Clinical trials: Anesthesia Conduction
Breast Cancer, Postoperative Pain
Effectiveness of Ultrasound Guided Erector Spinae Plane Block Against Ultrasound Guided Serratus Anterior Block in Modified Radical Mastectomy
The aim of this study is to compare and evaluate the safety and analgesic efficacy of ultrasound guided ESP block and ultrasound guided serratus anterior plane block in patients undergoing modified radical mastectomy.
- Trial name
- NCT04606147
- Testing
- Serratus Anterior Plane Block, Erector spinae plane block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Pain, Postoperative, Developmental Dysplasia of the Hip
Postoperative Analgesic Effect of Two Peripheral Nerve Blocks for Hip Surgery in Pediatrics
Hip joint surgery for developmental dysplasia of the hip (DDH) in children is extremely painful and associated with considerable postoperative pain despite the use of systemic opioids.
- Conditions
- Pain, Postoperative, Developmental Dysplasia of the Hip, Regional Anesthesia Morbidity
- Trial name
- NCT05348421
- Testing
- FTPB, PENG Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Lower Extremity Fracture, Surgical Fracture Repair
Pre-Incision Peripheral Nerve Blocks for Lower Extremity Fracture Surgery in Older Adults
Fractures of the lower leg are especially difficult for older adults. They are more likely to have serious complications, require longer healing times, and have a higher risk of death This occurs because their bodies cannot…
- Conditions
- Lower Extremity Fracture, Surgical Fracture Repair, Orthopaedic Trauma, Orthogeriatric Fractures
- Trial name
- NCT07217626
- Testing
- Local anesthesia injections
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Maryland, Baltimore
Anxiety, Stress (Psychology)
Cellphone Access for Lowered Maternal Anxiety and Stress in Cesarean Sections
This study looks at whether allowing mothers to use their personal cellphone during a planned cesarean section (C-section) under spinal anesthesia can reduce stress and anxiety and improve their overall birth experience.
- Trial name
- CALMAS-CS (NCT07759726)
- Testing
- Cell Phone Use
- Where
- Lebanon
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Beirut Arab University
Pain Management in Breast Surgery, Pain After Surgery
Comparison of the Analgesic Efficacy of Erector Spinae Plane Block in Breast-Conserving Surgery Versus Serratus Anterior Block Combined With Additional Pecto-Intercostal II Block
This prospective randomized study will compare the effects of Erector Spinae Plane Block (ESPB) and Serratus Anterior Plane Block combined with Pectoral Nerve Block Type II (SAPB + PECS II) on intraoperative analgesia and…
- Conditions
- Pain Management in Breast Surgery, Pain After Surgery, Regional Anaesthesia
- Trial name
- NCT07368413
- Testing
- SAPB + PECS II Technique, Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kayseri City Hospital
Anesthesia, Anesthesia, Local
A Study in Healthy Male Volunteers to Investigate the Safety and Tolerability of a Single Dose of Neosaxitoxin Alone and in Combination With Bupivacaine (With and Without Epinephrine) for Brachial Plexus Blockade
Neosaxitoxin is a new compound that is in clinical development as local anesthetic for surgical anesthesia and postoperative analgesia.
- Conditions
- Anesthesia, Anesthesia, Local, Analgesia
- Trial name
- NCT03399435
- Testing
- Neosaxitoxin combined with bupivacaine low and epinephrine (T1), Bupivacaine low combined with epinephrine (C1), Bupivacaine high combined with epinephrine (C2)
- Where
- Netherlands
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Cardiac Surgery, Postoperative Pain
Combine Serratus Anterior Plane Block Versus Erector Spinae Plane Block in Coronary Bypass Surgery
Even though Erector Spinae Plane (ESP) Block is shown to be efficient in cardiac surgery, the Combine Serratus Anterior Plane (CSAP) Block is still controversial if it has an efficient analgesic effect for sternotomy and drain…
- Conditions
- Cardiac Surgery, Postoperative Pain, Regional Anesthesia Morbidity
- Trial name
- NCT05308797
- Testing
- ESP block, CASP block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Breast Surgery
Erector Spinae Versus Paravertebral Nerve Blocks for Breast Surgery
Following painful surgical procedures of the breast, postoperative analgesia is often provided with a paravertebral nerve block (PVB).
- Trial name
- NCT03549234
- Testing
- Erector Spinae (single injection), Paravertebral (single injection)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Diego
Coronary Artery Disease, Postoperative Pain
Five Multimodal AI Configurations Versus Expert Anaesthesiologists for Classifying Pecto-Intercostal Fascial Plane Block Spread in CABG
This prospective observational cohort with a nested archived-image reader study compared the sonographic pecto-intercostal fascial plane block classifications of five general-purpose multimodal artificial-intelligence…
- Trial name
- NCT07581678
- Testing
- Pecto-Intercostal Fascial Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Nerve Block, Nerve Blocks
Blast-related Regional Anaesthesia and Peripheral nerVe Injury Evaluation
This randomized study will examine whether ultrasound-guided regional anaesthesia (a nerve block) contributes to new or worsening peripheral nerve problems after blast-related limb trauma.
- Conditions
- Nerve Block, Nerve Blocks, Nerve Injury, Blast Injury
- Trial name
- BRAVE (NCT07879508)
- Testing
- Standardized Multimodal Analgesia, Ultrasound-Guided Regional Anaesthesia
- Volunteers
- 150 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Anesthesia
URAISE: Ultrasound Regional Anaesthesia Interpretation Skill Evaluation
Prospective study based on psychometric principles.# To generate a validated test of ultrasound guided regional anaesthesia that can used to differentiate reliably between users of different skill levels.
- Trial name
- URAISE (NCT05668689)
- Testing
- Preliminary testing, Psychometric main study testing (Phase 5)
- Where
- 6 sites in United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Postoperative Pain, Laparotomy
M-TAPA vs RSB in Midline Abdominal Incision Laparotomy
The aim is to compare the postoperative analgesic effects of Modified ThoracoAbdominal nerve block through Perichondrial Approach (M-TAPA) versus Rectus Sheath Block (RSB) in patients undergoing laparotomy with midline abdominal…
- Trial name
- NCT07233629
- Testing
- Modified thoracoabdominal nerve block through perichondrial approach (M-TAPA), Rectus Sheath Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cumhuriyet University
Interscalene Block, Superficial Cervical Block
Comparison Of The Effects Of Regional Anesthesia On Brain And Carotid Artery Oxygenation In Shoulder Surgery
The aim of our study was to compare the effects of interscalene block alone and the combination of interscalene block and superficial cervical block on cerebral oxygenation, carotid artery diameter, intraoperative hemodynamics…
- Conditions
- Interscalene Block, Superficial Cervical Block, Cerebral Perfusion, Shoulder Surgeries
- Trial name
- NCT07398352
- Testing
- Interscalene brachial plexus block, Interscalene brachial plexus block and superficial cervical plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Knee Prosthesis, Pain, Procedural
Comparison of Different Analgesic Nerve Blocks in Total Knee Replacement Surgery
The goal of this observational study is to compare the equivalent analgesic efficacy of three regional anesthesia techniques in total knee replacement surgery.
- Trial name
- NCT06422585
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Regional Anesthesia, Anxiety
Uncontrolled Disinformation About Regional Anesthesia and Pregnant Patients.
Nowadays, hundreds of information about regional anesthesia are accessed from any internet search engine when a question is written about the methods of anesthesia that can be applied during C/S.
- Conditions
- Regional Anesthesia, Anxiety, Social Media Addiction, Spinal Anesthesia
- Trial name
- NCT05416541
- Testing
- social media
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Cataract, Vitreous Disorder
Comparison of Two Surgical Sequences "Cataract Surgery Then Vitrectomy" Versus "Vitrectomy Then Cataract Surgery" Under Local-regional Anesthesia
Cataracts and vitreo-retinal conditions are frequently associated and can lead to a combined surgery to treat both diseases at the same time.
- Trial name
- VICAR (NCT05583331)
- Testing
- Cataract surgery, Vitrectomy
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Elsan
Regional Anesthesia Morbidity
Dexmedetomidine in IVRA
A prospective randomized controlled double-blinded study will be conducted on 90 patients assigned randomly into three equal groups,
- Trial name
- NCT05123170
- Testing
- Dexmedetomidine Injectable Solution [Dexdomitor], Lidocaine IV
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Indication for Renal and/or Adrenal Surgery
Merits of Continuous Paravertebral Block in the Management of Renal/Adrenal Surgery by Laparotomy
The paravertebral block is an alternative in the analgesia epidural the major interest of which lives in the catheterisation of the paravertébral space allowing to assure/insure an one-sided continuous analgesia.
- Trial name
- BPV (NCT01023854)
- Testing
- Continuous Paravertebral block
- Where
- France
- Volunteers
- 41 people
- Sponsor
- University Hospital, Brest
Postoperative Pain, Total Knee Arthroplasty
Comparing ACB+IPACK and ACB+BiFeS Block Combinations for Analgesia in Total Knee Arthroplasty
Total knee arthroplasty (TKA) is associated with severe postoperative pain that delays mobilization, prolongs hospital stay, and reduces patient satisfaction.
- Trial name
- NCT07561333
- Testing
- ACB+IPACK Group, ACB+BiFeS Group
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Hitit University
Osteoarthritis of Hip, Regional Anesthesia
Continuous Lumbar Plexus Block With and Without Parasacral Block in Patients Undergoing Total Hip Replacement
The purpose of this research study is to evaluate the analgesic efficacy of adding a single shot parasacral (sciatic) nerve block to a continuous lumbar plexus block in patients undergoing total hip replacement.
- Conditions
- Osteoarthritis of Hip, Regional Anesthesia, Other Acute Postoperative Pain, Total Hip Arthroplasty
- Trial name
- NCT02161484
- Testing
- Continuous Lumbar Plexus Block, Parasacral Nerve Block, Ropivacine 0.2%
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rita Merman
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