Clinical trials: Anesthesia Effectiveness
Paroxysmal Atrial Fibrillation
Conscious Sedation Versus General Anesthesia for Pulsed Field Ablation in Paroxysmal Atrial Fibrillation
This prospective, multicenter, randomized, controlled, noninferiority trial will compare local anesthesia with conscious sedation and general anesthesia in patients undergoing pulsed field ablation for paroxysmal atrial…
- Trial name
- PULSE-SED (NCT07877519)
- Testing
- Local Anesthesia With Conscious Sedation, General Anesthesia, VARIPULSE Pulsed Field Ablation System
- Where
- China
- Volunteers
- 390 people
- Sponsor
- China National Center for Cardiovascular Diseases
No Condition, Assessment of Healthy Volunteers
Usefulness of Intraosseous Anesthesia for Permanent Tooth Extraction Under GA in Pediatric Dental Treatment
The investigators are doing a study to see if a new way of giving local anesthesia during dental surgery can help children feel better after having a tooth removed under general anesthesia (when they are fully asleep).
- Trial name
- NCT07108439
- Testing
- Administration of intra-osseous local anesthesia before the extraction of a first permanent molar under general anesthesia
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Hospital, Ghent
Hypotensive Anesthesia
Comparison Between Two Drugs (Propofol and Nitroglycerin as a Hypotensive Agents During Endoscopic Sinus Surgery
Background and Objectives: FESS is a common minimally invasive surgery that requires a clear field to be performed well. Hypotensive anesthesia is one of the most common maneuvers performed to help in keeping the field clear.
- Trial name
- prop (NCT04220281)
- Testing
- Propofol, Nitroglycerin
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Regional Anesthesia Block
A Comparing Transversalis Fascia Plane Block and Quadratus Lumborum Block for Post-Cesarean Pain Management: Efficacy, Execution Time, and Practicality
Transversalis Fascia Plane Block (TFPB) and Quadratus Lumborum Block (QLB) provide superior analgesia to Transversus Abdominis Plane Block (TAPB) for post-cesarean pain management.
- Trial name
- NCT06874569
- Testing
- TAP Block:, TFP Block:, QLB:
- Where
- Egypt
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Aswan University
Cesarean Section, Dexamethasone
Intravenous Dexamethasone Effectiveness in Post Caesarean Section Analgesia
The management of postpartum pain is essential to ensure early rehabilitation for parturients. Intravenous dexamethasone has a potent analgesic action when used in the context of general anesthesia.
- Conditions
- Cesarean Section, Dexamethasone, Postoperative Pain, Spinal Anesthesia
- Trial name
- NCT05535036
- Testing
- Dexamethasone 4mg
- Where
- Tunisia
- Volunteers
- 84 people
- Sponsor
- Mongi Slim Hospital
Anesthesia, Spinal
Comparison of the Efficacy of 0.5% Bupivacaine, 0.5% Levobupivacaine, and 0.5% Hyperbaric Bupivacaine
About 15 million spinal anesthesia procedures are performed worldwide each year. In the daily practice of the anesthesiologist for intrathecal use there are various local anesthetics such as bupivacaine, hyperbaric solution of…
- Trial name
- BvsLBvsHB (NCT05184465)
- Testing
- spinal anesthesia
- Where
- Belarus
- Volunteers
- 111 people
- Sponsor
- Mogilev Regional Clinical Hospital
Type 2 Diabetes Mellitus, Coronary Disease
Anesthesia With Epinephrine in Diabetes Patients is Safe and Effective
The purpose of this study is to investigate the variation in blood glucose levels, hemodynamic effects and patient anxiety score during tooth extraction in type 2 diabetes mellitus with coronary disease patient under local…
- Trial name
- NCT02173067
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- University of Sao Paulo General Hospital
Pulpitis - Irreversible, Pulpitis - Reversible
Comparison of the Efficacy of Inferior Alveolar Nerve Block and Digital Anesthesia in Pulpectomy of Mandibular Permanent Molars in Children
This study aims to compare the effectiveness of inferior alveolar nerve block (IANB) and computer-controlled digital anesthesia in achieving adequate anesthesia in pediatric patients presenting with acute dental pain and…
- Trial name
- NCT07634900
- Testing
- Computer-Controlled Digital Anesthesia, Inferior Alveolar Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Inonu University
PDPH
Prophylactic Intrathecal Normal Saline for Prevention of Post Dural Puncture Headache in Women Undergoing Cesarean Section Under Spinal Anesthesia
The rates of cesarean section are increasing worldwide despite ten to fifteen percent of World Health Organization recommendation and from which 80-90% of cesarean sections are performed with spinal anesthesia.
- Trial name
- PDPH (NCT04393766)
- Testing
- Normal Saline
- Where
- Ethiopia
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Dilla University
Tonsillectomy, Ropivacaine
Analgesic Efficacy of Peritonsillar Ropivacaine Infiltration After Tonsillectomy in Children
Tonsillectomy is one of the most frequently performed surgical procedures in children and is commonly associated with significant postoperative pain.
- Conditions
- Tonsillectomy, Ropivacaine, Analgesia, Local Anesthesia
- Trial name
- NCT07825922
- Testing
- Peritonsillar infiltration with ropivacaine, Peritonsillar infiltration with normal saline, Normal Saline
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Hospital, Mahdia
Anesthesia, Sedation
Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration
This study is a pragmatic, randomized controlled pilot trial comparing remimazolam with propofol for endoscopic procedures, designed to assess the feasibility and clinical outcomes associated with implementing a pragmatic…
- Conditions
- Anesthesia, Sedation, Endoscopy
- Trial name
- SERENE (NCT07269808)
- Testing
- Remimazolam, Propofol
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Effectiveness of Anesthesia Using Electronic Syringe in Children in the Context of Endotopy Treatment
Effectiveness of Intraligament vs IANB Anesthesia in Children Using Electronic Syringe
This randomized clinical study aims to evaluate the efficacy and pain response of two local anesthesia techniques in pediatric dental treatment using an electronic syringe: ligament anesthesia and inferior alveolar nerve block…
- Trial name
- NCT07095946
- Testing
- Electronic Syringe Intraligament Technique, Electronic syringe IANB Technique
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Latakia University
Third Molars Extraction
Comparative Experimental Study Between Bupivacaine and Ropivacaine Regarding Efficacy in Third Molar Removal Surgery Under General Anesthesia
The goal of this clinical trial is to compare the efficacy of bupivacaine and ropivacaine in third molar removal surgery under general anesthesia in healthy volunteers.
- Trial name
- NCT07108465
- Testing
- Bupivacaine 0,5%, Ropivacaine 0,75%
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Henrique Tedesco
Nerve Block, Neuromuscular Blockade
Dosage of Mepivacaine in Ultrasound Axillary Block
The use of ultrasonography as an adjunct to regional anesthesia has significantly increased in recent years. Brachial plexus blockade by an axillary approach is amenable to the use of ultrasound guidance.
- Conditions
- Nerve Block, Neuromuscular Blockade, Anesthesia
- Trial name
- NCT01485653
- Testing
- Mepivacaine
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Autism Spectrum Disorder
Esketamine and Propofol for Children With Autism Spectrum Disorder Undergoing Colonoscopy
The purpose of this study is to examine the dose-response relationship of esketamine in combination with propofol for children with Autism Spectrum Disorder undering colonoscopy.
- Trial name
- NCT05951465
- Testing
- Esketamine, Propofol
- Where
- China
- Volunteers
- 46 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Healthy Volunteer
Study to Compare Active Tymbion Iontophoresis to Sham Tymbion Iontophoresis for Anesthesia of the Tympanic Membrane
A prospective, multicenter study to determine if active Tymbion iontophoresis is superior to sham Tymbion iontophoresis in providing anesthesia to the tympanic membrane (TM).
- Trial name
- ADEPT (NCT03119181)
- Testing
- Tymbion Lidocaine/epinephrine solution, Device: Iontophoresis System (IPS) with Drug: Tymbion lidocaine/epinephrine solution
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tusker Medical
ENT Surgery, Gynecological Surgery
Medico-economic Evaluation of Subcutaneous Automatic Resorbable Staples Device
A surgery made by an external incision requires to stitch the subcutaneous plans, usually performed using absorbable synthetic sutures hold on wire needle.
- Conditions
- ENT Surgery, Gynecological Surgery, Plastic Surgery
- Trial name
- S2CARA (NCT01546272)
- Testing
- Insorb resorbable staples, Monocryl resorbable wire
- Where
- 24 sites in France
- Volunteers
- 664 people
- Sponsor
- Nantes University Hospital
Anesthesia Insertion Complication, Airway Morbidity
The Effectiveness of Foley Airway Stylet Tool on Proseal LMA Insertion
Due to its soft cuff easily folded to impede ProSeal LMA insertion, many tools are developed. The aim of the study is to investigate the efficiency of ProSeal LMA insertion guided by a soft, direct optical Foley airway stylet…
- Trial name
- NCT02048657
- Testing
- Foley Airway Stylet Tool, introducer-tool
- Where
- Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Appendectomy, Pediatric
The Effectiveness of Dexmedetomidine as an Adjuvant for Bupivacaine Caudal Block in Pediatric Open Appendectomy Under General Anesthesia
This study aims to evaluate if adding dexmedetomidine to bupivacaine in a caudal block can provide longer and better quality pain relief for children after open appendectomy surgery.
- Trial name
- NCT07088900
- Testing
- caudal block using dexmedetomidine with bupivacaine, caudal block with bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Shoulder Pain, Artroscopic Surgery
Comparison of the Effectiveness of USG-Guided Interscalene Block Versus Combined Interscalen-Suprascapular Block for Arthroscopic Shoulder Surgery
This study aims to compare two commonly used regional anesthesia techniques for shoulder arthroscopy: the ultrasound-guided interscalene block and the combined interscalene-suprascapular nerve block.
- Conditions
- Shoulder Pain, Artroscopic Surgery, Postoperative Pain
- Trial name
- ISB vs SSB (NCT07445126)
- Testing
- Ultrasound-Guided Interscalene Block, Combined Ultrasound-Guided Interscalene and Suprascapular Nerve Blocks
- Volunteers
- 60 people
- Sponsor
- Asuman Ocaklar
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