Clinical trials: Anesthesia Complications
Bladder Tumors, Spinal Anesthesia
Magnesium vs. Dexmedetomidine in TURBT Under Spinal Anesthesia
This randomized controlled trial evaluated the effects of intraoperative intravenous magnesium sulfate versus dexmedetomidine on postoperative pain, analgesic consumption, hemodynamic stability, and respiratory function in…
- Conditions
- Bladder Tumors, Spinal Anesthesia, Postoperative Pain, Magnesium Sulfate
- Trial name
- TURBT (NCT07445451)
- Testing
- magnesium sulfate, Dexmedetomidine, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Neuromuscular Block, Residual, Pain
Methylprednisolone vs Dexamethasone: Effects on Sugammadex Reversal, Pain, and Nausea in Adults
This randomized controlled trial aims to compare the effects of intravenous methylprednisolone and dexamethasone on the reversal time of rocuronium by sugammadex in adult patients undergoing elective septoplasty or rhinoplasty.
- Conditions
- Neuromuscular Block, Residual, Pain, Postoperative Nausea
- Trial name
- NCT07187037
- Testing
- Methylprednisolone (MP), Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Postoperative Pain, Inferior Alveolar Nerve Block Failure
Evaluation of Systemic Inflammatory Index and Biomarkers in Relation to Inferior Alveolar Nerve Block Success and Postoperative Pain
This study aims to investigate the relationship between systemic inflammatory markers and the effectiveness of inferior alveolar nerve block anesthesia in patients undergoing dental treatment.
- Conditions
- Postoperative Pain, Inferior Alveolar Nerve Block Failure, Inflammation Biomarkers, Dental Anesthesia Complications
- Trial name
- NCT07163065
- Testing
- Inferior Alveolar Nerve Block Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- KEZBAN MELTEM ÇOLAK
Postoperative Nausea and Vomiting
Dexamethasone for the Prevention of Post-operative Nausea and Vomiting in Patients Undergoing Cesarean Sections
Patients who present for scheduled (non-emergent) cesarean section will be given either intravenous dexamethasone or placebo prior to receiving a duramorph containing spinal anesthetic.
- Trial name
- NCT01734161
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Pain, Acute, Anesthesia, Local
Intracervical Anesthesia and Pain Associated With Intrauterine Contraceptive Insertion
The primary aim of our study is to evaluate the effect of intracervical anesthesia on pain scores immediately following levonorgestrel-releasing intrauterine system (LNG-IUS) insertion in nulligravida women.
- Conditions
- Pain, Acute, Anesthesia, Local, IUD Insertion Complication
- Trial name
- NCT03111342
- Testing
- Anesthesia, Dry-needling
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Post Operative Pain
The Efficacy of SPSIPB on Postoperative Pain in Patients Undergoing Shoulder Surgery
Aim is to assess the postoperative analgesic efficacy of SPSIPB and its effect on opioid consumption in patients undergoing shoulder surgery.
- Trial name
- NCT05901129
- Testing
- Serratus posterior superior intercostal plane block (SPSIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Cumhuriyet University
Postoperative Pain
Comparison of the Efficacy of PENG Block in Combination With LFCN Block and Wound Infiltration
The ultrasound-guided approach for the blockade of articular branches of femoral and obturator nerves, pericapsular nerve group (PENG) block, is an effective method for postoperative analgesia in hip surgeries.
- Trial name
- NCT04681222
- Testing
- LFCN, Wound infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Derince Training and Research Hospital
Emergence Delirium, Pediatric Dental General Anesthesia
Pre-emptive Local Anesthesia and Emergence Behavior After Pediatric Dental General Anesthesia
This study will evaluate whether pre-emptive local anesthesia improves early recovery after ambulatory pediatric dental general anesthesia.
- Conditions
- Emergence Delirium, Pediatric Dental General Anesthesia, Postoperative Recovery
- Trial name
- PEDLA-QOR (NCT07604337)
- Testing
- Pre-emptive Local Anesthesia, Articaine Hydrochloride With Epinephrine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- seher orbay yasli
Pectus Excavatum, Chest Deformities
SPSIPB Versus SAPB for Postoperative Analgesia After Minimally Invasive Repair of Pectus Excavatum
This prospective observational cohort study will compare postoperative analgesic outcomes in patients undergoing minimally invasive repair of pectus excavatum.
- Trial name
- NCT07697222
- Testing
- Postoperative Analgesia Protocol, Bispectral Index Monitoring, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Marmara University
Lower Extremity Problem, Gynecologic Disease
Comparison of the Effect of Remimazolam and Propofol on Perioperative Hypothermia Under Spinal Anesthesia
After dividing the patients into two groups, sedation is performed with propofol and remimazolam, respectively, after spinal anesthesia. Compare the patient's body temperature change after surgery.
- Conditions
- Lower Extremity Problem, Gynecologic Disease, Urinary Tract Disease
- Trial name
- NCT05574257
- Testing
- Propofol, Remimazolam
- Where
- South Korea
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Anesthesia, Peroperative Complication
Respiratory Management of Children Under Anaesthesia
Ventilation management in paediatric anaesthesia remains difficult because of the wide range of age and weight, and therefore practices are heterogeneous.
- Trial name
- PEDIAVENT (NCT04020900)
- Testing
- Respiratory management
- Where
- France
- Volunteers
- 701 people
- Sponsor
- Hospices Civils de Lyon
Carotid Stenosis, Carotid Endarterectomy
Hemathologic and Imagiologic Predictors of Stroke During Carotid Endarterectomy With Regional Anesthesia
Establish and validate biomarkers which improve the predictive value of current risk stratification models for patients benefiting from carotid revascularization, outperform existing biomarkers, and reach clinical application…
- Trial name
- NCT04327492
- Testing
- Biomarker - FGF 23; troponin I; PCR - high sensitivity; BNP
- Where
- Portugal
- Volunteers
- 272 people
- Sponsor
- Universidade do Porto
Pharmacological Action, Post Operative Pain
The Postoperative Lidocaine and Ketamine Effects on Morphine Requirement in Bariatric Surgery
The goal of this observational study is to evaluate the quality of postoperative analgesia in a group of obese patients schedule to bariatric surgery under TIVA Opiod-free after to receive lidocaine and ketamine perfusion.
- Conditions
- Pharmacological Action, Post Operative Pain, Opioid Use, Obesity, Morbid
- Trial name
- NCT05591105
- Testing
- Control Group
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Tiva Group
Anesthesia, General
Maternal Voice on Anesthetic Emergence Period
Mother spend a large amount of time with their children. It is assumed that mother contributes to their neurological development not only with visual stimuli, but also with auditory stimuli.
- Trial name
- MatherVoice (NCT02860377)
- Testing
- recorded maternal voice, recorded stranger's voice
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Daegu Catholic University Medical Center
Peripheral Vascular Disease
Lower Extremity Regional Anesthesia and Infrainguinal Bypass Grafting
In this investigation, the investigators will attempt to demonstrate that patients who have received nerve blocks (regional anesthesia) prior to open surgical vascular bypass of the lower extremities (infrainguinal bypass…
- Trial name
- NCT01803165
- Testing
- Single shot femoral and sciatic nerve block
- Sponsor
- University of Nebraska
Coxarthrosis, Pain, Postoperative
Lumbar ESPB in Hip Replacement Surgery
In this study, continuous erector spinae plane block (ESPB) will be compared to continuous epidural analgesia in patients undergoing elective hip replacement surgery.
- Conditions
- Coxarthrosis, Pain, Postoperative, Pain, Acute, Pain, Chronic
- Trial name
- ESPB_HIP (NCT06282666)
- Testing
- Spinal anesthesia, lumbar erector spinae plane block, Epidural analgesia
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Lublin
Cholelithiases, Cholecystitis
Ultrasound-Guided Rectus Sheath Block Versus Local Infiltration
Laparoscopic cholecystectomy is associated with significant postoperative pain originating from trocar sites, pneumoperitoneum, and visceral irritation.
- Conditions
- Cholelithiases, Cholecystitis, Postoperative Pain
- Trial name
- NCT07582029
- Testing
- Rectus Sheath Block, Local Anesthetic Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Behavior Problem
Intranasal Dexmedetomidine or Esketamine for Negative Postoperative Behavioral Changes in Children
The goal of this clinical trial is to learn whether intranasal dexmedetomidine or esketamine given before anesthesia can reduce negative postoperative behavioral changes in children undergoing day surgery.
- Trial name
- PEDI-NPOBCs (NCT07570160)
- Testing
- Dexmedetomidine, Esketamine, Normal Saline
- Where
- China
- Volunteers
- 342 people
- Sponsor
- Nanjing Children's Hospital
Perioperative/Postoperative Complications
Perioperative Risk Calculator
The aim of this project is to develop a machine-learning model for calculating the risk of postoperative complications. In addition to the data collected during the premedication, the model will include all intraoperative values…
- Trial name
- PROTECT (NCT04092933)
- Volunteers
- 175,559 people
- Sponsor
- Technical University of Munich
Smoking Cessation, Surgical Complications
Perioperative Smoking Cessation BUndle in a Tertiary Care Hospital - Can Turning Virtual Improve Outcomes?
Smoking continues to be a burden to the healthcare system in Canada. It is well-known that smokers suffer more complications and higher risk of mortality after surgery than non-smokers.
- Trial name
- BuTT-Out (NCT04487548)
- Testing
- Remote smoking cessation bundle
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Fraser Health