Clinical trials: Anesthesia , Analgesia
First Trimester Abortion, Surgical Abortion
Impact of Music Intervention on Pain Control In First Trimester Surgical Abortion Under Local Anesthesia
A surgical abortion under local anesthesia is potentially painful. A protocol using analgetic is systematically used. Also the protocol is relevant , the question of taking care of the pain in a safe manner remains.
- Conditions
- First Trimester Abortion, Surgical Abortion, Music Intervention, Local Anesthesia
- Trial name
- AlgoMusic (NCT02922504)
- Testing
- Music intervention group, Controlled group
- Volunteers
- 159 people
- Sponsor
- University Hospital, Angers
Clubfoot
Clubfoot Tenotomy Trial
Infants undergoing Ponseti treatment for idiopathic clubfoot often require percutaneous tendoachilles lengthening (TAL) after serial casting.
- Trial name
- ClubTT (NCT04766684)
- Testing
- Jet injection of 1% lidocaine, 4% liposomal lidocaine cream
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Vanderbilt University Medical Center
Postoperative Pain
Clonidine and Morphine in Caudal Anesthesia
Hypothesis: The combined use of Clonidine and Morphine in caudal anesthesia provides better postoperative analgesia than either drug alone after urogenital pediatric surgery.
- Trial name
- NCT00672347
- Testing
- Clonidine, Morphine, Bupivacaine plus clonidine and morphine
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Federal University of Minas Gerais
Pregnancy
Aseptic Techniques During Epidural Analgesia in the Labor Floor
There is an increasing trend in the incidence of infection related to epidural anesthesia. This could be related to methods of aseptic technique as adopted by the anesthesiologist during the performance of the procedure.
- Trial name
- EAS (NCT01235858)
- Testing
- wearing of sterile gowns, No gown
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Nociceptive Pain, Anesthesia
Effect of Dexmedetomidine on Nol-Index Guided Remifentanil Analgesia
Background: Analgesia remains to this day a challenge for anesthesiologists. Dexmedetomidine, a potent central alpha-2 agonist, has been shown to have analgesic and opioid sparing effects.
- Conditions
- Nociceptive Pain, Anesthesia, Opioid Use, Perioperative/Postoperative Complications
- Trial name
- NCT03912740
- Testing
- Dexmedetomidine, sodium chloride, Remifentanil
- Where
- Belgium
- Volunteers
- 58 people
- Sponsor
- Erasme University Hospital
Toxicology, Bariatric Surgery Analgesia
Preoperative Toxicological Screening on Perioperative Anesthetic Management
Background: Preoperative substance use is a growing concern in patients undergoing metabolic bariatric surgery (MBS), but its impact on short-term outcomes remains debated.
- Conditions
- Toxicology, Bariatric Surgery Analgesia, Bariatric Surgery, Substance Use
- Trial name
- NCT07100314
- Testing
- Multi-Drug One Step Screen Test Panel (Urine)
- Where
- Egypt
- Volunteers
- 1,260 people
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Post-operative Pain, Anesthesia, Local
Evaluation of the Analgesic Benefit of Adding the Blocks of the Intermediate and Medial Femoral Cutaneous Nerves in Addition to the Femoral Triangle Block for Postoperative Analgesia After a Knee Replacement Surgery
Total knee replacement surgery can be associated with a significant postoperative pain burden and an inability to mobilize adequately, which can lead to the failure of the ambulatory course.
- Trial name
- NCT06038851
- Testing
- Para-Sartorial Compartments (PACS) Block, Femoral Triangle Block (FTB), Infiltration between popliteal artery and capsule of the knee (IPACK) block
- Where
- Canada
- Volunteers
- 122 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Knee Arthroscopy, General Anesthesia
Patient Satisfaction and Postoperative Analgesia Between Subarachnoid Block With 2-chloroprocaine Versus General Anesthesia for Knee Arthroscopy
The study evaluates the efficacy of two different anesthetic techniques in patients undergoing unilateral knee arthroscopy. Participants will be randomized to receive either subarachnoid block with 2-chloroprocaine or general…
- Conditions
- Knee Arthroscopy, General Anesthesia, Subarachnoid Block
- Trial name
- NCT03173326
- Testing
- General anesthesia, Subarachnoid block
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Vanderbilt University Medical Center
Anesthesia, Epidural, Hypotension
Hypotension Prediction Index to Predict Epidural-labor Analgesia Induced Hypotension
The purpose of this pilot trial is to examine the feasibility and ease of use of monitoring by ClearSight in laboring and delivering patients with the intent to compare time-to-treatment of hypotension between conventionally…
- Trial name
- NCT05906368
- Testing
- ClearSight HPI Monitoring system, Standard of Care Blood Pressure Monitoring
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Postoperative Analgesia, Hip Surgery
PENG vs Deep Iliacus Plane Block in Intertrochanteric Femur Fractures
Intertrochanteric femur fractures are common in elderly patients and are associated with significant pain. Providing effective analgesia is clinically important both during positioning for spinal anesthesia and in the…
- Trial name
- NCT07513740
- Testing
- Intravenous Analgesia, Pericapsular nerve group (PENG) block, Deep Iliacus Plane Block (DIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Erzincan Binali Yildirim Universitesi
Lung Cancer, Pain, Postoperative
Pain Control After VATS Anatomical Pulmonary Resections
In patients undergoing minimally invasive thoracoscopic surgery (video-assisted thoracoscopic surgery, or VATS), moderate to severe post-operative pain may often be experienced.
- Conditions
- Lung Cancer, Pain, Postoperative, Thoracic Neoplasms
- Trial name
- NCT05993273
- Testing
- Epidural, ESP block, Cryoanalgesia
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- University Hospital Padova
Prostatectomy, Transversus Abdominis Plane Blockade
Ultrasound-assisted Bilateral Transversus Abdominis Plane Block for Open Prostatectomy
The purpose of this study is to compare the quality of a transversus abdominis plane blockade with an intravenous pain therapy with opioids.
- Conditions
- Prostatectomy, Transversus Abdominis Plane Blockade, Pain
- Trial name
- TAPPro (NCT01625572)
- Testing
- Transversus abdominis plane blockade, Morphine-patient-controlled-analgesia-device
- Where
- Germany
- Volunteers
- 66 people
- Sponsor
- Charite University, Berlin, Germany
Pregnant Women>37SA
EpiConCES - Epidural Lidocaine for Conversion to CaEsarean Section
The need to resort to a midwifery course work in cesarean is a common practice. Epidural analgesia for labor analgesia is practiced in 90% of women in obstetric work, as when the cesarean decision is taken course work in practice…
- Trial name
- EpiConCES (NCT02895022)
- Testing
- Lidocaine 2% adrénalinée, Epidural catheter, Caesarean section
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Anesthesia, Epidural
Epidural Pressure Waveform Recordings by the CompuFlo® Cath-Checker System
The purpose of this single arm, open label study will be to evaluate whether the dwell time of the epidural catheter, patients' position, the presence of active labor contractions and the priming volume of the epidural catheter…
- Trial name
- NCT04240912
- Testing
- CompuFlo Epidural Computer Controlled System
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- European e-Learning School in Obstetric Anesthesia
Heart Surgery Via Sternotomy, Post-operative Analgesia
Advantage of Tramadol in Local Analgesia Post-Sternotomy
Sternotomy, the reference approach for heart surgery, may induce profound and intense post-operative pain. One method of analgesia used is patient-controlled intravenous morphine.
- Trial name
- ATLAS (NCT02851394)
- Testing
- Levobupivacaine, tramadol
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Osteo Arthritis Knee, Gonarthrosis
The Impact of Single-shot Adductor Canal Block Versus Continuous Femoral Nerve Block on Rehabilitation After Total Knee Replacement
Total knee replacement (TKR) is considered the most effective and safe method of radical treatment of late stages of knee osteoarthritis.
- Trial name
- NCT05487053
- Testing
- Single-shot adductor canal block, Continuous femoral nerve block
- Where
- Russia
- Volunteers
- 220 people
- Sponsor
- Negovsky Reanimatology Research Institute
Caudal Block for Postoperative Analgesia
Comparison of Optic Nerve Sheath Diameter in Children Receiving Caudal Block According to Anesthetic Agents: Total Intravenous Anesthesia vs. Volatile Anesthesia
Caudal block is commonly used for postoperative analgesia in paediatric patients. A higher volume (1.5 ml/kg) of local anaesthetic for caudal block has been reported to not only increase the level of cranial spread but also…
- Trial name
- NCT04415905
- Testing
- Propofol, Sevoflurane
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Urodynamics, Acute Urinary Retention
Effects of Thoracic Epidural Anesthesia on Lower Urinary Tract Function
Acute urinary retention is one of the most common complications after surgery and anesthesia. Overfilling the bladder can stretch and damage the detrusor muscle, leading to atony of the bladder.
- Trial name
- NCT00790231
- Testing
- urodynamic procedure
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Anesthesia, Local Anesthesia
Can Caudal Dexmedetomidine Provide Effective Analgesia?
The goal of this clinical trial is to evaluate if caudal dexmedetomidine can provide effective analgesia during inguinoscrotal surgeries in pediatrics, if used caudally alone (and not as an adjunct to caudal bupivacaine).
- Trial name
- NCT05902780
- Testing
- Caudal Bupivacaine injection, Caudal Dexmedetomidine Injection
- Volunteers
- 50 people
- Sponsor
- Benha University
Pelvic Bone Injury, Pelvis Injury
RELIEVED (REgionaL anesthesIa PElVic fracturEs stuDy) Study. Regional Anesthesia (RA) Techniques for Pain Management in Pelvic Fractures: A Prospective, Monocentric, Pilot Cohort Study.
The goal of this observational clinical trial is to assess the impact of Regional Anesthesia (RA) techniques with the strongest anatomical and scientific support in controlling acute post-operative pain in pelvic/acetabular…
- Conditions
- Pelvic Bone Injury, Pelvis Injury, Acetabular Fractures, Acetabular Surgery
- Trial name
- RELIEVED (NCT07072286)
- Testing
- Regional Anesthesia, Multimodal analgesia
- Where
- Italy
- Volunteers
- 177 people
- Sponsor
- A.O.U. Città della Salute e della Scienza