Clinical trials: Anesthesia Management
Combat-Related Limb Injury, Nerve Block
Nerve Blocks or Combat Trauma: What Drives Peripheral Nerve Injury?
This study will examine nerve problems after combat-related injuries to the arms or legs. Some patients receive a peripheral nerve block, an injection of local anaesthetic near a nerve, to help control pain.
- Conditions
- Combat-Related Limb Injury, Nerve Block, Nerve Damage, Nerve Blocks
- Trial name
- NERVE-COMBAT (NCT07868133)
- Volunteers
- 1,000 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Pain
Comparison Between the Analgesic Effectiveness of Virtual Reality and Topical Anesthesia: A Clinical Study
A split-mouth, controlled trial aimed to clinically compare and evaluate the effectiveness of virtual reality versus topical anesthesia gel prior to administration of dental anesthesia injection in reducing the perceived pain and…
- Trial name
- NCT04919421
- Testing
- Dental injection and topical gel application, Dental injection and virtual reality device
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Cervical Incompetence in Pregnancy as Antepartum Condition
Hyperbaric Prilocaine Compared With Hyperbaric Bupivacaine in Cervical Cerclage?
Patients that have a "cervical stitch" (cervical cerclage) require an anaesthetic. The most common choice is a spinal block. This is an injection in the back that makes the lower half of the body become temporarily numb and weak.
- Trial name
- PRILOCC (NCT04394533)
- Testing
- Prilocaine (Hyperbaric 2%), Bupivacaine (Hyperbaric 0.5%)
- Where
- United Kingdom
- Volunteers
- 129 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Anesthesia Effectiveness
Pain Perception During Inferior Alveolar Nerve Block Administration in Children Using Vibraject and Dental Vibe Versus Conventional Syringe
This RCT study aims to establish evidence based decision comparing between Vibraject (MiltexInc LLC.,York,PA,USA).and Dental vibe(BING Innovations LLC,Crystal Lake,IL,USA versus Conventional Syringe on pain perception during…
- Trial name
- NCT07571278
- Testing
- Vibraject, Dental vibe, Conventional syringe
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative, Rebound Pain
Intravenous Dexamethasone With Single-Shot Versus Continuous Brachial Plexus Block for Rebound Pain After Shoulder Surgery
Shoulder surgery often causes severe pain after the operation. To control this pain, doctors commonly perform a nerve block (interscalene brachial plexus block), which numbs the shoulder area.
- Conditions
- Pain, Postoperative, Rebound Pain, Shoulder Injuries, Rotator Cuff Injuries
- Trial name
- NCT07699744
- Testing
- Dexamethasone (IV), Single-shot interscalene brachial plexus block, Continuous interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Steno-occlusive Disease
Effect of Dexmedetomidine on Hemodynamic Stability in Carotid Endarterectomy: Reduced Norepinephrine Use and Propofol Dosing Via Central Sympatholytic Action
1. Objective and Selection We refer to our research project as the "research project" in this information sheet. If you participate, you will be a participant.
- Trial name
- NCT07597109
- Testing
- dexmedetomidine to the standard treatment, Standard anaesthesia with propofol with co-administration of Dexmedetomidine and Propofol with Dexmedetomidine (bolus 0.4 mcg/kg over 10 minutes followed by an continuous infusion with 0.4 mcg/kg/h un
- Volunteers
- 44 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Local Anesthesia
Efficacy and Safety of Lambdalina (Lidocaine Cream) Versus Placebo as an Anesthetic for Laser Hair Removal
Double-blind, randomized, placebo-controlled trial to assess the efficacy of Lambdalina (lidocaine cream) in reducing pain associated with laser hair removal in women.
- Trial name
- NCT01360749
- Testing
- Lambdalina® (Lidocaine 4% cream)
- Where
- 2 sites in Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- ISDIN
Caries, Dental, Local Anesthesia
Effect of AI-Supported Child-Friendly Communication on Dental Anxiety in Pediatric Patients
This study compares the effects of traditional behavior management techniques and AI-assisted child-friendly communication on dental anxiety, physiological stress, and pain perception during local anesthesia in healthy children…
- Conditions
- Caries, Dental, Local Anesthesia, Inferior Alveolar Nerve Block, Dental Anxiety
- Trial name
- NCT07133919
- Testing
- AI-Assisted Child-Friendly Communication, Traditional Behavior Management Techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Video-assisted Thoracoscopic Surgery, Paravertebral Block
TPVB or SPSIPB in Pain Management After VATS
The goal of this clinical trial is to compare the analgesic efficacy of thoracal paravertebral block (TPVB) and serratus posterior superior intercostal plane block (SPSIPB) in patients undergoing video-assisted thoracoscopic…
- Conditions
- Video-assisted Thoracoscopic Surgery, Paravertebral Block, Serratus Posterior Superior Intercostal Plane Block, Regional Anesthesia Morbidity
- Trial name
- NCT06426706
- Testing
- Serratus Posterior Superior Intercostal Plane Block, Paravertebral Block
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Koç University
Anaesthesia, Anesthesia Depth Monitoring
Monitoring the Depth of Anesthesia and Nociception During the Induction of General Anesthesia in Pediatric Patients
Perioperative assessment of adequate depth of anesthesia and analgesia is currently a recommended part of routine anesthesia practice for all surgical procedures.
