Clinical trials: Anesthesia Management
Postoperative Analgesia, Pain Management
Erector Spinae Plane Block Versus Retrolaminar Block for Analgesia in Percutaneous Nephrolithotomy
The study will investigate the effects of ultrasound-guided ESPB and RLB on intraoperative and postoperative analgesia in patients undergoing PCNL to identify a safe and effective regional block method for postoperative analgesia
- Conditions
- Postoperative Analgesia, Pain Management, PCNL, Regional Anesthesia Block
- Trial name
- NCT06710444
- Testing
- ultrasound-guided erector spinae plane block, ultrasound-guided retrolaminar plane block
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Pain
SFIB vs Anterior QLB in Total Hip Arthroplasty
Quadratus lumborum block (QLB) is a facial plane block defined to provide analgesia from T7-L3 dermatomes. There are articles reporting that it is an effective analgesic method in hip surgeries.
- Trial name
- NCT05684471
- Testing
- Ultrasound Guided Suprainguinal Fascia iliaca Block, Ultrasound Guided Anterior Quadratus Lumborum Block
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Samsun University
Skin Graft Complications, Pain Management
The Rule of Bupivacaine Hydrochloride in Skin Graft Donor Site
Split Thickness Skin Graft is frequently utilized for reconstructing skin loss of various causes. Unfortunately, the donor site of the STSG has an unavoidable, annoying post-operative pain
- Trial name
- NCT06766474
- Testing
- Bupivacain
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Minia University
Endotracheal Intubation, Gastrointestinal Endoscopy
Application of Lateral Position Digestive Endoscopy-Guided Endotracheal Intubation in Anesthesia for Endoscopic Diagnosis and Therapy
This case series study evaluated whether placing a breathing tube using a camera (gastrointestinal endoscope) is safe and effective for patients lying on their left side during stomach and intestine exams under anesthesia.
- Conditions
- Endotracheal Intubation, Gastrointestinal Endoscopy, Airway Management, Lateral Position
- Trial name
- NCT06990490
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Changlong Qiao
Postoperative Sore Throat, Endotracheal Intubation
Scheduled Endotracheal Tube Cuff Pressure Management and Postoperative Sore Throat
This randomized controlled trial evaluated whether scheduled measurement and adjustment of endotracheal tube cuff pressure using a handheld manometer could reduce postoperative sore throat in adults undergoing elective surgery…
- Trial name
- NCT07842081
- Testing
- Handheld Endotracheal Tube Cuff Manometer, Pilot-Balloon Palpation
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Hitit University
Anesthesia, Surgery
Association Between Clinical Effect of Continuous Morphine Administration After Surgery and Pharmacogenetics
Identification of the genetic polymorphisms that could be correlated either with a better clinical response or with a major predisposition of patients to develop tolerance and/or side effects to the treatment with morphine.
- Trial name
- NCT01233219
- Testing
- morphine chlorhydrate
- Where
- Italy
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Airway Management, Respiration, Artificial
Non-inferiority Trial Between Sotair® Device Attached to Manual Resuscitator Versus Mechanical Ventilation
Effective respiratory ventilation is achieved by moving the right amount of air in and out of the lungs while keeping the pressures at a safe level.
- Trial name
- NCT06117683
- Testing
- ADULT Sotair Device
- Where
- United States
- Volunteers
- 334 people
- Sponsor
- Rhode Island Hospital
Knee Osteoarthritis, Postoperative Pain Management
Effect of iPACK and BiFeS Blocks on Quality of Recovery After Total Knee Arthroplasty
This prospective, randomized, double-blind clinical trial aims to compare the effects of two different posterior knee analgesia techniques-iPACK block (Interspace Between the Popliteal Artery and the Capsule of the posterior…
- Conditions
- Knee Osteoarthritis, Postoperative Pain Management, Total Knee Arthroplasty
- Trial name
- BiFeS-TKA (NCT07248072)
- Testing
- Adductor Canal Block (ACB) Only, IPACK block, BiFeS Block
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Ataturk University
Anesthesia, Conduction, Pain Management
The Effects of Ultrasound-guided Serratus Plane Block During Video-assisted Thoracoscopic Lobectomy
This study evaluates the effects of serratus plane block on intraoperative opioid consumption, emergence time and hemodynamic stability in patients undergoing video-assisted thoracic surgery.
- Trial name
- NCT03718377
- Testing
- Serratus plane block, General anesthesia only
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Kyungpook National University Hospital
Post-Dural Puncture Headache
Trans-nasal Sphenopalatine Ganglion Block Versus Ultrasound-guided Bilateral Greater and Lesser Occipital Nerve Block for Management of Post-Dural Puncture Headache.
Post-Dural Puncture Headache (PDPH) is a complication associated with spinal anesthesia. While conventional treatments are available, the Epidural Blood Patch (EBP) is considered the gold standard.
- Trial name
- TNSPGB /GALONB (NCT06705244)
- Testing
- Trans-nasal sphenopalatine nerve block, Greater and lesser occipital nerve block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Depression, Postpartum, Pregnancy
Labor Pain and Postpartum Behavioral Health Outcomes Study
In this pilot prospective longitudinal observational study, women who are pregnant and who will be experiencing childbirth for the first time will be recruited at the third trimester and observed longitudinally for psychiatric…
- Conditions
- Depression, Postpartum, Pregnancy, Child Development, Pain
- Trial name
- LPPD (NCT02692404)
- Where
- 2 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Female, Male
SEx-specific Differences in Cardiac Surgery Patients (SECS).
The aim of this study is to evaluate the differences between females and males undergoing cardiac surgery. The investigators will look at perioperative factors such as adaption of body weight, previous medical history…
- Conditions
- Female, Male, Surgery, Cardiac
- Trial name
- SECS (NCT06554925)
- Testing
- Cardiac surgery
- Where
- Netherlands
- Volunteers
- 10,000 people
- Sponsor
- Jennifer Breel
Deafness, Blindness
Workshops for Veterans With Vision and Hearing Loss
This is a pilot study of workshops to help Veterans with both vision and hearing loss live a happier, fuller and less stressful life. The results will be used to guide the development of a large scale clinical trial.
- Trial name
- DSLW (NCT01109576)
- Testing
- DSL Workshop
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- US Department of Veterans Affairs
Ringer's Lactate
Fluid Management in the Post Anesthesia Care Unit
Fluid therapy is a cornerstone in patient therapy perioperatively. Many studies have addressed the amount of fluid administered (restrictive vs liberal strategies).
- Trial name
- NCT03799250
- Testing
- Ringer lactate, standard care
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Rabin Medical Center
Opioid Use, Spine Fusion
Effectiveness of Combining Erector Spinea Block With Non Opioid Infusions as Opioid Free Anesthesia in Spine Surgeries.
opioid free anesthesia consists of combination of pharmacological and non pharmacological modalities that target different pathways of pain mechanism.
- Trial name
- NCT05850468
- Testing
- fentanyl infusion after general anesthesia and erector spinea block, lidocaine 2% and dextometometidine infusion after general anesthesia and erector spinea block
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Cancer, Surgery
Anesthesia Feasibility Study With the CONCERT-CL® Station
This is a feasibility study of anesthesia in closed loop with the CONCERT-CL® station, on the effect of the hypnotic agent, measured by the bispectral index of the electroencephalogram, to maintain the hypnosis level within the…
- Trial name
- CONCERT (NCT02889718)
- Testing
- CONCERT-CL® station, Surgery
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Institut Cancerologie de l'Ouest
Postoperative Pain, Tonsillectomy
Sphenopalatine Ganglion Block for Pain Relief After Pediatric Adenotonsillectomy
The aim of this clinical trial is to discover whether sphenopalatine ganglion block (SPGB) reduces postoperative pain in children aged 2 to 13 years undergoing tonsil surgery (with or without adenoid removal).
- Conditions
- Postoperative Pain, Tonsillectomy, Adenotonsillectomy
- Trial name
- SPARK (NCT07793617)
- Testing
- Sphenopalatine ganglion block (Ropivacaine)
- Volunteers
- 145 people
- Sponsor
- Vinícius C Quintão, MD, MSc, PhD
Anesthesia, Airway Management
Classification and Prediction of Difficult Awake Tracheal Intubation With Flexible Bronchoscopes
Airway management problems are key drivers for anesthesia-related adverse events. Awake tracheal intubation using flexible bronchoscopes with preserved spontaneous breathing (ATI:FB) is a recommended technique to manage difficult…
- Conditions
- Anesthesia, Airway Management, Intubation, Intratracheal, Bronchoscopy
- Trial name
- AirWake (NCT06953414)
- Where
- Germany
- Volunteers
- 313 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Anterior Cervical Discectomy, Serratus Posterior Superior Intercostal Plane Block
Postoperative Analgesic Efficacy of SPSIPB in Anterior Cervical Discectomy
Anterior cervical discectomy is an operation performed for complaints of pain, numbness or loss of strength due to cervical disc disease.
- Conditions
- Anterior Cervical Discectomy, Serratus Posterior Superior Intercostal Plane Block, Postoperative Pain Management, Postoperative Pain
- Trial name
- NCT07238621
- Testing
- The group treated with intravenous analgesics, Serratus posterior superior intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cumhuriyet University
Anesthesia
Dose-Escalation Safety and Pharmacokinetic Study of K305
The purpose of this study is to determine the pharmacokinetics/pharmacodynamics and safety of a nasal spray containing the anesthetic drug tetracaine in combination with oxymetazoline
- Trial name
- NCT01304316
- Testing
- Tetracaine HCl 3% and Oxymetazoline HCl 0.05%
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- St. Renatus, LLC