Clinical trials: Anesthesia Management
Hemodynamic Instability During Anesthesia, High Risk Surgery
Focused TTE for Hemodynamic Instable High Risk Patients
Focused transthoracic echocardiography (TTE) is a technique, which allows quick and non-invasive diagnosis and monitoring in hemodynamic instable patients.
- Trial name
- NCT01811914
- Testing
- intraoperative TTE
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Philipps University Marburg
Postoperative Delirium
Manual vs Automated Anesthesia : Impact On The Incidence Of POCD
This study will be the first study to report the combined use of three independent closed-loop systems together to assist clinicians in titrating anesthesia, analgesia, fluid and optimize ventilation in frailty old patients…
- Trial name
- NCT03148730
- Testing
- closed-loop group
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- Erasme University Hospital
Intubation, Pediatric, Intubation; Difficult or Failed
Validation of the POGO Score for Classification of Videolaryngoscopy in Children - Post-hoc Analysis of the PeDiAC Study
It has been assumed that the percentage of glottic opening (POGO) score might enhance the classification of videolaryngoscopic tracheal intubation by offering a more objective rating of glottic exposure but studies in children…
- Conditions
- Intubation, Pediatric, Intubation; Difficult or Failed, Airway Management, Airway Complication of Anesthesia
- Trial name
- POGO-KIDS (NCT07115407)
- Where
- Germany
- Volunteers
- 809 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Anesthesia, General
Automated Anesthesia During Bronchoscopy
The purpose of this study is to compare manual administration of propofol and remifentanil and dual closed-loop using bispectral index as the control variable during rigid bronchoscopy.
- Trial name
- NCT00571181
- Testing
- Closed-loop system, TCI (Infusion Toolbox)
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Hopital Foch
Pulpitis
Efficacy of Oral Prednisolone on Pain Reduction in Emergency Care of Acute Irreversible Pulpitis
Irreversible pulpitis is an inflammatory condition of the dental pulp, highly painful, representing one of the main reasons for consulting dental emergency.
- Trial name
- PULPISOLONE (NCT02629042)
- Testing
- Partial endodontic treatment under local and/or locoregional anesthesia, prednisolone
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Bordeaux
Anaesthesia, Anesthesia Depth Monitoring
Monitoring the Depth of Anesthesia and Nociception During the Induction of General Anesthesia in Pediatric Patients
Perioperative assessment of adequate depth of anesthesia and analgesia is currently a recommended part of routine anesthesia practice for all surgical procedures.
- Trial name
- ANIGAPP (NCT07245654)
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Brno University Hospital
Knee Osteoarthritis, Total Knee Arthroplasty
Remimazolam Total Intravenous Anesthesia Under Analgesia Nociception Index-guidance
The investigators hypothesized that intraoperative opioid consumption would be different between remimazolam and propofol if the ANI-guided remifentanil continuous infusion rate was adjusted when the depth of anesthesia was…
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty, Remimazolam
- Trial name
- NCT05322902
- Testing
- remimazolam group, propofol group
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Gangnam Severance Hospital
Severty of Hpotention
Comparing Sitting Versus Lateral Position During Spinal Anesthesia on the Severity of Hypotension:
This study aimed to assess the effect of sitting and lateral positions on the severity of hypotension during the initiation of spinal anesthesia in elective cesarean section. There will be Sitting and Lateral groups in the study.
- Trial name
- NCT06149572
- Testing
- lateral position procedure, sitting position porocedure
- Where
- Ethiopia
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Wollo University
Anesthesia
Closed-loop Fluid Administration System: Pilot Study to Evaluate Feasibility
The investigators want to test during anesthesia the feasibility of a closed-loop automated fluid replacement system using cardiac output monitoring as the input value.
- Trial name
- NCT01882075
- Testing
- Open loop, Closed-loop
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Hopital Foch
Anesthesia, General, Hemodynamics
Observation on Administration of Propofol at Different Titration Endpoints
Propofol has a rapid onset and short duration of action, making it widely used for induction of general anesthesia. However, its prominent drawback is circulatory depression.
- Trial name
- OAPDTE (NCT06685198)
- Testing
- Titrated administration of propofol to an OAA/S score of 1 as the endpoint, Titrated administration of propofol to an OAA/S score of 2 as the endpoint, Titrated administration of propofol to a BIS value ≤ 60 as the endpoint
- Where
- China
- Volunteers
- 258 people
- Sponsor
- SanQing Jin
Post Operative Pain, Thoracic Cancer
Thoracic Paravertebral Block With Methylene Blue Visual Confirmation for Postoperative Pain After VATS Lobectomy
The goal of this study is to compare the efficacy in controlling postoperative pain of paravertebral block (PVB) with methylene blue visual confirmation and thoracic epidural anesthesia (TEA).
