Clinical trials: Anesthesia Management
Infant Apnea, Surgical Procedure, Unspecified
Apneic Oxygénation by Nasal Canula During Infants Airway Management Study
This is a randomized clinical trial investigating the utility of apneic oxygenation via high flow nasal cannulae during airway management for infants general anaesthesia.
- Conditions
- Infant Apnea, Surgical Procedure, Unspecified, Airway Management
- Trial name
- Oxyeno (NCT03967769)
- Testing
- High Flow nasal Cannula
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Clermont-Ferrand
Airway Aspiration, Airway Complication of Anesthesia
Is Endotracheal Tube Use Mandatory in Patients Undergoing Nasal Septum Surgery?
The efficacy of supraglottic airway device use in many surgeries has been shown. Due to concerns such as tracheal blood leakage and vocal cord contamination in nasal septum surgery, there are doubts about the use of laryngeal…
- Trial name
- LMA (NCT03903679)
- Testing
- Laryngeal mask airway, Endotracheal tube
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Inonu University
Anesthesia
Safety and Pharmacokinetics of Kovacaine Nasal Spray (24 Hour Blood Collection)
The purpose of this study is to determine the pharmacokinetics/pharmacodynamics and safety of a nasal spray containing the anesthetic drug tetracaine in combination with oxymetazoline with blood draws over 24 hours.
- Trial name
- NCT01807624
- Testing
- Tetracaine HCl 3% and Oxymetazoline HCl 0.05%
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- St. Renatus, LLC
General Anesthesia, Airway Management
I-gel Plus Supraglottic Airway Device for Surgical Procedures in Prone Position
I-gel Plus is a novel supraglottic airway device that has been evaluated in various studies with high success and low complication rates.
- Conditions
- General Anesthesia, Airway Management, Supraglottic Airway
- Trial name
- NCT06602817
- Testing
- Exposure: prone position, Exposure: Supine position
- Where
- Germany
- Volunteers
- 28 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Lung Resection Surgery, Anesthesia General
Effect of Oxygen Administration in the Non-dependent Lung on Postoperative Complications After Lung Surgery
The purpose of this study is to analyze the effectiveness of apneic oxygenation and CPAP applied to the non-dependent lung during pulmonary resection surgery in reducing inflammatory response, ischemia-reperfusion injury, and…
- Trial name
- NCT07461779
- Testing
- Medicinal gas - oxygen (Nippon Gases 200 bar), CPAP, Oxygen therapy according to standard clinical practice
- Where
- Spain
- Volunteers
- 177 people
- Sponsor
- Francisco Andres de la Gala
Hypotension on Induction
PoCUS Guided Fluids to Prevent Post-induction Hypotension
Hypotension is a common side-effect of general anesthesia induction, and is related to adverse outcomes, including a significantly increased risk of one-year mortality.
- Trial name
- HIPO (NCT05424510)
- Testing
- Ringer's Lactate, IV line
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Mount Sinai Hospital, Canada
Mastectomy, Rhomboid Intercostal Block
Effects of Rhomboid Intercostal Block on Postoperative Pain Management and Chronic Pain Incidence in Mastectomies
The goal of this clinical trial is to evaluate the effects of the Rhomboid Intercostal Block (RIB) on postoperative chronic pain prevalence at 3 months (primary outcome) and on acute pain control, total opioid consumption, and…
- Conditions
- Mastectomy, Rhomboid Intercostal Block, Chronic Pain Following Surgical Procedure for Cancer
- Trial name
- NCT06756048
- Testing
- Rhomboid Intercostal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Koç University
Regional Anesthesia Techniques in Shoulder Surgery
Effectiveness of Field Block Compared With Interscalene Block in Shoulder Surgery
This study will compare two different types of anesthesia used for shoulder surgery. The first method, called an interscalene block, is commonly performed by anesthesiologists and is effective for pain control but may cause side…
- Trial name
- BLOCK-SHOULDER (NCT07173894)
- Testing
- Shoulder Field Block by Orthopedic Surgeon, Interscalene brachial plexus block and superficial cervical plexus block
- Where
- Israel
- Volunteers
- 64 people
- Sponsor
- Rabin Medical Center
Pain, Postoperative
Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia
The purpose of this study is to investigate the effectiveness of various oral analgesic regimens in minimizing post-operative pain and discomfort in young children following dental rehabilitation under general anesthesia (DRGA).
- Trial name
- NCT06757075
- Testing
- Ibuprofen, Acetominophen
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Boston University
Surgery
Fluid Management After Surgery in the Post-Anesthetic Care Unit (PACU)
The objective of the present study is to describe the current practice of postoperative fluid management in the Post Anesthesia Care Unit (PACU) of the Shaare Zedek Medical Center, Jerusalem, Israel.
