Clinical trials: Anesthesia Management
Hypothermia
Intraoperative Warming Comparison of Devices
Hypothermia is a common and serious complication during anesthesia and surgery. Anesthetic-induced hypothermia results from the inhibition of thermoregulatory control and exposure to cold operating room environment.
- Trial name
- NCT00650260
- Testing
- Dynatherm Medical vitalHEAT Temperature Management System vH2, Bair Hugger™ (Arizant Healthcare, Eden Prairie, MN)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Pain After Total Knee Arthroplasty, Pain Management
Combined Distal Femoral Nerve Block for Pain Control After Knee Replacement
The goal of this clinical trial is to see whether a combined distal femoral nerve block improves pain relief after total knee replacement in adults having planned surgery.
- Trial name
- FEM-COMB (NCT07629388)
- Testing
- Combined distal femoral nerve block, Saphenous nerve block alone, Standard perioperative care in both groups
- Where
- France
- Volunteers
- 240 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Acute Pain
ANI Versus Standard Care in Surgical Patients Receiving Balanced Sevoflurane-Fentanyl Anesthesia
This study aims to be a randomized, controlled study of ANI-guided opioid administration versus standard clinical practice in surgical patients undergoing general anesthesia with balanced sevoflurane-fentanyl.
- Trial name
- NCT03684590
- Testing
- ANI-guided opioid administration, Standard opioid administration
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pain, Postoperative, Osteoarthritis, Knee
Comparing Local Anesthetic Injections to Nerve Blocks for Pain Control After Total Knee Replacement
Why are we doing this study? People who have knee replacement surgery often feel pain afterward. Doctors use different methods to control this pain.
- Conditions
- Pain, Postoperative, Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Trial name
- LIA-PNB-TKA (NCT07744503)
- Testing
- Continuous Femoral and Sciatic Nerve Block (Ropivacaine), Local Infiltration Analgesia (Ropivacaine, Ketorolac, Epinephrine)
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Christopher Male
Obese Patients, Bariatric Surgical Pain
Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy
Regional anesthesia is a technique in which a local anesthetic is injected near a nerve or spinal cord to block sensation, motor stimulation, and pain.
- Conditions
- Obese Patients, Bariatric Surgical Pain, Bariatric Surgery (Sleeve Gastrectomy ), Non-Opioid Pain Management
- Trial name
- NCT07084753
- Testing
- Levobupivacaine, Dexamethasone contained in the solution for thoracic paravertebral block, Adrenaline
- Where
- Croatia
- Volunteers
- 36 people
- Sponsor
- IVO JURISIC
Open Heart Surgery
Closed Loop Isoflurane Administration With Bispectral Index in Open Heart Surgery
With the advancement in microprocessor technology and better understanding of pharmacodynamics and pharmacokinetics of anaesthetic agents, computer facilitated closed loop control of anaesthesia using propofol has been shown to…
- Trial name
- NCT01069562
- Testing
- Conventional control, Closed loop control
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Evaluation, Outpatient Surgery
Out-patient Discharge Management After General Intravenous Anesthesia
The lower limit of time for postoperative observation and discharge criteria for diagnostic or operational tests program in outpatient under general intervenous anesthesia/sedation
- Trial name
- NCT05609383
- Testing
- assessment
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cesarean Section
Perineuraxial Anesthesia Fluid Management and Infant Neurobehaviors
Early change in neurobehavior is strongly associated with the intelligence development of children. Previous studies reported that cesarean section itself could influence the later development of children.
- Trial name
- PAFUMIN (NCT00987701)
- Testing
- Ringer's Lactate, Six percent hydroxyethyl starch
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Nanjing Medical University
Pain Management, Regional Anesthesia
Revision of Deep Brain Stimulator in Patients With Parkinson's Disease
Parkinson's disease is a chronic and progressive neurodegenerative disease that affects the central nervous system, particularly impairing movement control.
- Conditions
- Pain Management, Regional Anesthesia, Deep Brain Stimulation, Parkinsons Disease
- Trial name
- NCT07176494
- Testing
- Patients who underwent surgery under general anesthesia, Patients who underwent surgery under regional anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara Etlik City Hospital
Atrial Fibrillation, Ablation
The Deep Sedation for Ablation Study
Catheter ablation (CA) is an established therapeutic option for patients with symptomatic atrial fibrillation (AF). During the procedure, patients are usually sedated and analgesized, most commonly by administration of Propofol…
- Conditions
- Atrial Fibrillation, Ablation, Sedation, Propofol
- Trial name
- NCT03844841
- Testing
- Propofol, Dexmedetomidine
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Thyroid Neoplasm
Comparison Between Remifentanil Target-controlled Infusion and Dexmedetomidine Bolus Administration for Smooth Emergence From General Sevoflurane Anesthesia
Remifentanil target-controlled infusion and dexmedetomidine single-dose administration are known to reduce airway response and haemodynamic stimulation during anaesthetic recovery.
- Trial name
- NCT01617694
- Testing
- dexmedetomidine, Normal Saline
- Where
- South Korea
- Volunteers
- 65 people
- Sponsor
- Yonsei University
Nociceptive Pain, Surgical Procedure, Unspecified
Automatic Remifentanil Administration Guided by ANI During Propofol Anesthesia
Prospective Randomized Monocentric Clinical Trial during propofol anesthesia. The aim of the study is to test whether the use of a medical device designed to automatically administer remifentanil during surgery based on expert…
- Trial name
- ANI-LOOP (NCT03556696)
- Testing
- ANI-REMI-loop, remifentanil pK/pD target administration device, Remifentanil
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Lille
Anxiety, Preoperative
Management of Preoperative Anxiety in Children: Could a Lollipop Be the Solution?
The aim of the study is to evaluate the effectiveness of distraction using a lollipop versus premedication with intranasal midazolam to manage preoperative anxiety in pediatric anesthesia.
- Trial name
- NCT06670846
- Testing
- Lollipop, distraction using intranasal Midazolam
- Where
- Tunisia
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Tunis University
Abdominal Hysterectomy, General Anesthesia
Intravenous Administration of Magnesium Sulfate in Hysterectomy Cases
In our study, it was aimed to show the contribution of intraoperative intravenous magnesium sulfate administration to peroperative opioid consumption and postoperative analgesia.
- Conditions
- Abdominal Hysterectomy, General Anesthesia, Magnesium Sulfate
- Trial name
- NCT05644873
- Testing
- magnesium sulfate group, control group saline
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Anesthesia, Airway Device
Laryngeal Mask in Upper Gastrointestinal Procedures
Diagnostic and operative procedures of upper gastrointestinal (GI) tract are very common in all patients. Some procedures are difficult to tolerate because of long duration, prone position or significant stimulation of the upper…
- Conditions
- Anesthesia, Airway Device, C.Surgical Procedure; Gastrointestinal
- Trial name
- SeoMask (NCT03567928)
- Testing
- Sedation with Gastro Cuff Pilot Laryngeal Mask, Propofol
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Ospedale San Raffaele
Acute Ischemic Stroke
IDEAL Blood Pressure Management During Endovascular Therapy for Acute Ischemic Stroke
The ideal blood pressure management strategy during endovascular therapy (EVT) for acute ischemic stroke has not been defined. The aim of this pilot randomized clinical trial is to determine whether randomization to a standard…
- Trial name
- IDEAL (NCT04749251)
- Testing
- Individualized blood pressure management, Standard blood pressure management
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Hydrocephalus, Brain Damage
The Role of Neurofilament Light (NfL) in Patients With Hydrocephalus
Neurofilament Light Chain Protein (NfL) has been found by many studies as a sensitive biomarker of neuronal damage from several reasons, e.g.
- Conditions
- Hydrocephalus, Brain Damage, General Anesthetics Toxicity
- Trial name
- NCT05399602
- Testing
- Lumbar puncture, External lumbar drainage, Lumbar infusion test
- Where
- Czechia
- Volunteers
- 41 people
- Sponsor
- University Hospital Hradec Kralove
Adenotonsillectomy, Preoperative Anxiety
Timing Of Midazolam İn Children Undergoing Adenotonsillectomy: Effects On Stress, Cortisol, And Recovery
This study is a prospective, randomized, controlled clinical trial designed to evaluate the optimal timing of midazolam administration in children undergoing adenotonsillectomy.
- Conditions
- Adenotonsillectomy, Preoperative Anxiety, Surgical Stress Response, Postoperative Pain
- Trial name
- Timing-Midazol (NCT07622641)
- Testing
- Midazolam (Oral), Midazolam (Intravenous)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Erzurum City Hospital
Postoperative Pain, Obesity
Comparison of Two Magnesium Sulfate Protocols in Opioid-Free Anesthesia for Bariatric Surgery
This retrospective observational study aims to compare postoperative morphine consumption in patients undergoing bariatric surgery with opioid-free anesthesia (OFA) using two different intravenous magnesium sulfate administration…
- Conditions
- Postoperative Pain, Obesity, Bariatric Surgery, Opioid-free Anesthesia
- Trial name
- OFA-MG (NCT07077031)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Hospital HM Nou Delfos
Unexpected Difficult Airway, Intubation;Difficult
Initiation of Airway Code: the Role of the Airway Team in Unexpected Difficult Airways
The aim of our study is to observationally examine our unexpected difficult airway incidence and intervention times. In addition, it is aimed to discuss the clinical effect of a team specialized in airway intervention intervening…
- Conditions
- Unexpected Difficult Airway, Intubation;Difficult, Airway Management
- Trial name
- NCT06448377
- Testing
- Videolaryngoscopy, FOB, FOB+Aintree
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Kocaeli City Hospital