Clinical trials: Anesthesia Effectiveness
Perfusion Index, Plethysmography
Evaluation of Caudal Block and Ilioinguinal-ilioohypogastric Nerve Block Efficacy with Perfusion Index (PI)
The study is a prospective, randomised, controlled double-blind clinical trial. The primary aim was to evaluate the efficacy of caudal block and ilioinguinal-iliohypogastric nerve block with PI and PVI in pediatric inguinal…
- Conditions
- Perfusion Index, Plethysmography, Anesthesia, Caudal, Nerve Block
- Trial name
- NCT06203743
- Testing
- caudal block group, ilioinguinal-iliohypogastric nerve block group
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Alopecia
Evaluating Vibrational Anesthesia in Scalp Platelet Rich Plasma (PRP)
This study is prospective, single-site, randomized split-scalp pilot and survey study of patients at the NYU Skin and Cancer Clinic or the Faculty Group Practice.
- Trial name
- NCT06497764
- Testing
- Vibrational Anesthesia (VA) Device, PRP Treatment
- Where
- United States
- Sponsor
- NYU Langone Health
Laparoscopic Surgery, Laparoscopic Appendectomy
Pre-incisional Infiltration With Ropivacaine Plus Diprospan for Relieving Postoperative Pain After Laparoscopic Surgery
Incisional infiltration is the simplest, safest, and most effective anesthesia method for preventing incision pain after laparoscopic surgery, but even using long-acting local anesthetics, the effectiveness of postoperative…
- Conditions
- Laparoscopic Surgery, Laparoscopic Appendectomy, Laparoscopic Cholecystectomy, Laparoscopic Hernia Repair Surgery
- Trial name
- NCT07626463
- Testing
- Pre-incisional infiltration with ropivacaine and diprospan, Pre-incisional infiltration with ropivacaine alone
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Tiantan Hospital
Post Operative Pain, Thoracic Cancer
Thoracic Paravertebral Block With Methylene Blue Visual Confirmation for Postoperative Pain After VATS Lobectomy
The goal of this study is to compare the efficacy in controlling postoperative pain of paravertebral block (PVB) with methylene blue visual confirmation and thoracic epidural anesthesia (TEA).
- Trial name
- NCT05812521
- Testing
- Paravertebral block with methylene blue, Thoracic Epidural Anesthesia
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Campania Luigi Vanvitelli
Abdominal Aorta Aneurysm, Abdominal Aorta Atheroma
Impact of Intra- and Postoperative Continuous Infusion of Lidocaine on Analgesia in Vascular Anaesthesia
The aim of the study is to test the effectiveness and safety of the use of lidocaine infusion in multimodal analgesic management.
- Conditions
- Abdominal Aorta Aneurysm, Abdominal Aorta Atheroma, Surgery, Pain, Postoperative
- Trial name
- NCT04691726
- Testing
- lidocaine 10mg/ml, Metamizole, Morphine
- Where
- Poland
- Volunteers
- 87 people
- Sponsor
- Łukasz Krzych
Computer-controlled Intraligamentary Anaesthesia, Inferior Alveolar Nerve Block
Comparison of the Computer Controlled and Conventional Local Anesthesia Techniques in Primary Molar Extraction in Children Aged 5 to 9 Years Old
The goal of this clinical trial is to assess pain perception, child stress level and compare the effectiveness between periodontal ligament anesthesia using Computer-controlled Local Anesthetic delivery system and the…
- Conditions
- Computer-controlled Intraligamentary Anaesthesia, Inferior Alveolar Nerve Block, Pain Perception, Anesthesia Effectiveness
- Trial name
- RCT (NCT06669039)
- Testing
- Computer-controlled Local Anesthetic delivery system, Inferior Alveolar Nerve Block
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Anxiety, Dental Pain
Comfort-in Needle-Free Injection System in Pediatric Dental Anesthesia
This randomized split-mouth clinical trial evaluated the efficacy of the Comfort-in needle-free injection system compared with conventional dental injection for local anesthesia during pulpotomy treatment in children.
- Conditions
- Dental Anxiety, Dental Pain, Pulpotomy, Local Anesthesia
- Trial name
- NCT07585812
- Testing
- Comfort-in Needle-Free Injection System, Conventional Dental Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Sugammadex, Extubation
Effectiveness on Smooth Extubation According to the Administration Time of Sugammadex
After surgery is completed under general anesthesia, extubation is performed after recovery from anesthesia, and during this process, bucking, coughing, and rapid and excessive hemodynamic fluctuations occur very often.
- Conditions
- Sugammadex, Extubation, Smooth Emergence
- Trial name
- NCT05751603
- Testing
- sugammadex
- Volunteers
- 66 people
- Sponsor
- Ajou University School of Medicine
Postoperative Shivering
Efficacy of Intrathecal Versus Intravenous Dexmedetomidine for Prevention of Post Spinal Anesthesia Shivering
compare the efficacy of intrathecal versus intravenous dexmedetomidine in attenuation and prevention of shivering in TURP under spinal anesthesia in a randomized controlled trial.
- Trial name
- NCT02965586
- Testing
- intrathecal
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Myofascial Pain - Dysfunction Syndrome of TMJ, Myofascial Trigger Point Pain
Is Masseteric Nerve Block Effective in Myofascial Pain
The aim of the present study was to compare the efficacy of three different treatment methods in the management of myofascial pain: masseteric nerve block (MN), trigger point injection(TrP) with local anesthetic (LA) and dry…
- Conditions
- Myofascial Pain - Dysfunction Syndrome of TMJ, Myofascial Trigger Point Pain, Local Anesthesia
- Trial name
- NCT04339673
- Testing
- masseteric nerve block, trigger point injection, dry needling
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Erzincan University
Anesthesia Intubation Complication
Muscle Relaxants on Efficacy of LMA Insertion
The use of laryngeal mask airway (LMA) is increasing in pediatric anesthesia because it provides lesser direct mechanical stimulation of the airway due to being placed above the larynx.
- Trial name
- LMA_MR (NCT03487003)
- Testing
- rocuronium, saline
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- Daegu Catholic University Medical Center
Acute Post Operative Pain, Hip Fracture
Pain Relief Comparison: Pericapsular Nerve Group Versus Quadratus Lumborum Block for Positioning in Femur Fracture Surgery
This study aims to compare the analgesic efficacy of Ultrasound Guided Pericapsular Nerve Group Block and Quadratus Lumborum Block for pain relief During patient Positioning for Spinal Anesthesia in proximal femur fracture…
- Conditions
- Acute Post Operative Pain, Hip Fracture, Regional Anaesthesia, Quadratus Lumborum Block
- Trial name
- NCT06917807
- Testing
- Pericapsuler nerve group block, Quadratus lumborum block
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Ain Shams University
Anesthesia, General
A Bridging Trial Comparing Sugammadex (Org 25969) at 1-2 Post-Tetanic Count (PTC) in Caucasian Participants. Part B (P05974)
The objective of the trial was to establish the dose-response relation of sugammadex given as a reversal agent of rocuronium or vecuronium at 1-2 Post-Tetanic Count (PTC) during sevoflurane anesthesia for Caucasian participants
- Trial name
- NCT00552929
- Testing
- Sugammadex
- Volunteers
- 102 people
- Sponsor
- Merck Sharp & Dohme LLC
Induction of Anesthesia
A Trial Evaluating the Efficacy and Safety of HSK3486 Injectable Emulsion for the Induction of General Anesthesia in Elective Surgery Subjects
This is a multi-center, randomized, double-blind, propofol-controlled phase III clinical trial. The primary objective is to compare the efficacy and safety between propofol and HSK3486 for the induction of general anesthesia in…
- Trial name
- NCT03808844
- Testing
- HSK3486, Propofol
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Sichuan Haisco Pharmaceutical Group Co., Ltd
Dental Caries
Effectiveness of the Intraligamentary Anesthesia and Inferior Alveolar Nerve Block on Pain During Dental Treatment
Objective: To compare the effectiveness and complications of intraligamentary anesthesia (ILA) with conventional inferior alveolar nerve block (IANB) during injection and dental treatment of mandibular posterior teeth.
- Trial name
- NCT04563351
- Testing
- local anaesthetic techniques
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Anxiety
Effectiveness of Mobile Applications During the Administration of Local Anesthesia in Pediatric Dentistry
To evaluate the mobile games' effect on patient acceptance of local anesthesia and decreasing dental pain and anxiety levels in pediatric patients.
- Trial name
- NCT04731181
- Testing
- mobile application (little lovely dentist).
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bronchoscopy, Anesthesia, Local
5 Versus 10 Sprays of Lignocaine for Pharyngeal Anaesthesia During Bronchoscopy
Flexible bronchoscopy is one of the most widely performed procedures for diagnosis of various bronchopulmonary diseases. Most patients tolerate the procedure well although cough is often reported as a distressing symptom.
- Trial name
- NCT03869528
- Testing
- 5 sprays of 10% lignocaine, 10 sprays of 10% lignocaine
- Where
- 2 sites in India
- Volunteers
- 300 people
- Sponsor
- All India Institute of Medical Sciences
Surgery, Anesthesia, Local
Bier's Block Versus Mini-bier's Block in Patients Undergoing Hand Surgery
By means of an observer-blinded, randomized controlled trial, the analgesic efficacy of an upper-arm Bier's block and a forearm mini-Bier's block will be investigated in patients undergoing hand surgery.
- Trial name
- NCT03761329
- Testing
- mini-Bier's block with lidocaine 0.5% 25ml, Conventional Bier's block with lidocaine 0.5% 40ml
- Where
- Belgium
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Knee Injuries and Disorders, Hip Injuries
Randomized, Controlled Trial Comparing the Effectiveness of Sedation-Epidural Anesthesia to Spinal Anesthesia in Outpatient Hip or Knee Arthroplasty.
To our knowledge, no study has compared the difference between these two NA techniques. Early postoperative adverse events like uncontrolled pain, orthostatic hypotension, urinary retention, and prolonged motor block are linked…
- Conditions
- Knee Injuries and Disorders, Hip Injuries, Anesthesia
- Trial name
- RCT SEA vs SA (NCT06332443)
- Testing
- Spinal anesthesia, Sedation epidural anesthesia
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Anesthesia, Local
Ultrasound-guided Lumbar Erector Spinae Plane Block in Patients Undergoing Lower Limb Vascular Surgery
the investigatots hypothesized that by injection a larger volume and higher concentration of local anesthetic in lumbar erector spinae plane block could result in successful anesthesia in patient undergoing lower limb vascular…
- Trial name
- NCT04644562
- Testing
- Erector Spinae plane block
- Where
- Egypt
- Volunteers
- 5 people
- Sponsor
- Beni-Suef University