Clinical trials: Anesthesia Effectiveness
Catheter Related Bladder Discomfort
Dezocine for Prevention of Catheter-related Bladder Discomfort
This study evaluates the efficacy of dezocine in preventing the catheter-related bladder discomfort (CRBD) in a postanesthesia care unit (PACU).
- Trial name
- NCT03147066
- Testing
- Dezocine, Flurbiprofen Axetil
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Jian-jun Yang
Outpatient Rhinoplasty
Facial Block for Outpatient Rhinoplasty Analgesia
A bilateral facial block (infraorbital and infratrochlear) will be performed immediately after intubation in patients undergoing outpatient rhinoplasty with 2.5% levobupivacaine (intervention group) or saline as control.
- Trial name
- FABLORA (NCT01872728)
- Testing
- Bilateral facial block after general anesthesia before surgery
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Pain, Postoperative, Anaesthesia
Lumbar Erector Spinae Plane Block for Back Surgery
Title: A prospective randomized double blind trial of the efficacy of a bilateral lumbar erector spinae block on the 24 h morphine consumption after posterior lumbar interbody fusion surgery.
- Conditions
- Pain, Postoperative, Anaesthesia, Surgery, Nerve Block
- Trial name
- LUMBES (NCT03825198)
- Testing
- Erector spinae plane block, Levobupivacaine 0,25%, spine fusion
- Where
- 2 sites in Belgium
- Volunteers
- 80 people
- Sponsor
- Dr M. B. Breebaart
Mechanically Ventilated and Intubated Subjects
A Safety and Efficacy Study of Dexmedetomidine in ICU Patients Requiring Continuous Sedation
The purpose of this study is to evaluate the safety and efficacy of dexmedetomidine in ICU subjects who are initially intubated, mechanically ventilated and require sedation for beyond 24 hours.
- Trial name
- NCT00216190
- Testing
- Dexmedetomidine HCL Injection, Midazolam Injection
- Where
- 96 sites in United States, Argentina and 3 more
- Volunteers
- 420 people
- Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
Coronary Artery Bypass Surgery
Safety and Efficacy of Remimazolam in OPCAB Surgery
Remimazolam is a novel short-acting benzodiazepine drug that acts on the benzodiazepine binding site of gamma-aminobutryic acid (GABA) A receptor, is metabolized by esterase, and has a context-sensitive half-time of about 6-7…
- Trial name
- NCT05396690
- Testing
- Remimazolam Injection [Byfavo], Sevoflurane
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Ajou University School of Medicine
Knee Stiffness After Total Knee Arthroplasty
Flex Appeal: Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia
The purpose of this study is to determine if changing the type of anesthesia improves the outcomes of manipulation and pain control after the procedure.
- Trial name
- NCT07348614
- Testing
- Spinal Anesthesia, General Anesthesia, Propofol
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Duke University
Nefopam, Dexmeditomidine
Efficacy of Intravenous Nefopam, Dexmedetomidine, and Meperidine in Preventing Post-Spinal Anesthesia Shivering in Adult Patients Undergoing Lower Abdominal and Lower Limb Surgeries.
This prospective, randomized, controlled, double-blinded study is designed to evaluate the efficacy of nefopam compared to dexmedetomidine and meperidine for the prevention of postspinal anesthesia shivering while minimizing side…
- Conditions
- Nefopam, Dexmeditomidine, Meperidine, Post-spinal Anesthesia Shivering
- Trial name
- NCT06627816
- Testing
- Nefopam
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- Kasr El Aini Hospital
Drug Safety
Efficacy and Safety of Fospropofol in Adult Laparoscopic Surgery: A Clinical Trial
This protocol is a clinical study of fospropofol disodium for general anesthesia in adults undergoing laparoscope-assisted abdominal surgery.
- Trial name
- NCT06573489
- Testing
- Fospropofol, Propofol
- Where
- China
- Volunteers
- 373 people
- Sponsor
- Hui Xu
Major Depression
Study of Psilocybin Under Anesthesia Controlled by EEG
Major depressive disorder (MDD) affects millions of Americans and remains difficult to treat. Psilocybin, a psychedelic compound, has shown promise for reducing depression symptoms, but a key challenge in psychedelic research is…
- Trial name
- SPACE (NCT07479550)
- Testing
- Psilocybin (Usona Institute), Propofol
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Intraoperative Hypotension
PPI Guided Strategies for Prevention and Treatment of Intraoperative Hypotension
Intraoperative hypotension is closely related to the poor prognosis of surgery. The study is focused on the effectiveness of maintaining normal peripheral perfusion index (PPI) on time-weighted average of hypotension during…
- Trial name
- NCT05792696
- Testing
- PPI guided strategies, Empirical strategies
- Where
- China
- Volunteers
- 54 people
- Sponsor
- zhiqiang zhou
Airway Complication of Anaesthesia
Effectiveness and Safety of the Levitan Scope for Laryngoscopy and Tracheal Intubation With a Simulated Difficult Airway
A laryngoscope is a medical instrument that is used to get a view of the voice box and the space in between the vocal cords. A laryngoscope is used to place a breathing tube into the trachea (windpipe or airway) to protect the…
- Trial name
- NCT01491984
- Testing
- Laryngoscopy order: 1) MAC, 2) Levitan, Laryngoscopy order: 1) Levitan, 2) MAC
- Volunteers
- 105 people
- Sponsor
- IWK Health Centre
Anesthesia, Local
Efficacy of iv Fentanyl Citrate Administered Oral as a Pediatric Premedication
evaluate the efficacy of the intravenous formulation of fentanyl citrate administered orally as a sedative premedication, we will compare it with oral midazolam, as a gold standard premedication, in paediatric congenital cardiac…
- Trial name
- NCT04991298
- Testing
- Oral premedication
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- University of Alexandria
Comparative Evaluation of the Effect of pH Adjustment of the Solution of Articaine With Epinephrine on the Efficacy of Jet Anesthesia
Comparative Evaluation of the Effect of pH Adjustment of the Solution of Articaine With Epinephrine on the Efficacy of Jet Anesthesia
The purpose of this study is to evaluate the effect of pH adjustment of the solution of articaine 4% with epinephrine 1:100.00, on the efficacy of anesthesia with the usage of a local anesthesia device that is needle-free…
- Trial name
- NCT07318311
- Testing
- Local anesthesia with articaine 4% with 1:100.000 epinephrine by using Comfort-in device, Local anesthesia with articaine 4% with 1:100.000 epinephrine with the addition of sodium bicarbonate 8,4% by using Comfort-in device
- Where
- Greece
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Depressive Disorder
Effects of Ciprofol Anesthesia on Learning and Memory Function and Antidepressant Effects of ECT in Depressive Patients
In this clinical study, propofol was used as the positive control, and a randomized controlled trial design was used to observe the effects of ciprofol anesthesia on learning and memory function and antidepressant efficacy in…
- Trial name
- NCT05266560
- Testing
- ciprofol, Propofol
- Volunteers
- 390 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Anesthesia, Local
Analgesic Efficacy of Lidocaine Plus Bupivacaine Versus Bupivacaine Alone Caudally
Optimal analgesia following ambulatory surgery is an important matter for patient satisfaction and it reduces unnecessary hospital admissions.
- Trial name
- NCT03911648
- Testing
- 0.5 ml.kg-1 bupivacaine 0.25%, 0.5 ml.kg-1 bupivacaine 0.25% with the addition of 3 mg/kg lidocaine 1%
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Ayancık State Hospital
Hypothermia, Shivering
Efficacy of IV Fluid Warmer for the Prevention of Hypothermia
This study focuses on the importance of the maintenance of body temperature during the surgeries. This study involves the comparison of 2 groups, one receiving warm fluids while the other group receiving room temperature fluids…
- Trial name
- NCT07192224
- Testing
- Hypothermia, Hotline
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Adductor Canal Block
Effect of Combining Peri-hamstring Injection or Anterior Obturator Nerve Block on the Analgesic Efficacy of Adductor Canal Block for Arthroscopic Anterior Cruciate Ligament Reconstruction Under General Anesthesia
Pain after anterior cruciate ligament reconstruction with autologous hamstring graft can be attributed to both arthroscopic surgery and the graft donor site.
- Trial name
- NCT06398717
- Testing
- adductor canal block
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Pain, Shoulder Arthroscopy
SPENG Block Versus Suprascapular and Axillary Nerve Blocks for Pain After Shoulder Arthroscopy
This prospective, randomized, patient- and assessor-blinded, single-center non-inferiority trial will compare the analgesic efficacy of the Shoulder Posterior Pericapsular Nerve Group (SPENG) block with combined posterior…
- Trial name
- SPENG-RCT (NCT07762417)
- Testing
- Shoulder Posterior Pericapsular Nerve Group (SPENG) Block, Combined Posterior Suprascapular and Axillary Nerve Blocks
- Volunteers
- 60 people
- Sponsor
- Izmir City Hospital
Shoulder Injuries, Anesthesia
The Effects of Preloading Before Beach Chair Position
The main objective of this study is whether preloading before positioning would be effective for less hemodynamic instability. The study also analyzes that patients with preloading will decrease postoperative nausea and vomiting…
- Conditions
- Shoulder Injuries, Anesthesia, Hemodynamic Instability
- Trial name
- NCT04671537
- Testing
- Preloading with crystalloid fluid
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Neoplasm of Lung, Thoracic Surgery, Video-Assisted
Efficacy of Continous Regional Anesthesia Using m. Erector Spinae Catheter After VATS Procedures
Investigators will analyze the efficacy of continuous regional anesthesia through a catheter under erector spinae muscle in a prospective, randomized, double blind, placebo-controlled study.
- Trial name
- NCT04062045
- Testing
- Ropivacaine Hcl 0.2% Inj Vil 10Ml, Saline 0.9%
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- Surgery Bitenc
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