- Trial name
- NCT00947401
- Where
- Israel
- Volunteers
- 1,000 people
- Sponsor
- Shaare Zedek Medical Center
Cesarean Section
Perineuraxial Anesthesia Fluid Management and Infant Neurobehaviors
Early change in neurobehavior is strongly associated with the intelligence development of children. Previous studies reported that cesarean section itself could influence the later development of children.
- Trial name
- PAFUMIN (NCT00987701)
- Testing
- Ringer's Lactate, Six percent hydroxyethyl starch
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Nanjing Medical University
Tooth Avulsion
Efficiency of a Guiding Device for Inferior Alveolar Nerve Block, EZ-Block®, Compared to a Conventional Freehand Administration.
The success rates reported in the literature for the various truncal anesthesia techniques are extremely variable and have shown a lack of reproducibility of the techniques.
- Trial name
- NCT05214664
- Testing
- Anesthesia
- Where
- 5 sites in France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Elsan
Postoperative Residual Curarization, Neuromuscular Block Prolonged
Postoperative Residual Neuromuscular Block and Passive Smoke Exposure in Pediatric Dental Patients
Postoperative residual neuromuscular block (PRNB) may persist despite apparent clinical recovery from neuromuscular blockade and may increase the risk of postoperative respiratory complications.
- Trial name
- NCT07831434
- Testing
- Passive Smoke Exposure
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Istanbul University - Cerrahpasa
Thoracotomy Surgery, Anesthesia
Ultrasound-guided PVB
Thoracotomy, is a surgical procedure performed routinely in connection with pulmonary surgery. Pain induced by thoracotomy is considered as the most severe post-operative pain.
- Conditions
- Thoracotomy Surgery, Anesthesia, Ultrasound-guided PVB, Post-operative Pain
- Trial name
- BPV échoguidé (NCT01842698)
- Testing
- ultrasoundguided paravertebral catheter
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Jean Perrin
Hypotension, Spinal Anesthesia
10 Vs.15 mcg Norepinephrine Bolus in Severe Maternal Hypotension During Cesarean Delivery
Data regarding the optimum dose of norepinephrine for management of severe maternal hypotension is lacking. A previous report showed that the use of 10-mcg norepinephrine bolus was not superior to the 5-mcg bolus in the…
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Section
- Trial name
- NCT06512415
- Testing
- 10 mcg Norepinephrine, 15 mcg Norepinephrine
- Where
- Egypt
- Volunteers
- 184 people
- Sponsor
- Cairo University
Analgesia, Pain Management
Clinical Impact of IPACK Block Addition to Suprainguinal Fascia Iliaca Block
In our clinic, routine suprainguinal fascia iliaca block (SIFIB) has been administered for postoperative analgesia in patients undergoing knee arthroplasty.
- Conditions
- Analgesia, Pain Management, Acute Pain
- Trial name
- NCT06054945
- Testing
- SIFIB (suprainguinal fascia iliaca block), IPACK (Interspace between the popliteal artery and capsule of the posterior knee ), Patient controlled anagesia device
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Samsun University
Emergency Surgery
Preoperative Rapid Pou Ultrasound Assessment in Critically Ill Patients Undergoing Emergency Surgery
With the development of society, the number of emergency critical operations is increasing year by year. Traditionally, the patient's systemic and circulatory status is indirectly assessed by testing and blood pressure heart…
- Trial name
- NCT04111783
- Testing
- POU protocol ultrasound
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shenzhen People's Hospital
Pain, Postoperative, Anesthesia, Local
Postoperative Analgesia in Laparoscopic Abdominal Surgery After Exparel Via TAP or Local Infiltration
This study evaluates differences in how administering liposomal bupivacaine via two different methods affects postoperative pain control in laparoscopic abdominal surgery patients.
- Conditions
- Pain, Postoperative, Anesthesia, Local, Anesthesia; Functional, Anesthesia
- Trial name
- NCT03927326
- Testing
- Exparel 266 MG Per 20 ML Injection
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Washington
Anesthesia Effectiveness
Pain Perception During Inferior Alveolar Nerve Block Administration in Children Using Vibraject and Dental Vibe Versus Conventional Syringe
This RCT study aims to establish evidence based decision comparing between Vibraject (MiltexInc LLC.,York,PA,USA).and Dental vibe(BING Innovations LLC,Crystal Lake,IL,USA versus Conventional Syringe on pain perception during…
- Trial name
- NCT07571278
- Testing
- Vibraject, Dental vibe, Conventional syringe
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mask Ventilation, General Anesthesia
Prediction of Difficult Mask Ventilation Using 3D-Facescan and Machine Learning
The aim of this study is to prove feasibility and assess the diagnostic performance of a machine learning algorithm that relies on data from 3D-face scans with predefined motion-sequences and scenes (MASCAN algorithm), together…
- Trial name
- MASCAN (NCT05411406)
- Where
- Germany
- Volunteers
- 423 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf