinal anesthesia.
- Trial name
- PDPH (NCT04393766)
- Testing
- Normal Saline
- Where
- Ethiopia
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Dilla University
Hemodynamic Instability and Shivering
Comparative Study Between Intravenous Granisetron and Ondansetron on Their Effect on Hemodynamics and Shivering After Spinal Anesthesia in Elective Cesarean Delivery
Spinal anesthesia is commonly used in cesarean section surgeries . The most important adverse effects of spinal anesthesia are hypotension and bradycardia caused by sympathetic blockade, with an incidence of about 55-100% .
- Trial name
- NCT06437236
- Testing
- ondansetron, granisetron
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Hypotension, Spinal Anesthesia
Norepinephrine or Phenylephrine in Bolus for Hypotension in Cesarean Delivery
This study evaluate the ability of phenylephrine and of noradrenaline to maintain normal systemic arterial blood pressure and heart rate in healthy pregnant women submitted to cesarean section with spinal anesthesia.
- Trial name
- NCT03702400
- Testing
- Phenylephrine 100 mcg, Norepinephrine 5 mcg
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospital dos Servidores do Estado do Rio de Janeiro
Post Spinal Anaesthesia Hypotension, Transurethral Resection of the Prostate (TURP)
Ultrasound Assessment of Femoral Vein and Inferior Vena Cava Collapsibility to Predict Spinal Anesthesia-Induced Hypotension
Spinal anesthesia is commonly used in transurethral prostate resection (TUR-P) surgeries; however, post-spinal hypotension remains a frequent and clinically significant complication, particularly in elderly patients.
- Trial name
- NCT07497295
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Antalya Training and Research Hospital
Hypotension
Diastolic Performance and Norepinephrine in Spinal-Induced Hypotension for Cesarean Delivery
Background and rationale: The best agent to prevent spinal-induced hypotension is still uncertain but norepinephrine showed fewer effects on heart rate and cardiac output.
- Trial name
- NORA-CS (NCT04560634)
- Testing
- Norepinephrine, ClearSight®, Edwards Lifescience, Irvine, CA
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Post Spinal Anaesthesia Hypotension
Peripheral Perfusion Index as a Predictor of Post-spinal Hypotension in Patients Undergoing Lower Limb Surgeries
This prospective observational study was carried out on a sample of 40 patients over a period of 6 months to asses the peripheral perfusion index as a Predictor for post spinal hypotension in patient undergoing lower limp…
- Trial name
- NCT07279805
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Bladder Cancer
Influence of Anesthesia Methods on CTCs in TURBT Patients
Multiple lines of evidence have shown that anesthesia method is associated with long-term outcomes in patients undergoing surgery due to cancers, including lung, breast, prostate, and bladder cancer, etc.
- Trial name
- NCT05824299
- Testing
- General Anesthesia, Spinal Anesthesia
- Where
- China
- Volunteers
- 162 people
- Sponsor
- RenJi Hospital
Hip Fractures
Hypobaric Lateral Spinal Anesthesia Versus General Anesthesia for the Hip Fracture Surgery
Hip fracture is a frequent pathology, involving elderly patients with many co-morbidities ; therefore, post-operative morbidity and mortality is high.
- Trial name
- RACHYP (NCT03373864)
- Testing
- Unilateral spinal anesthesia, General anesthesia
- Where
- France
- Volunteers
- 154 people
- Sponsor
- Hospices Civils de Lyon
Pain, Postoperative, Hysterectomy
Observational Retrospective Study on Spinal Analgesia in Laparoscopic and Laparotomic Hysterectomy
Perioperative multimodal analgesia, defined by the use of various analgesic medications targeting different drug receptors, provides adequate pain relief with minimal or no opiate consumption.
- Conditions
- Pain, Postoperative, Hysterectomy, Morphine, Anesthesia, Spinal
- Trial name
- SPIN_GYN (NCT05654363)
- Testing
- Administration of morphine by intrathecal route, Administration of morphine by intravenous route
- Where
- Italy
- Volunteers
- 670 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Post Spinal Anaesthesia Hypotension, Geriatric Population
Effect of Dexamethasone on Post-spinal Hypotension
The goal of this clinical trial is to learn if intravenous dexamethasone is effective for prevention of post spinal hypotension in geriatric population undergoing orthopedic surgeries.
- Conditions
- Post Spinal Anaesthesia Hypotension, Geriatric Population, Orthopedic Surgeries
- Trial name
- NCT06819436
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma