Clinical trials: Anesthesia Spinal
Spinal Anesthesia-induced Hypotension, Vitamin D Deficiency
Effect of Vitamin D Deficiency on the Frequency and Severity of Spinal Anesthesia-Induced Hypotension in Pregnant Women Undergoing Cesarean Section
Spinal anesthesia-induced hypotension remains a common and significant complication during cesarean sections, posing risks for both mother and fetus.
- Conditions
- Spinal Anesthesia-induced Hypotension, Vitamin D Deficiency, Cesarean Section
- Trial name
- NCT07057362
- Testing
- Intraoperative Hemodynamic Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 177 people
- Sponsor
- Duzce University
Shivering, Nausea and Vomiting, Postoperative
Dexmedetomidine After Cesarean for the Treatment of Nausea and Shivering
This is a randomized double blinded trial to determine if a small dose of dexmedetomidine can prevent and relieve nausea and shivering, two of the more common complaints after cesarean delivery.
- Trial name
- NCT03370562
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Beth Israel Deaconess Medical Center
Fascia Iliaca Compartmental Block, Femoral Thrombectomy
Ultrasound-Guided Fascia Iliaca Compartmental Block Versus Spinal Anesthesia in Femoral Thrombectomy
This study aims to assess the efficiency of Fascia Iliaca Compartmental Block in patients undergoing femoral thrombectomy versus spinal anesthesia.
- Conditions
- Fascia Iliaca Compartmental Block, Femoral Thrombectomy, Spinal Anesthesia
- Trial name
- NCT06745986
- Testing
- ultrasound guided fascia iliaca compartment block ( bupivacaine 0.25% ), Spinal Anesthesia (bupivacaine)
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Port Said University hospital
Postoperative Delirium
Dexmetomedine for Post Operative Delirium in Elderly Patients Undergoing Elective Total Knee Replacement Under Spinal Anesthesia
Postoperative delirium is a geriatric syndrome occurring after anesthesia and surgery which manifests as acute alterations in mental status, involving changes in cognition, attention, and levels of consciousness that tend to…
- Trial name
- NCT05707741
- Testing
- dexmetomedine infusion
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Anesthesia
Efficacy, Safety and Limitations of Spinal Block for All Infants Under 3 Months
Spinal anesthesia (SA) has been shown to be a viable alternative to general anesthesia (GA) for infants and children for a variety of surgical procedures.
- Trial name
- NCT06871995
- Testing
- spinal block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Spinal Stenosis, Lumbosacral Region
Stability Comparison of TIVA and Sevoflurane in Prone Spinal Surgery(TIVA:Total Intravenous Anesthesia)
Key Points: 1. Objective: o To compare the effects of Total Intravenous Anesthesia (TIVA) and sevoflurane anesthesia on respiratory mechanics, hemodynamic parameters, and neuromonitoring during prone position spinal surgeries. 2.
- Trial name
- TIVA (NCT06558695)
- Testing
- Sevoflurane, TIVA
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Postoperative Pain Management, Obstetric Anesthesia
Effect of Bilateral Ultrasound-Guided TAP Block on Quality of Recovery in Cesarean Delivery Patients Receiving Intrathecal Morphine
This prospective, assessor-blinded observational cohort study will investigate the effect of adding bilateral ultrasound-guided transversus abdominis plane (TAP) block to standard intrathecal morphine (ITM) analgesia on the…
- Conditions
- Postoperative Pain Management, Obstetric Anesthesia, Recovery From Anesthesia
- Trial name
- QoR-TAP (NCT07145619)
- Testing
- Spinal Anesthesia with Intrathecal Morphine Only, Spinal Anesthesia with Intrathecal Morphine plus Bilateral TAP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- MEHMET GÖKHAN TAFLAN
Osteoarthritis, Hip, Osteoarthritis, Knee
Spinal Anaesthesia vs. General Anaesthesia for THA, TKA and UKA
The goal of this randomized clinical trial is to investigate the postoperative recovery following hip and knee arthroplasty procedures depending on the use of either spinal anaesthesia (SA) or general anaesthesia (GA).
- Trial name
- RCT SAGA (NCT05706844)
- Testing
- Spinal anesthesia, General anaesthesia
- Where
- 2 sites in Denmark
- Volunteers
- 222 people
- Sponsor
- Anders Troelsen
Scoliosis, Spine Deformity
Post-Hoc Cost-Utility Analysis of Ultrasound-Guided Erector Spinae Plane (ESP) Block Versus Total Intravenous Anesthesia (TIVA) in Posterior Scoliosis Correction Surgery: Evidence From the Egyptian EQ-5D-5L Value Set
Posterior scoliosis correction surgery is associated with sever postoperative pain that necessitate high perioperative opioid doses to alleviate pain .
- Trial name
- NCT07470567
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- National Bank Hospital
Hypotension, Pregnancy
Intravenous Ondansetron to Attenuate the Hypotensive, Bradycardic Response to Spinal Anesthesia in Healthy Parturients
The investigators hypothesize that given prophylactically, intravenous ondansetron will attenuate the drop in blood pressure and heart rate frequently seen after spinal anesthesia.
- Trial name
- NCT01414777
- Testing
- ondansetron
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Virginia
Breech Presentation
Impact of Analgesia on Success of External Version: Comparison of Spinal Anesthesia Versus Sedation
At the time of birth, nearly 5% of children are in breech presentation. This type of presentation requires a medical environment and leads to more frequent use of Caesarean sections.
- Trial name
- RaVem (NCT02801201)
- Testing
- Midazolam, Bupivacaine
- Where
- France
- Volunteers
- 186 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Preeclampsia
Spinal Anaesthesia and Severe Preeclampsia
The use of spinal anesthesia in pre-eclamptic pregnant woman is of considerable benefit, as these patients present particular hazards with general anaesthesia, such as concerns for rapid airway control and cerebral blood flow…
- Trial name
- NCT02633995
- Testing
- spinal anaesthesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Airway Reactivity, Hemodynamic Stability During Anesthesia
ETCO₂ Targeting and Cerebral Oxygenation
This study looked at a safer way to prepare patients for anesthesia before major spinal surgery. Instead of using advanced or complex oxygen devices, the approach will use standard oxygen methods, guided by the patient's…
- Trial name
- NCT07526077
- Testing
- regional cerebral oxygen saturation
- Where
- Saudi Arabia
- Volunteers
- 70 people
- Sponsor
- Prince Sultan Military Medical City
Hypotension, Spinal Anesthesia
Prophylactic Ondansetron for Preventing Spinal Anesthesia-Induced Hypotension in Elective Cesarean Section
Spinal anesthesia is the preferred technique for elective cesarean section, but it frequently causes maternal hypotension due to sympathetic blockade and the Bezold-Jarisch reflex, which can threaten both mother and baby.
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Section
- Trial name
- NCT07886151
- Testing
- Ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Post-Dural Puncture Headache
Bilateral Sphenopalatine Ganglion Block With or Without Bilateral Greater Occipital Nerve Block for Treatment of Obstetric Post-Dural Puncture Headache
Post-dural puncture headache is a common complication, following neuraxial techniques. The obstetric population is particularly prone to PDPH. Therefore, treatment of PDPH is a key issue in obstetric anesthesia.
- Trial name
- NCT04844229
- Testing
- Bilateral transnasal sphenopalatine ganglion block., Bilateral ultrasound guided greater occipital nerve block.
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Orthopedic Surgery
New Methods to Detect a Decrease in Heart Function
The purpose of this study was to evaluate the changes in heart function during onset of spinal anesthesia using a new and less invasive method, the LidcoTMplus.
- Trial name
- NCT00192894
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Obesity, Spinal Surgery
Haemodynamic Changes During Anaesthesia in the Prone Position, Evaluated Using Transoesophageal Ultrasound
Transoesophageal ultrasound examination before and after prone position.
- Conditions
- Obesity, Spinal Surgery, Anaesthesia, Changes in Left and Right Ventricle Dimension
- Trial name
- NCT02595788
- Testing
- Change from supine to prone position
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Hypotension, Controlled, Anaesthesia, Spinal
Non Invasive Haemodynamics in Neuraxial Anaesthesia Hypotension
Spinal (or neuraxial) anaesthesia is still considered the first choice technique for elective Caesarean section as simple, quick, reliable and cheap.
- Conditions
- Hypotension, Controlled, Anaesthesia, Spinal, Caesarean Section
- Trial name
- NIHNAH (NCT03653442)
- Where
- Italy
- Volunteers
- 55 people
- Sponsor
- Papa Giovanni XXIII Hospital
Total Hip Arthroplasty
Spinal Anesthesia in Total Hip Arthroplasty
Spinal anesthesia is commonly used in patients undergoing total hip replacements. The purpose of this study is to compare lidocaine to bupivacaine spinal anesthesia in patients having a total hip arthroplasty (THA).
- Trial name
- NCT02818894
- Testing
- Lidocaine, Bupivacaine
- Where
- 2 sites in United States
- Volunteers
- 135 people
- Sponsor
- Thomas L Bradbury
Pain
Selective Unilateral Spinal Anesthesia Versus Selective Sensory Spinal Anesthesia for Knee Arthroscopy Surgery
Background: Selective unilateral spinal anesthesia is the gold standard spinal anesthesia technique for knee arthroscopy. Selective sensory spinal anesthesia has recently been validated for this surgery.
- Trial name
- NCT01356797
- Testing
- hypobaric levobupivacaine with fentanyl, hyperbaric bupivacaine 0,5%
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- USP Hospital La Colina