Clinical trials: Anesthesia Effectiveness
Post Operative Pain, Cesarean Section Complications
Postoperative Analgesic Efficacy of Trans Abdominis Plane Block
Transverse abdominis plane (TAP) block is an effective method to manage postoperative pain in patients with midline abdominal wall incisions.
- Trial name
- NCT05831501
- Testing
- Trans abdominis plane block
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Armed Forces Hospital, Pakistan
Pancreatic Neoplasms, Anesthesia
Evaluation of Prehabilitation as a Strategy to Minimize Surgical Risk in Pancreatic Surgery: Efficacy and Determining Factors.
Several studies in major abdominal surgery demonstrated that preoperative optimization of surgical patients through prehabilitation is associated with fewer postoperative complications.
- Trial name
- NCT05489419
- Testing
- Multimodal Prehabilitation
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- Hospital Clinic of Barcelona
Anesthesia
The Minimum Effective Concentration of Lidocaine for Ultrasound-guided Axillary Block for Arterio-venous Fistula Creation Surgery
The arteriovenous fistula creation (AVF creation) surgery is essential among patients with end stage renal disease who require hemodialysis.
- Trial name
- NCT05063578
- Testing
- Lidocaine 2% Injectable Solution
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Far Eastern Memorial Hospital
Consent Forms, Anesthesia
Effectiveness of Large Language Model for Anaesthesia and Procedural Consent
Patient understanding of anaesthesia risks remains inconsistent due to time constraints, language barriers, and variable clinician communication styles.
- Conditions
- Consent Forms, Anesthesia, Artificial Intelligence (AI)
- Trial name
- PEAR (NCT06949462)
- Testing
- PEAR
- Where
- 2 sites in Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Anesthesia
Minimum Effective Volume of Local Anesthetic Using Ultrasound for Brachial Plexus Block
The purpose of this study is to determine the minimum effective volume of local anesthetic for interscalene brachial plexus block using ultrasound guidance and nerve stimulator guidance.
- Trial name
- NCT01244932
- Testing
- bupivacaine 0.5%
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
CHD - Congenital Heart Disease
Bilateral Ultrasound Guided Superficial Parasternal Intercostal Plane Block Versus Erector Spinae Plane Block
Group (A): This group will receive fentanyl infusion at a dose of (0.5μg/kg/h) all through the whole operation plus ultrasound guided bilateral superficial parasternal intercostal Plane block which will be done by injecting…
- Trial name
- NCT06958120
- Testing
- superficial parasternal intercostal Plane block, Erecto spinea plane block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Obstetric
Analgesic Efficacy of Transvers Abdominis Plane Block and Transversalis Fascia Plane Block in Cesarean Section
This study was designed as a prospective, randomized observational clinical trial. A total of 90 adult women were included in the study performed elective cesarean section.
- Trial name
- NCT06386978
- Testing
- Transverse Facia Plane Block (TAP Block), Transversalis Facia Plane Block (TFP Block), Control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Airway Management, Induction of Anesthesia
The 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction
Exploring the 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction: The aim is to determine the optimal ventilation pressure for esophageal insufflation avoidance during…
- Trial name
- NCT07340255
- Testing
- Ultrasonic and inflation determination
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Affiliated Hospital of Jiaxing University
Forehead Rhytides, Forehead Wrinkles
Botulinum Toxin Type A Injection After Topical Anesthesia Versus Petrolatum Ointment
The purpose of this study is to determine whether there is a difference in clinical effect, duration of effect, level of discomfort and patient satisfaction in patients receiving topical anesthesia on one side of the forehead and…
- Trial name
- NCT03799484
- Testing
- Botulinum toxin type A, 2.5% lidocaine/2.5% prilocaine, petrolatum ointment
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Anesthesia, General Anesthesia
Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy
The objective of this trial is to determine whether an opioid-free general anesthetic (OFA) technique utilizing ketamine, dexmedetomidine, lidocaine, and gabapentin can help reduce postoperative respiratory depression in the…
- Conditions
- Anesthesia, General Anesthesia, Analgesics, Opioid, Postoperative Complications
- Trial name
- NCT02987985
- Testing
- Acetaminophen, gabapentin, Acetaminophen, Ketamine , Lidocaine , Dexmedetomidine
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Saskatchewan
Mastectomy; Lymphedema, Anesthesia, Local
Ultrasound-guided Paravertebral Block Versus Mid-point Transverse Process Pleura Block in Mastectomy Surgery
This study was performed to analyze the postoperative analgesic effects of the paravertebral block (PVB) and Mid-Point Transverse Process Pleura (MTP) block after a unilateral mastectomy surgery.
