Clinical trials: Anesthesia Management
Carotid Artery Stenosis, Acute Ischemic Stroke
Acute Stroke of CArotid Artery Bifurcation Origin Treated With Use oF the MicronEt-covered CGUARD (SAFEGUARD-STROKE)
Prospective, single-center, clinical registry of patients with acute stroke of carotid artery bifurcation origin undergoing endovascular treatment using the Micronet-covered CGUARD Stent to seal the culprit lesion under proximal…
- Trial name
- NCT05195658
- Testing
- Thrombectomy and Stenting under neuroprotection
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- John Paul II Hospital, Krakow
Cardiovascular Surgery, Bispectral Index
BIS Monitoring in Relation to Muscle Relaxant Administration
The purpose of this study is to determine the overall optimal timing of when the Bispectral Index (BIS) monitor should be started: before or after the muscle relaxant is given.
- Conditions
- Cardiovascular Surgery, Bispectral Index, Anesthesia
- Trial name
- NCT05440058
- Testing
- Bispectral Index (BIS) monitoring system
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Mayo Clinic
Airway Management, Tracheal Extubation
Interest of Tracheal Extubation in Positive Pressure on Postoperative Oxygenation in Adult Digestive Surgery
Evaluation of a postoperative tracheal extubation protocol under positive pressure in accordance with international recommendations.
- Conditions
- Airway Management, Tracheal Extubation, Postoperative Respiratory Complications, Postoperative Hypoxemia
- Trial name
- ExPress (NCT04381949)
- Testing
- positive pressure extubation
- Where
- France
- Volunteers
- 208 people
- Sponsor
- University Hospital, Rouen
Pain Management
Opioid-free Anesthesia as an Alternative to General Anesthesia in Patients Undergoing Laparoscopic Peripheral Pancreatic Resection
Opioid-free anesthesia is not associated with greater pain than opioid anesthesia and is associated with reduced postoperative pain.
- Trial name
- OFAPP (NCT07378189)
- Testing
- Opioid Free Anesthesia (OFA), Balanced anesthesia with opioids
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Jagiellonian University
Distal Radius Fracture
"Supracondylar Radial Nerve Block Guided by Ultrasound Versus Hematoma Block for Analgesic Management in Closed Reduction of Distal Radius Fractures"
Non-surgical treatment with closed reduction and immobilization using a splint or cast is the preferred approach for stable distal radius fractures, particularly in elderly patients.
- Trial name
- NCT06857110
- Testing
- ultrasound-guided supracondylar block of the radial nerve, hematoma block, 5 mg of intramuscular diclofenac
- Where
- Colombia
- Volunteers
- 50 people
- Sponsor
- Hospital Universitario San Ignacio
Hip Pain Chronic, Anesthesia
Hip Arthroscopy Pain Control Randomized Control Trial (RCT)
Femoroacetabular impingement is a pathologic process within the hip joint that results from a mechanical discord between the femoral head and neck and the acetabulum that results in chronic hip pain, hip labral tears and early…
- Conditions
- Hip Pain Chronic, Anesthesia, Bupivacaine
- Trial name
- NCT02947178
- Testing
- Fascial iliac regional soft tissue infiltration blockade, Pain Score Survey, Pill Count
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Postoperative Pain Management, Postoperative Nausea and Vomiting
LAPOFAR Trial: Opioid-Free vs. Remifentanil Anesthesia in Laparoscopic Cholecystectomy
This study was a single-center, prospective, randomized clinical trial designed to compare the effects of opioid-free anesthesia (OFA) with standard opioid-based anesthesia during elective laparoscopic cholecystectomy.
- Conditions
- Postoperative Pain Management, Postoperative Nausea and Vomiting, Laparoscopic Cholecystectomy, Opioid-free Anesthesia
- Trial name
- LAPOFAR (NCT07307625)
- Testing
- Lidocaine + Dexmedetomidine, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Anesthesia
Safety and Pharmacokinetics of Kovacaine Nasal Spray in Pediatric Subjects
The purpose of this study is to determine the pharmacokinetics and safety of a nasal spray containing the anesthetic drug Tetracaine in combination with Oxymetazoline in healthy pediatric subjects.
- Trial name
- NCT01952990
- Testing
- Tetracaine HCl 3% and Oxymetazoline HCl 0.05%
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- St. Renatus, LLC
Anxiety, Preoperative
Management of Preoperative Anxiety in Children: Could a Lollipop Be the Solution?
The aim of the study is to evaluate the effectiveness of distraction using a lollipop versus premedication with intranasal midazolam to manage preoperative anxiety in pediatric anesthesia.
- Trial name
- NCT06670846
- Testing
- Lollipop, distraction using intranasal Midazolam
- Where
- Tunisia
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Tunis University
Postamputation Pain, Lower Limb Amputation
Acute Post-Amputation Pain Management After Combat-Related Lower Limb Injury
Acute post-amputation pain remains a significant clinical challenge in patients with combat-related lower limb injuries and may negatively affect early rehabilitation, mobility, and opioid consumption.
- Conditions
- Postamputation Pain, Lower Limb Amputation, Combat Trauma
- Trial name
- APAPMACRLLI (NCT07863921)
- Testing
- Continuous Peripheral Nerve Blocks, Peripheral Nerve Cryoablation, Standard multimodal analgesia
- Where
- Ukraine
- Volunteers
- 36 people
- Sponsor
- Kharkiv National Medical University
Preeclampsia, Lung Edema
Artificial Intelligence in Lung Ultrasound for Preeclampsia
A total of eight quadrants of standard lung US examination was performed to all pregnant women with preeclampsia within the scope of the study by the same anesthesiologist, dividing each hemithorax into four regions through the…
- Trial name
- NCT05487014
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Gazi University
Intensive Care Unit
Regional Anaesthesia in Intensive Care Unit
Pain is a major problem in Intensive Care Unit (ICU). Adequate pain management not only means decreasing the pain intensity, but also improving the functionality and allowing the early mobilization that is a prerequisite for…
- Trial name
- Week'ALR (NCT05131633)
- Where
- 19 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Blood Transfusion, Hip Replacement
Blood Transfusion Applications in Hip Replacements
Introduction and Aim In the intraoperative or postoperative period of hip replacement surgeries, approximately 46% of patients receive erythrocyte transfusion.
- Conditions
- Blood Transfusion, Hip Replacement, Anesthesia Management
- Trial name
- NCT05627544
- Testing
- Anesthesia management/Hip replacement surgery, Demographic data, Chronic diseases
- Where
- Turkey (Türkiye)
- Volunteers
- 560 people
- Sponsor
- Baskent University
Ventricular Tachycardia
Anesthetic Management in Patients Undergoing Epicardial Ablation
The study is a retrospective study and is descriptive in nature. In this study, the investigators aimed to emphasize the importance of anesthesia management by cardiac risk assessment of patients undergoing epicardial ablation…
- Trial name
- NCT06538987
- Testing
- percutaneous epicardial ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Airway Management
Patient Positioning and Airway Management During ERCP
The aim of this study is to determine the effect of airway management (a set of medical procedures performed to prevent airway blockage and thus ensure an open path between a patient's lungs and the atmosphere) during endoscopic…
- Trial name
- NCT02850887
- Testing
- general endotracheal anesthesia, deep sedation without endotracheal intubation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Washington University School of Medicine
the Impact of Modern Anesthesia Techniques Applied in Pediatric Dentistry on Physiological Parameters
Comparison of the Effects of Intraosseous Anesthesia Performed With the SleeperOne5 Computer-Controlled Device and Conventional Mandibular Nerve Block on Behavior and Pain Control During Anesthesia Administration in Children Aged 5-9
The injection stage is the most intense cause of anxiety during dental treatment in the pediatric patient group. It is aimed to keep the pain sensation at a minimum during this process.
- Trial name
- NCT07198997
- Testing
- digital anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Saglik Bilimleri Universitesi
Analgesia, Arthropathy of Knee
Comparison of Two Different Regional Analgesia Techniques for Patients Undergoing Total Knee Arthroplasty
The objective of this clinical trial is to compare two regional analgesia techniques in patients undergoing total knee arthroplasty: IPACK (Infiltration of local anesthetic between the Popliteal Artery and Capsule of the Knee) vs…
- Conditions
- Analgesia, Arthropathy of Knee, Postoperative Pain
- Trial name
- PIPACK (NCT06179641)
- Testing
- Selective tibial nerve block, IPACK block
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Postoperative Pain, Psychological Factors
Psychosocial Factors and Postoperative Pain in Aesthetic Breast Surgery
This study investigates the relationship between psychosocial factors, particularly self-esteem and personality traits, and postoperative pain in patients undergoing aesthetic breast surgery.
- Conditions
- Postoperative Pain, Psychological Factors, Breast Surgery, Aesthetic Surgery
- Trial name
- NCT06707818
- Testing
- Preoperative Interventions, Intraoperative Interventions, Postoperative Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- V.K.V. American Hospital, Istanbul
Pain, Anxiety
Music and Local Anesthesia During Dermatologic Procedures
The goal of the study is to determine the effect of classical music on participants pain and anxiety associated with lidocaine administration during routine standard of care dermatologic procedures.
- Trial name
- NCT04317170
- Testing
- Music
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Anaesthesia, Anxiety
Impact of AR Glasses on Children's Behavior During Dental Nerve Blocks
The aim of this study is to evaluate the effectiveness of augmented reality glasses in managing pain, anxiety, and behavior in pediatric patients during inferior alveolar nerve block Group A (Control group): inferior alveolar…
- Trial name
- NCT06724341
- Testing
- Distraction
- Where
- Syria
- Volunteers
- 108 people
- Sponsor
- Damascus University