Clinical trials: Anesthesia Effectiveness
Agitation States as Acute Reaction to Gross Stress
Efficacy of External Nasal Nerve Block in Prevention of Postoperative Agitation Following Nasal Surgeries
Emergence agitation following general anaesthesia may lead to serious complications like self-extubation or removal of catheters, which can lead to hypoxia, aspiration pneumonia, bleeding or reoperation.
- Trial name
- NCT03069027
- Testing
- External nasal nerve block, saline adrenaline, Xylocaine, adrenaline
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al Jedaani Hospital
Emergence Agitation
Efficacy of Low Dose Propofol Given at the End of Sevoflurane Anesthesia for Prevention of Emergence Agitation in Pediatric Patient Undergoing MRI Scan
The goal of this clinical trial is to compare Efficacy of low dose propofol(0.5 mg/kg) vs placebo given at the end of sevoflurane anesthesia for prevention of emergence agitation in pediatric patient undergoing MRI scan.
- Trial name
- NCT06218680
- Testing
- Propofol, Normal saline
- Where
- Thailand
- Volunteers
- 134 people
- Sponsor
- Khon Kaen University
Arthroscopic Shoulder Surgery
Effects of Technique on the Local Anesthetic Dose Required for Interscalene Brachial Plexus Block
Interscalene brachial plexus block (ISBPB) is a common nerve block given to patients who are undergoing shoulder surgery. This block has a low, but still significant, rate of complications.
- Trial name
- NCT00731146
- Testing
- Ultrasound Minimum Effective Anesthetic Volume, Nerve Stimulator Minimum Effective Anesthetic Volume
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Sunnybrook Health Sciences Centre
Anesthesia
Anesthetic Efficacy of X-tip Intraosseous Injection
Hypothesis: X-tip intraosseous is an effective supplementary injection in mandibular hot teeth as well as Periodontal Ligament (PDL) injection Purposes: Comparing the anesthetic efficacy of X-tip intraosseous and PDL injection in…
- Trial name
- NCT01214369
- Testing
- Type of Supplementary Injection
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Diaphragm Paralysis Due to Local Anesthesia, Anterior Suprascapular Nerve Block
Anterior Suprascapular Nerve Block is an Effective and Diaphragm Protective Approach for Arthroscopic Shoulder Surgery
Interscalene block is still the gold standard in shoulder surgery analgesia. The most important side effect is diaphragm paralysis due to the phrenic nerve being affected.
- Conditions
- Diaphragm Paralysis Due to Local Anesthesia, Anterior Suprascapular Nerve Block, Analgesia, Arthroscopic Shoulder Surgery
- Trial name
- NCT04626869
- Testing
- Evaluation of Diaphragm Movement
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alper Tunga Dogan
Dental Implants, Local Anesthesia
Comparison of Anesthetic Efficacy and Safety Between Nerve Block and Infiltrative Technique for Mandibular Posterior Implant Placement.
The goal of this triple blind randomized clinical trial is to compare the safety, efficacy and postoperative pain between the inferior dental nerve block (IDNB) and the infiltrative technique (TINF) in the placement of mandibular…
- Trial name
- NCT06641232
- Testing
- Comparison of anesthetic efficacy and safety between nerve block and infiltrative technique for mandibular posterior implant placement.
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Postoperative Pain, Caesarean Section
Intraperitoneal Hydrocortisone for Postoperative Pain and CRP Following Caesarean Section
The purpose of this study is to evaluate the clinical efficacy of intraperitoneal hydrocortisone 100 mg administration in reducing postoperative pain and inflammatory response in patients undergoing elective Caesarean section…
- Conditions
- Postoperative Pain, Caesarean Section, Peritoneal Inflammation
- Trial name
- NCT07892547
- Testing
- hydrocortisone, Nornal Saline
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Raditsya Mada Gautama, MD
Shivering Caused by Spinal Anesthesia
Dexmedetomidine in Post Spinal Anesthesia Shivering
This study evaluated the effect of dexmedetomidine iv in three different doses in the treatment of shivering in patients undergoing minor elective abdominal surgery under spinal anesthesia, in comparison with intravenous…
- Trial name
- NCT02382432
- Testing
- Pethidine 0.4mg/kg, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Badly Decayed Lower First Primary Molars in Children
Anesthetic Efficacy Of 4% ArtpharmaDent Versus 2% Mepecaine-L in Extraction of Lower First Primary Molars
parallel technique will be done where the investigator (will be blinded) will give one type on anesthesia then performing the extraction and evaluating the intraoperative pain ,the same procedure will be done for the other type…
- Trial name
- NCT03942991
- Testing
- articaine, Mepivacaine 2% Injection
- Volunteers
- 20 people
- Sponsor
- Cairo University
Pain, Pacemaker Ddd
Evaluation of the Effectiveness of the Supraclavicular Block Associated With a Pecs Blocks I to Ensure Analgesia When Placing a Pacemaker
Pacemakers are currently placed at the Erasmus Hospital under local anesthesia performed by the surgeon, and the amount of local anesthetic agents sometimes reach the maximum permitted doses, with a risk of systemic toxicity.
- Trial name
- NCT04067024
- Testing
- Local anesthesia made by surgeon, Regional anesthesia group
- Where
- Belgium
- Volunteers
- 31 people
- Sponsor
- Erasme University Hospital
Periodontitis, Gingivitis and Periodontal Diseases
Effectiveness of Intraseptal Anesthesia for Periodontal Surgical Procedures
The primary aim of this study is to evaluate the efficacy of intraseptal anesthesia using 0.3 mL of 4% articaine with 1:100,000 epinephrine (4% Ar+Ep) for periodontal flap surgery in patients with periodontitis and for…
- Trial name
- NCT07212270
- Testing
- periodontal flap surgery, gingivectomy and gingivoplasty
- Where
- Serbia
- Volunteers
- 60 people
- Sponsor
- University of Belgrade
Postoperative Pain, Cesarean Section
Intrathecal Morphine 75 mcg Versus 100 mcg for Post-Cesarean Analgesia: A Randomized Double-blind Trial
This study evaluates the efficacy and safety of two different doses of intrathecal morphine (75 mcg versus 100 mcg) for postoperative analgesia in patients undergoing elective cesarean delivery under spinal anesthesia.
- Conditions
- Postoperative Pain, Cesarean Section, Obstetric Anesthesia
- Trial name
- ITM-CESAREAN (NCT07516717)
- Testing
- Intrathecal Morphine
- Where
- Venezuela
- Volunteers
- 240 people
- Sponsor
- Hospital Universitario de Caracas
Post Operative Pain
Efficacy of Parecoxib Combined With Paracetamol in Mastectomy
Patients undergoing breast cancer surgery experience persistent pain after surgery and subsequent development of chronic pain. Parecoxib or paracetamol has been reported to reduce postoperative pain in mastectomy.
- Trial name
- NCT05757388
- Testing
- Parecoxib + paracetamol, Normal saline
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Khon Kaen University
Analgesia, Arthropathy of Knee
Comparison of Two Different Regional Analgesia Techniques for Patients Undergoing Total Knee Arthroplasty
The objective of this clinical trial is to compare two regional analgesia techniques in patients undergoing total knee arthroplasty: IPACK (Infiltration of local anesthetic between the Popliteal Artery and Capsule of the Knee) vs…
- Conditions
- Analgesia, Arthropathy of Knee, Postoperative Pain
- Trial name
- PIPACK (NCT06179641)
- Testing
- Selective tibial nerve block, IPACK block
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Thoracic Cancer
OFA in Thoracic Surgery
to investigate the efficacy and safety of opioid-free anesthesia for non-small-cell lung cancer resection and its underlying clinical value
- Trial name
- NCT05063396
- Testing
- opioid free anesthesia, Opioid-sparing anesthesia
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Shanghai Zhongshan Hospital
Anesthesia, Dental
Study of NV-101 for Efficacy, Pharmacodynamics, and Safety in Dental Patients Undergoing Mandibular Procedures
This Phase 3 study is designed as a multicenter, randomized, blinded, controlled study to evaluate the efficacy, pharmacodynamics, and safety of NV-101 administered as a submucosal injection following completion of a restorative…
- Trial name
- NCT00309361
- Testing
- Phentolamine Mesylate (NV-101)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Novalar Pharmaceuticals, Inc.
No Disease State or Condition
Pain Study to Assess Local Anesthetic Efficacy and Safety of CTY-5339 on Gingival Mucosal Tissue in Normal Volunteers
The purpose of this study is to determine if the topical application to gingival tissue of the combination of benzocaine and tetracaine has a longer duration of local anesthetic activity than benzocaine alone.
- Trial name
- NCT03233737
- Testing
- One spray CTY-5339-A, One spray CTY-5339-CB, One spray CTY-5339-P
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cetylite Industries
Hip Surgery Corrective, Anesthesia; Functional
Effectiveness of Fascia Iliaca Nerve Block for Post Hip Arthroscopy
There is currently no standard of care or best practice for managing post-operative pain for patients undergoing hip arthroscopy. Perioperative pain with these procedures can be substantial.
- Trial name
- NCT02717728
- Testing
- Drug group Fascia iliaca nerve block
- Where
- United States
- Sponsor
- Boston Children's Hospital
Anesthesia, General
Comparison of the Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616; Org 25969) in Elderly Participants With Adult Participants (MK-8616-029)
The purpose of the study is to compare the effectiveness, safety and pharmacokinetics of sugammadex in participants 65 and over with participants under 65. There is no hypothesis defined for the study.
- Trial name
- NCT00474617
- Testing
- Sugammadex, Rocurium
- Volunteers
- 162 people
- Sponsor
- Merck Sharp & Dohme LLC
Chest Pain, Pain, Procedural
Evaluation of the Effectiveness of Two Methods of Regional Anesthesia During S-ICD Implantation Procedure.
Our study consists of a combination of regional blockade ('local' anesthesia) of the anterior and lateral chest wall in the form of a thin needle prick and the supply of local anesthetic drugs to the area of the relevant chest…
- Conditions
- Chest Pain, Pain, Procedural, Pain, Postoperative, Analgesia
- Trial name
- NCT06520150
- Testing
- Regional anaesthetic combined fascial plane block, Ropivacaine 0.125% Injectable Solution +Lignocaine 0,25% Injectable Solution
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
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