- Trial name
- ANIGAPP (NCT07245654)
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Brno University Hospital
Postoperative Pain After Thoracic Surgery, Coronary Artery Bypass Graft (CABG)
Comparison of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block in Postoperative Pain Management After Coronary Artery Bypass Grafting
Coronary Artery Bypass Grafting (CABG) is a common surgical procedure for ischemic heart disease, but it often leads to severe acute and chronic postoperative pain, which can delay recovery and reduce patient comfort.
- Trial name
- NCT07287761
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Ankara Education and Research Hospital
Intubation, Pediatric, Intubation; Difficult or Failed
Validation of the POGO Score for Classification of Videolaryngoscopy in Children - Post-hoc Analysis of the PeDiAC Study
It has been assumed that the percentage of glottic opening (POGO) score might enhance the classification of videolaryngoscopic tracheal intubation by offering a more objective rating of glottic exposure but studies in children…
- Conditions
- Intubation, Pediatric, Intubation; Difficult or Failed, Airway Management, Airway Complication of Anesthesia
- Trial name
- POGO-KIDS (NCT07115407)
- Where
- Germany
- Volunteers
- 809 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Peripheral Arterial Disease
Impact of Virtual Reality on Patient Pain During Lower Limb Revascularization Via Endovascular Surgery Under Local Anesthesia With Sedation
The prevalence of peripheral arterial disease (PAD) increases with age In addition to medical treatment, endovascular procedures can be performed, depending on the stage of the disease, to prevent complications and/or sequelae…
- Trial name
- REVDOU (NCT07181434)
- Testing
- The patient will be equipped with VR headsets
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Poitiers University Hospital
Spine Fusion, Locoregional Anaesthesia
PeriOPerative Spine Surgery COntrol Pain (POPSSCOP) Study: Intrathecal Morphine vs Erector Spinae Plane Block for Postoperative Pain Management in Spinal Fusion
This is a prospective observational study conducted at the trauma center of Città della Salute e della Scienza of Turin. The aim of the study is to compare two local regional anesthesia techniques in multimodal analgesia for…
- Conditions
- Spine Fusion, Locoregional Anaesthesia, Intrathecal Anesthesia, Erector Spina Plan Block
- Trial name
- POPSSCOP (NCT07245524)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Dental Anesthesia, Nasal Surgical Procedures
Hemodynamic and Pharmacokinetic Analysis of Oxymetazoline Absorption
Oxymetazoline is an α-adrenergic agonist that is commonly used as a topical sympathomimetic agent in over-the-counter decongestant sprays.
- Conditions
- Dental Anesthesia, Nasal Surgical Procedures, Intranasal Drug Administration
- Trial name
- NCT02062996
- Testing
- Oxymetazoline
- Where
- United States
- Sponsor
- Richard Cartabuke
Gallbladder Stones, Gallbladder Polyps
A Study on the Efficacy and Safety of Anrikefon for Postoperative Pain Relief Following Laparoscopic Cholecystectomy
This study is a multicenter, randomized, 1:1 parallel-group controlled clinical trial designed to evaluate the efficacy and safety of Anrikefon for postoperative analgesia in patients undergoing elective laparoscopic…
- Trial name
- NCT07741188
- Testing
- Anrikefon, Dezocine
- Where
- 2 sites in China
- Volunteers
- 144 people
- Sponsor
- Affiliated Hospital of Guangdong Medical University
Regional Anesthesia Techniques in Shoulder Surgery
Effectiveness of Field Block Compared With Interscalene Block in Shoulder Surgery
This study will compare two different types of anesthesia used for shoulder surgery. The first method, called an interscalene block, is commonly performed by anesthesiologists and is effective for pain control but may cause side…
- Trial name
- BLOCK-SHOULDER (NCT07173894)
- Testing
- Shoulder Field Block by Orthopedic Surgeon, Interscalene brachial plexus block and superficial cervical plexus block
- Where
- Israel
- Volunteers
- 64 people
- Sponsor
- Rabin Medical Center
Anesthesia
Use of Stable Airway Management Device in Monitored Anesthesia Care
The aim of this study is to determine if the Stable Airway Management device (SAM) is safe in maintaining the airway in a stable, non-obstructing position during anesthetic cases requiring monitored anesthesia care (MAC).
- Trial name
- NCT05087979
- Testing
- Stable airway management (SAM) device
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Virginia Commonwealth University
General Anesthesia With Endotracheal Intubation in Surgery
Cohort 2 Efficacy of Nasopharyngeal Ventilation With Endotracheal Tube for Surgery
Failed mask ventilation poses an increased risk of de-oxygenation to the patient undergoing general anesthesia. Nasopharyngeal ventilation may be a valid alternative for mask ventilation allowing for better oxygenation during the…
- Trial name
- MASK (NCT02018146)
- Testing
- Mask then nasopharyngeal, Nasopharyngeal then mask
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Louisville
Failed or Difficult Intubation
Three-dimensional Craniofacial Phenotyping of Patients With Difficult Airway
The purpose of this study is to identify differences in craniofacial morphology and tongue size between patients who have a history of difficult airway management and a control group of patients who had an uneventful airway…
- Trial name
- NCT01630694
- Testing
- 3D Laser Scanning of the Head, Measurements and Digital Photo's of the head, neck and Mouth, Ultrasound Exam of the Tongue
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Rochester