- Conditions
- Mastectomy; Lymphedema, Anesthesia, Local, Surgery
- Trial name
- NCT05332028
- Testing
- bupivacaine, 22 gauge 100 mm needle, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Anesthesia, General
Dose-Finding Trial With Sugammadex Administered at 3 and 15 Minutes After 1.0 and 1.2 mg/kg Rocuronium Bromide in Participants of ASA Class 1-3 (P05944; MK-8616-024)
The objective of this trial was to explore the dose-response relation of sugammadex (Org 25969; MK-8616) administered for the reversal of neuromuscular blockade (NMB) at 3 and 15 minutes following administration of 1.0 and 1.2…
- Trial name
- NCT00535743
- Testing
- Sugammadex, Esmeron®
- Volunteers
- 174 people
- Sponsor
- Merck Sharp & Dohme LLC
Depth of Anesthesia (DOA)
Effectiveness of the NeuroSENSE for Monitoring the Hypnotic Depth of Anesthesia
The objective of this clinical study is to investigate whether the NeuroSENSE is an adequate monitor of hypnotic depth-of-anesthesia (DOA).
- Trial name
- NCT02088671
- Testing
- Propofol induction followed by randomized doses of desflurane, Recording of EEG using NeuroSENSE, Data collection
- Where
- 2 sites in Canada
- Volunteers
- 76 people
- Sponsor
- NeuroWave Systems Inc.
Recovery Time From Isoflurane Anesthesia in Obese Patients
Acceleration of Recovery From General Anesthesia - Efficacy of Isocapnic Hyperpnoea in Obese Patients Undergoing Isoflurane Anesthesia
Faster recovery from anesthesia is important for obese patients because they are at high risk of respiratory complications following tracheal extubation.
- Trial name
- NCT00752492
- Testing
- Isocapnic Hyperpnoea
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University Health Network, Toronto
Anesthesia
Jet Injectors Versus Conventional Anesthetic Technique in Children
This clinical study was conducted to compare the needleless Comfort-in jet injector device and the conventional needle technique in terms of 1. Pain level during the administration of local anesthesia in children. 2.
- Trial name
- NCT06314984
- Testing
- Group I A (Conventional needle syringe), Group I B (Conventional needle syringe), Group II A (Comfort-in Jet Injector)
- Where
- Egypt
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Breast Cancer, Chronic Pain
Reducing Pain and Disability After Breast Cancer Surgery
The purpose of this study is to determine if the combination of thoracic paravertebral block and multimodal analgesia will decrease chronic pain and arm morbidity in patients undergoing breast cancer surgery with lymph node…
- Trial name
- RELIeF (NCT01089933)
- Testing
- Thoracic Paravertebral Block (TPVB), Local Anesthetic
- Where
- Canada
- Volunteers
- 129 people
- Sponsor
- Ottawa Hospital Research Institute
Anesthesia, Pediatric Cancer
the Efficacy and Safety of Sugammadex in Children 0-2 Years Old
Sugammadex is a selective antidote to muscle relaxants rocuronium bromide and vecuronium bromide. Sugammadex is a modified gamma-cyclodextrin, a compound that selectively binds rocuronium bromide and vecuronium bromide.
- Conditions
- Anesthesia, Pediatric Cancer, Pediatric Tumor, Pediatric Hepatoblastoma
- Trial name
- NCT03728543
- Testing
- Sugammadex
- Where
- Russia
- Volunteers
- 62 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Diabetic Foot, Regional Anesthesia
Efficacy of Continuous Sciatic Nerve Block in Diabetic Foot Patients
Patients who underwent surgery for diabetic foot were divided into three groups: sciatic nerve block (Group B), continuous nerve catheter (Group C) .
- Conditions
- Diabetic Foot, Regional Anesthesia, Catheter Blockage, Wound Heal
- Trial name
- NCT04212325
- Testing
- Group C (Continuous sciatic nerve block), Group S (sciatic nerve block)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gulhane School of Medicine
Plane Block, Regional Anaesthesia
Comparison of the Analgesic Efficacy of Subcostal TAP and M-TAPA Blocks in Laparoscopic Sleeve Gastrectomy Surgery
Objective The aim of this study is to compare the analgesic efficacy of bilateral subcostal transversus abdominis plane (TAP) and modified thoracoabdominal (M-TAPA) blocks in reducing intraoperative opioid consumption and…
- Conditions
- Plane Block, Regional Anaesthesia, Transversus Abdominis Plane (TAP) Block, Bariatric Surgery
- Trial name
- NCT06934772
- Testing
- M-TAPA, Subcostal TAP
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Haseki Training and Research Hospital
Post Operative Analgesia, Regional Anaesthesia
Comparison Between Paravertebral and Erector Spinal Block Efficacy in Robotic Thoracic Surgeries
The overall goal of this work is to find the preferred continues catheter- based thoracic block for patients who undergoing major ROBOTIC assisted thoracic surgery (Lobectomy, multiple segmental resection and thoracotomy).
- Conditions
- Post Operative Analgesia, Regional Anaesthesia, Pain After Surgery, Opioid Consumption
- Trial name
- TPVB vs ESP (NCT07782073)
- Testing
- Paravertebral Nerve Block, ESP block group
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Soroka University Medical Center
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