Clinical trials: Anesthesia Time
Spinal Anesthesia, Cesarean Section
The Role of Carotid Flow Time-Based Fluid Administration in Caesarean Section
It has been reported that corrected carotid flow time (FTc) may indicate the responsiveness of spontaneously breathing patients to fluid therapy.
- Trial name
- NCT06048497
- Testing
- Corrected carotid flow time measurement guided fluid preload
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Cukurova University
Residual Paralysis, Post Anesthesia, Postoperative Complications
Predicting Neuromuscular Recovery in Surgical Patients Using Machine Learning
Despite emerging efforts to decrease residual paralysis and postoperative complications with the use of quantitative neuromuscular monitoring and reversal agents their incidences remain high.
- Conditions
- Residual Paralysis, Post Anesthesia, Postoperative Complications, Neuromuscular Blockade, Quantitative Neuromuscular Monitoring
- Trial name
- PINES (NCT05471882)
- Where
- 2 sites in Germany
- Volunteers
- 240,000 people
- Sponsor
- University Hospital Ulm
Deep Hypnotic Time, Emergence Time
Comparison of DHT Duration in Geriatric Patients Using BIS Monitoring
Without adequate monitoring, administration of anesthetic agents can create unnecessary deeper anesthetic plane in geriatric population.
- Conditions
- Deep Hypnotic Time, Emergence Time, Geriatric Population, General Anesthesia
- Trial name
- NCT06394362
- Testing
- Bispectral index monitor
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Intraoperative Awareness, General Anesthesia
Study to Determine if Patients Exposed to General Anesthesia Significant Numbers of Times Would Increase the Risk for Intraoperative Awareness.
This study will detect whether prior exposure to general anesthesia multiple times is associated with an increased incidence of awareness with explicit recall (AWR).
- Trial name
- EXPLICIT-RCL (NCT05857618)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Chicago
Obesity, Bariatric Surgery
Swap Anesthetic Versus Continuous Desflurane in Adults Undergoing Bariatric Surgery
This randomized, parallel-group, non-inferiority clinical trial aims to evaluate whether an anesthetic swap strategy consisting of sevoflurane followed by desflurane 30 minutes before the end of surgery is non-inferior to…
- Trial name
- SWAP (NCT07748247)
- Testing
- Desflurane, Sevoflurane-Desflurane
- Where
- Chile
- Volunteers
- 82 people
- Sponsor
- Clínica Dávila
Patient Safety, Anesthesia
Impact of Production Pressure in the Block Room on Patient Safety
This randomized, single blinded simulation based study investigates the impact that production pressure can have on the safety of patients undergoing regional anesthesia.
- Trial name
- NCT04846660
- Testing
- Production pressure
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Effect of Anesthesia in Postoperative Pain, Effect of Anesthesia in Extubation Time
Opioid Versus Non-opioid Anesthesia for Ambulatory Surgery in Children
The investigators intend to study the safety and effectiveness of opioid free anesthesia compared to opioid anesthesia in ambulatory surgery in children, regarding postoperative pain, hemodynamic stability, agitation and…
- Conditions
- Effect of Anesthesia in Postoperative Pain, Effect of Anesthesia in Extubation Time, Effect of Anesthesia in Discharge Time From Postanesthesia Care Unit, Effect of Anesthesia in Postoperative Adverse Events
- Trial name
- NCT03979469
- Testing
- Ketamine, dexmedetomidine, fentanyl, remifentanil
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Athens General Children's Hospital "Pan. & Aglaia Kyriakou"
Spinal Anesthesia Duration
Comparative Analysis of Intraoperative Effect Dexmedetomidine and Fentanyl as an Adjuvant to Heavy Bupivacaine in Spinal Anaesthesia in Lower Limb Orthopedic Surgeries to Evaluate the Hemodynamic Stability and Onset and Duration of Motor Block of Using Intrathecal Dexmedetomidine and Fentanyl
Spinal anesthesia is the most widely employed procedure for lower limb orthopedic operations, as it is very cost-effective and simple to apply.
- Trial name
- NCT07078201
- Testing
- Dexmedetomidine, fentanyl
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Nashwa Ahmed
Total Hip Arthroplasty (THA), Intrathecal Anesthesia
Assessing the Time-Course of Dexmedetomidine-Induced Analgesia Via EEG
Objective: To investigate the temporal dynamics of dexmedetomidine's analgesic effects in the brain using EEG. Methods: Eligible patients scheduled for total hip arthroplasty under intrathecal anesthesia received a continuous…
- Conditions
- Total Hip Arthroplasty (THA), Intrathecal Anesthesia, Hip Osteoarthritis
- Trial name
- NCT06946277
- Testing
- Preemptive Analgesia Of Dexmedetomidine
- Where
- China
- Volunteers
- 20 people
- Sponsor
- China International Neuroscience Institution
Urinary Retention, Cesarean Section Complications
Duration of Urinary Catheter Treatment After Cesarean Delivery Under Spinal Anesthesia
In this study a total of 150 parturients undergoing cesarean delivery under spinal anesthesia will be randomized to have their urinary catheters kept in place for 8, 10 or 12 hours.
- Trial name
- NCT05396430
- Testing
- Urinary catheter
- Where
- Finland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Women's Hospital HUS
Emergence Delirium, Extubation Time
Dexmedetomidine Reduces Emergence Delirium in Children Undergoing Tonsillectomy With Propofol Anesthesia
Dexmedetomidine (DEX) is safe and effective in reducing ED following sevoflurane anesthesia. The investigators intend to study the efficacy of DEX in reducing ED in children undergoing tonsillectomy with and without adenoidectomy…
- Conditions
- Emergence Delirium, Extubation Time, Heart Rate, Postoperative Analgesia
- Trial name
- NCT03131375
- Testing
- Dexmedetomidine, Normal saline, Bispectral index
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Athens General Children's Hospital "Pan. & Aglaia Kyriakou"
Regional Anesthesia Block
A Comparing Transversalis Fascia Plane Block and Quadratus Lumborum Block for Post-Cesarean Pain Management: Efficacy, Execution Time, and Practicality
Transversalis Fascia Plane Block (TFPB) and Quadratus Lumborum Block (QLB) provide superior analgesia to Transversus Abdominis Plane Block (TAPB) for post-cesarean pain management.
- Trial name
- NCT06874569
- Testing
- TAP Block:, TFP Block:, QLB:
- Where
- Egypt
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Aswan University
Anesthesia
Comparison of Sugammadex Administered at 1-2 Post Tetanic Counts (PTCs) or Better With Neostigmine Administered as Per Standard of Care to Reverse Rocuronium-Induced Neuromuscular Blockade in Adults Undergoing Elective Open Abdominal Procedure (19.4.334) (P05774)
The primary purpose of this study is to compare the incidence of residual neuromuscular blockade at the time of tracheal extubation after reversal of rocuronium bromide-induced neuromuscular blockade by 4 mg/kg sugammadex with…
- Trial name
- NCT00675792
- Testing
- Sugammadex, Neostigmine, Rocuronium
- Volunteers
- 100 people
- Sponsor
- Merck Sharp & Dohme LLC
Anesthesia, Surgery
Time Prediction for Complete Recovery From Neuromuscular Blockade After Visual Recovery With Double Burst Stimulation
The purpose is to calculate the time for an optimal recovery (T4/T1 > 0.9) from the moment when 2 responses to double burst stimulation are visually identical and this for 95% of patients.
- Trial name
- DBS PREDICTION (NCT02893436)
- Testing
- Surgery with tracheal intubation curarisation
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Central Hospital, Nancy, France
Anesthesia, Conduction, Brachial Plexus Blockade
Comparison of Sympathetic Blockade Duration in Brachial Plexus Blocks Performed by Different Methods
This prospective comparative study will evaluate the sympathetic effects of ultrasound-guided infraclavicular versus supraclavicular brachial plexus blocks in adults undergoing upper-extremity surgery.
- Conditions
- Anesthesia, Conduction, Brachial Plexus Blockade, Sympathetic Blockade
- Trial name
- NCT07326436
- Testing
- Supraclavicular brachial plexus block, Infraclavicular brachial plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bozyaka Training and Research Hospital
Intravenous Cannulation, Sevoflurane Induction
Intravenous Cannulation In Children During Sevoflurane Induction
The early placement of an intravenous (iv) line in children anesthetized with halothane has been shown safe and acceptable compared with later placement. However, there's not well known with sevoflurane use (2).
- Conditions
- Intravenous Cannulation, Sevoflurane Induction, Child
- Trial name
- NCT03851692
- Testing
- Intravenous Cannulation (iv placement)
- Volunteers
- 90 people
- Sponsor
- University Hospital Fattouma Bourguiba
Spinal Fusion Acquired, Spinal Stenosis
Intraoperative Infusion of Precedex to Reduce Length of Stay After Lumbar Spine Fusion
Major lumbar spine surgery causes inflammation, soreness and swelling that can delay discharge from the hospital. Dexmedetomidine (DEX) has been shown to have anti-inflammatory effects.
- Conditions
- Spinal Fusion Acquired, Spinal Stenosis, Lesions of Lumbosacral Intervertebral Disc, Spinal Diseases
- Trial name
- DEXREDLOS (NCT00808665)
- Testing
- Dexmedetomidine, 0.9% Saline
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Vanderbilt University Medical Center
ENT Surgery, Gynecological Surgery
Medico-economic Evaluation of Subcutaneous Automatic Resorbable Staples Device
A surgery made by an external incision requires to stitch the subcutaneous plans, usually performed using absorbable synthetic sutures hold on wire needle.
- Conditions
- ENT Surgery, Gynecological Surgery, Plastic Surgery
- Trial name
- S2CARA (NCT01546272)
- Testing
- Insorb resorbable staples, Monocryl resorbable wire
- Where
- 24 sites in France
- Volunteers
- 664 people
- Sponsor
- Nantes University Hospital
Acupuncture
Different Stimuli of Transcutaneous Electric Acupoint Stimulation(TEAS) on Acupuncture Anesthesia
To determine whether treating by transcutaneous electrical acupoint stimulation (TEAS) combined with general anesthetic during peri-operative could alleviate the dosage of anesthetic drugs compared with control and sham group.
- Trial name
- TEAS (NCT02597530)
- Testing
- TEAS
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- wangqiang
Labour Analgesia, Epidural Anaesthesia, Duration of Labour
Impact of Timing of Neuraxial Analgesia on Obstetric, Anesthesiologic and Neonatal Outcomes in Induced Labour
The aim of this observational study is to assess the effect of early labour analgesia on obstetric and neonatal outcomes in induced labour in primiparous women with a full-term pregnancy whose labour was induced with a Cook…
- Conditions
- Labour Analgesia, Epidural Anaesthesia, Duration of Labour, Labor, Induced
- Trial name
- TAIL (NCT06886555)
- Testing
- Epidural analgesia for labour pain
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia