Clinical trials: Anesthesia Conduction
Shoulder Pain, Regional Anesthesia Morbidity
Intra- Versus Extraplexic Catheter Placement for Continuous Interscalene Brachial Plexus Block
Continuous interscalene brachial plexus block consists of inserting a catheter directly within the brachial plexus in the interscalene groove, between the middle and anterior scalene muscles, which is then infused with local…
- Conditions
- Shoulder Pain, Regional Anesthesia Morbidity, Shoulder Arthritis
- Trial name
- NCT02433561
- Testing
- Intraplexic catheter location (Contiplex® C, B. Braun Melsungen, AG), Extraplexic catheter location (Contiplex® C, B. Braun Melsungen, AG)
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Brachial Plexus Anesthesia, Analgesia
Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia
Adding dexamethasone to local anesthetic will significantly prolong duration of brachial plexus anesthesia and analgesia.
- Trial name
- NCT01739270
- Testing
- supraclavicular brachial plexus block
- Where
- Croatia
- Volunteers
- 55 people
- Sponsor
- University Hospital Dubrava
Postoperative Pain, Regional Anesthesia
Comparison of OSTAP, ESP Block,Injection of Local Anesthetic to Trocar Insertion for Elective Laparoscopic Cholecystectomy
Main purpose of this prospective single center randomized study is to compare the analgesic effect of ultrasound guided Unilateral Oblique Subcostal Transversus Abdominis Plane (TAP),unilateral Erector Spinae Plane (ESP) blocks…
- Trial name
- NCT03719157
- Testing
- Unilateral ESP Block, Unilateral OSTAP Block, Injection of Local Anesthetic to Trocar Insertion
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Postoperative Pain, Spinal Fusion Surgery
TLIP Block Versus Retrolaminar Block on Quality of Recovery After Posterior Lumbar Spine Fusion Surgery
This prospective randomized controlled study aims to compare the effects of ultrasound-guided thoracolumbar interfascial plane (TLIP) block versus retrolaminar block on postoperative quality of recovery in patients undergoing…
- Conditions
- Postoperative Pain, Spinal Fusion Surgery, Degenerative Lumbar Spine Diseases
- Trial name
- TLIP-RLB-QoR (NCT07609212)
- Testing
- Thoracolumbar interfascial plane block, Retrolaminar block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Regional Anesthesia Morbidity, Nephrectomy
Comparison of Erector Spinae Plane Block and Intravenous Analgesic in Nefrectomy
The efficacy of erector spinae plane block versus intravenous analgesics compared relate to the morphine consumptions
- Trial name
- NCT04686890
- Testing
- erector spinea plane block administered preoperative open nephrectomy, intravenous analgesic ( 1 mg/kg tramadol + non-steroid antiinflamatuar paracetamol )drug + 10 mg.kg
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Kocaeli University
Cutaneous Sensory Blockade
Effects of Injection Volume and Site on Sensory Distribution After Rectus Sheath Block
This randomized controlled study aims to evaluate the effects of local anesthetic injection volume and injection site on cutaneous sensory distribution following ultrasound-guided rectus sheath block (RSB).
- Trial name
- RSB-SENSE (NCT07876297)
- Testing
- Ultrasound-Guided Upper Rectus Sheath Block (20 mL), Ultrasound-Guided Upper Rectus Sheath Block (30 mL), Ultrasound-Guided Middle Rectus Sheath Block (20 mL)
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Chiang Mai University
Modified Radical Mastectomy, Post Operative Pain, Acute
Comparıson of Analgesıc Effıcacy of Dıfferent Volumes of Serratus Posterior Superıor Intercostal Plane Block After Modıfıed Radıcal Mastectomy Surgery
The aim of researchers is to compare the effects of three different local anesthetic concentrations and volumes on opioid consumption, postoperative analgesic efficacy, and pain scores during ultrasound-guided SPSIP blocks in…
- Conditions
- Modified Radical Mastectomy, Post Operative Pain, Acute, Facial Plane Blocks
- Trial name
- NCT07670078
- Testing
- Serratus Posterior Superior Intercostal Plane (SPSIP) block 40 ml of 0.1875% bupivacaine, Serratus Posterior Superior Intercostal Plane (SPSIP) 50 ml of 0.15% bupivacaine, Serratus Posterior Superior Intercostal Plane (SPSIP) 30 ml of 0.25% bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Cumhuriyet University
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
Onset Time of Nerve Block: A Comparison of Two Injection Locations in Patients Having Lower Leg/ Foot Surgery
The purpose of this study is to compare injecting local anesthetic (numbing medication) in different patterns around a major nerve in the leg.
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/or Foot
- Trial name
- NCT01542840
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Spinal Anesthesia, Total Knee Arthroplasty
Frontal QRS Axis Changes in Patients Undergoing Total Knee Arthroplasty With Spinal Anesthesia (FQRS-TKA)
This prospective, single-center, observational study aims to evaluate changes in the frontal QRS axis on ECG before and after spinal anesthesia in patients undergoing total knee arthroplasty.
- Trial name
- FQRS-TKA (NCT07112313)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sevim Şenol Karataş
Pain Management
Regional Anesthesia to Reduce Opioid Use Following Functional Endoscopic Sinus Surgery
Opioids are prescribed for moderate to severe pain disorders; however, there are contraindications and side effects that are common to all opioids.
- Trial name
- NCT03757715
- Testing
- Bupivacaine, Dexamethasone
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Alabama at Birmingham
Postoperative Pain, Opioid Use
Continuous Serratus Anterior Blockade for Sternotomy
This is a pilot study to assess the feasibility of a full study. The purpose is to assess the analgesic effectiveness of the serratus anterior plane (SAP) block following cardiac surgery.
- Conditions
- Postoperative Pain, Opioid Use, Quality of Life
- Trial name
- Cardiac-SAP (NCT04648774)
- Testing
- Serratus anterior plane (SAP) block
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority
Post-operative Pain, Total Shoulder Arthroplasty
LIBERATE - LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs
This will be a single-center, prospective, randomized controlled cross-sectional study comparing interscalene brachial plexus block with liposomal bupivacaine versus bupivacaine with epinephrine and PF dexamethasone in patients…
- Conditions
- Post-operative Pain, Total Shoulder Arthroplasty, Osteoarthritis of the Shoulder, Pain Management
- Trial name
- NCT03887650
- Testing
- Liposomal Bupivicaine 1.3%, Bupivacaine 0.5%
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Hartford Hospital
Femur Fracture, Hip Surgery
Pericapsular Nerve Group (PENG) Block on Pain During Participant Positioning for Spinal Anesthesia in Hip Fracture Surgery
Hip fracture surgery is a common orthopedic procedure, especially in elderly patients. These fractures are quite common in adults over the age of 65, and the one-year mortality rate ranges from 12% to 37%.
- Trial name
- NCT06813755
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Marmara University
Hip Fractures, Delirium
ED Ultrasonographic Regional Anesthesia to Prevent Incident Delirium in Hip Fracture Patients
Hip fractures are common, costly and affect older people - Canadians spend 1 billion dollars to treat hip fractures each year. Unfortunately, as many as two-thirds of hip fracture cases suffer a complication known as delirium, or…
- Trial name
- EDU-RAPID (NCT02892968)
- Testing
- Fascia-Iliaca Block(FIB), Femoral Nerve Block(FNB)
- Where
- Canada
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Pain, Postoperative, Osteoarthritis, Knee
Comparing Local Anesthetic Injections to Nerve Blocks for Pain Control After Total Knee Replacement
Why are we doing this study? People who have knee replacement surgery often feel pain afterward. Doctors use different methods to control this pain.
- Conditions
- Pain, Postoperative, Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Trial name
- LIA-PNB-TKA (NCT07744503)
- Testing
- Continuous Femoral and Sciatic Nerve Block (Ropivacaine), Local Infiltration Analgesia (Ropivacaine, Ketorolac, Epinephrine)
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Christopher Male
Hypotension, Regional Anesthesia Morbidity
Spinal Anesthesia Related Hypotension in SARS-CoV-2 (COVID-19) Pregnant Patients
Since the onset of COVID-19, recommendations suggest the use of neuraxial anesthesia, if possible, over general anesthesia for cesarian section to avoid the risks of aerosolization associated with tracheal intubation and…
- Conditions
- Hypotension, Regional Anesthesia Morbidity, SARS-CoV2 Infection
- Trial name
- NCT05085652
- Testing
- spinal anesthesia induced hypotension in SARS-CoV-2 patients.
- Where
- Turkey (Türkiye)
- Volunteers
- 251 people
- Sponsor
- Ankara City Hospital Bilkent
Postoperative Nausea and Vomiting
Preoperative Oral Carbohydrate for Nausea and Vomiting Prevention During Cesarian Section
Post-operative nausea and vomiting (PONV) in women undergoing subarachnoid anesthesia for Caesarean section is an important clinical problem.
- Trial name
- POC-NaVoP (NCT04069806)
- Testing
- preoperative oral carbohydrate, preOp
- Where
- Poland
- Volunteers
- 140 people
- Sponsor
- Pomeranian Medical University Szczecin
CHD - Congenital Heart Disease
Bilateral Ultrasound Guided Superficial Parasternal Intercostal Plane Block Versus Erector Spinae Plane Block
Group (A): This group will receive fentanyl infusion at a dose of (0.5μg/kg/h) all through the whole operation plus ultrasound guided bilateral superficial parasternal intercostal Plane block which will be done by injecting…
- Trial name
- NCT06958120
- Testing
- superficial parasternal intercostal Plane block, Erecto spinea plane block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Pain, Postoperative
Regional Anesthesia for Head and Neck Reconstruction
By utilizing regional anesthesia blocks at the surgery tissue donor sites, it can potentially reduce post-operative pain while also reducing the use of opioids.
- Trial name
- NCT04304716
- Testing
- Regional Anesthesia
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Breast Cancer, Acute Pain
Mid-point Transverse Process to Pleura Block for Breast Cancer Surgery: A Randomized Controlled Trial
This study will compare the analgesic effects of midpoint transverse process to pleura (MTP) block to control as well as thoracic paravertebral block.
- Conditions
- Breast Cancer, Acute Pain, Anesthesia
- Trial name
- NCT03713255
- Testing
- PVB group, MTP block group, Control Group
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Ottawa Hospital Research Institute
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