- Trial name
- NCT05812521
- Testing
- Paravertebral block with methylene blue, Thoracic Epidural Anesthesia
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Campania Luigi Vanvitelli
Airway Management, Positive End Expiratory Pressure
Airway Effects of PEEP During Anesthesia Induction.
This study investigates airway effects of PEEP during maskventilation at anesthesia induction. Four patient groups will be ventilated with different PEEP and driving pressures to evaluate time to open airway after start of…
- Conditions
- Airway Management, Positive End Expiratory Pressure, Mask-ventilation, Anesthesia Induction
- Trial name
- NCT02920879
- Testing
- PEEP-level, driving pressure
- Volunteers
- 120 people
- Sponsor
- Region Örebro County
Hypotension on Induction
PoCUS Guided Fluids to Prevent Post-induction Hypotension
Hypotension is a common side-effect of general anesthesia induction, and is related to adverse outcomes, including a significantly increased risk of one-year mortality.
- Trial name
- HIPO (NCT05424510)
- Testing
- Ringer's Lactate, IV line
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Mount Sinai Hospital, Canada
Pelvic Floor Disorders
Factors Influencing Hemodynamic Stability and Its Management in Patients Undergoing Pelvic Surgery Under Spinal and GA
Patients are at risk for hemodynamic instability both during and after surgery, as it is an independent predictor of long-term patient morbidity and length of hospital stay.
- Trial name
- NCT06767397
- Testing
- general anesthesia
- Where
- Pakistan
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Superior University
Children Under General Anaesthesia
Tablet-based Interactive Distraction Preoperative Anxiety in Children: A Randomized Controlled Trial
Children develop anxiety during the induction of anaesthesia and video-games might reduce or alleviate it. The investigators intend to conduct a clinical trial to study the effect of tablet-based interctive games on alleviating…
- Trial name
- TABLET (NCT03531359)
- Testing
- TIBD, Midazolam
- Where
- Chile
- Volunteers
- 112 people
- Sponsor
- Universidad de Valparaiso
Anesthesia
Impact of Intraoperative Fluid Management on Electrolyte and Acid-base Variables
During major surgical procedures, intravascular volume is maintained with the administration of isotonic fluids such as Lactated Ringers (LR), Normal Saline (NS) or Normosol-R.
- Trial name
- NCT03054922
- Testing
- Normal Saline, Lactated Ringer, Normosol-R Inj
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Nationwide Children's Hospital
Anesthesia, Airway Complication of Anesthesia
Apnoeic Oxygenation During Pediatric Tracheal Intubation
The goal of this randomized, controlled, single-blinded clinical trial is to evaluate the effectiveness of apnoeic Oxygenation in pediatric anesthesia.
- Conditions
- Anesthesia, Airway Complication of Anesthesia, Anesthesia; Adverse Effect
- Trial name
- NCT06576596
- Testing
- apnoeic Oxygenation
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital Heidelberg
Pain, Postoperative, Rebound Pain
Intravenous Dexamethasone With Single-Shot Versus Continuous Brachial Plexus Block for Rebound Pain After Shoulder Surgery
Shoulder surgery often causes severe pain after the operation. To control this pain, doctors commonly perform a nerve block (interscalene brachial plexus block), which numbs the shoulder area.
- Conditions
- Pain, Postoperative, Rebound Pain, Shoulder Injuries, Rotator Cuff Injuries
- Trial name
- NCT07699744
- Testing
- Dexamethasone (IV), Single-shot interscalene brachial plexus block, Continuous interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Pain, Postoperative, Pain, Acute
Intravenous Methadone in Perioperative Acute and Chronic Management in Chinese Adult Cardiac Surgical Patients
Despite modern day improvements in pain treatment and availability of different analgesic modalities, suboptimal postoperative pain control remains an issue in cardiac surgical patients.
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Anesthesia
- Trial name
- NCT05913284
- Testing
- Methadone, Morphine
- Where
- Hong Kong
- Volunteers
- 86 people
- Sponsor
- Chinese University of Hong Kong
Depression, Postpartum, Pregnancy
Labor Pain and Postpartum Behavioral Health Outcomes Study
In this pilot prospective longitudinal observational study, women who are pregnant and who will be experiencing childbirth for the first time will be recruited at the third trimester and observed longitudinally for psychiatric…
- Conditions
- Depression, Postpartum, Pregnancy, Child Development, Pain
- Trial name
- LPPD (NCT02692404)
- Where
- 2 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh