Clinical trials: Anesthesia Recovery
Rocuronium, Lumbar Discectomy
Continuous Infusion and Bolus Doses of Rocuronium During Lumbal Discectomy, Muscle Strength and Patient Recovery
The continuous infusion of rocuronium during general anesthesia for a lumbar discectomy enables better muscle strength recovery, and a better quality of patient recovery as measured by questionnaire.
- Conditions
- Rocuronium, Lumbar Discectomy, Recovery
- Trial name
- NCT04236050
- Testing
- Rocuronium
- Where
- Croatia
- Volunteers
- 80 people
- Sponsor
- Clinical Hospital Centre Zagreb
Neuromuscular Blockade
Comparison of Mechanomyographic 100 Versus 200 Hz 5 Second Tetanic Fade Ratios During Neuromuscular Block Recovery
Two recent pilot studies suggested the potential interest of 100 and 200 Hz tetanic stimulations to detect with mechanomyography (MMG) very low levels of residual neuromuscular blockade (NMB).
- Trial name
- NCT05474638
- Testing
- Isometric Thumb Force (isometric mechanomyography) compared to TOF-Watch SX (acceleromyography)
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire UCLouvain Namur
Total Knee Arthroplasty, Regional Anesthesia
Effects of 10 Versus 20 mL Local Anesthetic for Popliteal Plexus Block on Opioid Consumption, Pain, and Patient-Reported Outcomes After Total Knee Arthroplasty
This trial aims to assess the analgesic effect of Popliteal Plexus Block (PPB) with 10 mL versus 20 mL of Bupivacain 5 mg/mL, when applied as an adjunct treatment to a multimodal analgesic regimen following primary total knee…
- Conditions
- Total Knee Arthroplasty, Regional Anesthesia, Multimodal Analgesic Approach, Postoperative Opioid-related Complications
- Trial name
- NCT06908837
- Testing
- Bupivacaine
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Regionshospitalet Silkeborg
Incomplete Reversal of Neuromuscular Block
Quality of Recovery After Reversal With Neostigmine or Sugammadex.
This study will compare patient recovery measures after reversal of neuromuscular blockade with neostigmine or sugammadex after surgery.
- Trial name
- NCT02909439
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stony Brook University
Patients Undergoing Robotic Surgery
Quality of Recovery After Robotic Surgery
Robotic approach to laparoscopic surgery has greatly facilitated undertaking complex surgery inside the abdominal cavity with ease.
- Trial name
- NCT03659539
- Testing
- PROPOFOL, Desflurane
- Where
- India
- Volunteers
- 120 people
- Sponsor
- Nitin Sethi, DNB
Anesthesia, Spinal
Comparison of Clorotekal and Bupivacaine for Short Obstetric Surgery
The following obstetric procedures are commonly performed with spinal anesthesia on labor and delivery: bilateral tubal ligation, external cephalic version, cerclage insertion, cerclage removal, minimally invasive fetal surgery…
- Trial name
- CLIMB (NCT03967288)
- Testing
- Chloroprocaine Injection [Clorotekal], Bupivacaine Hydrochloride 0.75% Injection Solution
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Post-anesthesia Recovery
Effects of Esketamine on Recovery of Consciousness After Propofol Anesthesia
Esketamine is an antagonist of N-methyl-d-aspartate (NMDA) receptor different from other gamma-aminobutyric acid (GABA) receptor agonists.
- Trial name
- NCT06430645
- Testing
- Esketamine, Saline
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Tiantan Hospital
Anesthesia
Comparative Study of Recovery Characteristics Between Remimazolam Anesthesia With Flumazenil and Desflurane Anesthesia for Closed Reduction of Nasal Bone Fracture
The goal of this prospective, randomized study is to compare recovery characteristics between remimazolam anesthesia with flumazenil and desflurane anesthesia in patients undergoing closed reduction of nasal bone fracture.
- Trial name
- NCT05774366
- Testing
- Remimazolam, Desflurane
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Daegu Catholic University Medical Center
Postoperative Pain, Psychological Factors
Psychosocial Factors and Postoperative Pain in Aesthetic Breast Surgery
This study investigates the relationship between psychosocial factors, particularly self-esteem and personality traits, and postoperative pain in patients undergoing aesthetic breast surgery.
- Conditions
- Postoperative Pain, Psychological Factors, Breast Surgery, Aesthetic Surgery
- Trial name
- NCT06707818
- Testing
- Preoperative Interventions, Intraoperative Interventions, Postoperative Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- V.K.V. American Hospital, Istanbul
Flumazenil Adverse Reaction, Remimazolam
Effects of Flumazenil on Recovery After Total Intravenous Anesthesia With Remimazolam
Remimazolam is a medication that has the advantage of a short half-life and reversibility with flumazenil. In clinical situations, the use of flumazenil for the reversal of sedation is common, but there is no precise indication…
- Conditions
- Flumazenil Adverse Reaction, Remimazolam, Hip Joint, Elderly Patients
- Trial name
- NCT05939674
- Testing
- Flumazenil, normal saline
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Pusan National University Yangsan Hospital
Nerve Block, Coronary Artery Bypass
Comparison of Erector Spinae Plane Block and Transversus Thoracic Muscle Plane Block in Coronary Artery Surgery
The main objective of this study is to evaluate postoperative pain intensity comparatively between erector spinae plane block and transversus thoracic muscle plane block in patients undergoing open coronary artery surgery.
- Conditions
- Nerve Block, Coronary Artery Bypass, Anesthesia and Analgesia
- Trial name
- NCT06709625
- Testing
- Transversus thoracis plane block, Erector spina plane block (ESP)
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Ankara City Hospital Bilkent
Pituitary Adenoma
Comparison of Postoperative Recovery of Sevoflurane and Propofol After Transsphenoidal Surgery
Currently, total intravenous anesthesia (TIVA) and inhaled anesthesia are both commonly used for transsphenoidal pituitary adenoma resection.
- Trial name
- NCT05822817
- Testing
- sevoflurane, propofol
- Where
- China
- Volunteers
- 252 people
- Sponsor
- Peking Union Medical College Hospital
Laparoscopy, Anesthesia Recovery Period
Deep Neuromuscular Block for Laparoscopic Surgery
Trial summary: deep neuromuscular block is proposed as a technique to improve operative conditions for laparoscopy. Early clinical data would suggest that there may also be patient benefits beyond the operative period related to…
- Trial name
- DEEPBLOCK (NCT03034577)
- Testing
- Sugammadex, Neostigmine
- Where
- 4 sites in Australia
- Volunteers
- 350 people
- Sponsor
- University of Melbourne
Anaesthesia
Study of Anaesthesia Costs and Recovery Profiles
The purpose of this study is to compare the perioperative hemodynamic parameters, recovery profiles and cost containment of sevoflurane and propofol based general anesthesia for otorhinolaryngeal surgery.
- Trial name
- SACRP (NCT02920749)
- Testing
- Sevoflurane group A, Sevoflurane group B, Propofol group C
- Where
- Hungary
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Best Technique for Pediatric Anesthesia
Recovery of TIVA vs Inhalation in Pediatric Anesthesia
Compare recovery profile from TIVA and that of total inhalational anesthesia in ambulatory pediatric tonsillectomy and which strategy is more safe and less cost and more smooth in pediatric anesthesia.
- Trial name
- NCT06215833
- Testing
- Propofol, Sevoflurane
- Volunteers
- 120 people
- Sponsor
- Assiut University
Total Hip Arthroplasty (THA), Femoral Neck Fractures
PNB Anesthesia Improves Older Patients' Postoperative Early Recovery Outcomes After Total Hip Arthroplasty
Early postoperative rehabilitation is an important issue for total hip arthroplasty, especially in older patients. This retrospective clinical trial is to assess the impact of peripheral nerve block anesthesia versus general…
- Trial name
- NCT07163598
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 516 people
- Sponsor
- RenJi Hospital
Brain Tumor
Quality of Recovery Awake Versus Asleep Craniotomy
Awake craniotomy (AC) is an anesthetic and surgical technique commonly used to resect tumors involving or adjacent to the eloquent or motor cortices, those portions of the brain that are responsible for language and motor skills…
- Trial name
- NCT02228993
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Northwestern University
Aneurysm Cerebral
Dexmedetomidine Improves Recovery After Cranial Aneurysm Surgery
Dexmedetomidine induces analgesic and sedative effects and is reported to decrease agitation during emergence after general anesthesia in various surgeries.
- Trial name
- DACA (NCT03355534)
- Testing
- Intravenous dexmedetomidine, nasal dexmedetomidine, intravenous saline
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Zhihong LU
Lung Neoplasms
Effects of Nonintubated Versus Intubated General Anesthesia on Recovery After Thoracoscopic Lung Resection
Lung cancer is the leading cause of cancer death in Taiwan and worldwide. With the advancement of thoracoscopic technique, thoracoscopic surgery has emerged as a reasonable option for the management of early-stage non-small cell…
- Trial name
- NCT02393664
- Testing
- propofol, bupivacaine, sevoflurane, rocuronium
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Restlessness, Pain
Effects of Dexmedetomidine on Stress Response and Postoperative Analgesia
Dexmedetomidine is a highly selective α2 adrenoreceptor agonist approved by the US FDA for short-term postoperative sedation and analgesia.It can also reduce the stress response without respiratory depression.
- Trial name
- NCT01517932
- Testing
- dexmedetomidine
- Volunteers
- 60 people
- Sponsor
- Fang Luo