Clinical trials: Anesthesia Effectiveness
Cataract
Comfort Operative Ocular Light Study
Digital 3D microscopes require less light and may be more comfortable for patients requiring cataract surgery under topical anesthesia compared to conventional microscopes.
- Trial name
- COOL (NCT05085314)
- Testing
- Ngenuity digital 3D microscope, Conventional microscope
- Where
- 2 sites in France
- Volunteers
- 134 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Complication of Anesthesia
Assessing Peripheral Nerve Block Scoring Systems for Intra-Operative and Post-Operative Analgesia
The purpose of this study is to determine if Peripheral Nerve Block scoring systems are effective in predicting the achievement of intra-operative anaesthesia and post-operative analgesia.
- Trial name
- NCT02041806
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- The Adelaide and Meath Hospital
Regional Anaesthesia
Comparison Between Ultrasound Guided Femoral 3 in 1 Block Versus Blind Fascia Iliaca Block Before Spinal Anaesthesia
This study aimed to evaluate the efficacy of ultrasound guided femoral 3 in 1 block versus the blind technique single shot fascia iliaca compartment block as an analgesia method in patients prior positioning for spinal…
- Trial name
- IKH (NCT03139617)
- Testing
- Fascia Iliaca Compartment Block (FICB), 3 in 1 femoral block (FNB)
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- Universiti Sains Malaysia
Symptomatic Irreversible Pulpitis
Effect of Preoperative Oral Tramadol on Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis
Aim: The purpose of this prospective, randomized, double-blind, controlled study was to compare the preoperative oral tramadol medication with ibuprofen and acetaminophen on the success of inferior alveolar nerve blocks (IANB) of…
- Trial name
- NCT04961268
- Testing
- TraMADol 50 Mg Oral Tablet, Tramadol 100 MG Oral Tablet, Ibuprofen 600Mg Tab
- Where
- Saudi Arabia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Alfarabi Colleges
Postoperative Pain
An International Trial to Evaluate the Efficacy and Safety of SABER®-Bupivacaine for Postoperative Pain Control in Patients Following Arthroscopic Shoulder Surgery
The objective is to identify the optimal dose of SABER-Bupivacaine for postoperative pain control in patients undergoing elective arthroscopic shoulder surgery on the basis of pharmacokinetics, efficacy and safety evaluations.
- Trial name
- NCT00993798
- Testing
- SABER-Bupivacaine Treatment 1a, Bupivacaine HCl Treatment 1c, SABER-Bupivacaine Treatment 2a
- Where
- 10 sites in Austria, Germany and 3 more
- Volunteers
- 107 people
- Sponsor
- Durect
Depressive Disorder
Effects of Ciprofol Anesthesia on Learning and Memory Function and Antidepressant Effects of ECT in Depressive Patients
In this clinical study, propofol was used as the positive control, and a randomized controlled trial design was used to observe the effects of ciprofol anesthesia on learning and memory function and antidepressant efficacy in…
- Trial name
- NCT05266560
- Testing
- ciprofol, Propofol
- Volunteers
- 390 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Ablation Techniques, RFA, Ablation Treatment
Efficacy and Safety of RFA vs MWA for Treatment of Large Benign Thyroid Nodules, RCT
We conduct a multi-institutional randomized control trial of RFA and MWA for the primary treatment of large, benign nodules. Adult patients >/=18 years of age who have a solitary thyroid nodule ≥20ml in volume who presents to 1)…
- Conditions
- Ablation Techniques, RFA, Ablation Treatment, Benign Thyroid Nodules, Local Anaesthesia
- Trial name
- NCT07804862
- Testing
- Radiofrequency ablation alone, Microwave ablation
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Hemodynamics, Transcatheter Aortic Valve Replacement
Efficacy and Safety of Ciprofol for General Anaesthesia in Patients Undergoing Transcatheter Aortic Valve Replacement
Aortic valve stenosis is the most common debilitating valvular heart lesion in old patients. Transcatheter aortic valve replacement (TAVR) is an emergent technique for high-risk patients with aortic stenosis.
- Conditions
- Hemodynamics, Transcatheter Aortic Valve Replacement, General Anesthesia, Post-induction Hypotension
- Trial name
- NCT05881291
- Testing
- ciprofol, propofol
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Opioid Use, Spine Fusion
Effectiveness of Combining Erector Spinea Block With Non Opioid Infusions as Opioid Free Anesthesia in Spine Surgeries.
opioid free anesthesia consists of combination of pharmacological and non pharmacological modalities that target different pathways of pain mechanism.
- Trial name
- NCT05850468
- Testing
- fentanyl infusion after general anesthesia and erector spinea block, lidocaine 2% and dextometometidine infusion after general anesthesia and erector spinea block
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Shivering, Post-Spinal Shivering
Efficacy of Intravenous Midazolam-Ketamine Combination Versus Placebo for Prevention of Post-Spinal Shivering in Elective Cesarean Section
Spinal anesthesia is the preferred anesthetic method for elective cesarean deliveries, but it frequently causes post-spinal shivering.
- Conditions
- Shivering, Post-Spinal Shivering, Hypothermia, Cesarean Section
- Trial name
- NCT07855523
- Testing
- Midazolam and Ketamine, 0.9% Sodium Chloride
- Volunteers
- 120 people
- Sponsor
- Assiut University
Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes
Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia
This study aims to evaluate topical application of Cocaine HCl 4% and 10% on safety and efficacy in local (topical) anesthesia for diagnostic procedures and surgeries on or through accessible mucous membranes of the nasal…
- Conditions
- Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes, of the Nasal Cavities
- Trial name
- NCT01746940
- Testing
- Cocaine HCl 4% Topical Solution, Cocaine HCl 10% Topical Solution
- Where
- 2 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Lannett Company, Inc.
Anterior Cervical Discectomy, Serratus Posterior Superior Intercostal Plane Block
Postoperative Analgesic Efficacy of SPSIPB in Anterior Cervical Discectomy
Anterior cervical discectomy is an operation performed for complaints of pain, numbness or loss of strength due to cervical disc disease.
- Conditions
- Anterior Cervical Discectomy, Serratus Posterior Superior Intercostal Plane Block, Postoperative Pain Management, Postoperative Pain
- Trial name
- NCT07238621
- Testing
- The group treated with intravenous analgesics, Serratus posterior superior intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cumhuriyet University
Breast Cancer, Postoperative Pain
Effectiveness of Ultrasound Guided Erector Spinae Plane Block Against Ultrasound Guided Serratus Anterior Block in Modified Radical Mastectomy
The aim of this study is to compare and evaluate the safety and analgesic efficacy of ultrasound guided ESP block and ultrasound guided serratus anterior plane block in patients undergoing modified radical mastectomy.
- Trial name
- NCT04606147
- Testing
- Serratus Anterior Plane Block, Erector spinae plane block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Esketamine, Loop Electrosurgical Excision
Anesthesia for Loop Electrosurgical Excision Procedure (LEEP).
The goal of this prospective, randomized controlled study study is to investigate the efficacy and safety of propofol combined with different doses of esketamine (ESK) for anesthesia during loop electrosurgical excision procedure…
- Conditions
- Esketamine, Loop Electrosurgical Excision, Propofol
- Trial name
- ESK，LEEP (NCT06574945)
- Testing
- intravenous injection of propofol only, intravenous injection of propofol +esketamine
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Qian Wu
Gastroscopy, Colonoscopy
A Clinical Trial to Evaluate the Efficacy and Safety of Methoxyethyl Etomidate Hydrochloride for Sedation/Anesthesia During Gastroscopy/Colonoscopy
A total of 270 subjects undergoing gastroscopy/colonoscopy were randomly assigned to the methoxetomidate hydrochloride group and the etomidate group according to the ratio of 2:1 with etomidate as the control group.Neither the…
- Trial name
- NCT06858852
- Testing
- ET-26HCl 0.8mg/kg group, Etomidate Injectable Product 0.3mg/kg group
- Where
- 6 sites in China
- Volunteers
- 270 people
- Sponsor
- Ahon Pharmaceutical Co., Ltd.
Anesthesia, Local, Intravitreal Injection
Cooling Anesthesia for Intravitreal Injection
The purpose of this clinical study is to evaluate the safety and efficacy of cooling anesthesia application to the eye as anesthesia for intravitreal injection using a novel cooling anesthesia device and determine the effects of…
- Conditions
- Anesthesia, Local, Intravitreal Injection, Macular Degeneration, Diabetic Macular Edema
- Trial name
- COOL-1 (NCT03732287)
- Testing
- Cooling Anesthesia
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Recens Medical, Inc.
Frozen Shoulder
MUA's Efficacy in Frozen Shoulder in Patients Which Already Received an Hidrodilatation
Hidrodilatation alone is as efective as Hidrodilatation + Movilization under anesthesia to treat the frozen shoulder
- Trial name
- NCT05001438
- Testing
- Hidro, MUA
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital Clinic of Barcelona
Urolithiasis
Analysis of the Effectiveness and Safety of RIRS Under Local Anesthesia and Its Influencing Factors
Retrograde intrarenal surgery (RIRS) is a well-established technique and is the first-line treatment option for upper urinary tract stones <2cm.
- Trial name
- NCT06737497
- Testing
- retrograde Intrarenal Surgery ( RIRS ) under local anesthesia
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Pain Management in Breast Surgery, Pain After Surgery
Comparison of the Analgesic Efficacy of Erector Spinae Plane Block in Breast-Conserving Surgery Versus Serratus Anterior Block Combined With Additional Pecto-Intercostal II Block
This prospective randomized study will compare the effects of Erector Spinae Plane Block (ESPB) and Serratus Anterior Plane Block combined with Pectoral Nerve Block Type II (SAPB + PECS II) on intraoperative analgesia and…
- Conditions
- Pain Management in Breast Surgery, Pain After Surgery, Regional Anaesthesia
- Trial name
- NCT07368413
- Testing
- SAPB + PECS II Technique, Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kayseri City Hospital
Cardiac Surgery, Postoperative Pain
Combine Serratus Anterior Plane Block Versus Erector Spinae Plane Block in Coronary Bypass Surgery
Even though Erector Spinae Plane (ESP) Block is shown to be efficient in cardiac surgery, the Combine Serratus Anterior Plane (CSAP) Block is still controversial if it has an efficient analgesic effect for sternotomy and drain…
- Conditions
- Cardiac Surgery, Postoperative Pain, Regional Anesthesia Morbidity
- Trial name
- NCT05308797
- Testing
- ESP block, CASP block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
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