Clinical trials: Anesthesia; Adverse Effect
Anesthesia; Adverse Effect
Neurotoxicity of Anesthesia in Middle Aged Patients
for the last 20 years, the increasing reports from non-human studies have raised suspicion that general anesthetics may cause neurotoxic changes in the developing brain that lead to adverse neurodevelopmental outcomes later in…
- Trial name
- NCT04275531
- Testing
- Anesthesia Agent
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Tanta University
Anesthesia Morbidity, Anesthesia; Adverse Effect
Comparison of CLSB With Sedation Versus General Endotracheal Anesthesia on Postoperative Outcomes in Elderly Patients Undergoing Hip Fracture Surgery
Hip fracture is a global public health problem. The postoperative mortality and disability rate of hip fracture is high, and early surgery is still the most effective treatment method, but these patients are often associated with…
- Trial name
- NCT03318133
- Testing
- anesthesia
- Where
- China
- Volunteers
- 1,086 people
- Sponsor
- Shanghai 6th People's Hospital
Anesthesia, Adverse Effect of Handovers of Anesthesia Care
Impact of Handover of Anesthesia Care on Adverse Postoperative Outcomes
Our goal is to conduct a prospective, national, randomized-controlled, multicenter trial to investigate the effect of handover of anesthesia care on the occurrence of adverse outcomes in the perioperative period.
- Trial name
- HandiCAP (NCT04016454)
- Testing
- Intervention
- Where
- 11 sites in Germany
- Volunteers
- 1,817 people
- Sponsor
- University Hospital Muenster
Anesthesia; Adverse Effect, Spinal and Epidural
Paramedian Incidence Angles in Spinal Anaesthesia
The objective here is to quantify the number of punctures and redirections during routine practice in the anesthesiology department, verify the final angle of incidence and the sac-skin distance by ultrasound, and determine the…
- Trial name
- NCT07210892
- Testing
- Measurement of needle insertion angles
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de Terrassa
Sedative Adverse Reaction
The Effect of Real-time Binaural Sound on Sedation Using Dexmedetomidine
The aim of the study is to evaluate whether real-time binaural sound affects the dose of dexmedetomidine in patients undergoing sedation with dexmedetomidine after spinal anesthesia.
- Trial name
- NCT04866433
- Testing
- Real-time binaural sound, Music, Control
- Where
- South Korea
- Volunteers
- 189 people
- Sponsor
- Seoul National University Hospital
Adverse Effect
ED90 of Norepinephrine and Phenylephrine Boluses Under Intensive Treatment in Preeclamptic Patients
The objective of this study is to investigate the ED90 of norepinephrine and phenylephrine boluses for treating postspinal anesthesia hypotension under intensive treatment in preeclamptic patients during cesarean section
- Trial name
- NCT06158035
- Testing
- Norepinephrine, Phenylephrine
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Intrathecal Dexmedetomidine
This Study Aims to Determine Whether Lower Doses (4 µg) of Intrathecal Dexmedetomidine Can Provide Comparable Analgesic Benefits While Minimizing Adverse Hemodynamic Effects in Patients Encountered in Our Setup( Shifa International Hospital Islamabad).
This study aims to determine whether lower doses (4 µg) of intrathecal dexmedetomidine can provide comparable analgesic benefits while minimizing adverse hemodynamic effects in patients encountered in our setup( Shifa…
- Trial name
- NCT07807020
- Testing
- Intrathecal Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shifa International Hospital
Anesthesia; Adverse Effect, Biliary Tract Diseases
Ciprofol vs Propofol for Reducing Hypoxia Incidence in ERCP
Intravenous anesthesia has been widely used in endoscopic retrograde cholangiopancreatography (ERCP). In the past decade, many practices have been carried out under the propofol-based monitored anesthesia care without…
- Trial name
- NCT06015074
- Testing
- Propofol, Ciprofol
- Where
- China
- Volunteers
- 136 people
- Sponsor
- RenJi Hospital
Remifentanil, Adverse Effects
Effect of Remifentanil on Pruritus and Paresthesia of Fospropofol Disodium Anesthesia
Explore the effect of remifentanil on pruritus and paresthesia induced by fospropofol disodium in adults
- Trial name
- NCT07092384
- Testing
- Remifentanil, Sufentanil
- Where
- China
- Volunteers
- 265 people
- Sponsor
- Tongji Hospital
Anesthesia, Anesthesia Morbidity
Anesthesia With Endotracheal Laser Tube
The study examines the special endotracheal laser tube during anesthesia of endolaryngeal laser surgery.
- Trial name
- NCT03044418
- Testing
- Application of ET laser tube in propofol anesthesia
- Where
- Hungary
- Volunteers
- 30 people
- Sponsor
- University of Pecs
Delirium in Old Age, Anesthesia; Adverse Effect
Postoperative Dexmedetomidine in Prevention of Postoperative Delirium
The goal of this clinical trial is to learn how postoperative infusion of dexmedetomidine would influence postoperative delirium in elderly patients undergoing lung surgery. The main questions it aims to answer are : 1.
- Trial name
- NCT06382961
- Testing
- Dexmedetomidine injection, Sufentanil injection
- Where
- China
- Volunteers
- 287 people
- Sponsor
- Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
Acute Kidney Injury, Hypotension
A Pilot Analysis of the Association Between Anesthesia Induction Dosing and AKI in the Elderly Population
This study proposes to perform a pilot observational study looking at the doses of propofol used for the induction of general anesthesia and its association with the development of hypotension and AKI among elderly patients at…
- Conditions
- Acute Kidney Injury, Hypotension, Anesthesia; Adverse Effect
- Trial name
- NCT03699696
- Testing
- Propofol
- Where
- United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Yale University
Postoperative Pain, Cesarean Section
Intrathecal Morphine 75 mcg Versus 100 mcg for Post-Cesarean Analgesia: A Randomized Double-blind Trial
This study evaluates the efficacy and safety of two different doses of intrathecal morphine (75 mcg versus 100 mcg) for postoperative analgesia in patients undergoing elective cesarean delivery under spinal anesthesia.
- Conditions
- Postoperative Pain, Cesarean Section, Obstetric Anesthesia
- Trial name
- ITM-CESAREAN (NCT07516717)
- Testing
- Intrathecal Morphine
- Where
- Venezuela
- Volunteers
- 240 people
- Sponsor
- Hospital Universitario de Caracas
Hernia, Anesthetics Adverse Reaction
Local or Regional or General Anesthesia for Hernia Repair: a Randomized Controlled Trial
This present randomized trial is designed to evaluate the postoperative pain,inflammatory marker, postoperative analgesic medication, length of hospital stay and the modifications of inflammatory mediators in patients undergoing…
- Conditions
- Hernia, Anesthetics Adverse Reaction, Inflammation
- Trial name
- NCT01845376
- Testing
- local anesthesia group, spinal anesthesia group, general anesthesia group
- Where
- Thailand
- Volunteers
- 54 people
- Sponsor
- Mingkwan Wongyingsinn, MD
Cataract Surgery, Patient Satisfaction
Evaluation of Duration of Anesthesia and Patient Satisfaction After Retrobulbar Block Applied in Cataract Surgery
It is aimed to determine patient satisfaction (pain assessment during and after the operation) and the initial and total anesthesia durations of eye lid and globe anesthesia after administration of local anesthetic solution only…
- Conditions
- Cataract Surgery, Patient Satisfaction, Akinesia, Anesthesia, Local
- Trial name
- NCT04178200
- Testing
- Lidocaine 2% Injectable Solution 0.75 ml, Bupivacaine Hcl 0.5% Inj 0.75 ml, Lidocaine 2% Injectable Solution 1.5 ml
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Develi Devlet Hastanesi
Perioperative Complication, Perioperative/Postoperative Complications
Registry of Anesthesia and Perioperative Medicine
To assess mortality and morbidity associated to anesthesia interventions
- Conditions
- Perioperative Complication, Perioperative/Postoperative Complications, Anesthesia Morbidity, Anesthesia; Adverse Effect
- Trial name
- RAMP (NCT05869578)
- Testing
- Anesthesia Intervention
- Where
- Chile
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Clinica Alemana de Santiago
Injection Site Irritation, Injection Site Bruising
Comparison of Subcutaneous Injection of Normal Saline and Bacteriostatic Saline
This is a randomized, double-blind, single-center clinical trial comparing normal saline and bacteriostatic saline subcutaneous injection within a single subject.
- Conditions
- Injection Site Irritation, Injection Site Bruising, Injection Site Discomfort, Benzoic Acid Adverse Reaction
- Trial name
- NCT05109000
- Testing
- Sodium Chloride 0.9% Inj, Bacteriostatic Sodium Chloride 0.9 % INJECTION VIAL (ML)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Jeffrey Alan Klein, MD
Adverse Anesthesia Outcome
The Effect of Preventive Use of Ondansetron in the Cesarean Section Under Spinal Anesthesia
Cesarean section is a frequent procedure in the obstetric surgery. The most widely used anesthesia technique for cesarean delivery is the spinal anesthesia The incidence of spinal anesthesia induced hypotension and bradycardia is…
- Trial name
- NCT02883192
- Testing
- Ondansetron
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Bnai Zion Medical Center
Anesthesia; Adverse Effect, Congenital Heart Disease
The Effect of Anesthesia on Neurodevelopmental Outcome (NDO)
The purpose of this study is to assess whether the type of anesthesia, narcotic-based versus inhalational anesthesia administered during cardiopulmonary bypass (CPB) surgery contributes to the wide variation in neurologic…
- Conditions
- Anesthesia; Adverse Effect, Congenital Heart Disease, Neurodevelopmental Disorders
- Trial name
- NDO (NCT03882788)
- Testing
- Isoflurane, Fentanyl (high dose), Fentanyl (low dose)
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Stanford University
Sore-throat, Dysphonia
No Post Intubation Laryngeal Symptoms
The purpose of the study is to test a novel endotracheal tube support device that reduces pressure of the tube on the voice box for prevention of post intubation laryngeal symptoms including sore throat, change in voice and…
- Conditions
- Sore-throat, Dysphonia, Dysphagia, Intubation Complication
- Trial name
- No-PILS (NCT05383417)
- Testing
- EndoClip
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego